URMC Joins International Prostate Cancer Prevention Study

Healthy Men Needed for Long Term SELECT Trial

November 29, 2001

Researchers at the University of Rochester Medical Center are looking for healthy men age 55 and older to participate in the largest prostate cancer prevention study launched this fall by the National Cancer Institute and the Southwest Oncology Group.

The Selenium and Vitamin E Cancer Prevention Trial, known as SELECT, will determine if these two dietary supplements can protect against prostate cancer, one of the most common forms of cancer in men.

SELECT is the first study designed to look specifically at the effects of vitamin E and selenium, both separately and together, in preventing prostate cancer. URMC is one of 400 sites in the United States, Puerto Rico and Canada participating in this study, which will take up to 12 years to complete. It is the only area center to offer this study and the university is looking for 150 to 200 men who with no previous history of prostate irregularities.

"Previous studies have hinted that selenium and vitamin E might prevent prostate cancer and this study could give us the conclusive answer," said Edward Messing, M.D., chairman of the Department of Urology at URMC and deputy director of the James P. Wilmot Cancer Center.

An informational meeting will be held for men interested in the study from 7 to 8 p.m., Wednesday, Dec. 5th, at the University of Rochester Medical Center's Helen Wood Hall Lounge, located on Crittenden Boulevard. Participants will view a video and learn about study eligibility requirements.

This year, 198,100 Americans will be diagnosed with prostate cancer and more than 31,500 men are expected to die of the disease. Risk factors for the disease include being over age 50 for black men, or 55 for white men, and having a father or brother with prostate cancer.

Preventing disease is critical to individual and community wellness. Prevention programs, like the SELECT study, are an integral part of Project Believe, the Strong Health effort to create the healthiest community by the year 2020.

Men eligible to participate in the SELECT study must have a Prostatic Specific Antigen (PSA) level below 4.0 and have no history of prostate cancer.

Participants will visit URMC every six months throughout the duration of the study. They will not have to change their diet in any way, but they must stop taking supplements they buy themselves that contain any selenium or vitamin E. This study will follow men for at least seven years to see if the supplements are effective in prostate cancer prevention.

For more information, call (585) 275-0126.

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Leslie White
(585) 273-1119
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