Gloria S. Pryhuber, M.D.

Gloria S. Pryhuber, M.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 850
Rochester, NY 14642

Office: (585) 275-5948
Fax: (585) 461-3614
Lab: (585) 275-1496
Administrative: (585) 275-2972

Books

2005
Pryhuber GS, D'Angio CT, Finkelstein JN, Notter RH. "Combined-Modality Therapy for Lung Injury". Lung Injury: Mechanisms, Pathophysiology, and Therapy. Notter R, Finkelstein J, Holm BA. New York, NY: Marcel-Dekker, 2005. 779-838
2005
Whitsett JA, Rice WR, Warner BB, Wert SE, Pryhuber GS. "Acute Respiratory Disorders of the Newborn". Neonatology: Pathophysiology and Management of the Newborn. Mhairi G. MacDonald, MD Mullett and MMK Seshia. New York, NY: Lippencott, Williams and Wilkins, 2005. 563-583
1999
Whitsett JA, Pryhuber GS, Rice WR, Warner BB, Wert SE.. "Acute respiratory disorders of the newborn". Neonatology: pathophysiology and management of the newborn. Gorden B. Avery, Mary Ann Fletcher, Mhairi G. MacDonald. New York, NY: Lippencott, Williams and Wilkins, 1999. 485-508
1993
Whitsett JA, Pryhuber GS, Rice WR, Warner BB, Wert SE.. "Acute respiratory disorders of the newborn". Neonatology, Pathophysiology and Management of the Newborn. Avery GB. New York, NY: Lippencott Co., 1993. 429-452

Journal Articles

Showing all 46 journal articles available.

