Professional Bio
Vyacheslav "Slava" Korshunov, Ph.D. is an Assistant Professor of Medicine in the Aab Cardiovascular Research Institute at the University of Rochester School of Medicine and Dentistry. Dr. Korshunov recieved his Ph.D. in Pharmacy (Pharmacology) from The Pyatigorsk State Academy of Pharmacy (Russia) in 2000. He completed his post-doctoral training in vascular biology in Dr. Bradford Berk's laboratory in the Center for Cardiovascular Research at the University of Rochester in 2001-2003. Dr. Korshunov established his own independent laboratory in the University of Rochester's Aab Cardiovascular Research Institute.
He serves on the Editorial Board of Atherosclerosis, Thrombosis and Vascular Biology. His current research interests include two major topics (systems genetics and candidate gene approaches) to understand mechanisms of vascular remodeling in response to hemodynamic stimuli and their impact on cardiovascular diseases.
Research Bio
Dr. Korshunov's research focuses on vascular biology. First project examines a candidate gene Axl, a receptor tyrosine kinase, in hypertension. Axl is a very promising candidate that regulates both vascular and immune cells in hypertension. Our studies will refine the current concept of the immune response in hypertension. A second project aims to discover causal genes and key pathways of the Glagov phenomenon. Originally described in atherosclerotic patients, Glagov phenomenon is a type of vascular remodeling that preserves the ability of blood to get through the artery. Therapeutic manipulation with vascular remodeling can be crucial for outcomes of cardiovascular diseases, such as heart attacks, strokes and peripheral artery diseases
| Finalist of the Junior Investigator Award | NAVBO | San Francisco, CA |
2006 - 2006 |
| Finalist of Irvine H. Page Young Investigator Research Award | AHA Council on ATVB | Washington, DC |
2005 - 2005 |
| Research Recognition Award | American Physiological Society | San Diego, CA |
2003 - 2003 |
| Diploma at the II Russian Conference of Young Scientists | Moscow, Russia |
2001 - 2001 |
| A Travel Award for Young Scientist | Goteborg, Sweden |
2000 - 2000 |
| A Diploma in The Competition Young Scientist (Pharmacist) | Moscow, Russia |
1999 - 1999 |
| 2nd place in the Competition Young Scientist (Pharmacist) | 6th National Russian Congress Man and Medicine | Moscow, Russia |
1999 |
| Honor at the Competition Young Scientists | Moscow, Russia |
1996 - 1996 |
2013 May
Pang J, Xu X, Wang X, Majumder S, Wang J, Korshunov VA, Berk BC. "G-protein-coupled receptor kinase interacting protein-1 mediates intima formation by regulating vascular smooth muscle proliferation, apoptosis, and migration." Arteriosclerosis, thrombosis, and vascular biology. 2013 May 0; 33(5):999-1005. Epub 2013 Feb 21. |
2013 May
Smolock EM, Machleder DE, Korshunov VA, Berk BC. "Identification of a genetic locus on chromosome 11 that regulates leukocyte infiltration in mouse carotid artery." Arteriosclerosis, thrombosis, and vascular biology. 2013 May 0; 33(5):1014-9. Epub 2013 Feb 28. |
2013 Apr 8
Shi G, Field DJ, Long X, Mickelsen D, Ko KA, Ture S, Korshunov VA, Miano JM, Morrell CN. "Platelet factor 4 mediates vascular smooth muscle cell injury responses." Blood. 2013 Apr 8; Epub 2013 Apr 08. |
2012
Gerloff, J.; Korshunov , V.A. "Immune modulation of vascular resident cells by axl
orchestrates carotid intima-media thickening." Am J Pathol. 2012; 180(5): 2134-2143. |
2012
Batchu, S.N.; Korshunov, V.A. "Novel tyrosine kinase signaling pathways:
implications in vascular remodeling." Curr Opin Nephrol Hypertens.. 2012; 21(2): 122-127. |