Regis J. O'Keefe, M.D., Ph.D.

Regis J. O'Keefe, M.D., Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 665
Rochester, NY 14642

Appointment: (585) 275-5321

  • Accepting New Patients Accepting New Patients
  • Admits to Strong Memorial Hospital Admits to Strong Memorial Hospital
  • Admits to Highland Hospital Admits to Highland Hospital

Patient Care Bio

Dr. O'Keefe is an orthopaedic oncologist, or a surgeon who focuses his practice on people with tumors of bone, joints, and soft tissue. He also cares for patients with fragility fractures from osteoporosis, osteopenia, osteogenesis imperfecta, and low vitamin D. Because many patients entering Dr. O'Keefe's practice are experiencing the most challenging time of their life, his treatment goal is to provide the best quality of life possible and instill confidence in his patients that they are getting the best care possible.



Dr. O'Keefe earned his medical degree from Harvard Medical School and completed a residency in orthopaedic surgery at URMC. He then completed the Massachusetts General Hospital fellowship in orthopaedic oncology. Soon, he realized he could help more people if the causes of diseases of the skeleton were better understood. He earned a PhD in biochemistry at URMC while conducting research.

Dr. O'Keefe, a national leader in the field of orthopaedics, is the Chair of URMC's Department of Orthopaedics and Rehabilitation. He also serves as the Director of the Center for Musculoskeletal Research at URMC, a team of nearly 70 physicians, biomedical scientists, and graduate and post-doctoral students. This team remains the top orthopaedics research lab in the United States since 2006.

Awards & Honors (Local)

Best Doctors in America for Cancerous Tumor Surgery 2009
Fifth Annual Dr. Marvin J Hoffman Award in the Area of Faculty Mentoring to Medical Students, Awarded at the Annual Hoffman Awards Ceremony, 2003
Dean's Endowed Chair, Professor of Orthopaedics and Oncology, University of Rochester School of Medicine. 2000
American Orthopaedic Association ABC Traveling Fellowship, 1999
Dean's Endowed Chair, Associate Professor of Orthopaedics, University of Rochester School of Medicine. 1998
The Dane and Mary Louise Miller Endowed Research Grant, Orthopaedic Research and Educational Foundation, 1997
Kappa Delta Award, Orthopaedic Research & Education Foundation. 1995
AOA Resident Traveling Research Award, "Differential expression of transforming growth factor-ß receptors and biological effects in maturationally distinct subpopulations of growth plate chondrocytes. 1988

Patents

Repair and Regeneration of Articular Cartilage, and the Repair and Regeneration of Fibrocartilaginous Tissues

United States Serial NO.: 13/124,002
Filed Date: October 13, 2009
Title: Protecting and Repairing Cartilage and Musculoskeletal Soft Tissues
Invented by: Randy Rosier, Michael Zuscik, Erik Sampson, Susan Bukata, J. Edward Puzas, Regis O'Keefe, Hani Awad
Repair and Regeneration of Articular Cartilage, and the Repair and Regeneration of Fibrocartilaginous Tissues

United States Serial NO.: 13/971,366
Filed Date: August 20, 2013
Title: Protecting and Repairing Cartilage and Musculoskeletal Soft Tissues
Invented by: Randy Rosier, Michael Zuscik, Erik Sampson, Susan Bukata, J. Edward Puzas, Regis O'Keefe, Hani Awad
EP-1: Enhanced Osteoblast Differentiation and Accelerated Fracture Repair

United States Serial NO.: 13/582,927
Filed Date: March 4, 2011
Title: EP1 Inhibition
Invented by: Regis O'Keefe, Minjie Zhang

Current Appointments

Associate Dean for Clinical Affairs - Department of Dean's Office, SMD (SMD)
Chair - Department of Orthopaedics (SMD) - Primary Administrative
Marjorie Strong Wehle Professor in Orthopaedics - Department of Orthopaedics (SMD)
Professor - Department of Orthopaedics (SMD) - Primary
Professor - Department of Biochemistry and Biophysics (SMD)

Specialties

Orthopaedic Surgery - American Board of Orthopedic Surgery

Education

PhD | Biochemistry | University of Rochester School of Medicine and Dentistry2000
MD | Medicine | Harvard Medical School1985
BA | Philosophy | Yale University1981

Post-Doctoral Training & Residency

Fellowship in Orthopaedic Oncology at Massachusetts General Hospital07/01/1992 - 06/01/1993
Residency in Orthopaedics at Strong Memorial Hospital- GME Office07/01/1988 - 06/01/1992
Internship in Surgery/Orthopaedics at Deaconess Hospital09/01/1985 - 06/30/1986