Patricia M. Hinkle, Ph.D.

Patricia M. Hinkle, Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 711
Rochester, NY 14642

Journal Articles

Showing all 115 journal articles available.

2013 Mar 15
Gehret AU, Hinkle PM. "siRNA screen identifies the phosphatase acting on the G protein-coupled thyrotropin-releasing hormone receptor." ACS chemical biology. 2013 Mar 15; 8(3):588-98. Epub 2012 Dec 18.
2012 Nov 16
Thal DM, Homan KT, Chen J, Wu EK, Hinkle PM, Huang ZM, Chuprun JK, Song J, Gao E, Cheung JY, Sklar LA, Koch WJ, Tesmer JJ. "Paroxetine is a direct inhibitor of g protein-coupled receptor kinase 2 and increases myocardial contractility." ACS chemical biology. 2012 Nov 16; 7(11):1830-9. Epub 2012 Aug 21.
2012 Jun 15
Christian WV, Li N, Hinkle PM, Ballatori N. "?-Subunit of the Ost?-Ost? organic solute transporter is required not only for heterodimerization and trafficking but also for function." The Journal of biological chemistry.. 2012 Jun 15; 287(25):21233-43. Epub 2012 Apr 25.
2012
Hinkle PM, Gehret AU, Jones BW. "Desensitization, trafficking, and resensitization of the pituitary thyrotropin-releasing hormone receptor." Frontiers in neuroscience. 2012 6:180. Epub 2012 Dec 13.
2011 Oct 1
Liang L, Sebag JA, Eagelston L, Serasinghe MN, Veo K, Reinick C, Angleson J, Hinkle PM, Dores RM. "Functional expression of frog and rainbow trout melanocortin 2 receptors using heterologous MRAP1s." General and comparative endocrinology. 2011 Oct 1; 174(1):5-14. Epub 2011 Aug 09.
2010 Jun 1
Gehret AU, Hinkle PM. "Importance of regions outside the cytoplasmic tail of G-protein-coupled receptors for phosphorylation and dephosphorylation." The Biochemical journal.. 2010 Jun 1; 428(2):235-45. Epub 2010 May 13.
2010 Feb
Gehret AU, Jones BW, Tran PN, Cook LB, Greuber EK, Hinkle PM. "Role of helix 8 of the thyrotropin-releasing hormone receptor in phosphorylation by G protein-coupled receptor kinase." Molecular pharmacology.. 2010 Feb; 77(2):288-97. Epub 2009 Nov 11.
2010
Sebag JA, Hinkle PM. "Regulation of G protein-coupled receptor signaling: specific dominant-negative effects of melanocortin 2 receptor accessory protein 2." Science signaling. 2010 3(116):ra28. Epub 2010 Apr 06.
2009 Sep
Jones BW, Hinkle PM. "Subcellular trafficking of the TRH receptor: effect of phosphorylation." Molecular endocrinology.. 2009 Sep; 23(9):1466-78. Epub 2009 Jun 18.
2009 Aug 21
Sebag JA, Hinkle PM. "Opposite effects of the melanocortin-2 (MC2) receptor accessory protein MRAP on MC2 and MC5 receptor dimerization and trafficking." The Journal of biological chemistry.. 2009 Aug 21; 284(34):22641-8. Epub 2009 Jun 17.
2009 Mar 5
Hinkle PM, Sebag JA. "Structure and function of the melanocortin2 receptor accessory protein (MRAP)." Molecular and cellular endocrinology.. 2009 Mar 5; 300(1-2):25-31. Epub 2008 Nov 06.
2009 Jan 2
Sebag JA, Hinkle PM. "Regions of melanocortin 2 (MC2) receptor accessory protein necessary for dual topology and MC2 receptor trafficking and signaling." The Journal of biological chemistry.. 2009 Jan 2; 284(1):610-8. Epub 2008 Nov 03.
