Regis J. O'Keefe, M.D., Ph.D.

Regis J. O'Keefe, M.D., Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 665
Rochester, NY 14642

Fax: (585) 756-4721
Administrative: (585) 275-3100
Office: (585) 275-5167
Administrative: (585) 273-1261

Lab Description

The Center for Musculoskeletal Research houses nearly 70 MD and PhD researchers and graduate and post-doctoral students. This team has been the top orthopaedics lab in the United States since 2006.

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Bio

Dr. O'Keefe's biographical information is not currently available.

Awards & Honors

Best Doctors in America for Cancerous Tumor Surgery 2009
Fifth Annual Dr. Marvin J Hoffman Award in the Area of Faculty Mentoring to Medical Students, Awarded at the Annual Hoffman Awards Ceremony, 2003
Dean's Endowed Chair, Professor of Orthopaedics and Oncology, University of Rochester School of Medicine. 2000
American Orthopaedic Association ABC Traveling Fellowship, 1999
Dean's Endowed Chair, Associate Professor of Orthopaedics, University of Rochester School of Medicine. 1998
The Dane and Mary Louise Miller Endowed Research Grant, Orthopaedic Research and Educational Foundation, 1997
Kappa Delta Award, Orthopaedic Research & Education Foundation. 1995
AOA Resident Traveling Research Award, "Differential expression of transforming growth factor-ß receptors and biological effects in maturationally distinct subpopulations of growth plate chondrocytes. 1988

Recent Journal Articles

Showing the 5 most recent journal articles. 277 available »

2012
Xie C, Schwarz EM, Sampson ER, Dhillon RS, Li D, O'Keefe RJ, Tyler W. "Unique angiogenic and vasculogenic properties of renal cell carcinoma in a xenograft model of bone metastasis are associated with high levels of vegf-a and decreased ang-1 expression." Journal of Orthopaedic Research. 2012; 30(2): 325-33.
2012
Kohn A, Dong Y, Mirando AJ, Jesse AM, Honjo T, Zuscik MJ, O'Keefe RJ, Hilton MJ. "Cartilage-specific RBPj?-dependent and -independent Notch signals regulate cartilage and bone development." Development. 2012; 139(6): 1198-212.
2012
Dao DY, Jonason JH, Zhang Y, Hsu W, Chen D, Hilton MJ, O'Keefe RJ. "Cartilage-specific ß-CATENIN signaling regulates chondrocyte maturation, generation of ossification centers, and perichondrial bone formation during skeletal development." Journal of Bone and Mineral Research. 2012; .
2012
Kim KO, Sampson ER, Maynard RD, O'Keefe RJ, Chen D, Drissi H, Rosier RN, Hilton MJ, Zuscik MJ. "Ski inhibits TGF-?/phospho-Smad3 signaling and accelerates hypertrophic differentiation in chondrocytes." Journal of Cellular Biochemistry. 2012; 113(6): 2156-66.
2012
Wang M, Tang D, Shu B, Wang B, Jin H, Hao S, Dresser KA, Shen J, Im HJ, Sampson ER, Rubery PT, Zuscik MJ, Schwarz EM, O'Keefe RJ, Wang Y, Chen D. "Conditional activation of ?-catenin signaling leads to severe defects in intervertebral disc tissue." Arthritis and Rheumatism. 2012; .

Current Appointments

Associate Dean for Clinical Affairs - Department of Dean's Office, SMD (SMD)
Chair - Department of Orthopaedics (SMD) - Primary Administrative
Marjorie Strong Wehle Professor in Orthopaedics - Department of Orthopaedics (SMD)
Professor - Department of Orthopaedics (SMD) - Primary
Professor - Department of Biochemistry and Biophysics (SMD)
Professor - Department of Environmental Medicine (SMD)

Specialties

Orthopaedic Surgery - American Board of Orthopedic Surgery

Education

PhD | Biochemistry | University of Rochester School of Medicine and Dentistry2000
MD | Medicine | Harvard Medical School1985
BA | Philosophy | Yale University1981

Post-Doctoral Training & Residency

Fellowship in Orthopaedic Oncology at Massachusetts General Hospital07/01/1992 - 06/01/1993
Residency in Orthopaedics at Strong Memorial Hospital- GME Office07/01/1988 - 06/01/1992
Internship in Surgery/Orthopaedics at Deaconess Hospital09/01/1985 - 06/30/1986