Barbara H. Iglewski, Ph.D.

Barbara H. Iglewski, Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 672
Rochester, NY 14642

Journal Articles

Showing all 153 journal articles available.

2009 Oct
Van Alst NE, Wellington M, Clark VL, Haidaris CG, Iglewski BH. "Nitrite reductase NirS is required for type III secretion system expression and virulence in the human monocyte cell line THP-1 by Pseudomonas aeruginosa." Infection and immunity.. 2009 Oct; 77(10):4446-54. Epub 2009 Aug 03.
2008
Wagner VE, Iglewski BH. "P. aeruginosa Biofilms in CF Infection." Clinical reviews in allergy & immunology. 2008 35(3):124-34.
2007 Nov
Morici LA, Carterson AJ, Wagner VE, Frisk A, Schurr JR, Höner zu Bentrup K, Hassett DJ, Iglewski BH, Sauer K, Schurr MJ. "Pseudomonas aeruginosa AlgR represses the Rhl quorum-sensing system in a biofilm-specific manner." Journal of bacteriology.. 2007 Nov; 189(21):7752-64. Epub 2007 Aug 31.
2007 Aug
Van Alst NE, Picardo KF, Iglewski BH, Haidaris CG. "Nitrate sensing and metabolism modulate motility, biofilm formation, and virulence in Pseudomonas aeruginosa." Infection and immunity.. 2007 Aug; 75(8):3780-90. Epub 2007 May 25.
2007 Jun
Li LL, Malone JE, Iglewski BH. "Regulation of the Pseudomonas aeruginosa quorum-sensing regulator VqsR." Journal of bacteriology.. 2007 Jun; 189(12):4367-74. Epub 2007 Apr 20.
2007 Jan
Wagner VE, Li LL, Isabella VM, Iglewski BH. "Analysis of the hierarchy of quorum-sensing regulation in Pseudomonas aeruginosa." Analytical and bioanalytical chemistry. 2007 Jan; 387(2):469-79. Epub 2006 Dec 01.
2006 Nov 28
Matsui H, Wagner VE, Hill DB, Schwab UE, Rogers TD, Button B, Taylor RM, Superfine R, Rubinstein M, Iglewski BH, Boucher RC. "A physical linkage between cystic fibrosis airway surface dehydration and Pseudomonas aeruginosa biofilms." Proceedings of the National Academy of Sciences of the United States of America.. 2006 Nov 28; 103(48):18131-6. Epub 2006 Nov 20.
2006 Feb
Wagner VE, Frelinger JG, Barth RK, Iglewski BH. "Quorum sensing: dynamic response of Pseudomonas aeruginosa to external signals." Trends in microbiology.. 2006 Feb; 14(2):55-8. Epub 2006 Jan 06.
2006
Filatrault, M.J., Picardo, K.F., Ngai, H., Passador, L. and Iglewski, B.H. "Identification of Pseudomonas aeruginosa Genes Involved in Virulence and anaerobic Growth. Infect. and Immun. 74, 4237-4245, 2006." Infect. and Immun.. 2006; .
2005 Jun
Filiatrault MJ, Wagner VE, Bushnell D, Haidaris CG, Iglewski BH, Passador L. "Effect of anaerobiosis and nitrate on gene expression in Pseudomonas aeruginosa." Infection and immunity.. 2005 Jun; 73(6):3764-72.
2005
Imamura Y, Higashiyama Y, Tomono K, Izumikawa K, Yanagihara K, Ohno H, Miyazaki Y, Hirakata Y, Mizuta Y, Kadota J, Iglewski BH, Kohno S. "Azithromycin Exhibits Bactericidal Effects on Pseudomonas aeruginosa through Interaction with the Outer Membrane. Antimicrob Agents Chemother. 2005 Apr;49(4):1377-80." Antimicrob Agents Chemother.. 2005; .
2005
Gillis, R.J. ,White,K.G., Choi,K-H., Wagner, W.E., Schwietzer, H.P.,and Iglewski, B.H. "Molecular Basis of Azithromycin-resistnat Pseudomonas aeruginosa Biofilms. Antimicrobial. Agents and Chemo. In press, Sept 2005." Agents and Chemo. 2005; .
2004
Wagner VE, Gillis RJ, Iglewski BH. "Transcriptome analysis of quorum-sensing regulation and virulence factor expression in Pseudomonas aeruginosa." Vaccine.. 2004 22 Suppl 1:S15-20.
2004
Gillis RJ, Iglewski BH. "Azithromycin retards Pseudomonas aeruginosa biofilm formation." Journal of clinical microbiology.. 2004 42(12):5842-5.
2003 Nov
Smith RS, Iglewski BH. "Pseudomonas aeruginosa quorum sensing as a potential antimicrobial target." The Journal of clinical investigation.. 2003 Nov; 112(10):1460-5.
2003 Apr
Wagner VE, Bushnell D, Passador L, Brooks AI, Iglewski BH. "Microarray analysis of Pseudomonas aeruginosa quorum-sensing regulons: effects of growth phase and environment." Journal of bacteriology.. 2003 Apr; 185(7):2080-95.