2008 Jul
Jones BW, Hinkle PM. "Arrestin binds to different phosphorylated regions of the thyrotropin-releasing hormone receptor with distinct functional consequences." Molecular pharmacology.. 2008 Jul; 74(1):195-202. Epub 2008 Apr 15.
2008 Jan 24
Hogan N, O'Boyle KM, Hinkle PM, Kelly JA. "A novel TRH analog, Glp-Asn-Pro-D-Tyr-D-TrpNH2, binds to [3H][3-Me-His2]TRH-labelled sites in rat hippocampus and cortex but not pituitary or heterologous cells expressing TRHR1 or TRHR2." Neuroscience letters.. 2008 Jan 24; 431(1):26-30. Epub 2007 Nov 17.
2007 Nov 13
Song GJ, Jones BW, Hinkle PM. "Dimerization of the thyrotropin-releasing hormone receptor potentiates hormone-dependent receptor phosphorylation." Proceedings of the National Academy of Sciences of the United States of America.. 2007 Nov 13; 104(46):18303-8. Epub 2007 Nov 07.
2007 Jun
Scalabrino GA, Hogan N, O'Boyle KM, Slator GR, Gregg DJ, Fitchett CM, Draper SM, Bennett GW, Hinkle PM, Bauer K, Williams CH, Tipton KF, Kelly JA. "Discovery of a dual action first-in-class peptide that mimics and enhances CNS-mediated actions of thyrotropin-releasing hormone." Neuropharmacology. 2007 Jun; 52(7):1472-81. Epub 2007 Feb 28.
2007 Apr 27
Jones BW, Song GJ, Greuber EK, Hinkle PM. "Phosphorylation of the endogenous thyrotropin-releasing hormone receptor in pituitary GH3 cells and pituitary tissue revealed by phosphosite-specific antibodies." The Journal of biological chemistry.. 2007 Apr 27; 282(17):12893-906. Epub 2007 Feb 28.
2007
Sebag JA, Hinkle PM. "Melanocortin-2 receptor accessory protein MRAP forms antiparallel homodimers." Proceedings of the National Academy of Sciences of the United States of America.. 2007 104(51):20244-9. Epub 2007 Dec 12.
2006
Sebag JA, Hinkle PM. "Regulation of endogenous melanocortin-4 receptor expression and signaling by glucocorticoids." Endocrinology.. 2006 147(12):5948-55. Epub 2006 Sep 14.
2005 Nov 18
Jones BW, Hinkle PM. "Beta-arrestin mediates desensitization and internalization but does not affect dephosphorylation of the thyrotropin-releasing hormone receptor." The Journal of biological chemistry.. 2005 Nov 18; 280(46):38346-54. Epub 2005 Sep 23.
2005 Nov
Song GJ, Hinkle PM. "Regulated dimerization of the thyrotropin-releasing hormone receptor affects receptor trafficking but not signaling." Molecular endocrinology.. 2005 Nov; 19(11):2859-70. Epub 2005 Jul 14.
2004 Jul
Cook LB, Hinkle PM. "Fate of internalized thyrotropin-releasing hormone receptors monitored with a timer fusion protein." Endocrinology.. 2004 Jul; 145(7):3095-100. Epub 2004 Apr 29.
2004 Jun 15
Cook LB, Hinkle PM. "Agonist-dependent up-regulation of thyrotrophin-releasing hormone receptor protein." The Biochemical journal.. 2004 Jun 15; 380(Pt 3):815-21.
2004
Hinkle PM, Puskas JA. "Detection of G protein-coupled receptors by immunofluorescence microscopy." Methods in molecular biology.. 2004 237:127-34.
2003 Nov
Sattin A, Pekary AE, Lloyd RL, Paulson M, Meyerhoff JA, Hinkle PM, Faull K. "TRH and related peptides: homeostatic regulators of glutamate transmission?" Annals of the New York Academy of Sciences.. 2003 Nov; 1003:458-60.
