Berislav V. Zlokovic, M.D., Ph.D.

Berislav V. Zlokovic, M.D., Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 670
Rochester, NY 14642

Office: (585) 273-3131
Fax: (585) 273-3133
Administrative: (585) 276-4171

Books

2004
Cheng, T.; Guo, H.; Liu, D.; Fernandez, J.A., Griffin, J.H.; Benesch, C.; Zlokovic, B.V.. "Neurovascular Protection by Activated Protein C". Pharmacology of Cerebral Ischemia 2004. Stuttgart: Medpharm, 2004.
1994
McComb, J.G.; Zlokovic, B.V.. "Cerebrospinal Fluid and the Blood-Brain Interface". Textbook of Pediatric Neurosurgery. Cheek, W.. Philadelphia: W.B. Saunders, 1994. 167-184
1993
Davson, H.; Zlokovic, B.V.; Rakic, L.M.; Segal, M.B.. An Introduction to the Blood-Brain Barrier. Davson, H.; Zlokovic, B.V.; Rakic, L.M.; Segal, M.B.. Macmillan: Houndmills, Basingstroke, Hampshire, 1993.
1992
Zlokovic, B.V.; McComb, J.G.; Segal, M.B.; Davson, H.. "Blood-Brain Barrier Permeability to Peptides and Proteins". The barriers and fluids of the eye and brain. Segal, M.B.. : MacMillan, 1992. 106-116
1992
Lipovac, M.N.; Debler, E.A.; Lajtha, A.; Zlokovic, B.V.; Jacobson, A.E.; Rice, N.C.; Popovic, A.N.; Poapadic, S.; Reith, M.E.A.. "Anticonvulsant Effects of Phencyclidine and PCP-Like Drugs on Audiogenic Seizures induced by Metaphit in Mice". The Barriers and Fluids of the Eye and Brain. Segal, M.B.. : MacMillan, 1992. 198-203
1992
Lipovac, M.N.; Susic, V.; Zlokovic, B.V.; Jacobson, A.; Rice, N.C.; Popovic, A.N.; Popadic, S.; Reith, M.E.A.. "Epileptogenic Activity of Metaphit-Induced Audiogenic Seizure in Small Rodents". The Barriers and Fluids of the Eye and Brain. Segal, M.B.. : MacMillan, 1992. 192-198
1992
Mitrovic, D.M.; Segal, M.B.; Preston, J.E.; Davson, H.; Zlokovic, B.V.. "Uptake of Thiamine by the Isolated Perfused Sheep Choroid Plexus". The Barriers and Fluids of the Eye and Brain. Segal, M.B.. : MacMillan, 1992. 188-192
1992
Rakic, L.M.; Zlokovic, B.V.; Mackic, J.B.; Lipovac, M.N.; Mitrovic, D.M.; Veskov, R.; Redzic, Z.; Segal, M.B.; Davson, H.. "Opening of the Blood-Brain Barrier to D-Mannitol Induced by Sensory-Motor Lesions in the Anaesthetized Guinea-Pig". The Barriers and Fluids of the Eye and Brain. Segal, M.B.. : Macmillan, 1992. 184-188
1992
Skundric, D.C.; Zlokovic, B.V.; Segal, M.B.; Rakic, L.; Davson, H.. "Role of Blood-Brain Barrier in Immunopathogenesis of Experimentally Induced Autoimmune Demyelination". The Barriers and Fluids of the Eye and Brain. : Macmillan, 1992. 210-214
1992
Zlokovic, B.V.; McComb, J.G.; Perlmutter, L.; Weiss, M.H.; Davson, H.. "Neuroactive Peptides and Amino Acids at the Blood-Brain Barrier: Possible Implications to Drug Abuse". Bioavailability of Drugs to the Brain and the Blood-Brain Barrier. Frankenheim, J.; Brown, R.M.. : National Institute on Drug Abuse (NIDA), 1992. 26-42
1990
Kozlowski, G.P.; Nilaver, G.; Zlokovic, B.V.. "Immunoneurology: A Serum Protein Afferent Limb to the CNS". Circulating Regulatory Factors and Neuroendocrine Function. Porter, J.C.; Jezova, D.. New York: Plenum Press, 1990. 345-370
1990
Segal, M.B.; Zlokovic, B.V.. The Blood-Brain Barrier: Amino Acids and Peptides. Segal, M.B.; Zlokovic, B.V.. Dordrecht; Boston: Kluwer Academic Publishers, 1990.
1989
Colver, J.; Skundric, D.S.; Zlokovic, B.V.. "Chain of Events Leading to Demyelination". Recent advances in multiple sclerosis therapy. Gonsette, R.E.; Delmotte, P.. New York: Elsevier Science Pub. Co., 1989. 305-308
1988
Zlokovic, B.V.; Begley, D.J.; Segal, M.B.; Davson, H.; Rakic, L.M.; Lipovac, M.N.; Mitrovic, D.M.. "Neuropeptide transport mechanism in the central nervous system". Peptide and Amino Acid Transport Mechanisms in the Central Nervous System. Rakic, L.; Begley, D.J.; Davson, H.; Zlokovic, B.V.. Stockton Press: New York, 1988. 3-19
1988
Segal, M.B.; Zlokovic, B.V.. "Factors Which Influence the Concentration of Amino Acid in Cerebrospinal Fluid". Peptide and Amino Acid Transport Mechanisms in the Central Nervous System. Rakic, L.; Begley, D.J.; Davson, H.; Zlokovic, B.V.. New York: Stockton Press, 1988. 229-239
1988
Abbott, N.J.; Zlokovic, B.V.; Taylor, M.; Hart, J.; Rogac, L.. "Amino Acid Transport by a Glial Blood-Brain Barrier: Studies in an Elasmobranch Fish". Peptide and Amino Acid Transport Mechanisms in the Central Nervous System. Rakic, L.; Begley, D.J.; Davson, H.; Zlokovic, B.V.. New York: Stockton Press, 1988. 241-244
1988
Rakic, L.M.; Begley, D.J.; Davson, H.; Zlokovic, B.V.. Peptide and Amino Acid Transport Mechanisms in the Central Nervous System. Rakic, L.M.; Begley, D.J.; Davson, H.; Zlokovic, B.V.. New York: Stockton Press, 1988.
1988
Abbott, N.J.; Butt, A.M.; Zlokovic, B.V.. "Techniques for the study of blood brain barrier in non mammalian species". Peptide and Amino Acid Transport Mechanisms in the Central Nervous System. Rakic, L.; Begley, D.J.; Davson, H.; Zlokovic, B.V.. New York: Stockton Press, 1988. 289-303
1986
Begley, D.J.; Zlokovic, B.V.. "Neuropeptides and the Blood Brain Barrier". The Blood-Brain Barrier in Health and Disease. Suckling, A.J., Rumsby, M.G.; Bradbury, M.W.B.. Deerfield Beach, FL: VCH Publishers, 1986. 98-108
1985
Zlokovic, B.V.; Segal, M.B.; Begley, D.J.. "Permeability of the isolated choroid plexus of the sheep to thyrotropin releasing hormone". Carrier Mediated Transport of Solutes from Blood to Tissue. Yudilevich, D.L.; Mann, G.E.. New York: Longman, 1985. 307-312

Journal Articles

Showing all 164 journal articles available.