2013 Jun
Choo-Wing R, Syed MA, Harijith A, Bowen B, Pryhuber G, Janér C, Andersson S, Homer RJ, Bhandari V. "Hyperoxia and interferon-?-induced injury in developing lungs occur via cyclooxygenase-2 and the endoplasmic reticulum stress-dependent pathway." American journal of respiratory cell and molecular biology.. 2013 Jun; 48(6):749-57.
2012 Nov
Scheible K, Secor-Socha S, Wightman T, Wang H, Mariani TJ, Topham DJ, Pryhuber G, Quataert S. "Stability of T cell phenotype and functional assays following heparinized umbilical cord blood collection." Cytometry. Part A : the journal of the International Society for Analytical Cytology.. 2012 Nov; 81(11):937-49. Epub 2012 Oct 01.
2012 Sep
Popova AP, Bentley JK, Anyanwu AC, Richardson MN, Linn MJ, Lei J, Wong EJ, Goldsmith AM, Pryhuber GS, Hershenson MB. "Glycogen synthase kinase-3?/?-catenin signaling regulates neonatal lung mesenchymal stromal cell myofibroblastic differentiation." American journal of physiology. Lung cellular and molecular physiology.. 2012 Sep; 303(5):L439-48. Epub 2012 Jul 06.
2012 Aug 15
Bhattacharya S, Go D, Krenitsky DL, Huyck HL, Solleti SK, Lunger VA, Metlay L, Srisuma S, Wert SE, Mariani TJ, Pryhuber GS. "Genome-wide transcriptional profiling reveals connective tissue mast cell accumulation in bronchopulmonary dysplasia." American journal of respiratory and critical care medicine.. 2012 Aug 15; 186(4):349-58. Epub 2012 Jun 21.
2012
Bozyk PD, Bentley JK, Popova AP, Anyanwu AC, Linn MD, Goldsmith AM, Pryhuber GS, Moore BB, Hershenson MB. "Neonatal periostin knockout mice are protected from hyperoxia-induced alveolar simplication." PloS one. 2012 7(2):e31336. Epub 2012 Feb 17.
2011 Sep
Papuga MO, Kwok E, You Z, Rubery PT, Dougherty PE, Pryhuber G, Beck CA, Hilton MJ, Awad HA, Schwarz EM. "TNF is required for the induction but not the maintenance of compression-induced BME signals in murine tail vertebrae: limitations of anti-TNF therapy for degenerative disc disease." Journal of orthopaedic research : official publication of the Orthopaedic Research Society.. 2011 Sep; 29(9):1367-74. Epub 2011 Mar 28.
2011 Jul 15
Hwang JW, Rajendrasozhan S, Yao H, Chung S, Sundar IK, Huyck HL, Pryhuber GS, Kinnula VL, Rahman I. "FOXO3 deficiency leads to increased susceptibility to cigarette smoke-induced inflammation, airspace enlargement, and chronic obstructive pulmonary disease." The Journal of immunology : official journal of the American Association of Immunologists.. 2011 Jul 15; 187(2):987-98. Epub 2011 Jun 20.
2011 Mar 3
Scheible K, Zhang G, Baer J, Azadniv M, Lambert K, Pryhuber G, Treanor JJ, Topham DJ. "CD8+ T cell immunity to 2009 pandemic and seasonal H1N1 influenza viruses." Vaccine.. 2011 Mar 3; 29(11):2159-68. Epub 2011 Jan 04.
2011 Feb
Pressman EK, Thornburg LL, Glantz JC, Earhart A, Wall PD, Ashraf M, Pryhuber GS, Woods JR. "Inflammatory cytokines and antioxidants in midtrimester amniotic fluid: correlation with pregnancy outcome." American journal of obstetrics and gynecology.. 2011 Feb; 204(2):155.e1-7. Epub 2010 Oct 14.
2010 Apr
Stevens TP, Dylag A, Panthagani I, Pryhuber G, Halterman J. "Effect of cumulative oxygen exposure on respiratory symptoms during infancy among VLBW infants without bronchopulmonary dysplasia." Pediatric pulmonology.. 2010 Apr; 45(4):371-9.
2009 May
Saperstein S, Chen L, Oakes D, Pryhuber G, Finkelstein J. "IL-1beta augments TNF-alpha-mediated inflammatory responses from lung epithelial cells." Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research. 2009 May; 29(5):273-84.
2009 Mar 24
Pang J, Hoefen R, Pryhuber GS, Wang J, Yin G, White RJ, Xu X, O'Dell MR, Mohan A, Michaloski H, Massett MP, Yan C, Berk BC. "G-protein-coupled receptor kinase interacting protein-1 is required for pulmonary vascular development." Circulation.. 2009 Mar 24; 119(11):1524-32. Epub 2009 Mar 09.
2009
Saperstein S, Huyck H, Kimball E, Johnston C, Finkelstein J, Pryhuber G. "The effects of interleukin-1beta in tumor necrosis factor-alpha-induced acute pulmonary inflammation in mice." Mediators of inflammation. 2009 2009:958658. Epub 2009 Nov 04.