2003 Sep
Cook LB, Zhu CC, Hinkle PM. "Thyrotropin-releasing hormone receptor processing: role of ubiquitination and proteasomal degradation." Molecular endocrinology.. 2003 Sep; 17(9):1777-91. Epub 2003 Jun 12.
2003 Aug
Graves TK, Hinkle PM. "Ca(2+)-induced Ca(2+) release in the pancreatic beta-cell: direct evidence of endoplasmic reticulum Ca(2+) release." Endocrinology.. 2003 Aug; 144(8):3565-74.
2003 May 30
Goubaeva F, Ghosh M, Malik S, Yang J, Hinkle PM, Griendling KK, Neubig RR, Smrcka AV. "Stimulation of cellular signaling and G protein subunit dissociation by G protein betagamma subunit-binding peptides." The Journal of biological chemistry.. 2003 May 30; 278(22):19634-41. Epub 2003 Mar 20.
2003 Feb
Graves TK, Hinkle PM. "Endoplasmic reticulum calcium storage and release in cells expressing misfolded growth hormone." Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society. 2003 Feb; 13(1):36-43.
2002 Aug 2
Zhu CC, Cook LB, Hinkle PM. "Dimerization and phosphorylation of thyrotropin-releasing hormone receptors are modulated by agonist stimulation." The Journal of biological chemistry.. 2002 Aug 2; 277(31):28228-37. Epub 2002 May 22.
2002 May 10
Hinkle PM, Pekary AE, Senanayaki S, Sattin A. "Role of TRH receptors as possible mediators of analeptic actions of TRH-like peptides." Brain research.. 2002 May 10; 935(1-2):59-64.
2001 Oct
Graves TK, Patel S, Dannies PS, Hinkle PM. "Misfolded growth hormone causes fragmentation of the Golgi apparatus and disrupts endoplasmic reticulum-to-Golgi traffic." Journal of cell science.. 2001 Oct; 114(Pt 20):3685-94.
2001 Sep
Smith J, Yu R, Hinkle PM. "Activation of MAPK by TRH requires clathrin-dependent endocytosis and PKC but not receptor interaction with beta-arrestin or receptor endocytosis." Molecular endocrinology.. 2001 Sep; 15(9):1539-48.
2001 Jan
Romoser VA, Graves TK, Wu D, Jiang H, Hinkle PM. "Calcium responses to thyrotropin-releasing hormone, gonadotropin-releasing hormone and somatostatin in phospholipase css3 knockout mice." Molecular endocrinology.. 2001 Jan; 15(1):125-35.
2001
Rapoport AP, Simons-Evelyn M, Chen T, Sidell R, Luhowskyj S, Rosell K, Obrig T, Hicks D, Hinkle PM, Nahm M, Insel RA, Abboud CN. "Flavopiridol induces apoptosis and caspase-3 activation of a newly characterized Burkitt's lymphoma cell line containing mutant p53 genes." Blood cells, molecules & diseases.. 2001 27(3):610-24.
2000 Aug 4
Yu R, Hinkle PM. "Rapid turnover of calcium in the endoplasmic reticulum during signaling. Studies with cameleon calcium indicators." The Journal of biological chemistry.. 2000 Aug 4; 275(31):23648-53.
1999 Aug 31
Xie W, Samoriski GM, McLaughlin JP, Romoser VA, Smrcka A, Hinkle PM, Bidlack JM, Gross RA, Jiang H, Wu D. "Genetic alteration of phospholipase C beta3 expression modulates behavioral and cellular responses to mu opioids." Proceedings of the National Academy of Sciences of the United States of America.. 1999 Aug 31; 96(18):10385-90.
1999 May 28
Yu R, Hinkle PM. "Signal transduction and hormone-dependent internalization of the thyrotropin-releasing hormone receptor in cells lacking Gq and G11." The Journal of biological chemistry.. 1999 May 28; 274(22):15745-50.