2003 Feb
Smith RS, Iglewski BH. "P. aeruginosa quorum-sensing systems and virulence." Current opinion in microbiology. 2003 Feb; 6(1):56-60.
2003
Lamb, J.R., Patel, H., Montiminy, T., Wagner, V.E., and Iglewski, B.H. "Functional domains of the Rh1R transcriptional regulator of Pseudomonas aeruginosa. J. Bacteriol. 185:7129-7139, 2003." J. Bacteriol.. 2003; .
2002 Oct
Yoon SS, Hennigan RF, Hilliard GM, Ochsner UA, Parvatiyar K, Kamani MC, Allen HL, DeKievit TR, Gardner PR, Schwab U, Rowe JJ, Iglewski BH, McDermott TR, Mason RP, Wozniak DJ, Hancock RE, Parsek MR, Noah TL, Boucher RC, Hassett DJ. "Pseudomonas aeruginosa anaerobic respiration in biofilms: relationships to cystic fibrosis pathogenesis." Developmental cell.. 2002 Oct; 3(4):593-603.
2002 Sep 1
Smith RS, Kelly R, Iglewski BH, Phipps RP. "The Pseudomonas autoinducer N-(3-oxododecanoyl) homoserine lactone induces cyclooxygenase-2 and prostaglandin E2 production in human lung fibroblasts: implications for inflammation." The Journal of immunology : official journal of the American Association of Immunologists.. 2002 Sep 1; 169(5):2636-42.
2002 Jun 18
de Kievit TR, Kakai Y, Register JK, Pesci EC, Iglewski BH. "Role of the Pseudomonas aeruginosa las and rhl quorum-sensing systems in rhlI regulation." FEMS microbiology letters. 2002 Jun 18; 212(1):101-6.
2001 Jul 1
Smith RS, Fedyk ER, Springer TA, Mukaida N, Iglewski BH, Phipps RP. "IL-8 production in human lung fibroblasts and epithelial cells activated by the Pseudomonas autoinducer N-3-oxododecanoyl homoserine lactone is transcriptionally regulated by NF-kappa B and activator protein-2." The Journal of immunology : official journal of the American Association of Immunologists.. 2001 Jul 1; 167(1):366-74.
2001 Jun
De Kievit TR, Parkins MD, Gillis RJ, Srikumar R, Ceri H, Poole K, Iglewski BH, Storey DG. "Multidrug efflux pumps: expression patterns and contribution to antibiotic resistance in Pseudomonas aeruginosa biofilms." Antimicrobial agents and chemotherapy.. 2001 Jun; 45(6):1761-70.
2001 Apr
De Kievit TR, Gillis R, Marx S, Brown C, Iglewski BH. "Quorum-sensing genes in Pseudomonas aeruginosa biofilms: their role and expression patterns." Applied and environmental microbiology. 2001 Apr; 67(4):1865-73.
2001 Mar
Branny P, Pearson JP, Pesci EC, Köhler T, Iglewski BH, Van Delden C. "Inhibition of quorum sensing by a Pseudomonas aeruginosa dksA homologue." Journal of bacteriology.. 2001 Mar; 183(5):1531-9.
2001 Mar
Bollinger N, Hassett DJ, Iglewski BH, Costerton JW, McDermott TR. "Gene expression in Pseudomonas aeruginosa: evidence of iron override effects on quorum sensing and biofilm-specific gene regulation." Journal of bacteriology.. 2001 Mar; 183(6):1990-6.
2000 Sep
de Kievit TR, Iglewski BH. "Bacterial quorum sensing in pathogenic relationships." Infection and immunity.. 2000 Sep; 68(9):4839-49.
2000 Aug 15
Rashid MH, Rumbaugh K, Passador L, Davies DG, Hamood AN, Iglewski BH, Kornberg A. "Polyphosphate kinase is essential for biofilm development, quorum sensing, and virulence of Pseudomonas aeruginosa." Proceedings of the National Academy of Sciences of the United States of America.. 2000 Aug 15; 97(17):9636-41.
2000 Jul
Pearson JP, Feldman M, Iglewski BH, Prince A. "Pseudomonas aeruginosa cell-to-cell signaling is required for virulence in a model of acute pulmonary infection." Infection and immunity.. 2000 Jul; 68(7):4331-4.
2000 May
McKnight SL, Iglewski BH, Pesci EC. "The Pseudomonas quinolone signal regulates rhl quorum sensing in Pseudomonas aeruginosa." Journal of bacteriology.. 2000 May; 182(10):2702-8.
1999 Nov
Rumbaugh KP, Griswold JA, Iglewski BH, Hamood AN. "Contribution of quorum sensing to the virulence of Pseudomonas aeruginosa in burn wound infections." Infection and immunity.. 1999 Nov; 67(11):5854-62.
1999 Sep 28
Pesci EC, Milbank JB, Pearson JP, McKnight S, Kende AS, Greenberg EP, Iglewski BH. "Quinolone signaling in the cell-to-cell communication system of Pseudomonas aeruginosa." Proceedings of the National Academy of Sciences of the United States of America.. 1999 Sep 28; 96(20):11229-34.
