Regis J. O'Keefe, M.D., Ph.D.

Regis J. O'Keefe, M.D., Ph.D.

Contact Information

Department of Orthopaedic Surgery
Washington University School of Medicine
Campus Box 8233, 660 South Euclid Avenue
St. Louis, Missouri 63110

Fax: (585) 756-4721
Administrative: (585) 275-3100
Office: (585) 275-5167
Administrative: (585) 273-1261

Lab Information

The Center for Musculoskeletal Research houses nearly 70 MD and PhD researchers and graduate and post-doctoral students. This team has been the top orthopaedics lab in the United States since 2006.

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Bio

The biographical information for Regis J. O'Keefe, M.D., Ph.D. is not currently available.

Awards & Honors (Local)

Best Doctors in America for Cancerous Tumor Surgery 2009
Fifth Annual Dr. Marvin J Hoffman Award in the Area of Faculty Mentoring to Medical Students, Awarded at the Annual Hoffman Awards Ceremony, 2003
Dean's Endowed Chair, Professor of Orthopaedics and Oncology, University of Rochester School of Medicine. 2000
American Orthopaedic Association ABC Traveling Fellowship, 1999
Dean's Endowed Chair, Associate Professor of Orthopaedics, University of Rochester School of Medicine. 1998
The Dane and Mary Louise Miller Endowed Research Grant, Orthopaedic Research and Educational Foundation, 1997
Kappa Delta Award, Orthopaedic Research & Education Foundation. 1995
AOA Resident Traveling Research Award, "Differential expression of transforming growth factor-ß receptors and biological effects in maturationally distinct subpopulations of growth plate chondrocytes. 1988

Patents

Repair and Regeneration of Articular Cartilage, and the Repair and Regeneration of Fibrocartilaginous Tissues

United States Serial NO.: 13/124,002
Filed Date: October 13, 2009
Title: Protecting and Repairing Cartilage and Musculoskeletal Soft Tissues
Invented by: Randy Rosier, Michael Zuscik, Erik Sampson, Susan Bukata, J. Edward Puzas, Regis O'Keefe, Hani Awad
Repair and Regeneration of Articular Cartilage, and the Repair and Regeneration of Fibrocartilaginous Tissues

United States Serial NO.: 13/971,366
Filed Date: August 20, 2013
Title: Protecting and Repairing Cartilage and Musculoskeletal Soft Tissues
Invented by: Randy Rosier, Michael Zuscik, Erik Sampson, Susan Bukata, J. Edward Puzas, Regis O'Keefe, Hani Awad
EP-1: Enhanced Osteoblast Differentiation and Accelerated Fracture Repair

United States Serial NO.: 13/582,927
Filed Date: March 4, 2011
Title: EP1 Inhibition
Invented by: Regis O'Keefe, Minjie Zhang

Recent Journal Articles

Showing the 5 most recent journal articles. 287 available »

2014
Shane E, Ebeling PR, Abrahamsen B, Adler RA, Brown TD, Cheung AM, Cosman F, Curtis JR, Dell R, Dempster DW, Einhorn TA, Genant HK, Geusens P, Klaushofer K, Lane JM, McKiernan F, McKinney R, Ng A, Nieves J, O'Keefe R, Papapoulos S, Howe TS, van der Meulen MC, Weinstein RS, Whyte MP. "Atypical subtrochanteric and diaphyseal femoral fractures: Second report of a task force of the American society for bone and mineral research." Journal of Bone and Mineral Research. 2014; .
2013
Dhillon RS, Xie C, Tyler W, Calvi LM, Awad HA, Zuscik MJ, O'Keefe RJ, Schwarz EM. "PTH-enhanced structural allograft healing is associated with decreased angiopoietin-2-mediated arteriogenesis, mast cell accumulation, and fibrosis." Journal of Bone and Mineral Research. 2013; 28(3): 586-97.
2013
Mirando AJ, Liu Z, Moore T, Lang A, Kohn A, Osinski AM, O'Keefe RJ, Mooney RA, Zuscik MJ, Hilton MJ. "RBP-J?-Dependent Notch Signaling Is Required for Murine Articular Cartilage and Joint Maintenance." Arthritis Rheumatology. 2013; 65(10): 2623-33.
2013
Bonewald LF, Kiel DP, Clemens TL, Esser K, Orwoll ES, O'Keefe RJ, Fielding RA. "Forum on bone and skeletal muscle interactions: summary of the proceedings of an ASBMR workshop." Journal of Bone and Mineral Research. 2013; 28(9): 1857-65.
2013
Shah K, Majeed Z, Jonason J, O'Keefe RJ. "The role of muscle in bone repair: the cells, signals, and tissue responses to injury." Current Osteoporosis Reports. 2013; 11(2): 130-5.

Current Appointments

Adjunct Professor - Department of Orthopaedics, Center for Musculoskeletal Research (SMD)

Specialties

Orthopaedic Surgery - American Board of Orthopedic Surgery

Education

PhD | Biochemistry | University of Rochester School of Medicine and Dentistry2000
MD | Medicine | Harvard Medical School1985
BA | Philosophy | Yale University1981

Post-Doctoral Training & Residency

Massachusetts General Hospital Fellowship in Orthopaedic Oncology 1993
The University of Rochester Medical Center, Rochester, NY Resident in Orthopaedics 1992
University of Rochester School of Medicine and Dentistry, Instructor and Fellow in Research Orthopaedic Research Laboratories 1988
University of Rochester School of Medicine and Dentistry, Instructor and Fellow in Research, Endocrinology Training Grant 1988
New England Deaconess Hospital Harvard Medical School Surgical Internship 1986