Research Bio
Dr. Campbell's research focuses on childhood lead toxicity, with two major projects underway:
Lead exposure and bone development: Basic-science research and our own preliminary studies show that lead exposure can adversely affect the development of bone density. The current study, being conducted with the Department of Orthopedics, is investigating whether lead exposure is a risk factor for the development of osteoporosis. We are conducting cross-sectional studies on 8-9 year old children, 18-19 year-old adolescents and 60-65 year old adults. All subjects are having their bone density measured by DEXA, and their bone lead level measured by KXRF; the URMC is one of the few institutions in the country to have KXRF technology. This project is funded by the National Institute of Environmental Health Sciences of the NIH.
Lead exposure and humoral immunity: Basic-science research studies show that lead exposure can adversely affect the development of antibodies after an infection or immunization. The current study, being conducted with the Cancer Institute, is investigating whether lead exposure is associated with lowered humoral response after vaccination with the HPV vaccine. We will enroll 11-12 year old girls with a broad-range of past lead exposure based on blood lead levels obtained at ages 1-3 years. All will have blood drawn before the vaccine is administered and at 1, 2, and 6 months after the first vaccine. This project is funded by the National Institute of Environmental Health Sciences at NIH.
2004 Aug
Campbell JR, Rosier RN, Novotny L, Puzas JE. "The association between environmental lead exposure and bone density in children". Env Hlth Persp. 2004; 112((11)): 1200-1203. |
2001
Campbell JR, Toribara TY. "Hair-root lead to screen for lead toxicity". J Trace Elem Exp Med. 2001; 14: 69-72. |
2000 Nov
Campbell J, Moss M, Raubertas R. "The association between caries and childhood lead exposure". Env Hlth Persp. 2000; 108((11)): 1099-1102. |
1999 Jun
Campbell JR, Schaffer SJ. "Predicting the outcome of the CaNa2EDTA challenge test in children with moderately elevated blood lead levels". Env Hlth Persp. 1999; 107((6)): 437-440. |
1998 Feb
Schaffer SJ, Campbell JR, Szilagyi PG, Weitzman M. "Lead screening practices of pediatric residents." Archives of pediatrics & adolescent medicine. 1998 Feb 0; 152(2):185-9. |
