Wilson's Disease; hepatolenticular degeneration; Kayser-Fleischer ring: Deposition of copper near the limbus of the cornea (corneo-scleral margin) in Wilson's disease causes a ring, known as the Kayser-Fleischer ring. It is characteristic of Wilson's disease. There is also cirrhosis of the liver and degeneration of the basal ganglia in the brain. It is due to decreased ceruloplasmin with deposition of copper into organs.