Zhengdong Wang, B.Med.

Zhengdong Wang, B.Med.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 655
Rochester, NY 14642

Office: (585) 275-4929

Journal Articles

Showing all 39 journal articles available.

2006 Aug
Hickman-Davis,J.; Wang,Z.; Fierro-Perez,G. A.; Chess,P. R.; Page,G. P.; Matalon,S.; Notter,R. H.;. "Surfactant Dysfunction in SP-A(-/-) and iNOS (-/-) Mice with Mycoplasma Infection". Am.J.Respir.Cell Mol.Biol.. 2006; . Link
2006 Aug
Jiang N, Wang X, Yang Y, Dai W. "Advances in mitotic inhibitors for cancer treatment." Mini reviews in medicinal chemistry. 2006 Aug; 6(8):885-95.
2006 Jun
Bruckner L, Gigliotti F, Wright T, Harmsen A, Notter RH, Chess P, Wang Z, Finkelstein J. "Pneumocystis carinii infection sensitizes lung to radiation-induced injury after syngeneic marrow transplantation: role of CD4+ T cells." American journal of physiology. Lung cellular and molecular physiology.. 2006 Jun; 290(6):L1087-96. Epub 2006 Jan 06.
2006
Robert H. Notter, Zhongyi Wang, Zhengdong Wang, Jason A. Davy, Adrian L. Schwan. "Synthesis and surface activity of diether-linked phosphoglycerols: Potential applications for exogenous lung surfactants". Bioorgan Med Chem Lett. 2006; . Link
2005 Oct
Chang Y, Wang Z, Schwan AL, Wang Z, Holm BA, Baatz JE, Notter RH. "Surface properties of sulfur- and ether-linked phosphonolipids with and without purified hydrophobic lung surfactant proteins." Chemistry and physics of lipids.. 2005 Oct; 137(1-2):77-93.
2005 Jun
Wang Z, Foye A, Chang Y, Chess PR, Wright TW, Bhagwat S, Gigliotti F, Notter RH. "Inhibition of surfactant activity by Pneumocystis carinii organisms and components in vitro." American journal of physiology. Lung cellular and molecular physiology.. 2005 Jun; 288(6):L1124-31.
2005 Apr
Davidson BA, Knight PR, Wang Z, Chess PR, Holm BA, Russo TA, Hutson A, Notter RH. "Surfactant alterations in acute inflammatory lung injury from aspiration of acid and gastric particulates." American journal of physiology. Lung cellular and molecular physiology.. 2005 Apr; 288(4):L699-708.
2005 Mar 1
Biswas N, Shanmukh S, Waring AJ, Walther F, Wang Z, Chang Y, Notter RH, Dluhy RA. "Structure and properties of phospholipid-peptide monolayers containing monomeric SP-B(1-25) I. Phases and morphology by epifluorescence microscopy." Biophysical chemistry. 2005 Mar 1; 113(3):223-32.
2005 Mar 1
Shanmukh S, Biswas N, Waring AJ, Walther FJ, Wang Z, Chang Y, Notter RH, Dluhy RA. "Structure and properties of phospholipid-peptide monolayers containing monomeric SP-B(1-25) II. Peptide conformation by infrared spectroscopy." Biophysical chemistry. 2005 Mar 1; 113(3):233-44.
2005
Elder A, Johnston C, Gelein R, Finkelstein J, Wang Z, Notter R, Oberdörster G. "Lung inflammation induced by endotoxin is enhanced in rats depleted of alveolar macrophages with aerosolized clodronate." Experimental lung research.. 2005 31(6):527-46.
2004 Mar
Elder AC, Gelein R, Oberdörster G, Finkelstein J, Notter R, Wang Z. "Efficient depletion of alveolar macrophages using intratracheally inhaled aerosols of liposome-encapsulated clodronate." Experimental lung research.. 2004 Mar; 30(2):105-20.
2004 Feb 15
Wright TW, Pryhuber GS, Chess PR, Wang Z, Notter RH, Gigliotti F. "TNF receptor signaling contributes to chemokine secretion, inflammation, and respiratory deficits during Pneumocystis pneumonia." The Journal of immunology : official journal of the American Association of Immunologists.. 2004 Feb 15; 172(4):2511-21.
2004
Chang Y, Wang Z, Notter RH, Wang Z, Qu L, Schwan AL. "Synthesis and interfacial behavior of sulfur-containing analogs of lung surfactant dipalmitoyl phosphatidylcholine." Bioorganic & medicinal chemistry letters.. 2004 14(24):5983-6.
2004
Stevens TP, Sinkin RA, Notter RH, Zhengdong Wang, Consenstein L, Maniscalco WM. "Alternative Strategies for Dispensing Exogenous Surfactant: Drug Cost Implications and In Vitro Feasibility Studies". Hospital Pharmacy. 2004; 39: 338-345. Link
2003 Sep
Zhengdong Wang, Schwan AL, Lairson LL, O'Donnell JS, Byrne GF, Foye A, Holm BA, Notter RH. "Surface activity of a synthetic lung surfactant containing a phospholipase-resistant phosphonolipid analog of dipalmitoyl phosphatidylcholine". Am J Physiol. 2003; 285: L550-L559. Link
2003 Jan
Brockman JM, Wang Z, Notter RH, Dluhy RA. "Effect of hydrophobic surfactant proteins SP-B and SP-C on binary phospholipid monolayers: II. Infrared external reflectance-absorption spectroscopy." Biophysical journal.. 2003 Jan; 84(1):326-40.
2002 Nov
Zhengdong Wang, Baatz JE, Holm BA, Notter RH. "Content-dependent activity of lung surfactant protein B (SP-B) in mixtures with lipids". Am J Physiol. 2002; 283: L897-L906. Link
