Vyacheslav A. Korshunov, Ph.D.

Vyacheslav A. Korshunov, Ph.D.

Contact Information

Aab Cardiovascular Research Institute
211 Bailey Road
West Henrietta, NY 14586

Office: (585) 276-9793
Fax: (585) 276-9830
Lab: (585) 276-9840
Administrative: (585) 276-9800

Lab Information

Dr. Korshunov's major focus is the understanding of mechanisms that regulate the structure of blood vessels (a process we call "vascular remodeling") that could prevent cardiovascular outcomes

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Professional Bio

Vyacheslav "Slava" Korshunov, Ph.D. is an Assistant Professor of Medicine in the Aab Cardiovascular Research Institute at the University of Rochester School of Medicine and Dentistry. Dr. Korshunov recieved his Ph.D. in Pharmacy (Pharmacology) from The Pyatigorsk State Academy of Pharmacy (Russia) in 2000. He completed his post-doctoral training in vascular biology in Dr. Bradford Berk's laboratory in the Center for Cardiovascular Research at the University of Rochester in 2001-2003. Dr. Korshunov established his own independent laboratory in the University of Rochester's Aab Cardiovascular Research Institute.

He serves on the Editorial Board of Atherosclerosis, Thrombosis and Vascular Biology. His current research interests include two major topics (systems genetics and candidate gene approaches) to understand mechanisms of vascular remodeling in response to hemodynamic stimuli and their impact on cardiovascular diseases.

Research Bio

Dr. Korshunov's research focuses on vascular biology. First project examines a candidate gene Axl, a receptor tyrosine kinase, in hypertension. Axl is a very promising candidate that regulates both vascular and immune cells in hypertension. Our studies will refine the current concept of the immune response in hypertension. A second project aims to discover causal genes and key pathways of the Glagov phenomenon. Originally described in atherosclerotic patients, Glagov phenomenon is a type of vascular remodeling that preserves the ability of blood to get through the artery. Therapeutic manipulation with vascular remodeling can be crucial for outcomes of cardiovascular diseases, such as heart attacks, strokes and peripheral artery diseases

Awards & Honors (National)

Finalist of the Junior Investigator Award | NAVBO | San Francisco, CA 2006 - 2006
Finalist of Irvine H. Page Young Investigator Research Award | AHA Council on ATVB | Washington, DC 2005 - 2005
Research Recognition Award | American Physiological Society | San Diego, CA 2003 - 2003
Diploma at the II Russian Conference of Young Scientists | Moscow, Russia 2001 - 2001
A Travel Award for Young Scientist | Goteborg, Sweden 2000 - 2000
A Diploma in The Competition Young Scientist (Pharmacist) | Moscow, Russia 1999 - 1999
2nd place in the Competition Young Scientist (Pharmacist) | 6th National Russian Congress Man and Medicine | Moscow, Russia 1999
Honor at the Competition Young Scientists | Moscow, Russia 1996 - 1996

Recent Journal Articles

Showing the 5 most recent journal articles. 35 available »

2013 May 23
Shi G, Field DJ, Long X, Mickelsen D, Ko KA, Ture S, Korshunov VA, Miano JM, Morrell CN. "Platelet factor 4 mediates vascular smooth muscle cell injury responses." Blood.. 2013 May 23; 121(21):4417-27. Epub 2013 Apr 08.
2013 May
Pang J, Xu X, Wang X, Majumder S, Wang J, Korshunov VA, Berk BC. "G-protein-coupled receptor kinase interacting protein-1 mediates intima formation by regulating vascular smooth muscle proliferation, apoptosis, and migration." Arteriosclerosis, thrombosis, and vascular biology.. 2013 May; 33(5):999-1005. Epub 2013 Feb 21.
2013 May
Smolock EM, Machleder DE, Korshunov VA, Berk BC. "Identification of a genetic locus on chromosome 11 that regulates leukocyte infiltration in mouse carotid artery." Arteriosclerosis, thrombosis, and vascular biology.. 2013 May; 33(5):1014-9. Epub 2013 Feb 28.
2012
Gerloff, J.; Korshunov , V.A. "Immune modulation of vascular resident cells by axl orchestrates carotid intima-media thickening." Am J Pathol. 2012; 180(5): 2134-2143. Link
2012
Batchu, S.N.; Korshunov, V.A. "Novel tyrosine kinase signaling pathways: implications in vascular remodeling." Curr Opin Nephrol Hypertens.. 2012; 21(2): 122-127. Link

Current Appointments

Associate Professor - Department of Medicine, Aab Cardiovascular Research Institute (SMD) - Primary
Associate Professor - Department of Biomedical Genetics (SMD)

Education

Ph.D. in Pharmaceutical Sciences (Pharmacology) | Pyatigorsk State Academy of Pharmacy2000
Masters in Biology | Puschino State University, Pharmacology Group1999
Diploma in Pharmacy with Honor | Pyatigorsk State Academy of Pharmacy1997
Postdoctoral Training | Cardiovascular Research | University of Rochester, Aab Cardiovascular ResearchAttended 2001 - 2003

Post-Doctoral Training & Residency

Center for Cardiovascular Research, University of Rochester, Rochester, NY, USA 2003