Charles J. Duffy, M.D., Ph.D.

Charles J. Duffy, M.D., Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 673
Rochester, NY 14642

Office: (585) 760-6221

Research Bio

Research Focus: Functioning of cerebral neocortex, using neurophysiologic and psychophysical methods to examine mechanisms of spatial orientation

Single neuron recordings from awake monkey cerebral cortex have demonstrated the existence of neurons which are specifically activated during the viewing of optic flow fields. Our ongoing studies combine optic flow visual displays with real translational movement of the monkey using a room-sized, motorized sled. These studies are directed at characterizing the neuronal mechanisms of self-movement perception.

Our human psychophysical studies are directed at analyzing the cortical operations involved in optic flow field perception. We are focusing on studies of perceptual involvement in the syndrome of visuospatial disorientation in Alzheimer's disease and other neurodegenerative disorders.

Awards & Honors (Local)

Sloan Foundation Fellowship, Alfred P. Sloan Foundation. 1995
Roland P. MacKay Award, 22nd Essay Contest, American Academy of Neurology. 1983
William Martin Cabot Honorary Scholarship, Harvard College, Cambridge, MA. 1974

Recent Journal Articles

Showing the 5 most recent journal articles. 34 available »

2006 Nov
Mapstone M, Logan D, Duffy CJ. "Cue integration for the perception and control of self-movement in ageing and Alzheimer's disease." Brain : a journal of neurology. 2006 Nov; 129(Pt 11):2931-44.
2006 Oct
Logan DJ, Duffy CJ. "Cortical area MSTd combines visual cues to represent 3-D self-movement." Cerebral cortex. 2006 Oct; 16(10):1494-507. Epub 2005 Dec 07.
2006 Mar
Kavcic V, Fernandez R, Logan D, Duffy CJ. "Neurophysiological and perceptual correlates of navigational impairment in Alzheimer's disease." Brain : a journal of neurology. 2006 Mar; 129(Pt 3):736-46. Epub 2006 Feb 03.
Dubin, M. J.; Duffy C. J. "Behavioral Influences on Cortical Neuronal Responses to Optic Flow". Cerebral Cortex. 2006; pub online.
2005 Aug
Duffy KR, Livingstone MS. "Loss of neurofilament labeling in the primary visual cortex of monocularly deprived monkeys." Cerebral cortex. 2005 Aug; 15(8):1146-54. Epub 2004 Nov 24.

Current Appointments

Professor - Department of Neurology, Cognitive Behavioral Neurology (SMD) - Primary
Professor - Department of Neurobiology and Anatomy (SMD)
Professor - Center for Visual Science A&S (RC)


Neurology - American Board of Psychiatry and Neurology


PhD | Physiology | Johns Hopkins U Sch Medicine1984
MD | Physiology | Johns Hopkins U Sch Medicine1984
BA | Psychology | Harvard University1973

Post-Doctoral Training & Residency

Fellowship in Neurophysiology at National Institute of Health07/01/1988 - 11/30/1993
Residency in Neurology at Massachusetts General Hospital07/01/1985 - 06/30/1988
Internship in Internal Medicine at John Hopkins Univeristy School of Hygiene and Public Health07/01/1984 - 06/30/1985