2010 Sep
Vates GE, Takano T, Zlokovic B, Nedergaard M. "Pericyte constriction after stroke: the jury is still out." Nature medicine.. 2010 Sep; 16(9):959; author reply 960.
2010 Mar 4
Menon P, Deane R, Sagare A, Lane SM, Zarcone TJ, O'Dell MR, Yan C, Zlokovic BV, Berk BC. "Impaired spine formation and learning in GPCR kinase 2 interacting protein-1 (GIT1) knockout mice." Brain research. 2010 Mar 4; 1317:218-26. Epub 2010 Jan 04.
2010 Jan
Petraglia AL, Marky AH, Walker C, Thiyagarajan M, Zlokovic BV. "Activated protein C is neuroprotective and mediates new blood vessel formation and neurogenesis after controlled cortical impact." Neurosurgery.. 2010 Jan; 66(1):165-71; discussion 171-2.
2009 Nov
Zhong Z, Ilieva H, Hallagan L, Bell R, Singh I, Paquette N, Thiyagarajan M, Deane R, Fernandez JA, Lane S, Zlokovic AB, Liu T, Griffin JH, Chow N, Castellino FJ, Stojanovic K, Cleveland DW, Zlokovic BV. "Activated protein C therapy slows ALS-like disease in mice by transcriptionally inhibiting SOD1 in motor neurons and microglia cells." The Journal of clinical investigation.. 2009 Nov; 119(11):3437-49. Epub 2009 Oct 19.
2009 Jul
Bell RD, Zlokovic BV. "Neurovascular mechanisms and blood-brain barrier disorder in Alzheimer's disease." Acta neuropathologica. 2009 Jul; 118(1):103-13. Epub 2009 Mar 25.
2009 May
Wang Y, Thiyagarajan M, Chow N, Singh I, Guo H, Davis TP, Zlokovic BV. "Differential neuroprotection and risk for bleeding from activated protein C with varying degrees of anticoagulant activity." Stroke; a journal of cerebral circulation.. 2009 May; 40(5):1864-9. Epub 2008 Dec 04.
2009 Apr
Guo H, Wang Y, Singh I, Liu D, Fernández JA, Chow N, Zlokovic BV. "Species-dependent neuroprotection by activated protein C mutants with reduced anticoagulant activity." Journal of neurochemistry. 2009 Apr; 109(1):116-24. Epub 2009 Jan 23.
2009 Mar
Deane R, Bell RD, Sagare A, Zlokovic BV. "Clearance of amyloid-beta peptide across the blood-brain barrier: implication for therapies in Alzheimer's disease." CNS & neurological disorders drug targets. 2009 Mar; 8(1):16-30.
2009 Mar
Guo H, Singh I, Wang Y, Deane R, Barrett T, Fernández JA, Chow N, Griffin JH, Zlokovic BV. "Neuroprotective activities of activated protein C mutant with reduced anticoagulant activity." The European journal of neuroscience. 2009 Mar; 29(6):1119-30.
2009 Feb
Bell RD, Deane R, Chow N, Long X, Sagare A, Singh I, Streb JW, Guo H, Rubio A, Van Nostrand W, Miano JM, Zlokovic BV. "SRF and myocardin regulate LRP-mediated amyloid-beta clearance in brain vascular cells." Nature cell biology. 2009 Feb; 11(2):143-53. Epub 2008 Dec 21.
2009
Deane,R.; LaRue,B.; Sagare,A. P.; Castellino,F. J.; Zhong,Z.; Zlokovic,B. V.;. "Endothelial protein C receptor-assisted transport of activated protein C across the mouse blood-brain barrier". Journal of Cerebral Blood Flow and Metabolism. 2009; 29(1): 25-33. Link
2009
Fernández JA, Heeb MJ, Xu X, Singh I, Zlokovic BV, Griffin JH. "Species-specific anticoagulant and mitogenic activities of murine protein S." Haematologica.. 2009 94(12):1721-31. Epub 2009 Oct 08.
2008 Apr
Teng H, Zhang ZG, Wang L, Zhang RL, Zhang L, Morris D, Gregg SR, Wu Z, Jiang A, Lu M, Zlokovic BV, Chopp M. "Coupling of angiogenesis and neurogenesis in cultured endothelial cells and neural progenitor cells after stroke." Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2008 Apr; 28(4):764-71. Epub 2007 Oct 31.
2008 Apr
Zhong Z, Deane R, Ali Z, Parisi M, Shapovalov Y, O'Banion MK, Stojanovic K, Sagare A, Boillee S, Cleveland DW, Zlokovic BV. "ALS-causing SOD1 mutants generate vascular changes prior to motor neuron degeneration." Nature neuroscience.. 2008 Apr; 11(4):420-2. Epub 2008 Mar 16.
2008 Jan 24
Zlokovic BV. "The blood-brain barrier in health and chronic neurodegenerative disorders." Neuron.. 2008 Jan 24; 57(2):178-201.
2008
Long,X.; Bell,R. D.; Gerthoffer,W. T.; Zlokovic,B. V.; Miano,J. M.;. "Myocardin is sufficient for a smooth muscle-like contractile phenotype". Arteriosclerosis, Thrombosis & Vascular Biology. 2008; 28(8): 1505-1510. Link
2008
Deane,R.; Sagare,A.; Hamm,K.; Parisi,M.; Lane,S.; Finn,M. B.; Holtzman,D. M.; Zlokovic,B. V.;. "apoE isoform-specific disruption of amyloid beta peptide clearance from mouse brain". Journal of Clinical Investigation. 2008; 118(12): 4002-4013. Link
2008
Thiyagarajan,M.; Fernandez,J. A.; Lane,S. M.; Griffin,J. H.; Zlokovic,B. V.;. "Activated protein C promotes neovascularization and neurogenesis in postischemic brain via protease-activated receptor 1". Journal of Neuroscience. 2008; 28(48): 12788-12797. Link
2008
Zlokovic,B. V.;. "New therapeutic targets in the neurovascular pathway in Alzheimer's disease". Neurotherapeutics. 2008; 5(3): 409-414. Link
2008
Deane R, Sagare A, Zlokovic BV. "The role of the cell surface LRP and soluble LRP in blood-brain barrier Abeta clearance in Alzheimer's disease." Current pharmaceutical design.. 2008 14(16):1601-5.
2007 May
Bell RD, Sagare AP, Friedman AE, Bedi GS, Holtzman DM, Deane R, Zlokovic BV. "Transport pathways for clearance of human Alzheimer's amyloid beta-peptide and apolipoproteins E and J in the mouse central nervous system." Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2007 May; 27(5):909-18. Epub 2006 Nov 01.
2007 Apr 15
Mosnier LO, Zlokovic BV, Griffin JH. "The cytoprotective protein C pathway." Blood.. 2007 Apr 15; 109(8):3161-72. Epub 2006 Nov 16.
2007 Apr
Deane R, Zlokovic BV. "Role of the blood-brain barrier in the pathogenesis of Alzheimer's disease." Current Alzheimer research.. 2007 Apr; 4(2):191-7.