1999 Apr
Fliss MS, Hinkle PM, Bancroft C. "Expression cloning and characterization of PREB (prolactin regulatory element binding), a novel WD motif DNA-binding protein with a capacity to regulate prolactin promoter activity." Molecular endocrinology.. 1999 Apr; 13(4):644-57.
1998 Oct
Yu R, Ashworth R, Hinkle PM. "Receptors for thyrotropin-releasing hormone on rat lactotropes and thyrotropes." Thyroid : official journal of the American Thyroid Association. 1998 Oct; 8(10):887-94.
1998 May
Yu R, Hinkle PM. "Signal transduction, desensitization, and recovery of responses to thyrotropin-releasing hormone after inhibition of receptor internalization." Molecular endocrinology.. 1998 May; 12(5):737-49.
1998
Nelson EJ, Zinkin NT, Hinkle PM. "Fluorescence methods to assess multidrug resistance in individual cells." Cancer chemotherapy and pharmacology. 1998 42(4):292-9.
1997 Nov 7
Yu R, Hinkle PM. "Desensitization of thyrotropin-releasing hormone receptor-mediated responses involves multiple steps." The Journal of biological chemistry.. 1997 Nov 7; 272(45):28301-7.
1997 Sep
Kerper LE, Hinkle PM. "Lead uptake in brain capillary endothelial cells: activation by calcium store depletion." Toxicology and applied pharmacology.. 1997 Sep; 146(1):127-33.
1997 May 16
Romoser VA, Hinkle PM, Persechini A. "Detection in living cells of Ca2+-dependent changes in the fluorescence emission of an indicator composed of two green fluorescent protein variants linked by a calmodulin-binding sequence. A new class of fluorescent indicators." The Journal of biological chemistry.. 1997 May 16; 272(20):13270-4.
1997 May
Yu R, Hinkle PM. "Effect of cell type on the subcellular localization of the thyrotropin-releasing hormone receptor." Molecular pharmacology.. 1997 May; 51(5):785-93.
1997 Mar 28
Kerper LE, Hinkle PM. "Cellular uptake of lead is activated by depletion of intracellular calcium stores." The Journal of biological chemistry.. 1997 Mar 28; 272(13):8346-52.
1996 Jan
Shupnik MA, Weck J, Hinkle PM. "Thyrotropin (TSH)-releasing hormone stimulates TSH beta promoter activity by two distinct mechanisms involving calcium influx through L type Ca2+ channels and protein kinase C." Molecular endocrinology.. 1996 Jan; 10(1):90-9.
1996
Ashworth R, Hinkle PM. "Thyrotropin-releasing hormone-induced intracellular calcium responses in individual rat lactotrophs and thyrotrophs." Endocrinology.. 1996 137(12):5205-12.
1995 Jan 17
Ashworth R, Yu R, Nelson EJ, Dermer S, Gershengorn MC, Hinkle PM. "Visualization of the thyrotropin-releasing hormone receptor and its ligand during endocytosis and recycling." Proceedings of the National Academy of Sciences of the United States of America.. 1995 Jan 17; 92(2):512-6.
1994 Sep
Nelson EJ, Hinkle PM. "Characteristics of the Ca2+ spike and oscillations induced by different doses of thyrotropin-releasing hormone (TRH) in individual pituitary cells and nonexcitable cells transfected with TRH receptor complementary deoxyribonucleic acid." Endocrinology.. 1994 Sep; 135(3):1084-92.
1994 Aug 15
Nelson EJ, Li CC, Bangalore R, Benson T, Kass RS, Hinkle PM. "Inhibition of L-type calcium-channel activity by thapsigargin and 2,5-t-butylhydroquinone, but not by cyclopiazonic acid." The Biochemical journal.. 1994 Aug 15; 302 ( Pt 1):147-54.