1999 Apr
de Kievit T, Seed PC, Nezezon J, Passador L, Iglewski BH. "RsaL, a novel repressor of virulence gene expression in Pseudomonas aeruginosa." Journal of bacteriology.. 1999 Apr; 181(7):2175-84.
1999 Mar
Glessner A, Smith RS, Iglewski BH, Robinson JB. "Roles of Pseudomonas aeruginosa las and rhl quorum-sensing systems in control of twitching motility." Journal of bacteriology.. 1999 Mar; 181(5):1623-9.
1999 Feb
Pearson JP, Van Delden C, Iglewski BH. "Active efflux and diffusion are involved in transport of Pseudomonas aeruginosa cell-to-cell signals." Journal of bacteriology.. 1999 Feb; 181(4):1203-10.
1999
Kline T, Bowman J, Iglewski BH, de Kievit T, Kakai Y, Passador L. "Novel synthetic analogs of the Pseudomonas autoinducer." Bioorganic & medicinal chemistry letters.. 1999 9(24):3447-52.
1999
De Kievit TR, Iglewski BH. "Quorum sensing, gene expression, and Pseudomonas biofilms." Methods in enzymology. 1999 310:117-28.
1999
Hassett DJ, Ma JF, Elkins JG, McDermott TR, Ochsner UA, West SE, Huang CT, Fredericks J, Burnett S, Stewart PS, McFeters G, Passador L, Iglewski BH. "Quorum sensing in Pseudomonas aeruginosa controls expression of catalase and superoxide dismutase genes and mediates biofilm susceptibility to hydrogen peroxide." Molecular microbiology. 1999 34(5):1082-93.
1998 Sep
Van Delden C, Pesci EC, Pearson JP, Iglewski BH. "Starvation selection restores elastase and rhamnolipid production in a Pseudomonas aeruginosa quorum-sensing mutant." Infection and immunity.. 1998 Sep; 66(9):4499-502.
1998 Apr 10
Davies DG, Parsek MR, Pearson JP, Iglewski BH, Costerton JW, Greenberg EP. "The involvement of cell-to-cell signals in the development of a bacterial biofilm." Science.. 1998 Apr 10; 280(5361):295-8.
1998
Van Delden C, Iglewski BH. "Cell-to-cell signaling and Pseudomonas aeruginosa infections." Emerging infectious diseases.. 1998 4(4):551-60.
1997 Sep
Pearson JP, Pesci EC, Iglewski BH. "Roles of Pseudomonas aeruginosa las and rhl quorum-sensing systems in control of elastase and rhamnolipid biosynthesis genes." Journal of bacteriology.. 1997 Sep; 179(18):5756-67.
1997 Aug
Preston MJ, Seed PC, Toder DS, Iglewski BH, Ohman DE, Gustin JK, Goldberg JB, Pier GB. "Contribution of proteases and LasR to the virulence of Pseudomonas aeruginosa during corneal infections." Infection and immunity.. 1997 Aug; 65(8):3086-90.
1997 Jun
Albus AM, Pesci EC, Runyen-Janecky LJ, West SE, Iglewski BH. "Vfr controls quorum sensing in Pseudomonas aeruginosa." Journal of bacteriology.. 1997 Jun; 179(12):3928-35.
1997 May
Pesci EC, Pearson JP, Seed PC, Iglewski BH. "Regulation of las and rhl quorum sensing in Pseudomonas aeruginosa." Journal of bacteriology.. 1997 May; 179(10):3127-32.
1997 Apr
Pesci EC, Iglewski BH. "The chain of command in Pseudomonas quorum sensing." Trends in microbiology.. 1997 Apr; 5(4):132-4; discussion 134-5.
1996 Oct
Passador L, Tucker KD, Guertin KR, Journet MP, Kende AS, Iglewski BH. "Functional analysis of the Pseudomonas aeruginosa autoinducer PAI." Journal of bacteriology.. 1996 Oct; 178(20):5995-6000.
1996 Feb
Rust L, Pesci EC, Iglewski BH. "Analysis of the Pseudomonas aeruginosa elastase (lasB) regulatory region." Journal of bacteriology.. 1996 Feb; 178(4):1134-40.
1996 Jan
Tang HB, DiMango E, Bryan R, Gambello M, Iglewski BH, Goldberg JB, Prince A. "Contribution of specific Pseudomonas aeruginosa virulence factors to pathogenesis of pneumonia in a neonatal mouse model of infection." Infection and immunity.. 1996 Jan; 64(1):37-43.
1995 Feb 28
Pearson JP, Passador L, Iglewski BH, Greenberg EP. "A second N-acylhomoserine lactone signal produced by Pseudomonas aeruginosa." Proceedings of the National Academy of Sciences of the United States of America.. 1995 Feb 28; 92(5):1490-4.
1995 Feb
Seed PC, Passador L, Iglewski BH. "Activation of the Pseudomonas aeruginosa lasI gene by LasR and the Pseudomonas autoinducer PAI: an autoinduction regulatory hierarchy." Journal of bacteriology.. 1995 Feb; 177(3):654-9.