2007 Feb 2
Thiyagarajan M, Cheng T, Zlokovic BV. "Endothelial cell protein C receptor: role beyond endothelium?" Circulation research.. 2007 Feb 2; 100(2):155-7.
2007 Feb
Takano T, Han X, Deane R, Zlokovic B, Nedergaard M. "Two-photon imaging of astrocytic Ca2+ signaling and the microvasculature in experimental mice models of Alzheimer's disease." Annals of the New York Academy of Sciences.. 2007 Feb; 1097:40-50.
2007
Chow,N.; Bell,R. D.; Deane,R.; Streb,J. W.; Chen,J.; Brooks,A.; Van Nostrand,W.; Miano,J. M.; Zlokovic,B. V.;. "Serum response factor and myocardin mediate arterial hypercontractility and cerebral blood flow dysregulation in Alzheimer's phenotype." Proceedings of the National Academy of Sciences U.S.A.. 2007; 104(3): 823-828. Link
2007
Sagare, A.; Deane, R.; Bell, R.D.; Johnson, B.; Hamm, K.; Pendu, R.; Marky, A.; Lenting, P.J.; Wu, Z.; Zarcone, T.; Goate, A.; Mayo, K.; Perlmtter, D.; Coma, M.; Zhong, Z.; Zlokovic, B.V. ""Clearance of amayloid-beta by circulating lipoprotein receptors"". Nature Medicine. 2007; 11(9): 1029-1031. Link
2006 Nov
Cheng T, Petraglia AL, Li Z, Thiyagarajan M, Zhong Z, Wu Z, Liu D, Maggirwar SB, Deane R, Fernández JA, LaRue B, Griffin JH, Chopp M, Zlokovic BV. "Activated protein C inhibits tissue plasminogen activator-induced brain hemorrhage." Nature medicine.. 2006 Nov; 12(11):1278-85. Epub 2006 Oct 29.
2006 Apr
Zlokovic BV. "Remodeling after stroke." Nature medicine.. 2006 Apr; 12(4):390-1.
2006
Griffin JH, Fernández JA, Mosnier LO, Liu D, Cheng T, Guo H, Zlokovic BV. "The promise of protein C." Blood cells, molecules & diseases.. 2006 36(2):211-6. Epub 2006 Feb 07.
2005 Nov
Cirrito JR, Deane R, Fagan AM, Spinner ML, Parsadanian M, Finn MB, Jiang H, Prior JL, Sagare A, Bales KR, Paul SM, Zlokovic BV, Piwnica-Worms D, Holtzman DM. "P-glycoprotein deficiency at the blood-brain barrier increases amyloid-beta deposition in an Alzheimer disease mouse model." The Journal of clinical investigation.. 2005 Nov; 115(11):3285-90. Epub 2005 Oct 20.
2005 Sep
Wu Z, Guo H, Chow N, Sallstrom J, Bell RD, Deane R, Brooks AI, Kanagala S, Rubio A, Sagare A, Liu D, Li F, Armstrong D, Gasiewicz T, Zidovetzki R, Song X, Hofman F, Zlokovic BV. "Role of the MEOX2 homeobox gene in neurovascular dysfunction in Alzheimer disease." Nature medicine.. 2005 Sep; 11(9):959-65. Epub 2005 Aug 14.
2005 Sep
Zlokovic BV, Zhang C, Liu D, Fernandez J, Griffin JH, Chopp M. "Functional recovery after embolic stroke in rodents by activated protein C." Annals of neurology. 2005 Sep; 58(3):474-7.
2005 Aug
Giri RK, Rajagopal V, Shahi S, Zlokovic BV, Kalra VK. "Mechanism of amyloid peptide induced CCR5 expression in monocytes and its inhibition by siRNA for Egr-1." American journal of physiology. Cell physiology.. 2005 Aug; 289(2):C264-76. Epub 2005 Mar 02.
2005 Apr
Zlokovic BV. "Neurovascular mechanisms of Alzheimer's neurodegeneration." Trends in neurosciences. 2005 Apr; 28(4):202-8.
2005 Jan
Zlokovic BV, Deane R, Sallstrom J, Chow N, Miano JM. "Neurovascular pathways and Alzheimer amyloid beta-peptide." Brain pathology (Zurich, Switzerland). 2005 Jan; 15(1):78-83.
2005
Deane R, Sagare A, Hamm K, Parisi M, LaRue B, Guo H, Wu Z, Holtzman DM, Zlokovic BV. "IgG-assisted age-dependent clearance of Alzheimer's amyloid beta peptide by the blood-brain barrier neonatal Fc receptor." The Journal of neuroscience : the official journal of the Society for Neuroscience.. 2005 25(50):11495-503.
2004 Nov
Deane R, Wu Z, Zlokovic BV. "RAGE (yin) versus LRP (yang) balance regulates alzheimer amyloid beta-peptide clearance through transport across the blood-brain barrier." Stroke; a journal of cerebral circulation.. 2004 Nov; 35(11 Suppl 1):2628-31. Epub 2004 Sep 30.
2004 Sep 30
LaRue B, Hogg E, Sagare A, Jovanovic S, Maness L, Maurer C, Deane R, Zlokovic BV. "Method for measurement of the blood-brain barrier permeability in the perfused mouse brain: application to amyloid-beta peptide in wild type and Alzheimer's Tg2576 mice." Journal of neuroscience methods.. 2004 Sep 30; 138(1-2):233-42.
2004 Aug 5
Deane R, Wu Z, Sagare A, Davis J, Du Yan S, Hamm K, Xu F, Parisi M, LaRue B, Hu HW, Spijkers P, Guo H, Song X, Lenting PJ, Van Nostrand WE, Zlokovic BV. "LRP/amyloid beta-peptide interaction mediates differential brain efflux of Abeta isoforms." Neuron.. 2004 Aug 5; 43(3):333-44.
2004 Jun
Filbrandt CR, Wu Z, Zlokovic B, Opanashuk L, Gasiewicz TA. "Presence and functional activity of the aryl hydrocarbon receptor in isolated murine cerebral vascular endothelial cells and astrocytes." Neurotoxicology.. 2004 Jun; 25(4):605-16.
2004 May 7
Davis J, Xu F, Deane R, Romanov G, Previti ML, Zeigler K, Zlokovic BV, Van Nostrand WE. "Early-onset and robust cerebral microvascular accumulation of amyloid beta-protein in transgenic mice expressing low levels of a vasculotropic Dutch/Iowa mutant form of amyloid beta-protein precursor." The Journal of biological chemistry.. 2004 May 7; 279(19):20296-306. Epub 2004 Feb 25.
2004 May
Griffin JH, Fernández JA, Liu D, Cheng T, Guo H, Zlokovic BV. "Activated protein C and ischemic stroke." Critical care medicine.. 2004 May; 32(5 Suppl):S247-53.
2004 May
Zlokovic BV. "Clearing amyloid through the blood-brain barrier." Journal of neurochemistry. 2004 May; 89(4):807-11.
2004 Feb 19
Guo H, Liu D, Gelbard H, Cheng T, Insalaco R, Fernández JA, Griffin JH, Zlokovic BV. "Activated protein C prevents neuronal apoptosis via protease activated receptors 1 and 3." Neuron.. 2004 Feb 19; 41(4):563-72.
