Jose A. Lemos, Ph.D.

Jose A. Lemos, Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 611
Rochester, NY 14642

Office: (585) 275-1850
Lab: (585) 275-1433
Fax: (585) 276-0190

Journal Articles

Showing all 32 journal articles available.

2012 Aug
Gaca AO, Abranches J, Kajfasz JK, Lemos J. "Global transcriptional analysis of the stringent response in Enterococcus faecalis." Microbiology. 2012 Aug; 158(Pt 8):1994-2004. Epub 2012 May 31.
2012 Jul
Kajfasz JK, Mendoza JE, Gaca AO, Miller JH, Koselny KA, Giambiagi-Demarval M, Wellington M, Abranches J, Lemos JA. "The Spx regulator modulates stress responses and virulence in Enterococcus faecalis." Infection and immunity. 2012 Jul; 80(7):2265-75. Epub 2012 Apr 16.
2012 Mar
Chávez de Paz LE, Lemos JA, Wickström C, Sedgley CM. "Role of (p)ppGpp in biofilm formation by Enterococcus faecalis." Applied and environmental microbiology. 2012 Mar; 78(5):1627-30. Epub 2011 Dec 16.
2011 Oct
Kajfasz JK, Abranches J, Lemos JA. "Transcriptome analysis reveals that ClpXP proteolysis controls key virulence properties of Streptococcus mutans." Microbiology. 2011 Oct; 157(Pt 10):2880-90. Epub 2011 Aug 04.
2011 Jun
Abranches J, Miller JH, Martinez AR, Simpson-Haidaris PJ, Burne RA, Lemos JA. "The collagen-binding protein Cnm is required for Streptococcus mutans adherence to and intracellular invasion of human coronary artery endothelial cells." Infection and immunity. 2011 Jun; 79(6):2277-84. Epub 2011 Mar 21.
2011 Mar
Oliveira NE, Abranches J, Gaca AO, Laport MS, Damaso CR, Bastos MD, Lemos JA, Giambiagi-Demarval M. "clpB, a class III heat-shock gene regulated by CtsR, is involved in thermotolerance and virulence of Enterococcus faecalis." Microbiology. 2011 Mar; 157(Pt 3):656-65. Epub 2010 Dec 09.
2010 May
Kajfasz JK, Rivera-Ramos I, Abranches J, Martinez AR, Rosalen PL, Derr AM, Quivey RG, Lemos JA. "Two Spx proteins modulate stress tolerance, survival, and virulence in Streptococcus mutans." Journal of bacteriology. 2010 May; 192(10):2546-56. Epub 2010 Mar 16.
Lemos, JA, Abranches J, Koo, H, Marquis M, Burne RA. "Protocols to study the physiology of oral biofilms." Methods Mol. Biol. 2010; 666: 87-102.
Klein MI, DeBaz L, Agidi LS, Lee H, Xie G, Lin A H-M, Hamaker BR, Lemos, JA, Koo H. "2010. Dynamics of Streptococcus mutans transcriptome in response to starch and sucrose during biofilm development." PLoS One. 2010; 5: 1-13.
2009 Apr
Abranches J, Martinez AR, Kajfasz JK, Chávez V, Garsin DA, Lemos JA. "The molecular alarmone (p)ppGpp mediates stress responses, vancomycin tolerance, and virulence in Enterococcus faecalis." Journal of bacteriology. 2009 Apr; 191(7):2248-56. Epub 2009 Jan 23.
2009 Apr
Kajfasz JK, Martinez AR, Rivera-Ramos I, Abranches J, Koo H, Quivey RG, Lemos JA. "Role of Clp proteins in expression of virulence properties of Streptococcus mutans." Journal of bacteriology. 2009 Apr; 191(7):2060-8. Epub 2009 Jan 30.
Burne, RA, Ahn, SJ, Wen, ZT, Zeng, L, Lemos, JA, Abranches, J, and Nascimento, M. "Opportunities for disrupting cariogenic biofilms." Adv. Dental Res. 2009; 21: 17-20.
2008 Nov
Lemos JA, Burne RA. "A model of efficiency: stress tolerance by Streptococcus mutans." Microbiology. 2008 Nov; 154(Pt 11):3247-55.
2008 Aug
Lemos JA, Nascimento MM, Lin VK, Abranches J, Burne RA. "Global regulation by (p)ppGpp and CodY in Streptococcus mutans." Journal of bacteriology. 2008 Aug; 190(15):5291-9. Epub 2008 Jun 06.
2008 Jan
Nascimento MM, Lemos JA, Abranches J, Lin VK, Burne RA. "Role of RelA of Streptococcus mutans in global control of gene expression." Journal of bacteriology. 2008 Jan; 190(1):28-36. Epub 2007 Oct 19.
2007 Sep
Lemos JA, Lin VK, Nascimento MM, Abranches J, Burne RA. "Three gene products govern (p)ppGpp production by Streptococcus mutans." Molecular microbiology. 2007 Sep; 65(6):1568-81. Epub 2007 Aug 22.
2007 Aug
