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Patricia M. Rodier, Ph.D.
Dr. Rodier received her A.B. in Psychology from Sweet Briar College
in 1966. She earned her Master's degree and Ph.D. in Experimental Psychology
from the University of Virginia (1969, 1970), then spent two years as
a postdoctoral fellow in Anatomy at the same university, before joining
the faculty of Anatomy in 1972. In 1980, she moved to the University
of Rochester. Since 1997 she has been a professor of Obstetrics and
Gynecology. She is the Director of the Rochester's NIH Collaborative
Program of Excellence in Autism and Rochester’s NIH STAART (Studies
to Advance Autism Research and Treatment) Center.
Dr. Rodier is active in several societies and has served as the
president of the Behavioral Teratology Society and as a member of
the Council of the Teratology Society. Her work as an advisor to government
agencies includes service on the Human Embryology and Development
Study Section at NIH, the FDA Food Science Advisory Board, and the
Board of Scientific Advisors of the National Toxicology Program. In
2003, she won the Warkany Award for research in birth defects from
the Teratology Society, and in 2004, she won the Bock Prize in Developmental
Biology and Genetics from The DuPont Childrens’ Hospital.
Current areas of interest:
Dr. Rodier's research has been directed at understanding how injuries
to the developing brain occur and how they are later expressed in
structure and function. She has worked with antimitotic agents to
model many different kinds of brain damage and has studied known human
teratogens, as well, including methylmercury, inhalant anesthetics,
and ethanol. Since 1994 she has concentrated on studies of the etiology
of autism, a neurodevelopmental disorder with both genetic and environmental
risk factors. With her collaborators, Dr. Rodier is studying human
populations and animal models to identify autism risk factors and
understand their mechanisms of action.
How to contact Dr. Rodier:
E-Mail Address: Patricia_Rodier@urmc.rochester.edu
Link to: Environmental Medicine
Current research and publications:
- Rodier, P.M. (2004) Environmental causes of CNS
maldevelopment. Pediatrics.,113:1076-1083.
- Conciatori M, Stodgell CJ, Hyman SL, O’Bara M, Militerni
R, Bravaccio C, Trillo S et al. (2004) Association between the HOXA1
A218G polymorphism and increased head circumference in patients
with autism. J Biol Psychiat. 55:413-419.
- Rodier, P.M. (2004) The 2003 Warkany Lecture:
Autism as a birth defect. Birth Defects Research A, 70:1-6.
- Rodier, P.M. (2002) Converging evidence for brain stem
injury in autism. Devel. Psychopathol.14: 537-557.
- Hyman, S.L., Rodier, P.M., Davidson, P. (2001) Pervasive
developmental disorders in young children. JAMA, 285:3141-3142.
- Ingram, J.L., Stodgell, C.J., Hyman, S.L., Figlewicz, D.A., Weitkamp,
L.R., Rodier, P.M. (2000) Discovery of allelic variants of
HOXA1 and HOXB1: Genetic susceptibility to autism spectrum disorders.
Teratology,62, 393-405.
- Ingram, J.L., Peckham, S.M., Tisdale, B., and Rodier, P.M.
(2000) Prenatal exposure of rats to valproic acid reproduces the
cerebellar anomalies associated with autism. Neurotoxicol. Teratol.
22:319-324.
- Rodier, P.M. (2000) The early origins of autism. Scientific
American, 282, 56-63.
- Rodier, P.M., and Hyman, S.L. (1998) Early environmental
factors in autism. MRDD Res Revs, 4, 121-128.
- Rodier, P.M., Bryson, S.E., and Welch, J.P. (1997) Minor
malformations and physical measures in autism: Data from Nova Scotia.
Teratology, 55:319-325.
- Rodier, P.M., J.L. Ingram, B. Tisdale, S. Nelson,
and J. Romano (1996) Embryological origin for autism: Developmental
anomalies of the cranial nerve motor nuclei . J. Comp. Neurol.
370:247-261.
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Updated January 4, 2005
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