2004 Feb
Deane R, Zheng W, Zlokovic BV. "Brain capillary endothelium and choroid plexus epithelium regulate transport of transferrin-bound and free iron into the rat brain." Journal of neurochemistry. 2004 Feb; 88(4):813-20.
2004
Liu D, Cheng T, Guo H, Fernández JA, Griffin JH, Song X, Zlokovic BV. "Tissue plasminogen activator neurovascular toxicity is controlled by activated protein C." Nature medicine.. 2004 10(12):1379-83. Epub 2004 Oct 31.
2003 Nov 30
Wu Z, Hofman FM, Zlokovic BV. "A simple method for isolation and characterization of mouse brain microvascular endothelial cells." Journal of neuroscience methods.. 2003 Nov 30; 130(1):53-63.
2003 Jul
Deane R, Du Yan S, Submamaryan RK, LaRue B, Jovanovic S, Hogg E, Welch D, Manness L, Lin C, Yu J, Zhu H, Ghiso J, Frangione B, Stern A, Schmidt AM, Armstrong DL, Arnold B, Liliensiek B, Nawroth P, Hofman F, Kindy M, Stern D, Zlokovic B. "RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain." Nature medicine.. 2003 Jul; 9(7):907-13.
2003 Jun 15
Dömötör E, Benzakour O, Griffin JH, Yule D, Fukudome K, Zlokovic BV. "Activated protein C alters cytosolic calcium flux in human brain endothelium via binding to endothelial protein C receptor and activation of protease activated receptor-1." Blood.. 2003 Jun 15; 101(12):4797-801. Epub 2003 Feb 13.
2003 Apr 8
Liu D, Guo H, Griffin JH, Fernández JA, Zlokovic BV. "Protein S confers neuronal protection during ischemic/hypoxic injury in mice." Circulation.. 2003 Apr 8; 107(13):1791-6. Epub 2003 Mar 24.
2003 Mar
Cheng T, Liu D, Griffin JH, Fernández JA, Castellino F, Rosen ED, Fukudome K, Zlokovic BV. "Activated protein C blocks p53-mediated apoptosis in ischemic human brain endothelium and is neuroprotective." Nature medicine.. 2003 Mar; 9(3):338-42. Epub 2003 Feb 03.
2003 Feb
Amar AP, Zlokovic BV, Apuzzo ML. "Endovascular restorative neurosurgery: a novel concept for molecular and cellular therapy of the nervous system." Neurosurgery.. 2003 Feb; 52(2):402-12; discussion 412-3.
2003
Fernandez, J.A.; Xu, X.; Liu, D.; Zlokovic, B.V.; Griffin, J.H. "Recombinant murine-activated protein C is neuroprotective in a murine ischemic stroke model". Blood Cells Molecules & Diseases. 2003; 30(3): 271-276. Link
2002 Sep
Giri R, Selvaraj S, Miller CA, Hofman F, Yan SD, Stern D, Zlokovic BV, Kalra VK. "Effect of endothelial cell polarity on beta-amyloid-induced migration of monocytes across normal and AD endothelium." American journal of physiology. Cell physiology.. 2002 Sep; 283(3):C895-904.
2002 Jul
Griffin JH, Zlokovic B, Fernández JA. "Activated protein C: potential therapy for severe sepsis, thrombosis, and stroke." Seminars in hematology. 2002 Jul; 39(3):197-205.
2002 Jun
Bading JR, Yamada S, Mackic JB, Kirkman L, Miller C, Calero M, Ghiso J, Frangione B, Zlokovic BV. "Brain clearance of Alzheimer's amyloid-beta40 in the squirrel monkey: a SPECT study in a primate model of cerebral amyloid angiopathy." Journal of drug targeting. 2002 Jun; 10(4):359-68.
2002 Jun
Grammas P, Yamada M, Zlokovic B. "The cerebromicrovasculature: a key player in the pathogenesis of Alzheimer's disease." Journal of Alzheimer's disease : JAD.. 2002 Jun; 4(3):217-23.
2002 Jun
Mackic JB, Bading J, Ghiso J, Walker L, Wisniewski T, Frangione B, Zlokovic BV. "Circulating amyloid-beta peptide crosses the blood-brain barrier in aged monkeys and contributes to Alzheimer's disease lesions." Vascular pharmacology. 2002 Jun; 38(6):303-13.
2002
Zlokovic BV. "Current treatments and therapeutic targets in Alzheimer's disease." Advanced drug delivery reviews. 2002 54(12):1533-7.
2002
Zlokovic BV. "Vascular disorder in Alzheimer's disease: role in pathogenesis of dementia and therapeutic targets." Advanced drug delivery reviews. 2002 54(12):1553-9.
2002
Monro OR, Mackic JB, Yamada S, Segal MB, Ghiso J, Maurer C, Calero M, Frangione B, Zlokovic BV. "Substitution at codon 22 reduces clearance of Alzheimer's amyloid-beta peptide from the cerebrospinal fluid and prevents its transport from the central nervous system into blood." Neurobiology of aging.. 2002 23(3):405-12.
2001 May 1
Chen P, Shibata M, Zidovetzki R, Fisher M, Zlokovic BV, Hofman FM. "Endothelin-1 and monocyte chemoattractant protein-1 modulation in ischemia and human brain-derived endothelial cell cultures." Journal of neuroimmunology. 2001 May 1; 116(1):62-73.
2001 May
Zlokovic BV, Cox C. "Lower cognitive performance of older football players possessing apolipoprotein E epsilon4." Neurosurgery.. 2001 May; 48(5):1196-7.
2001 Apr 3
Shibata M, Kumar SR, Amar A, Fernandez JA, Hofman F, Griffin JH, Zlokovic BV. "Anti-inflammatory, antithrombotic, and neuroprotective effects of activated protein C in a murine model of focal ischemic stroke." Circulation.. 2001 Apr 3; 103(13):1799-805.
2001 Jan
MacDonald TJ, Taga T, Shimada H, Tabrizi P, Zlokovic BV, Cheresh DA, Laug WE. "Preferential susceptibility of brain tumors to the antiangiogenic effects of an alpha(v) integrin antagonist." Neurosurgery.. 2001 Jan; 48(1):151-7.
2000 Aug 15
Calero M, Rostagno A, Matsubara E, Zlokovic B, Frangione B, Ghiso J. "Apolipoprotein J (clusterin) and Alzheimer's disease." Microscopy research and technique. 2000 Aug 15; 50(4):305-15.
2000 Jul 26
Yan SD, Roher A, Chaney M, Zlokovic B, Schmidt AM, Stern D. "Cellular cofactors potentiating induction of stress and cytotoxicity by amyloid beta-peptide." Biochimica et biophysica acta.. 2000 Jul 26; 1502(1):145-57.
2000 Jun 1
Tokuda T, Calero M, Matsubara E, Vidal R, Kumar A, Permanne B, Zlokovic B, Smith JD, Ladu MJ, Rostagno A, Frangione B, Ghiso J. "Lipidation of apolipoprotein E influences its isoform-specific interaction with Alzheimer's amyloid beta peptides." The Biochemical journal.. 2000 Jun 1; 348 Pt 2:359-65.
