$7.8 Million NIH Grant Will Study Interactions Between Blood Cells, Blood Vessel Walls

October 26, 1998

A team of scientists from the University of Rochester Medical Center has received a five-year, $7.8 million grant from the National Institutes of Health to study the interactions between blood cells and blood vessel walls over a five-year period.

The research team will study the ways in which red and white blood cells respond to signals generated by infection or injury, and how these responses affect cell properties and blood flow in the smallest blood vessels in the body. Many disease processes involve changes in blood flow properties, as well as changes in the interaction between blood cells and the vessel wall. It is expected that these studies will contribute information that will ultimately prove useful in the development of new therapies to treat cardiovascular disease, cancer metastasis, and other related illnesses.

The team is composed of Richard E. Waugh, Ph.D., and Ingrid H. Sarelius, Ph.D. from the Department of Pharmacology and Physiology, Philip Knauf, Ph.D., from the Department of Biochemistry and Biophysics, several other UR researchers, and collaborators at the University of Pennsylvania.

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