Mark J. Utell, M.D.

Mark J. Utell, M.D.

Contact Information


Office: (585) 275-4161
Fax: (585) 273-1171

Journal Articles

Showing all 65 journal articles available.

2010
Stewart JC, Chalupa DC, Devlin RB, Frasier LM, Huang LS, Little EL, Lee SM, Phipps RP, Pietropaoli AP, Taubman MB, Utell MJ, Frampton MW. "Vascular effects of ultrafine particles in persons with type 2 diabetes." Environmental health perspectives. 2010 118(12):1692-8. Epub 2010 Sep 07.
2009 Feb
Zareba W, Couderc JP, Oberdörster G, Chalupa D, Cox C, Huang LS, Peters A, Utell MJ, Frampton MW. "ECG parameters and exposure to carbon ultrafine particles in young healthy subjects." Inhalation toxicology. 2009 Feb; 21(3):223-33.
2008 Mar
Shah AP, Pietropaoli AP, Frasier LM, Speers DM, Chalupa DC, Delehanty JM, Huang LS, Utell MJ, Frampton MW. "Effect of inhaled carbon ultrafine particles on reactive hyperemia in healthy human subjects." Environmental health perspectives. 2008 Mar; 116(3):375-80.
2007 May
Pietropaoli AP, Perillo IB, Perkins PT, Frasier LM, Speers DM, Frampton MW, Utell MJ, Hyde RW. "Smokers have reduced nitric oxide production by conducting airways but normal levels in the alveoli." Inhalation toxicology. 2007 May; 19(6-7):533-41.
2007 Jan
Elder A, Couderc JP, Gelein R, Eberly S, Cox C, Xia X, Zareba W, Hopke P, Watts W, Kittelson D, Frampton M, Utell M, Oberdörster G. "Effects of on-road highway aerosol exposures on autonomic responses in aged, spontaneously hypertensive rats." Inhalation toxicology. 2007 Jan; 19(1):1-12.
2006 Jan
Frampton MW, Stewart JC, Oberdörster G, Morrow PE, Chalupa D, Pietropaoli AP, Frasier LM, Speers DM, Cox C, Huang LS, Utell MJ. "Inhalation of ultrafine particles alters blood leukocyte expression of adhesion molecules in humans." Environmental health perspectives. 2006 Jan; 114(1):51-8.
2006
Utell MJ, Beckett WS. "Implications for occupational exposure to particulate matter." Clinics in occupational and environmental medicine. 2006 5(4):883-93.
2006
Stewart JC, Hyde RW, Boscia J, Chow MY, O'Mara RE, Perillo I, Pietropaoli A, Smith CJ, Torres A, Utell MJ, Frampton MW. "Changes in markers of epithelial permeability and inflammation in chronic smokers switching to a nonburning tobacco device (Eclipse)." Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. 2006 8(6):773-83.
2005 Jun
Barron BA, Beckett WS, Utell MJ. "Clinical activities in an academic hospital-based occupational medicine program." Journal of occupational and environmental medicine. 2005 Jun; 47(6):587-93.
2005 May 15
Beckett WS, Chalupa DF, Pauly-Brown A, Speers DM, Stewart JC, Frampton MW, Utell MJ, Huang LS, Cox C, Zareba W, Oberdörster G. "Comparing inhaled ultrafine versus fine zinc oxide particles in healthy adults: a human inhalation study." American journal of respiratory and critical care medicine. 2005 May 15; 171(10):1129-35. Epub 2005 Feb 25.
2004 Jun
Chalupa DC, Morrow PE, Oberdörster G, Utell MJ, Frampton MW. "Ultrafine particle deposition in subjects with asthma." Environmental health perspectives. 2004 Jun; 112(8):879-82.
2004
Elder A, Gelein R, Finkelstein J, Phipps R, Frampton M, Utell M, Kittelson DB, Watts WF, Hopke P, Jeong CH, Kim E, Liu W, Zhao W, Zhuo L, Vincent R, Kumarathasan P, Oberdörster G. "On-road exposure to highway aerosols. 2. Exposures of aged, compromised rats." Inhalation toxicology. 2004 16 Suppl 1:41-53.
2004
Pietropaoli AP, Frampton MW, Hyde RW, Morrow PE, Oberdörster G, Cox C, Speers DM, Frasier LM, Chalupa DC, Huang LS, Utell MJ. "Pulmonary function, diffusing capacity, and inflammation in healthy and asthmatic subjects exposed to ultrafine particles." Inhalation toxicology. 2004 16 Suppl 1:59-72.
2004
Frampton MW, Utell MJ, Zareba W, Oberdörster G, Cox C, Huang LS, Morrow PE, Lee FE, Chalupa D, Frasier LM, Speers DM, Stewart J. "Effects of exposure to ultrafine carbon particles in healthy subjects and subjects with asthma." Research report (Health Effects Institute). 2004 (126):1-47; discussion 49-63.