2002 Feb
King DM, Wang Z, Palmer HJ, Holm BA, Notter RH. "Bulk shear viscosities of endogenous and exogenous lung surfactants." American journal of physiology. Lung cellular and molecular physiology.. 2002 Feb; 282(2):L277-84.
2002 Jan
Notter RH, Wang Z, Egan EA, Holm BA. "Component-specific surface and physiological activity in bovine-derived lung surfactants." Chemistry and physics of lipids.. 2002 Jan; 114(1):21-34.
2001 Oct
John E Baatz, Yong Zou, JT Cox JT, Zhengdong Wang, Robert H Notter. "High yield purification of lung surfactant proteins SP-B and SP-C and the effects on surface activity". Journal of Protein Expression and Purification. 2001; 23: 180-190. Link
2001 Jul
King DM, Wang Z, Kendig JW, Palmer HJ, Holm BA, Notter RH. "Concentration-dependent, temperature-dependent non-Newtonian viscosity of lung surfactant dispersions." Chemistry and physics of lipids.. 2001 Jul; 112(1):11-9.
2001 Feb
Terry W Wright, Robert H Notter, Zhengdong Wang, Allen G Harmsen, Francis Gigliotti. "Pulmonary inflammation disrupts surfactant function during pneumocystis carinii pneumonia". Infection & Immunology. 2001; 69: 758-764. Link
2000
Robert H Notter, M Apostolakos, Bruce A Holm, D Willson, Zhengdong Wang, Jacob N Finkelstein, RW Hyde. "Surfactant therapy and its potential use with other agents in term neonates, children, and adults with acute lung injury". Perspectives Neonatology. 2000; 1((4)): 4-20. Link
2000
Robert H Notter, Zhengdong Wang, Bruce A Holm. "Function and dysfunction of endogenous and exogenous lung surfactants". Research Advances in Lipids. 2000; 1: 73-105. Link
1999 Aug
Krüger P, Schalke M, Wang Z, Notter RH, Dluhy RA, Lösche M. "Effect of hydrophobic surfactant peptides SP-B and SP-C on binary phospholipid monolayers. I. Fluorescence and dark-field microscopy." Biophysical journal.. 1999 Aug; 77(2):903-14.
1999 Jul
Holm BA, Wang Z, Notter RH. "Multiple mechanisms of lung surfactant inhibition." Pediatric research.. 1999 Jul; 46(1):85-93.
1998
Zhengdong Wang, Robert H Notter. "Additivity of protein and non protein inhibitors of lung surfactant activity". American Journal of Respiratory Critical Care Medicine. 1998; Jul: 28-35. Link
1997 Oct
Zhengdong Wang, Okyanus Gurel, Susan Weinbach, Robert H Notter. "Primary importance of zwitterionic over anionic phospholipids in the surface active function of calf lung surfactant extract". American Journal of Respiratory Critical Care Medicine. 1997; 156: 1049-1057. Link
1997
Robert H Notter, Zhengdong Wang. "Pulmonary surfactant: Physical chemistry, physiology, and replacement". Reviews in Chemical Engineering. 1997; 13: 1-118. Link
1996 Aug 9
Wang Z, Gurel O, Baatz JE, Notter RH. "Acylation of pulmonary surfactant protein-C is required for its optimal surface active interactions with phospholipids." The Journal of biological chemistry.. 1996 Aug 9; 271(32):19104-9.
1996 Aug
Wang Z, Gurel O, Baatz JE, Notter RH. "Differential activity and lack of synergy of lung surfactant proteins SP-B and SP-C in interactions with phospholipids." Journal of lipid research.. 1996 Aug; 37(8):1749-60.
1996 May
Holm BA, Wang Z, Egan EA, Notter RH. "Content of dipalmitoyl phosphatidylcholine in lung surfactant: ramifications for surface activity." Pediatric research.. 1996 May; 39(5):805-11.
1996 Apr
Wang Z, Hall SB, Notter RH. "Roles of different hydrophobic constituents in the adsorption of pulmonary surfactant." Journal of lipid research.. 1996 Apr; 37(4):790-8.
1995 Jun
Wang Z, Hall SB, Notter RH. "Dynamic surface activity of films of lung surfactant phospholipids, hydrophobic proteins, and neutral lipids." Journal of lipid research.. 1995 Jun; 36(6):1283-93.
1995
Zhengfang Ge, Chris W Brown, Joseph G Turcotte, Zhengdong Wang, Robert H Notter. "FTIR studies of calcium-dependent molecular order in lung surfactant and surfactant extract dispersions". Journal of Colloid and Interface Science. 1995; 173: 471-477. Link
1994 Aug
Hall SB, Wang Z, Notter RH. "Separation of subfractions of the hydrophobic components of calf lung surfactant." Journal of lipid research.. 1994 Aug; 35(8):1386-94.
1992
Jing Yu, Jiozhi Lin, Zhihong Zhang, Shenhuan Dong, Zhengdong Wang, Hong Wang. "The pathological observation of experimental surfactant replacement therapy". The Journal of Neonatology. 1992; 7: 31-33. Link
1992
Zhonghua Wang, Shenhuan Dong, Guowei Song, Zhengdong Wang, Hong Wang, Li Zeng. "Experimental study on a lung surfactant preparation from pig lungs". Beijing Medical Journal. 1992; 14: 278-281. Link
1992
Zhengdong Wang, Shenhuan Dong. "Lung surfactant replacement therapy in lung-lavaged rabbit model". Chinese Journal of Pediatrics. 1992; 30: 299231. Link