2000 Jun
Ninomia T, Wang L, Kumar SR, Kim A, Zlokovic BV. "Brain injury and cerebrovascular fibrin deposition correlate with reduced antithrombotic brain capillary functions in a hypertensive stroke model." Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2000 Jun; 20(6):998-1009.
2000 Apr
Zlokovic BV, Jovanovic S, Miao W, Samara S, Verma S, Farrell CL. "Differential regulation of leptin transport by the choroid plexus and blood-brain barrier and high affinity transport systems for entry into hypothalamus and across the blood-cerebrospinal fluid barrier." Endocrinology. 2000 Apr; 141(4):1434-41.
2000
Zlokovic, B.V.; Yamada, S.; Holtzman, D.; Ghiso, J.; Frangione, B.;. "Clearance of amyloid beta-peptide from brain: transport or metabolism?[comment]". Nature Medicine. 2000; 6(7): 718-719. Link
2000
Giri R, Shen Y, Stins M, Du Yan S, Schmidt AM, Stern D, Kim KS, Zlokovic B, Kalra VK. "beta-amyloid-induced migration of monocytes across human brain endothelial cells involves RAGE and PECAM-1." American journal of physiology. Cell physiology.. 2000 279(6):C1772-81.
2000
Shibata M, Yamada S, Kumar SR, Calero M, Bading J, Frangione B, Holtzman DM, Miller CA, Strickland DK, Ghiso J, Zlokovic BV. "Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier." The Journal of clinical investigation.. 2000 106(12):1489-99.
1999 Oct
Yu H, Wang Y, Eton D, Stins M, Wang L, Apuzzo ML, Weaver FA, McComb JG, Weiss MH, Zlokovic BV. "Retroviral vector-mediated transfer and expression of human tissue plasminogen activator cDNA in bovine brain endothelial cells." Neurosurgery.. 1999 Oct; 45(4):962-8; discussion 968-70.
1999 Sep 10
Imai F, Sawada M, Suzuki H, Zlokovic BV, Kojima J, Kuno S, Nagatsu T, Nitatori T, Uchiyama Y, Kanno T. "Exogenous microglia enter the brain and migrate into ischaemic hippocampal lesions." Neuroscience letters.. 1999 Sep 10; 272(2):127-30.
1999 Sep
Mackic JB, Stins M, Jovanovic S, Kim KS, Bartus RT, Zlokovic BV. "Cereport (RMP-7) increases the permeability of human brain microvascular endothelial cell monolayers." Pharmaceutical research. 1999 Sep; 16(9):1360-5.
1999 May
Chun JT, Wang L, Pasinetti GM, Finch CE, Zlokovic BV. "Glycoprotein 330/megalin (LRP-2) has low prevalence as mRNA and protein in brain microvessels and choroid plexus." Experimental neurology.. 1999 May; 157(1):194-201.
1999 May
Kannan R, Mackic JB, Zlokovic BV. "Corneal transport of circulating glutathione in normal and galactosemic guinea pigs." Cornea.. 1999 May; 18(3):321-7.
1999
Calero M, Tokuda T, Rostagno A, Kumar A, Zlokovic B, Frangione B, Ghiso J. "Functional and structural properties of lipid-associated apolipoprotein J (clusterin)." The Biochemical journal.. 1999 344 Pt 2:375-83.
1999
Tabrizi, P.; Wang, L.; Seeds, N.; McComb, J. G.; Yamada, S.; Griffin, J. H.; Carmeliet, P.; Weiss, M. H.; Zlokovic, B. V.;. "Tissue plasminogen activator (tPA) deficiency exacerbates cerebrovascular fibrin deposition and brain injury in a murine stroke model: studies in tPA-deficient mice and wild-type mice on a matched genetic background.[see comment]". Arteriosclerosis, Thrombosis & Vascular Biology. 1999; 19(11): 2801-2806. Link
1998 Oct
Zlokovic BV, Apuzzo ML. "Strategies to circumvent vascular barriers of the central nervous system." Neurosurgery.. 1998 Oct; 43(4):877-8.
1998 Oct
Schreiber SS, Tan Z, Sun N, Wang L, Zlokovic BV. "Immunohistochemical localization of tissue plasminogen activator in vascular endothelium of stroke-prone regions of the rat brain." Neurosurgery.. 1998 Oct; 43(4):909-13.
1998 Aug 15
Mackic JB, Stins M, McComb JG, Calero M, Ghiso J, Kim KS, Yan SD, Stern D, Schmidt AM, Frangione B, Zlokovic BV. "Human blood-brain barrier receptors for Alzheimer's amyloid-beta 1- 40. Asymmetrical binding, endocytosis, and transcytosis at the apical side of brain microvascular endothelial cell monolayer." The Journal of clinical investigation.. 1998 Aug 15; 102(4):734-43.
1998 Aug 15
Tran ND, Wang L, Schreiber SS, Zlokovic B, Fisher M. "Measurement of thrombomodulin mRNA expression in brain capillaries by polymerase chain reaction." Thrombosis research.. 1998 Aug 15; 91(4):191-7.
1998 May 1
LeMay DR, Kittaka M, Gordon EM, Gray B, Stins MF, McComb JG, Jovanovic S, Tabrizi P, Weiss MH, Bartus R, Anderson WF, Zlokovic BV. "Intravenous RMP-7 increases delivery of ganciclovir into rat brain tumors and enhances the effects of herpes simplex virus thymidine kinase gene therapy." Human gene therapy. 1998 May 1; 9(7):989-95.
1998 Jan
Mackic JB, Weiss MH, Miao W, Kirkman E, Ghiso J, Calero M, Bading J, Frangione B, Zlokovic BV. "Cerebrovascular accumulation and increased blood-brain barrier permeability to circulating Alzheimer's amyloid beta peptide in aged squirrel monkey with cerebral amyloid angiopathy." Journal of neurochemistry. 1998 Jan; 70(1):210-5.
1998 Jan
Lavine SD, Hofman FM, Zlokovic BV. "Circulating antibody against tumor necrosis factor-alpha protects rat brain from reperfusion injury." Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 1998 Jan; 18(1):52-8.
1998
Wang L, Tran ND, Schreiber SS, Fisher M, Zlokovic BV. "Rat brain capillary thrombomodulin: structure and function." Thrombosis research.. 1998 92(5):213-9.
1998
MacDonald TJ, Tabrizi P, Shimada H, Zlokovic BV, Laug WE. "Detection of brain tumor invasion and micrometastasis in vivo by expression of enhanced green fluorescent protein." Neurosurgery.. 1998 43(6):1437-42; discussion 1442-3.
1997 Nov
Kittaka M, Giannotta SL, Zelman V, Correale JD, DeGiorgio CM, Weiss MH, Zlokovic BV. "Attenuation of brain injury and reduction of neuron-specific enolase by nicardipine in systemic circulation following focal ischemia and reperfusion in a rat model." Journal of neurosurgery. 1997 Nov; 87(5):731-7.