1994 Mar 4
Gershengorn MC, Heinflink M, Nussenzveig DR, Hinkle PM, Falck-Pedersen E. "Thyrotropin-releasing hormone (TRH) receptor number determines the size of the TRH-responsive phosphoinositide pool. Demonstration using controlled expression of TRH receptors by adenovirus mediated gene transfer." The Journal of biological chemistry.. 1994 Mar 4; 269(9):6779-83.
1994 Jan
Hinkle PM, Osborne ME. "Cadmium toxicity in rat pheochromocytoma cells: studies on the mechanism of uptake." Toxicology and applied pharmacology.. 1994 Jan; 124(1):91-8.
1994
Nelson EJ, Hinkle PM. "Thyrotropin-releasing hormone activates Ca2+ efflux. Evidence suggesting that a plasma membrane Ca2+ pump is an effector for a G-protein-coupled Ca(2+)-mobilizing receptor." The Journal of biological chemistry.. 1994 269(49):30854-60.
1993 Sep 25
Yan Z, Hinkle PM. "Saturable, stereospecific transport of 3,5,3'-triiodo-L-thyronine and L-thyroxine into GH4C1 pituitary cells." The Journal of biological chemistry.. 1993 Sep 25; 268(27):20179-84.
1993 Aug
Straight SW, Hinkle PM, Jewers RJ, McCance DJ. "The E5 oncoprotein of human papillomavirus type 16 transforms fibroblasts and effects the downregulation of the epidermal growth factor receptor in keratinocytes." Journal of virology.. 1993 Aug; 67(8):4521-32.
1993 Jul
Hinkle PM, Nelson EJ, Haymes AA. "Regulation of L-type voltage-gated calcium channels by epidermal growth factor." Endocrinology.. 1993 Jul; 133(1):271-6.
1993 Apr
Haymes AA, Hinkle PM. "Activation of protein kinase C increases Ca2+ sensitivity of secretory response of GH3 pituitary cells." The American journal of physiology.. 1993 Apr; 264(4 Pt 1):C1020-8.
1992 Sep
Li P, Thaw CN, Sempowski GD, Gershengorn MC, Hinkle PM. "Characterization of the calcium response to thyrotropin-releasing hormone (TRH) in cells transfected with TRH receptor complementary DNA: importance of voltage-sensitive calcium channels." Molecular endocrinology.. 1992 Sep; 6(9):1393-402.
1992 Jun
Nelson EJ, Hinkle PM. "Characterization of multidrug-resistant pituitary tumor cells." Endocrinology.. 1992 Jun; 130(6):3246-56.
1992 Jun
Hinkle PM, Scammell JG, Shanshala ED. "Prolactin and secretogranin-II, a marker for the regulated pathway, are secreted in parallel by pituitary GH4C1 cells." Endocrinology.. 1992 Jun; 130(6):3503-11.
1992 May
Haymes AA, Kwan YW, Arena JP, Kass RS, Hinkle PM. "Activation of protein kinase C reduces L-type calcium channel activity of GH3 pituitary cells." The American journal of physiology.. 1992 May; 262(5 Pt 1):C1211-9.
1992 May
Spaulding SW, Smith TJ, Hinkle PM, Davis FB, Kung MP, Roth JA. "Studies on the biological activity of triiodothyronine sulfate." The Journal of clinical endocrinology and metabolism.. 1992 May; 74(5):1062-7.
1992
Hinkle PM, Shanshala ED, Nelson EJ. "Measurement of intracellular cadmium with fluorescent dyes. Further evidence for the role of calcium channels in cadmium uptake." The Journal of biological chemistry.. 1992 267(35):25553-9.
1991 Sep
Hinkle PM, Shanshala ED, Yan ZF. "Epidermal growth factor decreases the concentration of thyrotropin-releasing hormone (TRH) receptors and TRH responses in pituitary GH4C1 cells." Endocrinology.. 1991 Sep; 129(3):1283-8.
1989 Sep
Hinkle PM, Shanshala ED. "Pituitary thyrotropin-releasing hormone (TRH) receptors: effects of TRH, drugs mimicking TRH action, and chlordiazepoxide." Molecular endocrinology.. 1989 Sep; 3(9):1337-44.