Books

2006
Notter RH, Chess PR, Zhengdong Wang. "Lung surfactant: Overview". Encyclopedia of Respiratory Medicine. : Elsevier Ltd., 2006. 135-143
2006
Willson DF, Chess PR, Zhengdong Wang, Notter RH. "Pulmonary surfactant: Biology and therapy". Pediatric Critical Care Medicine: Basic Science and Clinical Evidence. Wheeler DA, Wong HR, Shanley TA. London, UK: Springer-Verlag, 2006.
2005
Zhengdong Wang, Holm BA, Matalon S, Notter RH. "Surfactant activity and dysfunction in lung injury". Lung Injury: Mechanisms, Pathophysiology, and Therapy. Notter RH, Finkelstein JN, Holm BA. Boca Raton, FL: Dekker/Taylor & Francis Group, 2005. 297-352
2004
Notter RH, Zhengdong Wang. "Lung surfactants". Encyclopedia of Biomaterials and Biomedical Engineering. Wnek GE, Bowlin GL. New York, NY: Marcel Dekker, Inc., 2004. 932-942
2002
Holm BA, Zhengdong Wang, Notter RH. "Lung surfactant inhibition and the importance of SP-B in inhibition-resistance". Enhorning Roundtable in Lung Research: Current Issues in Surfactant Replacement. Holm BA, Notter RH. San Antonio, TX: Dannemiller Memorial Educational Foundation and MedPro Communications, Inc., 2002. 25-32
1990
Shenhuan Dong, Zhengdong Wang, Zhonghua Wang, Guowei Song, Hong Wang, Xiaozhun Gan, Lianhua Ma, Jiozhi Lin, Di Liu, Shoshen Hu. "Surfactant replacement therapy in animal experiments". Scientific Meeting of Child Health Beyond 1990. Department of Pediatrics, Hong Kong University. Hong Kong, Singapore: Department of Pediatrics, Hong Kong University, 1990. 77-83