1994 May
Gray KM, Passador L, Iglewski BH, Greenberg EP. "Interchangeability and specificity of components from the quorum-sensing regulatory systems of Vibrio fischeri and Pseudomonas aeruginosa." Journal of bacteriology.. 1994 May; 176(10):3076-80.
1994 Apr
Toder DS, Ferrell SJ, Nezezon JL, Rust L, Iglewski BH. "lasA and lasB genes of Pseudomonas aeruginosa: analysis of transcription and gene product activity." Infection and immunity.. 1994 Apr; 62(4):1320-7.
1994 Mar
West SE, Kaye SA, Hamood AN, Iglewski BH. "Characterization of Pseudomonas aeruginosa mutants that are deficient in exotoxin A synthesis and are altered in expression of regA, a positive regulator of exotoxin A." Infection and immunity.. 1994 Mar; 62(3):897-903.
1994 Jan 4
Pearson JP, Gray KM, Passador L, Tucker KD, Eberhard A, Iglewski BH, Greenberg EP. "Structure of the autoinducer required for expression of Pseudomonas aeruginosa virulence genes." Proceedings of the National Academy of Sciences of the United States of America.. 1994 Jan 4; 91(1):197-201.
1994
Rust L, Messing CR, Iglewski BH. "Elastase assays." Methods in enzymology. 1994 235:554-62.
1993 May 21
Passador L, Cook JM, Gambello MJ, Rust L, Iglewski BH. "Expression of Pseudomonas aeruginosa virulence genes requires cell-to-cell communication." Science.. 1993 May 21; 260(5111):1127-30.
1993 Apr
Gambello MJ, Kaye S, Iglewski BH. "LasR of Pseudomonas aeruginosa is a transcriptional activator of the alkaline protease gene (apr) and an enhancer of exotoxin A expression." Infection and immunity.. 1993 Apr; 61(4):1180-4.
1992 Mar
Wick MJ, Cook JM, Iglewski BH. "Structure-function analysis of exotoxin A proteins with mutations at histidine 426." Infection and immunity.. 1992 Mar; 60(3):1128-39.
1992 Feb
Hamood AN, Ohman DE, West SE, Iglewski BH. "Isolation and characterization of toxin A excretion-deficient mutants of Pseudomonas aeruginosa PAO1." Infection and immunity.. 1992 Feb; 60(2):510-7.
1991 Oct
Frank DW, Iglewski BH. "Cloning and sequence analysis of a trans-regulatory locus required for exoenzyme S synthesis in Pseudomonas aeruginosa." Journal of bacteriology.. 1991 Oct; 173(20):6460-8.
1991 Oct
Storey DG, Raivio TL, Frank DW, Wick MJ, Kaye S, Iglewski BH. "Effect of regB on expression from the P1 and P2 promoters of the Pseudomonas aeruginosa regAB operon." Journal of bacteriology.. 1991 Oct; 173(19):6088-94.
1991 Aug
Toder DS, Gambello MJ, Iglewski BH. "Pseudomonas aeruginosa LasA: a second elastase under the transcriptional control of lasR." Molecular microbiology. 1991 Aug; 5(8):2003-10.
1991 May
Gambello MJ, Iglewski BH. "Cloning and characterization of the Pseudomonas aeruginosa lasR gene, a transcriptional activator of elastase expression." Journal of bacteriology.. 1991 May; 173(9):3000-9.
1990 Oct
Olson JC, Hamood AN, Vincent TS, Beachey EH, Iglewski BH. "Identification of functional epitopes of Pseudomonas aeruginosa exotoxin A using synthetic peptides and subclone products." Molecular immunology.. 1990 Oct; 27(10):981-93.
1990 May
Hamood AN, Wick MJ, Iglewski BH. "Secretion of toxin A from Pseudomonas aeruginosa PAO1, PAK, and PA103 by Escherichia coli." Infection and immunity.. 1990 May; 58(5):1133-40.
1990 Apr
Wick MJ, Hamood AN, Iglewski BH. "Analysis of the structure-function relationship of Pseudomonas aeruginosa exotoxin A." Molecular microbiology. 1990 Apr; 4(4):527-35.
1990 Mar
Wick MJ, Frank DW, Storey DG, Iglewski BH. "Identification of regB, a gene required for optimal exotoxin A yields in Pseudomonas aeruginosa." Molecular microbiology. 1990 Mar; 4(3):489-97.
1990 Mar
Storey DG, Frank DW, Farinha MA, Kropinski AM, Iglewski BH. "Multiple promoters control the regulation of the Pseudomonas aeruginosa regA gene." Molecular microbiology. 1990 Mar; 4(3):499-503.
1990 Feb
Hamood AN, Iglewski BH. "Expression of the Pseudomonas aeruginosa toxA positive regulatory gene (regA) in Escherichia coli." Journal of bacteriology.. 1990 Feb; 172(2):589-94.