2003 May
Daigle CC, Chalupa DC, Gibb FR, Morrow PE, Oberdörster G, Utell MJ, Frampton MW. "Ultrafine particle deposition in humans during rest and exercise." Inhalation toxicology. 2003 May; 15(6):539-52.
2002 Jan
Frampton MW, Boscia J, Roberts NJ, Azadniv M, Torres A, Cox C, Morrow PE, Nichols J, Chalupa D, Frasier LM, Gibb FR, Speers DM, Tsai Y, Utell MJ. "Nitrogen dioxide exposure: effects on airway and blood cells." American journal of physiology. Lung cellular and molecular physiology. 2002 Jan; 282(1):L155-65.
2002
Zareba G, Gelein R, Morrow PE, Utell MJ. "Percutaneous absorption studies of octamethylcyclotetrasiloxane using the human skin/nude mouse model." Skin pharmacology and applied skin physiology. 2002 15(3):184-94.
2002
Utell MJ, Frampton MW, Zareba W, Devlin RB, Cascio WE. "Cardiovascular effects associated with air pollution: potential mechanisms and methods of testing." Inhalation toxicology. 2002 14(12):1231-47.
2001 Nov
Perillo IB, Hyde RW, Olszowka AJ, Pietropaoli AP, Frasier LM, Torres A, Perkins PT, Forster RE, Utell MJ, Frampton MW. "Chemiluminescent measurements of nitric oxide pulmonary diffusing capacity and alveolar production in humans." Journal of applied physiology. 2001 Nov; 91(5):1931-40.
2001 Jun
Voter KZ, Whitin JC, Torres A, Morrow PE, Cox C, Tsai Y, Utell MJ, Frampton MW. "Ozone exposure and the production of reactive oxygen species by bronchoalveolar cells in humans." Inhalation toxicology. 2001 Jun; 13(6):465-83.
2001 Jun
Azadniv M, Torres A, Boscia J, Speers DM, Frasier LM, Utell MJ, Frampton MW. "Neutrophils in lung inflammation: Which reactive oxygen species are being measured?" Inhalation toxicology. 2001 Jun; 13(6):485-95.
2000 Aug
Utell MJ, Frampton MW. "Toxicologic methods: controlled human exposures." Environmental health perspectives. 2000 Aug; 108 Suppl 4:605-13.
2000
Utell MJ, Frampton MW. "Acute health effects of ambient air pollution: the ultrafine particle hypothesis." Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine. 2000 13(4):355-59.
1999 Nov
Frampton MW, Pryor WA, Cueto R, Cox C, Morrow PE, Utell MJ. "Aldehydes (nonanal and hexanal) in rat and human bronchoalveolar lavage fluid after ozone exposure." Research report (Health Effects Institute). 1999 Nov; (90):1-15; discussion 17-8.
1999 Oct
Pietropaoli AP, Perillo IB, Torres A, Perkins PT, Frasier LM, Utell MJ, Frampton MW, Hyde RW. "Simultaneous measurement of nitric oxide production by conducting and alveolar airways of humans." Journal of applied physiology. 1999 Oct; 87(4):1532-42.
1999 Aug
Pietropaoli A, Modrak J, Utell M. "Interferon-alpha therapy associated with the development of sarcoidosis." Chest. 1999 Aug; 116(2):569-72.
1999 Apr
Frampton MW, Pryor WA, Cueto R, Cox C, Morrow PE, Utell MJ. "Ozone exposure increases aldehydes in epithelial lining fluid in human lung." American journal of respiratory and critical care medicine. 1999 Apr; 159(4 Pt 1):1134-7.
1999 Jan
Geigel EJ, Hyde RW, Perillo IB, Torres A, Perkins PT, Pietropaoli AP, Frasier LM, Frampton MW, Utell MJ. "Rate of nitric oxide production by lower alveolar airways of human lungs." Journal of applied physiology. 1999 Jan; 86(1):211-21.
1998 Aug
Utell MJ, Gelein R, Yu CP, Kenaga C, Geigel E, Torres A, Chalupa D, Gibb FR, Speers DM, Mast RW, Morrow PE. "Quantitative exposure of humans to an octamethylcyclotetrasiloxane (D4) vapor." Toxicological sciences : an official journal of the Society of Toxicology. 1998 Aug; 44(2):206-13.
1998 Aug
Looney RJ, Frampton MW, Byam J, Kenaga C, Speers DM, Cox C, Mast R, Klykken PC, Morrow PE, Utell MJ. "Acute respiratory exposure of human volunteers to octamethylcyclotetrasiloxane (D4): absence of immunological effects." Toxicological sciences : an official journal of the Society of Toxicology. 1998 Aug; 44(2):214-20.