1989 Sep
Phillips WJ, Enyeart JJ, Hinkle PM. "Pituitary thyrotropin-releasing hormone receptors: local anesthetic effects on binding and responses." Molecular endocrinology.. 1989 Sep; 3(9):1345-51.
1989 Apr
Phillips WJ, Hinkle PM. "Solubilization and characterization of pituitary thyrotropin-releasing hormone receptors." Molecular pharmacology.. 1989 Apr; 35(4):533-40.
1989 Feb
Kaji H, Hinkle PM. "Attenuation of thyroid hormone action by 1,25-dihydroxyvitamin D3 in pituitary cells." Endocrinology.. 1989 Feb; 124(2):930-6.
1989
Hinkle PM. "Pituitary TRH receptors." Annals of the New York Academy of Sciences.. 1989 553:176-87.
1988 Nov 5
Day RN, Hinkle PM. "Prolactin synthesis in cultured pituitary cells is chloride-dependent." The Journal of biological chemistry.. 1988 Nov 5; 263(31):15922-7.
1988 Nov 5
Day RN, Hinkle PM. "Osmotic regulation of prolactin secretion. Possible role of chloride." The Journal of biological chemistry.. 1988 Nov 5; 263(31):15915-21.
1988 Nov
Hinkle PM, Jackson AE, Thompson TM, Zavacki AM, Coppola DA, Bancroft C. "Calcium channel agonists and antagonists: effects of chronic treatment on pituitary prolactin synthesis and intracellular calcium." Molecular endocrinology.. 1988 Nov; 2(11):1132-8.
1988 Sep 25
Kaji H, Casnellie JE, Hinkle PM. "Thyrotropin releasing hormone action in pituitary cells. Protein kinase C-mediated effects on the epidermal growth factor receptor." The Journal of biological chemistry.. 1988 Sep 25; 263(27):13588-93.
1988 May
Day RN, Hinkle PM. "Transient dopaminergic inhibition of prolactin release from hybrid cells derived by fusion of normal rat pituitary and GH4C1 tumor cells." Endocrinology.. 1988 May; 122(5):2165-73.
1987 Nov
Kaji H, Hinkle PM. "Regulation of thyroid hormone receptors and responses by thyrotropin-releasing hormone in GH4C1 cells." Endocrinology.. 1987 Nov; 121(5):1697-704.
1987 Jul
Enyeart JJ, Sheu SS, Hinkle PM. "Pituitary Ca2+ channels: blockade by conventional and novel Ca2+ antagonists." The American journal of physiology.. 1987 Jul; 253(1 Pt 1):C162-70.
1987 Mar 5
Enyeart JJ, Sheu SS, Hinkle PM. "Dihydropyridine modulators of voltage-sensitive Ca2+ channels specifically regulate prolactin production by GH4C1 pituitary tumor cells." The Journal of biological chemistry.. 1987 Mar 5; 262(7):3154-9.
1987 Feb
Kaji H, Hinkle PM. "Epidermal growth factor decreases thyroid hormone receptors and attenuates thyroid hormone responses in GH4C1 cells." Endocrinology.. 1987 Feb; 120(2):537-43.
1987
Hinkle PM, Kinsella PA, Osterhoudt KC. "Cadmium uptake and toxicity via voltage-sensitive calcium channels." The Journal of biological chemistry.. 1987 262(34):16333-7.
1986 Jul 1
Hinkle PM, Hewlett EL, Gershengorn MC. "Thyroliberin action in pituitary cells is not inhibited by pertussis toxin." The Biochemical journal.. 1986 Jul 1; 237(1):181-6.
1986 Jan
Enyeart JJ, Aizawa T, Hinkle PM. "Interaction of dihydropyridine Ca2+ agonist Bay K 8644 with normal and transformed pituitary cells." The American journal of physiology.. 1986 Jan; 250(1 Pt 1):C95-102.