1990
Wick MJ, Frank DW, Storey DG, Iglewski BH. "Structure, function, and regulation of Pseudomonas aeruginosa exotoxin A." Annual review of microbiology. 1990 44:335-63.
1990
Mohr CD, Rust L, Albus AM, Iglewski BH, Deretic V. "Expression patterns of genes encoding elastase and controlling mucoidy: co-ordinate regulation of two virulence factors in Pseudomonas aeruginosa isolates from cystic fibrosis." Molecular microbiology. 1990 4(12):2103-10.
1989 Oct
Frank DW, Storey DG, Hindahl MS, Iglewski BH. "Differential regulation by iron of regA and toxA transcript accumulation in Pseudomonas aeruginosa." Journal of bacteriology.. 1989 Oct; 171(10):5304-13.
1989 Sep 29
Zimniak L, Dayn A, Iglewski BH. "Identification of RegA protein from Pseudomonas aeruginosa using anti-RegA antibody." Biochemical and biophysical research communications.. 1989 Sep 29; 163(3):1312-8.
1989 May 25
Coburn J, Wyatt RT, Iglewski BH, Gill DM. "Several GTP-binding proteins, including p21c-H-ras, are preferred substrates of Pseudomonas aeruginosa exoenzyme S." The Journal of biological chemistry.. 1989 May 25; 264(15):9004-8.
1989 Apr
Hamood AN, Olson JC, Vincent TS, Iglewski BH. "Regions of toxin A involved in toxin A excretion in Pseudomonas aeruginosa." Journal of bacteriology.. 1989 Apr; 171(4):1817-24.
1989 Mar
Coburn J, Dillon ST, Iglewski BH, Gill DM. "Exoenzyme S of Pseudomonas aeruginosa ADP-ribosylates the intermediate filament protein vimentin." Infection and immunity.. 1989 Mar; 57(3):996-8.
1989
Smith AW, Iglewski BH. "Transformation of Pseudomonas aeruginosa by electroporation." Nucleic acids research.. 1989 17(24):10509.
1988 Nov
Wick MJ, Iglewski BH. "Determination of the amino acid change responsible for the nontoxic, cross-reactive exotoxin A protein (CRM 66) of Pseudomonas aeruginosa PAO-PR1." Journal of bacteriology.. 1988 Nov; 170(11):5385-8.
1988 Oct 11
West SE, Iglewski BH. "Codon usage in Pseudomonas aeruginosa." Nucleic acids research.. 1988 Oct 11; 16(19):9323-35.
1988 Oct
Frank DW, Iglewski BH. "Kinetics of toxA and regA mRNA accumulation in Pseudomonas aeruginosa." Journal of bacteriology.. 1988 Oct; 170(10):4477-83.
1988 Sep
Bever RA, Iglewski BH. "Molecular characterization and nucleotide sequence of the Pseudomonas aeruginosa elastase structural gene." Journal of bacteriology.. 1988 Sep; 170(9):4309-14.
1988 Jun 24
Hindahl MS, Frank DW, Hamood A, Iglewski BH. "Characterization of a gene that regulates toxin A synthesis in Pseudomonas aeruginosa." Nucleic acids research.. 1988 Jun 24; 16(12):5699.
1988 Jun
Schad PA, Iglewski BH. "Nucleotide sequence and expression in Escherichia coli of the Pseudomonas aeruginosa lasA gene." Journal of bacteriology.. 1988 Jun; 170(6):2784-9.
1987 Jun
Schad PA, Bever RA, Nicas TI, Leduc F, Hanne LF, Iglewski BH. "Cloning and characterization of elastase genes from Pseudomonas aeruginosa." Journal of bacteriology.. 1987 Jun; 169(6):2691-6.
1987 Mar
Elsheikh LE, Kronevi T, Wretlind B, Abaas S, Iglewski BH. "Assessment of elastase as a Pseudomonas aeruginosa virulence factor in experimental lung infection in mink." Veterinary microbiology. 1987 Mar; 13(3):281-9.
1987 Feb
Hindahl MS, Iglewski BH. "Cloning and expression of a common Legionella outer membrane antigen in Escherichia coli." Microbial pathogenesis. 1987 Feb; 2(2):91-9.
1987
Hindahl MS, Frank DW, Iglewski BH. "Molecular studies of a positive regulator of toxin A synthesis in Pseudomonas aeruginosa." Antibiotics and chemotherapy. 1987 39:279-89.
1987
Parmely MJ, Horvat RT, Iglewski BH, Kanarek J, Furtado D, Van Enk R. "The antigenicity of a pulmonary pathogen defined by monoclonal T cells." Advances in experimental medicine and biology. 1987 216B:1043-51.
1986 Aug
Woodruff WA, Parr TR, Hancock RE, Hanne LF, Nicas TI, Iglewski BH. "Expression in Escherichia coli and function of Pseudomonas aeruginosa outer membrane porin protein F." Journal of bacteriology.. 1986 Aug; 167(2):473-9.
1986 May
Nicas TI, Iglewski BH. "Production of elastase and other exoproducts by environmental isolates of Pseudomonas aeruginosa." Journal of clinical microbiology.. 1986 May; 23(5):967-9.