Nepomuceno RS, Tavares MB, Lemos JA, Griswold AR, Ribeiro JL, Balan A, Guimarães KS, Cai S, Burne RA, Ferreira LC, Ferreira RC. "The oligopeptide (opp) gene cluster of Streptococcus mutans: identification, prevalence, and characterization." Oral microbiology and immunology. 2007 Aug; 22(4):277-84.
2007 Mar
Lemos JA, Luzardo Y, Burne RA. "Physiologic effects of forced down-regulation of dnaK and groEL expression in Streptococcus mutans." Journal of bacteriology. 2007 Mar; 189(5):1582-8. Epub 2006 Dec 15.
2006 Mar
Laport MS, Dos Santos LL, Lemos JA, do Carmo F Bastos M, Burne RA, Giambiagi-Demarval M. "Organization of heat shock dnaK and groE operons of the nosocomial pathogen Enterococcus faecium." Research in microbiology. 2006 Mar; 157(2):162-8. Epub 2005 Aug 08.
2006 Feb
Abranches J, Lemos JA, Burne RA. "Osmotic stress responses of Streptococcus mutans UA159." FEMS microbiology letters. 2006 Feb; 255(2):240-6.
2005 May
Ahn SJ, Lemos JA, Burne RA. "Role of HtrA in growth and competence of Streptococcus mutans UA159." Journal of bacteriology. 2005 May; 187(9):3028-38.
2005 May
Brown TA, Ahn SJ, Frank RN, Chen YY, Lemos JA, Burne RA. "A hypothetical protein of Streptococcus mutans is critical for biofilm formation." Infection and immunity. 2005 May; 73(5):3147-51.
2005 Jan
Lemos JA, Abranches J, Burne RA. "Responses of cariogenic streptococci to environmental stresses." Current issues in molecular biology. 2005 Jan; 7(1):95-107.
Lemos JA, Brown TA, Abranches J, Burne RA. "Characteristics of Streptococcus mutans strains lacking the MazEF and RelBE toxin-antitoxin modules." FEMS microbiology letters. 2005 253(2):251-7. Epub 2005 Oct 13.
2004 Oct
Nascimento MM, Lemos JA, Abranches J, Gonçalves RB, Burne RA. "Adaptive acid tolerance response of Streptococcus sobrinus." Journal of bacteriology. 2004 Oct; 186(19):6383-90.
2004 May
Laport MS, Lemos JA, Bastos Md Mdo C, Burne RA, Giambiagi-De Marval M. "Transcriptional analysis of the groE and dnaK heat-shock operons of Enterococcus faecalis." Research in microbiology. 2004 May; 155(4):252-8.
2004 Mar
Lemos JA, Brown TA, Burne RA. "Effects of RelA on key virulence properties of planktonic and biofilm populations of Streptococcus mutans." Infection and immunity. 2004 Mar; 72(3):1431-40.
2002 Nov
Lemos JA, Burne RA. "Regulation and Physiological Significance of ClpC and ClpP in Streptococcus mutans." Journal of bacteriology. 2002 Nov; 184(22):6357-66.
2001 Oct
Lemos JA, Chen YY, Burne RA. "Genetic and physiologic analysis of the groE operon and role of the HrcA repressor in stress gene regulation and acid tolerance in Streptococcus mutans." Journal of bacteriology. 2001 Oct; 183(20):6074-84.
2001 Apr
Laport MS, de Castro AC, Villardo A, Lemos JA, Bastos MC, Giambiagi-deMarval M. "Expression of the major heat shock proteins DnaK and GroEL in Streptococcus pyogenes: a comparison to Enterococcus faecalis and Staphylococcus aureus." Current microbiology. 2001 Apr; 42(4):264-8.
2000 Jun
Lemos JA, Burne RA, Castro AC. "Molecular cloning, purification and immunological responses of recombinants GroEL and DnaK from Streptococcus pyogenes." FEMS immunology and medical microbiology. 2000 Jun; 28(2):121-8.
1998 Aug
Lemos JA, Giambiagi-Demarval M, Castro AC. "Expression of heat-shock proteins in Streptococcus pyogenes and their immunoreactivity with sera from patients with streptococcal diseases." Journal of medical microbiology. 1998 Aug; 47(8):711-5.


Burne RA, Abranches J, Ahn SJ, Lemos JA, Wen ZT, Zheng L.. "Functional Genomics of Streptococcus mutans". Genomic Inquiries Into Oral Bacterial Communities. Washington, DC: ASM Press, 2011.
Lemos JA, Tsakalidou E, Papadimitriou K.. "Stress responses of Streptococci". Stress Responses of Lactic Acid Bacteria. New Yoirk: Springer Science & Business Media, LLC, 2011.
Lemos, J.A.; Abranches, J.; Koo, H.; Marquis, R.E.; and Burne, R.A.. "Protocols to Study the Physiology of Oral Biofilms". Methods in Molecular Biology: Molecular Techniques and Applications in Oral Biol. New Jersey: the Humana Press, 2010. 87-102