Research Bio
Dr. Sowden received the University of Rochester Deans Institutional Award in 2002-04 to study the role of activation induced deaminase as an RNA editing enzyme in human B-cell function. Since then, he has received support from the UR Environmental Health Sciences Center and the Philip Morris External Research Program for related studies of smoking-associated carcinogenesis and teh APOBEC family of deaminases.
He is currently working with Dr. Peter Sims and Dr. Therese Wiedmer in studies of phospholipid scramblases.
2007 Mar
Lehmann DM, Galloway CA, MacElrevey C, Sowden MP, Wedekind JE, Smith HC. "Functional characterization of APOBEC-1 complementation factor phosphorylation sites." Biochimica et biophysica acta. 2007 Mar 0; 1773(3):408-18. Epub 2006 Dec 08. |
2006 Nov 10
Bennett RP, Diner E, Sowden MP, Lees JA, Wedekind JE, Smith HC. "APOBEC-1 and AID are nucleo-cytoplasmic trafficking proteins but APOBEC3G cannot traffic." Biochemical and biophysical research communications. 2006 Nov 10; 350(1):214-9. Epub 2006 Sep 18. |
2006 Jul 1
Ichikawa HT, Sowden MP, Torelli AT, Bachl J, Huang P, Dance GS, Marr SH, Robert J, Wedekind JE, Smith HC, Bottaro A. "Structural phylogenetic analysis of activation-induced deaminase function." Journal of immunology (Baltimore, Md. : 1950). 2006 Jul 1; 177(1):355-61. |
2006 Apr 15
Sparks JD, Collins HL, Chirieac DV, Cianci J, Jokinen J, Sowden MP, Galloway CA, Sparks CE. "Hepatic very-low-density lipoprotein and apolipoprotein B production are increased following in vivo induction of betaine-homocysteine S-methyltransferase." The Biochemical journal. 2006 Apr 15; 395(2):363-71. |
2006
Lehmann DM, Galloway CA, Sowden MP, Smith HC. "Metabolic regulation of apoB mRNA editing is associated with phosphorylation of APOBEC-1 complementation factor." Nucleic acids research. 2006 34(11):3299-308. Epub 2006 Jul 04. |