2008 Jul 15
Pryhuber GS, Huyck HL, Bhagwat S, O'Reilly MA, Finkelstein JN, Gigliotti F, Wright TW. "Parenchymal cell TNF receptors contribute to inflammatory cell recruitment and respiratory failure in Pneumocystis carinii-induced pneumonia." The Journal of immunology : official journal of the American Association of Immunologists.. 2008 Jul 15; 181(2):1409-19.
2008
Raghavendran, K, Pryhuber, GS, Chess, PR, Davidson, BA, Knight, PR and Notter, RH. "Pharmacotherapy of Acute Lung Injury and Acute Respiratory Distress Syndrome. Curr. Med. Chem." 2008; . Link
2008
Saperstein, S, Chen, L, Oakes, D, Pryhuber, G and Finkelstein, J. "IL-1beta Augments TNF-alpha-mediated Inflammatory Responses From Lung Epithelial Cells. Am J Respir Cell Mol Biol". 2008; . Link
2008
Raghavendran K, Pryhuber GS, Chess PR, Davidson BA, Knight PR, Notter RH. "Pharmacotherapy of acute lung injury and acute respiratory distress syndrome." Current medicinal chemistry. 2008 15(19):1911-24.
2006 Aug
Chess PR, D'Angio CT, Pryhuber GS, Maniscalco WM. "Pathogenesis of bronchopulmonary dysplasia." Seminars in perinatology. 2006 Aug; 30(4):171-8.
2005 Aug
Clifton DR, Rydkina E, Huyck H, Pryhuber G, Freeman RS, Silverman DJ, Sahni SK. "Expression and secretion of chemotactic cytokines IL-8 and MCP-1 by human endothelial cells after Rickettsia rickettsii infection: regulation by nuclear transcription factor NF-kappaB." International journal of medical microbiology : IJMM. 2005 Aug; 295(4):267-78.
2005 Jun 15
Lee MK, Pryhuber GS, Schwarz MA, Smith SM, Pavlova Z, Sunday ME. "Developmental regulation of p66Shc is altered by bronchopulmonary dysplasia in baboons and humans." American journal of respiratory and critical care medicine.. 2005 Jun 15; 171(12):1384-94. Epub 2005 Mar 18.
2005 Jun
Pryhuber GS, Huyck HL, Roper JM, Cornejo J, O'Reilly MA, Pierce RH, Tsitsikov EN. "Acute tumor necrosis factor-alpha-induced liver injury in the absence of tumor necrosis factor receptor-associated factor 1 gene expression." The American journal of pathology.. 2005 Jun; 166(6):1637-45.
2005
Clifton DR, Rydkina E, Huyck H, Pryhuber GS, Freeman RS, Silverman DJ, Sahni SK. "Expression and Secretion of Chemotactic Cytokines IL-8 and MCP-1 by Human Endothelial Cells after Rickettsia rickettsii Infection: Regulation by Nuclear Transcription Factor NF-kß." Int J Med Micro. 2005; 295: 267-278. Link
2004 Feb 15
Wright TW, Pryhuber GS, Chess PR, Wang Z, Notter RH, Gigliotti F. "TNF receptor signaling contributes to chemokine secretion, inflammation, and respiratory deficits during Pneumocystis pneumonia." The Journal of immunology : official journal of the American Association of Immunologists.. 2004 Feb 15; 172(4):2511-21.
2003 Mar
Pryhuber GS, Huyck HL, Baggs R, Oberdörster G, Finkelstein JN. "Induction of chemokines by low-dose intratracheal silica is reduced in TNFR I (p55) null mice." Toxicological sciences : an official journal of the Society of Toxicology.. 2003 Mar; 72(1):150-7.
2003
Mabanta CG, Pryhuber GS, Weinberg GA, Phelps DL. "Erythromycin for the prevention of chronic lung disease in intubated preterm infants at risk for, or colonized or infected with Ureaplasma urealyticum." Cochrane database of systematic reviews (Online). 2003 (4):CD003744.
2002 Apr
Maniscalco WM, Watkins RH, Pryhuber GS, Bhatt A, Shea C, Huyck H. "Angiogenic factors and alveolar vasculature: development and alterations by injury in very premature baboons." American journal of physiology. Lung cellular and molecular physiology.. 2002 Apr; 282(4):L811-23.
2002
Reynolds SD, Reynolds PR, Pryhuber GS, Finder JD, Stripp BR. "Secretoglobins SCGB3A1 and SCGB3A2 define secretory cell subsets in mouse and human airways." American journal of respiratory and critical care medicine.. 2002 166(11):1498-509. Epub 2002 Aug 01.
2001 Nov 15
Bhatt AJ, Pryhuber GS, Huyck H, Watkins RH, Metlay LA, Maniscalco WM. "Disrupted pulmonary vasculature and decreased vascular endothelial growth factor, Flt-1, and TIE-2 in human infants dying with bronchopulmonary dysplasia." American journal of respiratory and critical care medicine.. 2001 Nov 15; 164(10 Pt 1):1971-80.
