Paul D. Allen, Ph.D.

Paul D. Allen, Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 603
Rochester, NY 14642

Professional Bio

EDUCATION:



University of Western Australia, Perth, Australia Bachelor of Science (Physics, 1st class Honours) 1996
University of Western Australia, Perth, Australia Ph.D. (Physics) 2000

POSITIONS AND EMPLOYMENT:

The University of Western Australia, Perth, Australia:
Department of Physics Summer Vacation Scholar 1994
Honours Physics Student 1994
Part-time Teaching Assistant 1994-1998
University Postgraduate Research Scholar 1996-1999
Department of Psychology Part-time Research Assistant 1997
Department of Zoology Research Associate 1999-2000

The University of Rochester, Rochester, NY, USA:
Department of Brain & Cognitive Sciences Post-doctoral Fellow 2000-2003
Research Associate 2003- 2008
Department of Otolaryngology Research Assistant Professor 2005- 2008
Department of Neurobiology & Anatomy Research Assistant Professor 2008-present

HONOURS AND AWARDS:

Recipient of a 2004 Glenn/AFAR Research Grant for Postdoctoral Fellows.

Invited Speaker at "The Mouse as an Instrument for Central Auditory Processing Research", a workshop sponsored by the British MRC Mammalian Genetics Unit and MRC Institute of Hearing Research, held in Oxford, UK in May 2004

Australian Postgraduate Award, 1996-1999

Research Bio

RESEARCH INTERESTS:
Central Presbycusis –changes in the brain that contribute to the problems of aging-related hearing loss.
Physiological, anatomical, and molecular biological specializations of the central auditory system that facilitate the high-fidelity transmission of timing information.



PUBLICATIONS:
Leong UC, Barsz K, Allen PD, Walton JP. (2009) Neural correlates of age-related declines in frequency selectivity in the auditory midbrain., Neurobiol Aging. [Epub ahead of print]
Allen PD, Ison JR, Walton JP. (2008) Kv1.1 channel subunits are not necessary for high temporal acuity in behavioural and electrophysiological gap detection. Hear. Res. 246, 52-58
Ison, J.R, Allen, P.D., O'Neill, W.E. (2007) Age-related hearing loss in C57BL/6J mice has both frequency-specific and non-frequency-specific components that produce a hyperacusis-like exaggeration of the acoustic startle reflex. J. Assoc. Res. Otolaryngol., 8, 539-550.
Ison, J.R, Allen, P.D. (2007) Pre- but not post-menopausal female CBA/CaJ mice show less prepulse inhibition than male mice of the same age. Behav. Brain. Res., 185, 76-81
Ison, J.R., Allen, P.D., Rivoli P.J., & Moore, J.T. (2005) The behavioral response of mice to gaps in noise depends on its spectral components and its bandwidth. . J. Acoust. Soc. Am. 117, 3944-3951
Ison, J. R., & Allen, P. D. (2003) Low frequency Tone Pips Elicit Exaggerated Startle Reflexes in C57BL/6J Mice with Hearing Loss. J. Assn. Res. Otolaryngol, 4, 495-504
Allen, P.D., Burkard, R.F, Ison J.R. & Walton, J. P. (2003) Impaired gap encoding in aged mouse inferior colliculus at moderate but not high stimulus levels. Hear. Res., 186, 17-29
Ison, J. R., & Allen, P. D. (2003) A diminished rate of "physiological decay" at noise offset contributes to age-related changes in temporal acuity in the CBA mouse model of presbycusis. J. Acoust. Soc. Am, 114, 522-528
Allen P.D., Virag T.M., & Ison J.R. (2002). Humans detect gaps in broadband noise according to effective gap duration without additional cues from abrupt envelope changes. J. Acoust. Soc. Am., 112, 2967-2974
St Pierre T.G., Gorham N.T., Allen P.D., Costa-Kràmer J.L. & Rao K.V. (2002). Apparent magnetic energy barrier distribution in horse spleen ferritin: evidence for multiple interacting magnetic entities per ferrihydrite nanoparticle. Phys. Rev. B, 65, 024436
Ison J.R., Castro J., Allen P, Virag T.M., & Walton, J.P. (2002). The relative detectability for mice of gaps having different ramp durations at their onset and offset boundaries. J. Acoust. Soc. Am. 112, 740-747
Ison J.R., Virag T.M., Allen P.D., & Hammond G.R.(2002) The attention filter for tones in noise has the same shape and effective bandwidth in the elderly as it has in young listeners. J. Acoust. Soc. Am., 112, 238-246
Allen P.D., St Pierre T.G., Chua-anusorn W., Strom V. & Rao K.V. (2000) Low-frequency low-field magnetic susceptibility of ferritin and hemosiderin. Biochim. Biophys. Acta. 1500, 186-96
Allen P.D., St Pierre T.G. & Street R. (1998). Magnetic Interactions in Native Horse Spleen Ferritin below the Superparamagnetic Blocking Temperature, J Magn. Magn. Mat., 177-181, 1459-1460

Awards & Honors (Local)

Glenn/AFAR Research Grant for Postdoctoral Fellows 2004
Australian Postgraduate Award 1996 - 1999

Recent Journal Articles

Showing the 5 most recent journal articles. 22 available »

2013 Sep 18
Jalabi W, Kopp-Scheinpflug C, Allen PD, Schiavon E, Digiacomo RR, Forsythe ID, Maricich SM. "Sound localization ability and glycinergic innervation of the superior olivary complex persist after genetic deletion of the medial nucleus of the trapezoid body." The Journal of neuroscience : the official journal of the Society for Neuroscience. 2013 Sep 18; 33(38):15044-9.
2012 Jun
Ison JR, Allen PD. "Deficits in responding to brief noise offsets in Kcna1 -/- mice reveal a contribution of this gene to precise temporal processing seen previously only for stimulus onsets." Journal of the Association for Research in Otolaryngology : JARO. 2012 Jun; 13(3):351-8.
2012 Apr
Tremblay ME, Zettel ML, Ison JR, Allen PD, Majewska AK. "Effects of aging and sensory loss on glial cells in mouse visual and auditory cortices." Glia. 2012 Apr; 60(4):541-58. Epub 2012 Jan 05.
2012 Feb 15
Allen PD, Ison JR. "Kcna1 gene deletion lowers the behavioral sensitivity of mice to small changes in sound location and increases asynchronous brainstem auditory evoked potentials but does not affect hearing thresholds." The Journal of neuroscience : the official journal of the Society for Neuroscience. 2012 Feb 15; 32(7):2538-43.
2011 Jan
Leong UC, Barsz K, Allen PD, Walton JP. "Neural correlates of age-related declines in frequency selectivity in the auditory midbrain." Neurobiology of aging. 2011 Jan; 32(1):168-78. Epub 2009 Feb 25.

Current Appointments

Research Assistant Professor - Department of Neurobiology and Anatomy (SMD) - Primary

Education

PhD | Physics | Australia-U Western Australia - Perth2000
BS | Physics | Australia-U Western Australia - Perth1996