1998 Jul
Tong Z, Utell MJ, Morrow PE, Rusch GM, Anders MW. "Metabolism of 1,1-dichloro-1-fluoroethane (HCFC-141b) in human volunteers." Drug metabolism and disposition : the biological fate of chemicals. 1998 Jul; 26(7):711-3.
1997 Sep
Torres A, Utell MJ, Morow PE, Voter KZ, Whitin JC, Cox C, Looney RJ, Speers DM, Tsai Y, Frampton MW. "Airway inflammation in smokers and nonsmokers with varying responsiveness to ozone." American journal of respiratory and critical care medicine. 1997 Sep; 156(3 Pt 1):728-36.
1997 Jun
Frampton MW, Morrow PE, Torres A, Voter KZ, Whitin JC, Cox C, Speers DM, Tsai Y, Utell MJ. "Effects of ozone on normal and potentially sensitive human subjects. Part II: Airway inflammation and responsiveness to ozone in nonsmokers and smokers." Research report (Health Effects Institute). 1997 Jun; (78):39-72; discussion 81-99.
1997 Jun
Frampton MW, Balmes JR, Cox C, Krein PM, Speers DM, Tsai Y, Utell MJ. "Effects of ozone on normal and potentially sensitive human subjects. Part III: Mediators of inflammation in bronchoalveolar lavage fluid from nonsmokers, smokers, and asthmatic subjects exposed to ozone: a collaborative study." Research report (Health Effects Institute). 1997 Jun; (78):73-9; discussion 81-99.
1997 Apr
Hyde RW, Geigel EJ, Olszowka AJ, Krasney JA, Forster RE, Utell MJ, Frampton MW. "Determination of production of nitric oxide by lower airways of humans--theory." Journal of applied physiology. 1997 Apr; 82(4):1290-6.
1997 Jan
Frampton MW, Morrow PE, Torres A, Cox C, Voter KZ, Utell MJ. "Ozone responsiveness in smokers and nonsmokers." American journal of respiratory and critical care medicine. 1997 Jan; 155(1):116-21.
1996 Jul
Rahill AA, Weiss B, Morrow PE, Frampton MW, Cox C, Gibb R, Gelein R, Speers D, Utell MJ. "Human performance during exposure to toluene." Aviation, space, and environmental medicine. 1996 Jul; 67(7):640-7.
1996 Mar
Torres A, Voter KZ, Utell MJ, Whitin JC, Morrow PE, Frampton MW. "Production of reactive oxygen intermediates following exposure to ozone. Relative contribution of alveolar macrophages." Chest. 1996 Mar; 109(3 Suppl):8S.
1995 Sep
Culp DJ, Latchney LR, Frampton MW, Jahnke MR, Morrow PE, Utell MJ. "Composition of human airway mucins and effects after inhalation of acid aerosol." The American journal of physiology. 1995 Sep; 269(3 Pt 1):L358-70.
1995 Aug
Levy PC, Utell MJ, Sickel JZ, Apostolakos MJ. "The acute respiratory distress syndrome: current trends in pathogenesis and management." Comprehensive therapy. 1995 Aug; 21(8):438-44.
1995 Apr
Frampton MW, Morrow PE, Cox C, Levy PC, Condemi JJ, Speers D, Gibb FR, Utell MJ. "Sulfuric acid aerosol followed by ozone exposure in healthy and asthmatic subjects." Environmental research. 1995 Apr; 69(1):1-14.
1995
Utell MJ, Looney RJ. "Environmentally induced asthma." Toxicology letters. 1995 82-83:47-53.
1994 Nov
Utell MJ, Frampton MW, Morrow PE, Cox C, Levy PC, Speers DM, Gibb FR. "Oxidant and acid aerosol exposure in healthy subjects and subjects with asthma. Part II: Effects of sequential sulfuric acid and ozone exposures on the pulmonary function of healthy subjects and subjects with asthma." Research report (Health Effects Institute). 1994 Nov; (70):37-93, discussion 95-112.
1994
Utell MJ, Warren J, Sawyer RF. "Public health risks from motor vehicle emissions." Annual review of public health. 1994 15:157-78.
1993 Sep
Apostolakos MJ, Schuermann WH, Frampton MW, Utell MJ, Willey JC. "Measurement of gene expression by multiplex competitive polymerase chain reaction." Analytical biochemistry. 1993 Sep; 213(2):277-84.
1992 Sep
Frampton MW, Voter KZ, Morrow PE, Roberts NJ, Culp DJ, Cox C, Utell MJ. "Sulfuric acid aerosol exposure in humans assessed by bronchoalveolar lavage." The American review of respiratory disease. 1992 Sep; 146(3):626-32.
