Case 2: Submandibular Neck FNASorry, this was not a case of metastatic carcinoma consistent with pancreatic primary. Adenocarcinoma is typically cohesive with numerous three-dimensional groups of cells. Depending on the differentiation, the cells may have a sheet-like arrangement or disorganized "honey comb" appearance (slides 1 & 2). Additional clues to the diagnosis are intracytoplasmic mucin vacuoles, gland formation, and prominent nucleoli (slide 3). Areas of chromatin clearing may also be present. Adenocarcinomas may be focally discohesive (slide 4), however, in most cases cohesive cell groups can be found.
Metastatic Carcinoma Slide 1
Metastatic Carcinoma Slide 2
Metastatic Carcinoma Slide 3
Metastatic Carcinoma Slide 4 |
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