1986
Hinkle PM, Kinsella PA. "Thyroid hormone induction of an autocrine growth factor secreted by pituitary tumor cells." Science.. 1986 234(4783):1549-52.
1985 May
Enyeart JJ, Aizawa T, Hinkle PM. "Dihydropyridine Ca2+ antagonists: potent inhibitors of secretion from normal and transformed pituitary cells." The American journal of physiology.. 1985 May; 248(5 Pt 1):C510-9.
1985 Mar
Aizawa T, Hinkle PM. "Differential effects of thyrotropin-releasing hormone, vasoactive intestinal peptide, phorbol ester, and depolarization in GH4C1 rat pituitary cells." Endocrinology.. 1985 Mar; 116(3):909-19.
1985 Jan
Aizawa T, Hinkle PM. "Thyrotropin-releasing hormone rapidly stimulates a biphasic secretion of prolactin and growth hormone in GH4C1 rat pituitary tumor cells." Endocrinology.. 1985 Jan; 116(1):73-82.
1984 Oct
Hinkle PM, Phillips WJ. "Thyrotropin-releasing hormone stimulates GTP hydrolysis by membranes from GH4C1 rat pituitary tumor cells." Proceedings of the National Academy of Sciences of the United States of America.. 1984 Oct; 81(19):6183-7.
1984 Aug 16
Enyeart JJ, Hinkle PM. "The calcium agonist Bay K 8644 stimulates secretion from a pituitary cell line." Biochemical and biophysical research communications.. 1984 Aug 16; 122(3):991-6.
1984 Jul
Halpern J, Hinkle PM. "Characterization of thyroid hormone stimulation of uridine uptake by rat pituitary tumor cells." Endocrinology.. 1984 Jul; 115(1):95-101.
1984 Mar 25
Hinkle PM, Kinsella PA. "Regulation of thyrotropin-releasing hormone binding by monovalent cations and guanyl nucleotides." The Journal of biological chemistry.. 1984 Mar 25; 259(6):3445-9.
1983
Halpern J, Hinkle PM. "Binding and internalization of epidermal growth factor by rat pituitary tumor cells." Molecular and cellular endocrinology.. 1983 33(2-3):183-96.
1982 May 25
Hinkle PM, Kinsella PA. "Rapid temperature-dependent transformation of the thyrotropin-releasing hormone-receptor complex in rat pituitary tumor cells." The Journal of biological chemistry.. 1982 May 25; 257(10):5462-70.
1982 May
Hinkle PM, Goh KB. "Regulation of thyrotropin-releasing hormone receptors and responses by L-triiodothyronine in dispersed rat pituitary cell cultures." Endocrinology.. 1982 May; 110(5):1725-31.
1982 Mar
Halpern J, Hinkle PM. "Evidence for an active step in thyroid hormone transport to nuclei: drug inhibition of L-125I-triiodothyronine binding to nuclear receptors in rat pituitary tumor cells." Endocrinology.. 1982 Mar; 110(3):1070-2.
1981 Nov 25
Berk BC, Hinkle PM. "Purification of a stimulator of microtubule assembly from bovine thyroid." The Journal of biological chemistry.. 1981 Nov 25; 256(22):11859-65.
1981 Jan
Hinkle PM, Perrone MH, Schonbrunn A. "Mechanism of thyroid hormone inhibition of thyrotropin-releasing hormone action." Endocrinology.. 1981 Jan; 108(1):199-205.
1981 Jan
Halpern J, Hinkle PM. "Direct visualization of receptors for thyrotropin-releasing hormone with a fluorescein-labeled analog." Proceedings of the National Academy of Sciences of the United States of America.. 1981 Jan; 78(1):587-91.
1980 Apr 10
Berk BC, Hinkle PM. "Thyroid and brain microtubules: a comparison." The Journal of biological chemistry.. 1980 Apr 10; 255(7):3186-93.