1992 May
Smith RJ, Hyde RW, Waldman DL, Freund GG, Weber DA, Utell MJ, Morrow PE. "Effect of pattern of aerosol inhalation on clearance of technetium-99m-labeled diethylenetriamine pentaacetic acid from the lungs of normal humans." The American review of respiratory disease. 1992 May; 145(5):1109-16.
1992 Apr 30
Utell MJ, Samet JM. "Assessment of acute effects in controlled human studies. Lessons from field studies." Annals of the New York Academy of Sciences. 1992 Apr 30; 641:37-45.
1992 Feb
Morrow PE, Utell MJ, Bauer MA, Smeglin AM, Frampton MW, Cox C, Speers DM, Gibb FR. "Pulmonary performance of elderly normal subjects and subjects with chronic obstructive pulmonary disease exposed to 0.3 ppm nitrogen dioxide." The American review of respiratory disease. 1992 Feb; 145(2 Pt 1):291-300.
1992
Weiss B, Utell M, Morrow P. "Toxicological implications of extended space flights." Acta astronautica. 1992 27:239-42.
1991 Oct
Levy PC, Utell MJ, Fleit HB, Roberts NJ, Ryan DH, Looney RJ. "Characterization of human alveolar macrophage Fc gamma receptor III: a transmembrane glycoprotein that is shed under in vitro culture conditions." American journal of respiratory cell and molecular biology. 1991 Oct; 5(4):307-14.
1991 Aug
Utell MJ, Frampton MW, Roberts NJ, Finkelstein JN, Cox C, Morrow PE. "Mechanisms of nitrogen dioxide toxicity in humans." Research report (Health Effects Institute). 1991 Aug; (43):1-33.
1991 Apr
Poe RH, Utell MJ. "Theophylline in asthma and COPD: changing perspectives and controversies." Geriatrics. 1991 Apr; 46(4):55-6, 61-5.
1991 Mar
Frampton MW, Morrow PE, Cox C, Gibb FR, Speers DM, Utell MJ. "Effects of nitrogen dioxide exposure on pulmonary function and airway reactivity in normal humans." The American review of respiratory disease. 1991 Mar; 143(3):522-7.
1991
Utell MJ, Frampton MW, Morrow PE. "Air pollution and asthma: clinical studies with sulfuric acid aerosols." Allergy proceedings : the official journal of regional and state allergy societies. 1991 12(6):385-8.
1991
Frampton MW, Samet JM, Utell MJ. "Environmental factors and atmospheric pollutants." Seminars in respiratory infections. 1991 6(4):185-93.
1990 May 15
Levy PC, Looney RJ, Shen L, Graziano RF, Fanger MW, Roberts NJ, Ryan DH, Utell MJ. "Human alveolar macrophage FcR-mediated cytotoxicity. Heteroantibody- versus conventional antibody-mediated target cell lysis." The Journal of immunology : official journal of the American Association of Immunologists. 1990 May 15; 144(10):3693-700.
1990 Mar
Utell MJ, Samet JM. "Environmentally mediated disorders of the respiratory tract." The Medical clinics of North America. 1990 Mar; 74(2):291-306.
1990 Feb
Utell MJ, Schürmann WH. "[Why do we need controlled clinical studies?]." Pneumologie (Stuttgart, Germany). 1990 Feb; 44 Suppl 1:399-402.
1989 Jul
Hyde RW, Wandtke JC, Fahey PJ, Utell MJ, Plewes DB, Goske M. "Lung weight in vivo measured with computed tomography and rebreathing of soluble gases." Journal of applied physiology. 1989 Jul; 67(1):166-73.
1989 Apr
Frampton MW, Smeglin AM, Roberts NJ, Finkelstein JN, Morrow PE, Utell MJ. "Nitrogen dioxide exposure in vivo and human alveolar macrophage inactivation of influenza virus in vitro." Environmental research. 1989 Apr; 48(2):179-92.
1989 Feb
Morrow PE, Utell MJ. "Responses of susceptible subpopulations to nitrogen dioxide." Research report (Health Effects Institute). 1989 Feb; (23):1-45.
1989
Frampton MW, Finkelstein JN, Roberts NJ, Smeglin AM, Morrow PE, Utell MJ. "Effects of nitrogen dioxide exposure on bronchoalveolar lavage proteins in humans." American journal of respiratory cell and molecular biology. 1989 1(6):499-505.
1989
Poe RH, Utell MJ. "Diagnosis and management of pulmonary sarcoidosis." Comprehensive therapy. 1989 15(12):35-42.
1988 Oct
Pinkston P, Smeglin A, Roberts NJ, Gibb FR, Morrow PE, Utell MJ. "Effects of in vitro exposure to nitrogen dioxide on human alveolar macrophage release of neutrophil chemotactic factor and interleukin-1." Environmental research. 1988 Oct; 47(1):48-58.