1997 Nov
Martel CL, Mackic JB, Matsubara E, Governale S, Miguel C, Miao W, McComb JG, Frangione B, Ghiso J, Zlokovic BV. "Isoform-specific effects of apolipoproteins E2, E3, and E4 on cerebral capillary sequestration and blood-brain barrier transport of circulating Alzheimer's amyloid beta." Journal of neurochemistry. 1997 Nov; 69(5):1995-2004.
1997 Apr
Zlokovic BV, Apuzzo ML. "Cellular and molecular neurosurgery: pathways from concept to reality--part I: target disorders and concept approaches to gene therapy of the central nervous system." Neurosurgery.. 1997 Apr; 40(4):789-803; discussion 803-4.
1997 Apr
Zlokovic BV, Apuzzo ML. "Cellular and molecular neurosurgery: pathways from concept to reality--part II: vector systems and delivery methodologies for gene therapy of the central nervous system." Neurosurgery.. 1997 Apr; 40(4):805-12; discussion 812-3.
1997 Apr
Kannan R, Fernández-Checa JC, García-Ruiz C, Mackic JB, Zlokovic BV. "Liver and lens glutathione and cysteine regulation in galactose-fed guinea pigs." Current eye research. 1997 Apr; 16(4):365-71.
1997 Apr
Mackic JB, Kannan R, Kaplowitz N, Zlokovic BV. "Low de novo glutathione synthesis from circulating sulfur amino acids in the lens epithelium." Experimental eye research.. 1997 Apr; 64(4):615-26.
1997 Feb
Wang L, Kittaka M, Sun N, Schreiber SS, Zlokovic BV. "Chronic nicotine treatment enhances focal ischemic brain injury and depletes free pool of brain microvascular tissue plasminogen activator in rats." Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 1997 Feb; 17(2):136-46.
1997 Jan
Elliot PJ, Bartus RT, Mackic JB, Zlokovic BV. "Intravenous infusion of RMP-7 increases ocular uptake of ganciclovir." Pharmaceutical research. 1997 Jan; 14(1):80-5.
1997
Wang, L.; Tran, N. D.; Kittaka, M.; Fisher, M. J.; Schreiber, S. S.; Zlokovic, B. V.;. "Thrombomodulin expression in bovine brain capillaries. Anticoagulant function of the blood-brain barrier, regional differences, and regulatory mechanisms". Arteriosclerosis, Thrombosis & Vascular Biology. 1997; 17(11): 3139-3146. Link
1997
Zlokovic B. "Can blood-brain barrier play a role in the development of cerebral amyloidosis and Alzheimer's disease pathology." Neurobiology of disease.. 1997 4(1):23-6.
1996 Oct
Kannan R, Yi JR, Tang D, Zlokovic BV, Kaplowitz N. "Identification of a novel, sodium-dependent, reduced glutathione transporter in the rat lens epithelium." Investigative ophthalmology & visual science.. 1996 Oct; 37(11):2269-75.
1996 Apr 30
Zlokovic BV, Martel CL, Matsubara E, McComb JG, Zheng G, McCluskey RT, Frangione B, Ghiso J. "Glycoprotein 330/megalin: probable role in receptor-mediated transport of apolipoprotein J alone and in a complex with Alzheimer disease amyloid beta at the blood-brain and blood-cerebrospinal fluid barriers." Proceedings of the National Academy of Sciences of the United States of America.. 1996 Apr 30; 93(9):4229-34.
1996 Apr 19
Kannan R, Yi JR, Tang D, Li Y, Zlokovic BV, Kaplowitz N. "Evidence for the existence of a sodium-dependent glutathione (GSH) transporter. Expression of bovine brain capillary mRNA and size fractions in Xenopus laevis oocytes and dissociation from gamma-glutamyltranspeptidase and facilitative GSH transporters." The Journal of biological chemistry.. 1996 Apr 19; 271(16):9754-8.
1996 Apr
Kittaka M, Wang L, Sun N, Schreiber SS, Seeds NW, Fisher M, Zlokovic BV. "Brain capillary tissue plasminogen activator in a diabetes stroke model." Stroke; a journal of cerebral circulation.. 1996 Apr; 27(4):712-9.
1996 Mar 15
Martel CL, Mackic JB, McComb JG, Ghiso J, Zlokovic BV. "Blood-brain barrier uptake of the 40 and 42 amino acid sequences of circulating Alzheimer's amyloid beta in guinea pigs." Neuroscience letters.. 1996 Mar 15; 206(2-3):157-60.
1996 Feb
Chen TC, Mackic JB, McComb JG, Giannotta SL, Weiss MH, Zlokovic BV. "Cellular uptake and transport of methylprednisolone at the blood-brain barrier." Neurosurgery.. 1996 Feb; 38(2):348-54.
1996 Feb
Martel CL, Mackic JB, Adams JD, McComb JG, Weiss MH, Zlokovic BV. "Transport of dopamine at the blood-brain barrier of the guinea pig: inhibition by psychotropic drugs and nicotine." Pharmaceutical research. 1996 Feb; 13(2):290-5.
1996 Jan
Mackic JB, Jinagouda S, McComb JG, Weiss MH, Kannan R, Kaplowitz N, Zlokovic BV. "Transport of circulating reduced glutathione at the basolateral side of the anterior lens epithelium: physiologic importance and manipulations." Experimental eye research.. 1996 Jan; 62(1):29-37.
1996
Redzic, Z. B.; Markovic, I. D.; Jovanovic, S. S.; Gasic, J. M.; Mitrovic, D. M.; Zlokovics, B. V.; Rakic, L. M.;. "Kinetics and sodium independence of [3H]-tiazofurin blood to brain transport in the guinea pig". Methods & Findings in Experimental & Clinical Pharmacology. 1996; 18(6): 413-418. Link
1996
Zlokovic BV. "Cerebrovascular transport of Alzheimer's amyloid beta and apolipoproteins J and E: possible anti-amyloidogenic role of the blood-brain barrier." Life sciences. 1996 59(18):1483-97.
1995 Nov
Elliott PJ, Mackic JB, Graney WF, Bartus RT, Zlokovic BV. "RMP-7, a bradykinin agonist, increases permeability of blood-ocular barriers in the guinea pig." Investigative ophthalmology & visual science.. 1995 Nov; 36(12):2542-7.
1995 Nov
Zlokovic BV, Wang L, Sun N, Haffke S, Verrall S, Seeds NW, Fisher MJ, Schreiber SS. "Expression of tissue plasminogen activator in cerebral capillaries: possible fibrinolytic function of the blood-brain barrier." Neurosurgery.. 1995 Nov; 37(5):955-61.
1995 Oct
Zlokovic BV. "Cerebrovascular permeability to peptides: manipulations of transport systems at the blood-brain barrier." Pharmaceutical research. 1995 Oct; 12(10):1395-406.
1995 Aug
Kannan R, Yi JR, Zlokovic BV, Kaplowitz N. "Molecular characterization of a reduced glutathione transporter in the lens." Investigative ophthalmology & visual science.. 1995 Aug; 36(9):1785-92.
