Clinical Trials

RTOG 0574:
A study of the role of whole brain irradiation plus radiosurgery for brain metastases

The North Central Cancer Treatment Group (NCCTG) and the Radiation Therapy Oncology Group (RTOG) are conducting this study. The purpose of this research study is to compare overall survival and to compare the effects (good and bad) of radiosurgery (SRS) (a form of radiotherapy with tightly focused, precise beams of radiation) to radiosurgery plus whole brain radiation therapy (WBRT) on you and your brain metastases. There may be microscopic tumor deposits that are not yet visible on imaging (the MRI scan) that may appear at some point in the future. This research study is being done to find out if adding WBRT to SRS will offer any additional benefit to receiving SRS alone in treating these possible microscopic tumor deposits in the brain. It is not known whether more treatment will be better or worse. The standard of care for brain metastases is radiation therapy given as WBRT alone, WBRT plus SRS, or SRS alone.

For more info, contact Cindy Gu at 585-275-2525