1986 Mar
Dreyfus LA, Iglewski BH. "Purification and characterization of an extracellular protease of Legionella pneumophila." Infection and immunity.. 1986 Mar; 51(3):736-43.
1986 Jan
Hindahl MS, Iglewski BH. "Outer membrane proteins from Legionella pneumophila serogroups and other Legionella species." Infection and immunity.. 1986 Jan; 51(1):94-101.
1985 Oct
Nicas TI, Bradley J, Lochner JE, Iglewski BH. "The role of exoenzyme S in infections with Pseudomonas aeruginosa." The Journal of infectious diseases.. 1985 Oct; 152(4):716-21.
1985 Jun
Björklind A, Wretlind B, Möllegård I, Schad PA, Iglewski BH, Cox CD. "Genetic mapping and characterization of Pseudomonas aeruginosa mutants that hyperproduce exoproteins." Journal of bacteriology.. 1985 Jun; 162(3):1329-31.
1985 Apr
Nicas TI, Iglewski BH. "The contribution of exoproducts to virulence of Pseudomonas aeruginosa." Canadian journal of microbiology. 1985 Apr; 31(4):387-92.
1985 Apr
Nicas TI, Frank DW, Stenzel P, Lile JD, Iglewski BH. "Role of exoenzyme S in chronic Pseudomonas aeruginosa lung infections." European journal of clinical microbiology. 1985 Apr; 4(2):175-9.
1985 Jan
Lochner JE, Bigley RH, Iglewski BH. "Defective triggering of polymorphonuclear leukocyte oxidative metabolism by Legionella pneumophila toxin." The Journal of infectious diseases.. 1985 Jan; 151(1):42-6.
1985 Jan
Dreyfus LA, Iglewski BH. "Conjugation-mediated genetic exchange in Legionella pneumophila." Journal of bacteriology.. 1985 Jan; 161(1):80-4.
1985
Nicas TI, Iglewski BH. "Contribution of exoenzyme S to the virulence of Pseudomonas aeruginosa." Antibiotics and chemotherapy. 1985 36:40-8.
1985
Nicas TI, Iglewski BH. "Genetic approaches to study Pseudomonas aeruginosa protein antigens." Advances in experimental medicine and biology. 1985 185:223-32.
1984 Nov 1
Parmely MJ, Iglewski BH, Horvat RT. "Identification of the principal T lymphocyte-stimulating antigens of Pseudomonas aeruginosa." The Journal of experimental medicine.. 1984 Nov 1; 160(5):1338-49.
1984 Aug
Nicas TI, Iglewski BH. "Isolation and characterization of transposon-induced mutants of Pseudomonas aeruginosa deficient in production of exoenzyme S." Infection and immunity.. 1984 Aug; 45(2):470-4.
1984 Jul
Hindahl MS, Iglewski BH. "Isolation and characterization of the Legionella pneumophila outer membrane." Journal of bacteriology.. 1984 Jul; 159(1):107-13.
1984 Mar
Howe TR, Iglewski BH. "Isolation and characterization of alkaline protease-deficient mutants of Pseudomonas aeruginosa in vitro and in a mouse eye model." Infection and immunity.. 1984 Mar; 43(3):1058-63.
1983 Oct
Howe TR, Wretlind B, Iglewski BH. "Comparison of two methods of genetic exchange in determination of the genetic locus of the structural gene for Pseudomonas aeruginosa elastase." Journal of bacteriology.. 1983 Oct; 156(1):58-61.
1983 Apr
Hanne LF, Howe TR, Iglewski BH. "Locus of the Pseudomonas aeruginosa toxin A gene." Journal of bacteriology.. 1983 Apr; 154(1):383-6.
1983 Jan
Lochner JE, Friedman RL, Bigley RH, Iglewski BH. "Effect of oxygen-dependent antimicrobial systems on Legionella pneumophila." Infection and immunity.. 1983 Jan; 39(1):487-9.
1983 Jan
Blackwood LL, Stone RM, Iglewski BH, Pennington JE. "Evaluation of Pseudomonas aeruginosa exotoxin A and elastase as virulence factors in acute lung infection." Infection and immunity.. 1983 Jan; 39(1):198-201.
1983
Woods DE, Iglewski BH. "Toxins of Pseudomonas aeruginosa: new perspectives." Reviews of infectious diseases. 1983 5 Suppl 4:S715-22.
1983
Cryz SJ, Iglewski BH. "Toxoids of Pseudomonas aeruginosa toxin A: production by chemical and genetic means." Reviews of infectious diseases. 1983 5 Suppl 5:S992-7.
1982 Sep
Friedman RL, Lochner JE, Bigley RH, Iglewski BH. "The effects of Legionella pneumophila toxin on oxidative processes and bacterial killing of human polymorphonuclear leukocytes." The Journal of infectious diseases.. 1982 Sep; 146(3):328-34.
1982 Aug
Sokol PA, Cox CD, Iglewski BH. "Pseudomonas aeruginosa mutants altered in their sensitivity to the effect of iron on toxin A or elastase yields." Journal of bacteriology.. 1982 Aug; 151(2):783-7.