1995
Redzic, Z. B.; Markovic, I. D.; Jovanovic, S. S.; Mitrovic, D. M.; Zlokovic, B. V.; Rakic, L. M.;. "Slow penetration of [3H] tiazofurin into guinea pig brain by a saturable mechanism". Methods & Findings in Experimental & Clinical Pharmacology. 1995; 17(6): 407-414. Link
1995
Redzi? ZB, Markovi? ID, Jovanovi? SS, Zlokovi? BV, Raki? LM. "Penetration of [3H] tiazofurin into guinea pig eye by a saturable mechanism." European journal of ophthalmology. 1995 5(2):131-5.
1994 Oct
Zlokovic BV, Mackic JB, McComb JG, Kaplowitz N, Weiss MH, Kannan R. "Blood-to-lens transport of reduced glutathione in an in situ perfused guinea-pig eye." Experimental eye research.. 1994 Oct; 59(4):487-96.
1994 Mar
Mackic JB, Ross-Cisneros FN, McComb JG, Bekhor I, Weiss MH, Kannan R, Zlokovic BV. "Galactose-induced cataract formation in guinea pigs: morphologic changes and accumulation of galactitol." Investigative ophthalmology & visual science.. 1994 Mar; 35(3):804-10.
1994
Wang, L.; McComb, J. G.; Weiss, M. H.; McDonough, A. A.; Zlokovic, B. V.;. "Nicotine downregulates alpha 2 isoform of Na,K-ATPase at the blood-brain barrier and brain in rats". Biochemical & Biophysical Research Communications. 1994; 199(3): 1422-1427. Link
1994
Zlokovic, B. V.; Mackic, J. B.; McComb, J. G.; Weiss, M. H.; Kaplowitz, N.; Kannan, R.;. "Evidence for transcapillary transport of reduced glutathione in vascular perfused guinea-pig brain". Biochemical & Biophysical Research Communications. 1994; 201(1): 402-408. Link
1994
Zlokovic, B. V.; Martel, C. L.; Mackic, J. B.; Matsubara, E.; Wisniewski, T.; McComb, J. G.; Frangione, B.; Ghiso, J.;. "Brain uptake of circulating apolipoproteins J and E complexed to Alzheimer's amyloid beta". Biochemical & Biophysical Research Communications. 1994; 205(2): 1431-1437. Link
1993 Apr 15
Zlokovic BV, Mackic JB, Wang L, McComb JG, McDonough A. "Differential expression of Na,K-ATPase alpha and beta subunit isoforms at the blood-brain barrier and the choroid plexus." The Journal of biological chemistry.. 1993 Apr 15; 268(11):8019-25.
1993 Jan
Kannan R, Tang D, Mackic JB, Zlokovic BV, Fernandez-Checa JC. "A simple technique to determine glutathione (GSH) levels and synthesis in ocular tissues as GSH-bimane adduct: application to normal and galactosemic guinea-pigs." Experimental eye research.. 1993 Jan; 56(1):45-50.
1993
Zlokovic, B. V.; Ghiso, J.; Mackic, J. B.; McComb, J. G.; Weiss, M. H.; Frangione, B.;. "Blood-brain barrier transport of circulating Alzheimer's amyloid beta". Biochemical & Biophysical Research Communications. 1993; 197(3): 1034-1040. Link
1993
Zlokovic, B. V.; Mackic, J. B.; Lipovac, M. N.; McComb, J. G.; Weiss, M. H.;. "Blood-brain transport of vasopressin". Advances in Experimental Medicine & Biology. 1993; 331: 143-147. Link
1993
Zlokovic, B. V.; McComb, J. G.; Lipovac, M. N.; Chen, T. C.; Mackic, J. B.; Schneider, J.; Gianotta, S. L.; Weiss, M. H.;. "Differential brain penetration of cerebroprotective drugs". Advances in Experimental Medicine & Biology. 1993; 331: 117-120. Link
1993
Zlokovic, B. V.; Wang, L.; Mackic, J. B.; Saraj, A. J.; McComb, J. G.; McDonough, A.;. "Expression of Na,K-ATPase at the blood-brain interface". Advances in Experimental Medicine & Biology. 1993; 331: 55-60. Link
1993
Zlokovic BV. "The blood-brain barrier in vitro: recent progress." Neurochemistry international. 1993 23(6):523.
1993
Debler EA, Lipovac MN, Lajtha A, Zlokovic BV, Dunlop DS, Jacobson AE, Rice KC, de Costa B, Reith ME. "Metaphit-induced audiogenic seizures in mice: I. Pharmacologic characterization." Epilepsia. 1993 34(2):201-10.
1993
Lipovac MN, Debler EA, Zlokovic BV, Jacobson AE, Rice KC, de Costa B, Selmeci G, Chi L, Reith ME. "Metaphit-induced audiogenic seizures in mice: II. Studies on N-methyl-D-aspartic acid, GABA, and sodium channel receptors and on the disposition of metaphit in the brain." Epilepsia. 1993 34(2):211-9.
1992 Sep 11
Zlokovic BV, Banks WA, el Kadi H, Erchegyi J, Mackic JB, McComb JG, Kastin AJ. "Transport, uptake, and metabolism of blood-borne vasopressin by the blood-brain barrier." Brain research. 1992 Sep 11; 590(1-2):213-8.
1992 Mar
Zlokovic BV, Mackic JB, McComb JG, Kannan R, Weiss MH. "An in situ perfused guinea-pig eye model for blood-ocular transport studies: application to amino acids." Experimental eye research.. 1992 Mar; 54(3):471-7.
1992
Zlokovic BV, McComb JG, Perlmutter L, Weiss MH, Davson H. "Neuroactive peptides and amino acids at the blood-brain barrier: possible implications for drug abuse." NIDA research monograph. 1992 120:26-42.
1991 Apr
Zlokovic BV, Hyman S, McComb JG, Tang G, Rezai AR, Weiss MH. "Vasopressin uptake by hypothalamopituitary axis and pineal gland in guinea pigs." The American journal of physiology.. 1991 Apr; 260(4 Pt 1):E633-40.
1991 Feb
Zlokovic BV, Segal MB, McComb JG, Hyman S, Weiss MH, Davson H. "Kinetics of circulating vasopressin uptake by choroid plexus." The American journal of physiology.. 1991 Feb; 260(2 Pt 2):F216-24.
1991
Rosic, M.; Collis, C. S.; Anjelkovic, I. Z.; Segal, M. B.; Djuric, D.; Zlokovic, B. V.;. "The effects of (R) alpha-methyl histamine on the isolated guinea pig aorta". Agents & Actions - Supplements. 1991; 33: 283-287. Link
1991
Susic V, Reith ME, Zlokovic BV, Lajtha A, Jacobson AE, Rice KC, Lipovac MN. "Electroencephalographic characteristics of audiogenic seizures induced in metaphit-treated small rodents." Epilepsia. 1991 32(6):783-90.
1990 Oct
Begley DJ, Squires LK, Zlokovi? BV, Mitrovi? DM, Hughes CC, Revest PA, Greenwood J. "Permeability of the blood-brain barrier to the immunosuppressive cyclic peptide cyclosporin A." Journal of neurochemistry. 1990 Oct; 55(4):1222-30.
