James R. Campbell, M.D., M.P.H.

James R. Campbell, M.D., M.P.H.

Contact Information

Rochester General Hospital
1425 Portland Avenue
Rochester, NY 14621

Office: (585) 922-5658
Fax: (585) 922-3929

Research Bio

Dr. Campbell's research focuses on childhood lead toxicity, with two major projects underway:
Lead exposure and bone development: Basic-science research and our own preliminary studies show that lead exposure can adversely affect the development of bone density. The current study, being conducted with the Department of Orthopedics, is investigating whether lead exposure is a risk factor for the development of osteoporosis. We are conducting cross-sectional studies on 8-9 year old children, 18-19 year-old adolescents and 60-65 year old adults. All subjects are having their bone density measured by DEXA, and their bone lead level measured by KXRF; the URMC is one of the few institutions in the country to have KXRF technology. This project is funded by the National Institute of Environmental Health Sciences of the NIH.



Lead exposure and humoral immunity: Basic-science research studies show that lead exposure can adversely affect the development of antibodies after an infection or immunization. The current study, being conducted with the Cancer Institute, is investigating whether lead exposure is associated with lowered humoral response after vaccination with the HPV vaccine. We will enroll 11-12 year old girls with a broad-range of past lead exposure based on blood lead levels obtained at ages 1-3 years. All will have blood drawn before the vaccine is administered and at 1, 2, and 6 months after the first vaccine. This project is funded by the National Institute of Environmental Health Sciences at NIH.

Awards & Honors (Local)

Member, Environmental Health Sciences Center Department of Environmental Medicine | University of Rochester | Rochester, NY 2008
Rochester Academy of Medicine Library Award for the best paper in Medical History | Rochester, NY 1990
Award for Academic Excellence in Pathology | Medical College Ohio | Toledo, OH 1985
International Physicians of Northwest Ohio Scholarship | Medical College Ohio | Toledo, OH 1984

Recent Journal Articles

Showing the 5 most recent journal articles. 17 available »

2011 Jan
Eisenberg KW, van Wijngaarden E, Fisher SG, Korfmacher KS, Campbell JR, Fernandez ID, Cochran J, Geltman PL. "Blood lead levels of refugee children resettled in Massachusetts, 2000 to 2007." American journal of public health. 2011 Jan; 101(1):48-54. Epub 2010 Nov 18.
2011
Campbell JR. "Noninferiority trials". AAP Grand Rounds. 2011; 26(27).
2009 Jul
van Wijngaarden E, Campbell JR, Cory-Slechta DA. "Bone lead levels are associated with measures of memory impairment in older adults." Neurotoxicology. 2009 Jul; 30(4):572-80. Epub 2009 May 27.
2007 Jul
Campbell JR, Auinger P. "The association between blood lead levels and osteoporosis among adults--results from the third national health and nutrition examination survey (NHANES III)." Environmental health perspectives. 2007 Jul; 115(7):1018-22.
2004 Aug
Campbell JR, Rosier RN, Novotny L, Puzas JE. "The association between environmental lead exposure and bone density in children". Env Hlth Persp. 2004; 112((11)): 1200-1203. Link

Current Appointments

Associate Professor - Department of Pediatrics, General Pediatrics (SMD) - Primary

Specialties

Pediatrics - American Board of Pediatrics

Education

MPH | Public Health | University of Rochester School of Medicine and Dentistry1993
MD | Medicine | Medical College Ohio1985
BS | Chemistry | University of Akron1980

Post-Doctoral Training & Residency

Fellowship in General Pediatrics at University of Rochester Medical Center07/01/1988 - 06/30/1991
Residency in Pediatrics at Rainbow Babies & Children s Hospital07/01/1986 - 06/30/1988
Internship in Pediatrics at Rainbow Babies & Children s Hospital07/01/1985 - 06/30/1986