1980 Mar
Hinkle PM, Lewis DG, Greer TL. "Thyrotropin-releasing hormone-receptor interaction in GH3 pituitary cells." Endocrinology.. 1980 Mar; 106(3):1000-5.
1980 Feb
Perrone MH, Greer TL, Hinkle PM. "Relationships between thyroid hormone and glucocorticoid effects in GH3 pituitary cells." Endocrinology.. 1980 Feb; 106(2):600-5.
1980
Vriend J, Hinkle PM, Knigge KM. "Evidence for a thyrotropin-releasing hormone inhibitor in the pineal gland." Endocrinology.. 1980 107(6):1791-7.
1979 Jul 27
Rupnow JH, Hinkle PM, Dixon JE. "A macromolecule which gives rise to thyrotropin releasing-hormone." Biochemical and biophysical research communications.. 1979 Jul 27; 89(2):721-8.
1979 May 25
Hinkle PM, Perrone MH, Greer TL. "Thyroid hormone action in pituitary cells. Differences in the regulation of thyrotropin-releasing hormone receptors and growth hormone synthesis." The Journal of biological chemistry.. 1979 May 25; 254(10):3907-11.
1978 Jul 25
Perrone MH, Hinkle PM. "Regulation of pituitary receptors for thyrotropin-releasing hormone by thyroid hormones." The Journal of biological chemistry.. 1978 Jul 25; 253(14):5168-73.
1978 Jul 3
Hinkle PM, Lewis DG. "Solubilization of pituitary receptors for thyrotropin-releasing hormone." Biochimica et biophysica acta.. 1978 Jul 3; 541(3):347-59.
1977 Apr
Hinkle PM, Tashjian AH. "Adenylyl cyclase and cyclic nucleotide phosphodiesterases in GH-Strains of rat pituitary cells." Endocrinology.. 1977 Apr; 100(4):934-44.
1975 Aug 26
Hinkle PM, Tashjian AH. "Thyrotropin-releasing hormone regulates the number of its own receptors in the GH3 strain of pituitary cells in culture." Biochemistry.. 1975 Aug 26; 14(17):3845-51.
1975 Aug
Hinkle PM, Tashjian AH. "Degradation of thyrotropin-releasing hormone by the GH3 strain of pituitary cells in culture." Endocrinology.. 1975 Aug; 97(2):324-31.
1975 Feb 17
Imae T, Fasman GD, Hinkle PM, Tashjian AH. "Intrinsic tryptophan fluorescence of membranes of GH3 pituitary cells: quenching by thyrotropin-releasing hormone." Biochemical and biophysical research communications.. 1975 Feb 17; 62(4):923-32.
1974 Jun
Hinkle PM. "Uses of prolactin- and growth hormone-producing rat pituitary tumor cells in culture." Lloydia. 1974 Jun; 37(2):192-5.
1974 May 25
Hinkle PM, Woroch EL, Tashjian AH. "Receptor-binding affinities and biological activities of analogs of thyrotropin-releasing hormone in prolactin-producing pituitary cells in culture." The Journal of biological chemistry.. 1974 May 25; 249(10):3085-90.
1973 Sep 10
Hinkle PM, Tashjian AH. "Receptors for thyrotropin-releasing hormone in prolactin producing rat pituitary cells in culture." The Journal of biological chemistry.. 1973 Sep 10; 248(17):6180-6.
1972 May 26
Levine L, Hinkle PM, Voelkel EF, Tashjian AH. "Prostaglandin production by mouse fibrosarcoma cells in culture: inhibition by indomethacin and aspirin." Biochemical and biophysical research communications.. 1972 May 26; 47(4):888-96.
1971 Jul 6
Hinkle PM, Kirsch JF. "Demonstration of a change in the rate-determining step in papain- and ficin-catalyzed acyl-transfer reactions." Biochemistry.. 1971 Jul 6; 10(14):2717-26.

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