Neurology Clinical Trials

Epilepsy

1. A Phase 3, Randomized, Double-Blind, Parallel, Placebo-Controlled, Multicenter Study, with Optional Open-Label Continuation, of the Efficacy and Safety of Vanquix Auto-Injector (Diazepam Injection) for the Management of Selected, Refractory Patients with Epilepsy who Require Intermittent Medical Intervention to Control Episodes of Acute Repetitive Seizures
2. Lamotrigine Extended-Release in Elderly Patients with Epilepsy
3. A Historical-controlled, Multicenter, Double-Blind, Randomized Trial to Assess the Efficacy and Safety of Conversion to Lacosamide 400 mg/day Monotherapy in Subjects with Partial-onset Seizures

Migraine

1. PREMIUM Trial Prospective Randomized investigation to Evaluate incidence of headache reduction in subjects with Migraine and PFO Using the AMPLATZER PFO Occluder compared to Medical Management
2. A migraine study testing investigational inhaled DHE (dihydroergotamine), an already FDA approved medication when given in other methods of administration.

Multiple Sclerosis

1. Comparing investigational doses of Alemtuzumab versus Rebif in patients with relapsing remitting MS who have relapsed on therapy
2. Comparing, two annual cycles of intravenous Alemtuzumab to three-times weekly subcutaneious Interferon Beta 1-a (Rebif) in treatment naive patients with relapsing-remitting multiple sclerosis
3. Add on cladribine tablet therapy versus placebo to MS subjects actively relapsing while on interferon therapy

Neuromuscular

1. A study of patients with Myasthenia Gravis receiving treatment with surgery and medication compared to treatment with medication alone
2. ATS Study Testing Potassium and Acetazolamide
3. Trial of Mexiletine in Non-Dystrophic Myotonia
4. Periodic Paralysis Study
5. Pathogenesis and Progression Myotonic Dystrophy
6. Clinical Outcome Measures in Friedreich's Ataxia
7. Observational Study of Patients with Episodic Ataxia
8. Cellular and Molecular Pathophysiology of Facioscapulohumeral Dystrophy (FSHD) [also called the "CAMP Study"]

Parkinson's Disease

1. Kinematics of reaching and dyskinesias in Parkinson Disease
2. Sensorimotor integration in Parkinson's Disease
3. Study of Duloxetine for Depression in Parkinson's Disease
4. Phase 2 Safety and Efficacy Study Evaluating Glutamic Acid Decarboxylase Gene Transfer to Subthalamic Nuclei in Subjects with Advanced Parkinson's Disease
5. A Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of Three Doses of Aplindore MR (1, 3 and 6 mg Twice Daily) in Patients with Early Parkinson's Disease
6. The Validation of Anxiety Rating Scales in Parkinson's Disease
7. Cognitive Deficits and Mood Disorders in Parkinson's Disease