Research Bio
Dr. Sherman has been investigating various broad aspects of gene expression in yeast, as means to determine processes operating in eukaryotic cells. By using iso-1-cytochrome c as a model system, general principles have been uncovered, including those involved in transcription, translation, co-translational and post-translational modification, mitochondrial import, heme attachment, enzymatic functions and protein degradation. Currently, efforts have been directed toward understanding the relationships between protein structure, protein modifications and degradation in vivo, and in uncovering new degradation systems in mitochondria.
2009
Polevoda, B.; Hoskins, J.; Sherman, F.;. "Properties of Nat4, an N{alpha}-Acetyltransferase of Saccharomyces cerevisae that Modifies N termini of Histones H2A and H4". Mol Cell Biol. 2009; . |
2008
Kabir, M. A.; Sherman, F.;. "Overexpressed ribosomal proteins suppress defective chaperonins in Saccharomyces cerevisiae". FEMS Yeast Res. 2008; 8(38): 1236-44. |
2007
Polevoda, B.; Brown, S.; Cardillo, T. S.; Rigby, S.; Sherman, F.;. "Yeast N(alpha)-terminal acetyltransferases are associated with ribosomes". J Cell Biochem. 2007; . |
2007
Polevoda, B.; Sherman, F.;. "Methylation of proteins involved in translation". Mol Microbiol. 2007; 65(33): 590-606. |
2006 Jul 18
Das B, Das S, Sherman F. "Mutant LYS2 mRNAs retained and degraded in the nucleus of Saccharomyces cerevisiae." Proceedings of the National Academy of Sciences of the United States
of America. 2006 Jul 18; 103(29):10871-6. Epub 2006 Jul 10. |