2000 Oct
Uy IP, Pryhuber GS, Chess PR, Notter RH. "Combined-modality therapy with inhaled nitric oxide and exogenous surfactant in term infants with acute respiratory failure." Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 2000 Oct; 1(2):107-10.
2000 May
Pryhuber GS, O'Brien DP, Baggs R, Phipps R, Huyck H, Sanz I, Nahm MH. "Ablation of tumor necrosis factor receptor type I (p55) alters oxygen-induced lung injury." American journal of physiology. Lung cellular and molecular physiology.. 2000 May; 278(5):L1082-90.
2000 Feb
Pryhuber GS, Huyck HL, Staversky RJ, Finkelstein JN, O'Reilly MA. "Tumor necrosis factor-alpha-induced lung cell expression of antiapoptotic genes TRAF1 and cIAP2." American journal of respiratory cell and molecular biology.. 2000 Feb; 22(2):150-6.
2000
O'Reilly MA, Staversky RJ, Huyck HL, Watkins RH, LoMonaco MB, D'Angio CT, Baggs RB, Maniscalco WM, Pryhuber GS. "Bcl-2 family gene expression during severe hyperoxia induced lung injury." Laboratory investigation; a journal of technical methods and pathology.. 2000 80(12):1845-54.
1999 Sep
Khalak R, Huyck HL, Pryhuber GS. "Antagonistic effects of pyrrolidine dithiocarbamate and N-acetyl-L-cysteine on surfactant protein A and B mRNAs." Experimental lung research. 1999 Sep; 25(6):479-93.
1998 Aug
Pryhuber GS. "Regulation and function of pulmonary surfactant protein B." Molecular genetics and metabolism. 1998 Aug; 64(4):217-28.
1998 Feb
Pryhuber GS, Khalak R, Zhao Q. "Regulation of surfactant proteins A and B by TNF-alpha and phorbol ester independent of NF-kappa B." The American journal of physiology.. 1998 Feb; 274(2 Pt 1):L289-95.
1997 Sep 1
O'Reilly MA, Stripp BR, Pryhuber GS. "Epithelial-mesenchymal interactions in the alteration of gene expression and morphology following lung injury." Microscopy research and technique. 1997 Sep 1; 38(5):473-9.
1996 May
Pryhuber GS, Bachurski C, Hirsch R, Bacon A, Whitsett JA. "Tumor necrosis factor-alpha decreases surfactant protein B mRNA in murine lung." The American journal of physiology.. 1996 May; 270(5 Pt 1):L714-21.
1995 Aug 18
Bachurski CJ, Pryhuber GS, Glasser SW, Kelly SE, Whitsett JA. "Tumor necrosis factor-alpha inhibits surfactant protein C gene transcription." The Journal of biological chemistry.. 1995 Aug 18; 270(33):19402-7.
1994 Jul
Pryhuber GS, Church SL, Kroft T, Panchal A, Whitsett JA. "3'-untranslated region of SP-B mRNA mediates inhibitory effects of TPA and TNF-alpha on SP-B expression." The American journal of physiology.. 1994 Jul; 267(1 Pt 1):L16-24.
1992 Jun
Whitsett JA, Clark JC, Wispé JR, Pryhuber GS. "Effects of TNF-alpha and phorbol ester on human surfactant protein and MnSOD gene transcription in vitro." The American journal of physiology.. 1992 Jun; 262(6 Pt 1):L688-93.
1991
Pryhuber GS, Hull WM, Fink I, McMahan MJ, Whitsett JA. "Ontogeny of surfactant proteins A and B in human amniotic fluid as indices of fetal lung maturity." Pediatric research.. 1991 30(6):597-605.
1990
Pryhuber GS, O'Reilly MA, Clark JC, Hull WM, Fink I, Whitsett JA. "Phorbol ester inhibits surfactant protein SP-A and SP-B expression." The Journal of biological chemistry.. 1990 265(34):20822-8.
0
Pierce RA, Heintz C, Metlay LA, Huyck H, Pryhuber GS. "Altered Elastic Fiber Morphology, Elastin Expression, and Alveolar Myofibroblast Distribution in Human Bronchopulmonary Dysplasia." Pediatr Res. (in revision). . Link
0
Pryhuber GS, Huyck H, Kalburghi S, Macaluso K, Saperstein S, Tsitsikov E. "Enhanced TNF alpha Induced Apoptosis of Pulmonary Epithelial Cell by Inhibition of TNF Receptor Associated Protein, TRAF1". Am J Physiol (In Revision). . Link
0
Pierce, RA, Heintz, C, Metlay, LA, Huyck, H and Pryhuber, GS. "Altered Elastic Fiber Morphology, Elastin Expression, and Alveolar Myofibroblas Ddistribution in Human Bronchopulmonary Dysplasia." pediatr Res. . Link
0
Pryhuber, GS, Huyck, H, Kalburghi, S, Macaluso, K, Saperstein, S, Tsitsikov, E. "Enhanced TNF alpha Induced Apoptosis of Pulmonary Epithelial Cell by Inhibition of TNF Receptor Associated Protein, TRAF1. Am J Physiol.". Link