1982 Jul
Sadoff JC, Buck GA, Iglewski BH, Bjorn MJ, Groman NB. "Immunological cross-reactivity in the absence of DNA homology between Pseudomonas toxin A and diphtheria toxin." Infection and immunity.. 1982 Jul; 37(1):250-4.
1982 Jun
Woods DE, Cryz SJ, Friedman RL, Iglewski BH. "Contribution of toxin A and elastase to virulence of Pseudomonas aeruginosa in chronic lung infections of rats." Infection and immunity.. 1982 Jun; 36(3):1223-8.
1982 Feb
Woods DE, Sokol PA, Iglewski BH. "Modulatory effect of iron on the pathogenesis of Pseudomonas aeruginosa mouse corneal infections." Infection and immunity.. 1982 Feb; 35(2):461-4.
1982 Jan
Friedman RL, Iglewski BH, Roerdink F, Alving CR. "Suppression of cytotoxicity of diphtheria toxin by monoclonal antibodies against phosphatidylinositol phosphate." Biophysical journal.. 1982 Jan; 37(1):23-4.
1982
Hazlett LD, Iglewski BH, Berk RS. "Experimental Pseudomonas exotoxin A mediated ocular damage in mouse pups: microscopic observations." Ophthalmic research. 1982 14(6):401-8.
1981 Oct
Sokol PA, Iglewski BH, Hager TA, Sadoff JC, Cross AS, McManus A, Farber BF, Iglewski WJ. "Production of exoenzyme S by clinical isolates of Pseudomonas aeruginosa." Infection and immunity.. 1981 Oct; 34(1):147-53.
1981 Oct
Thompson MR, Miller RD, Iglewski BH. "In vitro production of an extracellular protease by Legionella pneumophila." Infection and immunity.. 1981 Oct; 34(1):299-302.
1981 Jul
Berk RS, Iglewski BH, Hazlett LD. "Age-related susceptibility of mice to ocular challenge with Pseudomonas aeruginosa exotoxin A." Infection and immunity.. 1981 Jul; 33(1):90-4.
1981 May
Cryz SJ, Friedman RL, Pavlovskis OR, Iglewski BH. "Effect of formalin toxoiding on Pseudomonas aeruginosa toxin A: biological, chemical, and immunochemical studies." Infection and immunity.. 1981 May; 32(2):759-68.
1981
Hazlett LD, Berk RS, Iglewski BH. "Microscopic characterization of ocular damage produced by Pseudomonas aeruginosa toxin A." Infection and immunity.. 1981 34(3):1025-35.
1980 Oct
Cross AS, Sadoff JC, Iglewski BH, Sokol PA. "Evidence for the role of toxin A in the pathogenesis of infection with Pseudomonas aeruginosa in humans." The Journal of infectious diseases.. 1980 Oct; 142(4):538-46.
1980 Oct
Ohman DE, Burns RP, Iglewski BH. "Corneal infections in mice with toxin A and elastase mutants of Pseudomonas aeruginosa." The Journal of infectious diseases.. 1980 Oct; 142(4):547-55.
1980 Jul
Cryz SJ, Iglewski BH. "Production of alkaline protease by Pseudomonas aeruginosa." Journal of clinical microbiology.. 1980 Jul; 12(1):131-3.
1980 Jul
Friedman RL, Iglewski BH, Miller RD. "Identification of a cytotoxin produced by Legionella pneumophila." Infection and immunity.. 1980 Jul; 29(1):271-4.
1980 Jun
Ohman DE, Cryz SJ, Iglewski BH. "Isolation and characterization of Pseudomonas aeruginosa PAO mutant that produces altered elastase." Journal of bacteriology.. 1980 Jun; 142(3):836-42.
1980 Jun
Ohman DE, Sadoff JC, Iglewski BH. "Toxin A-deficient mutants of Pseudomonas aeruginosa PA103: isolation and characterization." Infection and immunity.. 1980 Jun; 28(3):899-908.
1980 Apr
Alving CR, Iglewski BH, Urban KA, Moss J, Richards RL, Sadoff JC. "Binding of diphtheria toxin to phospholipids in liposomes." Proceedings of the National Academy of Sciences of the United States of America.. 1980 Apr; 77(4):1986-90.
1980
Cryz SJ, Friedman RL, Iglewski BH. "Isolation and characterization of a Pseudomonas aeruginosa mutant producing a nontoxic, immunologically crossreactive toxin A protein." Proceedings of the National Academy of Sciences of the United States of America.. 1980 77(12):7199-203.
1979 Jul
Brodsky WA, Sadoff JC, Durham JH, Ehrenspeck G, Schachner M, Iglewski BH. "Effects of pseudomonas toxin A, diphtheria toxin, and cholera toxin on electrical characteristics of turtle bladder." Proceedings of the National Academy of Sciences of the United States of America.. 1979 Jul; 76(7):3562-6.
1979 Jun
Bjorn MJ, Pavlovskis OR, Thompson MR, Iglewski BH. "Production of exoenzyme S during Pseudomonas aeruginosa infections of burned mice." Infection and immunity.. 1979 Jun; 24(3):837-42.
