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MADIT-RIT Delivers Major Change in Defibrillator Therapy
Since the 1990’s, the Multicenter Automatic Defibrillator Implantation Trial (MADIT) research group, led by Professor Arthur J. Moss, M.D., has shaped the use of implantable cardioverter defibrillators and cardiac resynchronization therapy defibrillators worldwide. The group’s newest study, MADIT-RIT (Reduce Inappropriate Therapy), delivers more practice-changing results that will make the utilization of ICDs and CRT-Ds safer, more effective, and better tolerated by patients.
Arthur J. Moss, M.D., Professor of Cardiology at the University of Rochester Medical Center, reviews the findings and implications of the MADIT-RIT trial -- the first large-scale, randomized study designed to evaluate specific programming features to reduce inappropriate therapy in patients with ICDs. In the study, published in the New England Journal of Medicine, Dr. Moss and his team reveal a new, simple formula that dramatically reduced inappropriate therapies and increased survival in patients with heart disease.
Previous studies by the Multicenter Automatic Defibrillator Implantation Trial (MADIT) research group:
- Landmark MADIT-CRT Trial Yields More Information on Treatment Benefits in Patients with Mild Heart Failure
- Rochester-Led Study Leads to Recommendation for Use of Heart Failure Treatment Nationwide
- Trial Published in the New England Journal of Medicine Reports on New Therapy that Prevents Heart Failure
- New Therapy Found To Prevent Heart Failure
- ICDs Extend the Lives of Heart Attack Survivors by a Year: Study
- Implantable Device Reduces Death by One-Third
- Implanted Defibrillators: How Well Do They Work?