1990 Jun 27
Zlokovic BV, Hyman S, McComb JG, Lipovac MN, Tang G, Davson H. "Kinetics of arginine-vasopressin uptake at the blood-brain barrier." Biochimica et biophysica acta.. 1990 Jun 27; 1025(2):191-8.
1990 May
Segal MB, Preston JE, Collis CS, Zlokovic BV. "Kinetics and Na independence of amino acid uptake by blood side of perfused sheep choroid plexus." The American journal of physiology.. 1990 May; 258(5 Pt 2):F1288-94.
1990 Mar
Zlokovic BV, Skundric DS, Segal MB, Lipovac MN, Mackic JB, Davson H. "A saturable mechanism for transport of immunoglobulin G across the blood-brain barrier of the guinea pig." Experimental neurology.. 1990 Mar; 107(3):263-70.
1990 Mar
Zlokovic BV, Segal MB, Davson H, Lipovac MN, Hyman S, McComb JG. "Circulating neuroactive peptides and the blood-brain and blood-cerebrospinal fluid barriers." Endocrinologia experimentalis. 1990 Mar; 24(1-2):9-17.
1990 Mar
Segal MB, Preston JE, Zlokovic B. "Comparison between blood and saline perfusion on the uptake of amino acids by choroid plexus of the sheep." Endocrinologia experimentalis. 1990 Mar; 24(1-2):29-36.
1990
Zlokovich, B. V.; Lipovats, M. N.; Ivanovich, T.; Aniukhovskii, E. P.; Rozenshtraukh, L. V.;. "Penetration of the anti-arrhythmia preparation ethmozin through the hemato-encephalic barrier of the guinea pig brain perfused in situ". Kardiologiia. 1990; 30(1): 69-72. Link
1990
Kozlowski GP, Nilaver G, Zlokovic BV. "Immunoneurology: a serum protein afferent limb to the CNS." Advances in experimental medicine and biology. 1990 274:345-70.
1989 Nov
Zlokovic BV, Mackic JB, Djuricic B, Davson H. "Kinetic analysis of leucine-enkephalin cellular uptake at the luminal side of the blood-brain barrier of an in situ perfused guinea-pig brain." Journal of neurochemistry. 1989 Nov; 53(5):1333-40.
1989 Jun 8
Debler EA, Lipovac MN, Lajtha A, Zlokovic BV, Jacobson AE, Rice KC, Reith ME. "Metaphit, an isothiocyanate analog of PCP, induces audiogenic seizures in mice." European journal of pharmacology. 1989 Jun 8; 165(1):155-9.
1989 Mar
Zlokovic BV, Skundric DS, Segal MB, Colover J, Jankov RM, Pejnovic N, Lackovic V, Mackic J, Lipovac MN, Davson H. "Blood-brain barrier permeability changes during acute allergic encephalomyelitis induced in the guinea pig." Metabolic brain disease. 1989 Mar; 4(1):33-40.
1989 Mar
Rakic LM, Zlokovic BV, Segal MB, Lipovac MH, Mitrovic DM, Veskov R, Mackic JB, Davson H. "Effects of sensory-motor cortical lesions on blood-brain permeability in guinea pigs." Metabolic brain disease. 1989 Mar; 4(1):9-15.
1989 Jan
Preston JE, Segal MB, Walley GJ, Zlokovic BV. "Neutral amino acid uptake by the isolated perfused sheep choroid plexus." The Journal of physiology.. 1989 Jan; 408:31-43.
1989
Rakic LM, Zlokovic BV, Davson H, Segal MB, Begley DJ, Lipovac MN, Mitrovic DM. "Chronic amphetamine intoxication and the blood-brain barrier permeability to inert polar molecules studied in the vascularly perfused guinea pig brain." Journal of the neurological sciences. 1989 94(1-3):41-50.
1989
Zlokovic BV, Susic VT, Davson H, Begley DJ, Jankov RM, Mitrovic DM, Lipovac MN. "Saturable mechanism for delta sleep-inducing peptide (DSIP) at the blood-brain barrier of the vascularly perfused guinea pig brain." Peptides. 1989 10(2):249-54.
1988 Jul
Zlokovi? BV, Lipovac MN, Begley DJ, Davson H, Raki? L. "Slow penetration of thyrotropin-releasing hormone across the blood-brain barrier of an in situ perfused guinea pig brain." Journal of neurochemistry. 1988 Jul; 51(1):252-7.
1988 Mar
Zlokovi? BV, Andjelkovi? IZ. "Glucagon effect on myocardial transport and utilization of energy-metabolites from the coronary microcirculation in the perfused rabbit heart." Archives internationales de physiologie et de biochimie. 1988 Mar; 96(1):7-16.
1988 Jan
Zlokovic BV, Segal MB, Davson H, Mitrovic DM. "Unidirectional uptake of enkephalins at the blood-tissue interface of the blood-cerebrospinal fluid barrier: a saturable mechanism." Regulatory peptides. 1988 Jan; 20(1):33-44.
1988
Zlokovic BV, Segal MB, Davson H, Jankov RM. "Passage of delta sleep-inducing peptide (DSIP) across the blood-cerebrospinal fluid barrier." Peptides. 1988 9(3):533-8.
1987 Nov
Zlokovic BV, Davson H, Preston JE, Segal MB. "The effects of aluminum chloride on the rate of secretion of the cerebrospinal fluid." Experimental neurology.. 1987 Nov; 98(2):436-52.
1987 Jul
Zlokovi? BV, Lipovac MN, Begley DJ, Davson H, Raki? L. "Transport of leucine-enkephalin across the blood-brain barrier in the perfused guinea pig brain." Journal of neurochemistry. 1987 Jul; 49(1):310-5.
1986 May
Zlokovi? BV, Begley DJ, Djurici? BM, Mitrovic DM. "Measurement of solute transport across the blood-brain barrier in the perfused guinea pig brain: method and application to N-methyl-alpha-aminoisobutyric acid." Journal of neurochemistry. 1986 May; 46(5):1444-51.
1985 Oct 10
Mann GE, Zlokovic BV, Yudilevich DL. "Evidence for a lactate transport system in the sarcolemmal membrane of the perfused rabbit heart: kinetics of unidirectional influx, carrier specificity and effects of glucagon." Biochimica et biophysica acta.. 1985 Oct 10; 819(2):241-8.
1985 Jun 10
Zlokovic BV, Begley DJ, Chain-Eliash DG. "Blood-brain barrier permeability to leucine-enkephalin, D-alanine2-D-leucine5-enkephalin and their N-terminal amino acid (tyrosine)." Brain research. 1985 Jun 10; 336(1):125-32.
1985
Zlokovi? BV, Segal MB, Begley DJ, Davson H, Raki? L. "Permeability of the blood-cerebrospinal fluid and blood-brain barriers to thyrotropin-releasing hormone." Brain research. 1985 358(1-2):191-9.
1983 Jul 18
Zlokovic BV, Begley DJ, Chain DG. "Blood-brain barrier permeability to dipeptides and their constituent amino acids." Brain research. 1983 Jul 18; 271(1):65-71.
1982 Jul
Andjelkovic I, Zlokovic B. "Protective effects of glucagon during the anaphylactic response in guinea-pig isolated heart." British journal of pharmacology.. 1982 Jul; 76(3):483-9.