1979 Apr
Bjorn MJ, Sokol PA, Iglewski BH. "Influence of iron on yields of extracellular products in Pseudomonas aeruginosa cultures." Journal of bacteriology.. 1979 Apr; 138(1):193-200.
1979 Apr
Sokol PA, Ohman DE, Iglewski BH. "A more sensitive plate assay for detection of protease production by Pseudomanas aeruginosa." Journal of clinical microbiology.. 1979 Apr; 9(4):538-40.
1979
Iglewski BH, Sadoff JC. "Toxin inhibitors of protein synthesis: production, purification, and assay of Pseudomonas aeruginosa toxin A." Methods in enzymology. 1979 60:780-93.
1978 Oct
Vasil ML, Iglewski BH. "Comparative toxicities of diphtherial toxin and Pseudomonas aeruginosa exotoxin A: evidence for different cell receptors." Journal of general microbiology. 1978 Oct; 108(2):333-7.
1978 Jul
Iglewski BH, Sadoff J, Bjorn MJ, Maxwell ES. "Pseudomonas aeruginosa exoenzyme S: an adenosine diphosphate ribosyltransferase distinct from toxin A." Proceedings of the National Academy of Sciences of the United States of America.. 1978 Jul; 75(7):3211-5.
1978 Mar
Bjorn MJ, Iglewski BH, Ives SK, Sadoff JC, Vasil ML. "Effect of iron on yields of exotoxin A in cultures of Pseudomonas aeruginosa PA-103." Infection and immunity.. 1978 Mar; 19(3):785-91.
1978 Jan
Pavlovskis OR, Iglewski BH, Pollack M. "Mechanism of action of Pseudomonas aeruginosa exotoxin A in experimental mouse infections: adenosine diphosphate ribosylation of elongation factor 2." Infection and immunity.. 1978 Jan; 19(1):29-33.
1977 Apr
Bjorn MJ, Vasil ML, Sadoff JC, Iglewski BH. "Incidence of exotoxin production by Pseudomonas species." Infection and immunity.. 1977 Apr; 16(1):362-6.
1977 Apr
Vasil ML, Kabat D, Iglewski BH. "Structure-activity relationships of an exotoxin of Pseudomonas aeruginosa." Infection and immunity.. 1977 Apr; 16(1):353-61.
1977 Jan
Iglewski BH, Liu PV, Kabat D. "Mechanism of action of Pseudomonas aeruginosa exotoxin Aiadenosine diphosphate-ribosylation of mammalian elongation factor 2 in vitro and in vivo." Infection and immunity.. 1977 Jan; 15(1):138-44.
1977 Jan
Iglewski BH, Burns RP, Gipson IK. "Pathogenesis of corneal damage from pseudomonas exotoxin A." Investigative ophthalmology & visual science.. 1977 Jan; 16(1):73-6.
1977
Pavlovskis OR, Pollack M, Callahan LT, Iglewski BH. "Passive protection by antitoxin in experimental Pseudomonas aeruginosa burn infections." Infection and immunity.. 1977 18(3):596-602.
1976 Aug
Morse SA, Vaughan P, Johnson D, Iglewski BH. "Inhibition of Neisseria gonorrhoeae by a bacteriocin from Pseudomonas aeruginosa." Antimicrobial agents and chemotherapy.. 1976 Aug; 10(2):354-62.
1976 Jul
Rittenberg MB, Pinney CT, Iglewski BH. "Antigenic relationships on the diphtheria toxin molecule: antitoxin versus antitoxoid." Infection and immunity.. 1976 Jul; 14(1):122-8.
1976 May
Vasil ML, Liu PV, Iglewski BH. "Temperature-dependent inactivating factor of Pseudomonas aeruginosa exotoxin A." Infection and immunity.. 1976 May; 13(5):1467-72.
1975 Jun
Iglewski BH, Kabat D. "NAD-dependent inhibition of protein synthesis by Pseudomonas aeruginosa toxin,." Proceedings of the National Academy of Sciences of the United States of America.. 1975 Jun; 72(6):2284-8.
1975 May
Iglewski BH, Rittenberg MB, Iglewski WJ. "Preferential inhibition of growth and protein synthesis in Rous sarcoma virus transformed cells by diphtheria toxin." Virology.. 1975 May; 65(1):272-5.
1974 Jul
Iglewski BH, Rittenberg MB. "Selective toxicity of diphtheria toxin for malignant cells." Proceedings of the National Academy of Sciences of the United States of America.. 1974 Jul; 71(7):2707-10.
1974 Jan 23
Lightfoot HN, Iglewski BH. "Synthesis of diphtheria toxin in E. coli cell-free lysate." Biochemical and biophysical research communications.. 1974 Jan 23; 56(2):351-7.
1972 Nov 1
Elwell LP, Iglewski BH. "Diphtheria toxin: evidence for presence of fragment B in corynebacteriophage." Biochemical and biophysical research communications.. 1972 Nov 1; 49(3):609-14.

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