Jun-Ichi Abe, M.D., Ph.D.

Jun-Ichi Abe, M.D., Ph.D.

Contact Information

Aab Cardiovascular Research Institute
211 Bailey Road
West Henrietta, NY 14586

Office: (585) 276-9794
Fax: (585) 276-9830
Lab: (585) 276-9846
Administrative: (585) 276-9800

Journal Articles

Showing all 94 journal articles available.

2014 Jul 8
Heo KS, Cushman HJ, Akaike M, Woo CH, Wang X, Qiu X, Fujiwara K, Abe J. "ERK5 Activation in Macrophages Promotes Efferocytosis and Inhibits Atherosclerosis." Circulation.. 2014 Jul 8; 130(2):180-91. Epub 2014 Apr 28.
2014 Apr 30
Heo KS, Fujiwara K, Abe JI. "Shear Stress and Atherosclerosis." Molecules and cells.. 2014 Apr 30; Epub 2014 Apr 30.
2013 Aug 6
Abe JI, Berk BC. "Atheroprone flow activation of the sterol regulatory element binding protein 2 and nod-like receptor protein 3 inflammasome mediates focal atherosclerosis." Circulation.. 2013 Aug 6; 128(6):579-82. Epub 2013 Jul 09.
2013 Jun 7
Abe J, Berk BC. "Cezanne paints inflammation by regulating ubiquitination." Circulation research.. 2013 Jun 7; 112(12):1526-8.
2013 Mar 15
Heo KS, Chang E, Le NT, Cushman HJ, Yeh ET, Fujiwara K, Abe JI. "De-SUMOylation enzyme of sentrin/SUMO-specific protease 2 regulates disturbed flow-induced SUMOylation of ERK5 and p53 that leads to endothelial dysfunction and atherosclerosis." Circulation research.. 2013 Mar 15; 112(6):911-23. Epub 2013 Feb 04.
2013 Feb
Heo KS, Chang E, Takei Y, Le NT, Woo CH, Sullivan MA, Morrell C, Fujiwara K, Abe JI. "Phosphorylation of protein inhibitor of activated STAT1 (PIAS1) by MAPK-activated protein kinase-2 inhibits endothelial inflammation via increasing both PIAS1 transrepression and SUMO E3 ligase activity." Arteriosclerosis, thrombosis, and vascular biology.. 2013 Feb; 33(2):321-9. Epub 2012 Nov 29.
2013 Jan 29
Le NT, Heo KS, Takei Y, Lee H, Woo CH, Chang E, McClain C, Hurley C, Wang X, Li F, Xu H, Morrell C, Sullivan MA, Cohen MS, Serafimova IM, Taunton J, Fujiwara K, Abe JI. "A crucial role for p90RSK-mediated reduction of ERK5 transcriptional activity in endothelial dysfunction and atherosclerosis." Circulation.. 2013 Jan 29; 127(4):486-99. Epub 2012 Dec 14.
2012 Oct
Heo KS, Fujiwara K, Abe JI. "Glucagon-like peptide-1 and its cardiovascular effects." Current atherosclerosis reports. 2012 Oct; 14(5):422-8.
2012 Feb 17
Le NT, Takei Y, Shishido T, Woo CH, Chang E, Heo KS, Lee H, Lu Y, Morrell C, Oikawa M, McClain C, Wang X, Tournier C, Molina CA, Taunton J, Yan C, Fujiwara K, Patterson C, Yang J, Abe JI. "p90RSK targets the ERK5-CHIP ubiquitin E3 ligase activity in diabetic hearts and promotes cardiac apoptosis and dysfunction." Circulation research.. 2012 Feb 17; 110(4):536-50. Epub 2012 Jan 19.
2012
Le NT, Corsetti JP, Dehoff-Sparks JL, Sparks CE, Fujiwara K, Abe J. "Reactive Oxygen Species, SUMOylation, and Endothelial Inflammation." International journal of inflammation. 2012 2012:678190. Epub 2012 Sep 06.
2012
Kim GY, Nigro P, Fujiwara K, Abe JI, Berk BC. "p62 binding to protein kinase C ? regulates tumor necrosis factor ?-induced apoptotic pathway in endothelial cells." Arteriosclerosis, thrombosis, and vascular biology.. 2012 32(12):2974-80. Epub 2012 Sep 27.
2011 Sep 1
Nigro P, Abe JI, Berk B. "Flow shear stress and atherosclerosis: a matter of site specificity." Antioxidants & redox signaling.. 2011 Sep 1; 15(5):1405-14. Epub 2011 Apr 08.
2011 Aug
Shi X, Yan C, Nadtochiy SM, Abe JI, Brookes PS, Berk BC. "p90 ribosomal S6 kinase regulates activity of the renin-angiotensin system: a pathogenic mechanism for ischemia-reperfusion injury." Journal of molecular and cellular cardiology.. 2011 Aug; 51(2):272-5. Epub 2011 May 14.
2011 May 30
Heo KS, Lee H, Nigro P, Thomas T, Le NT, Chang E, McClain C, Reinhart-King CA, King MR, Berk BC, Fujiwara K, Woo CH, Abe J. "PKC? mediates disturbed flow-induced endothelial apoptosis via p53 SUMOylation." The Journal of cell biology. 2011 May 30; 193(5):867-84.
2011 Feb 24
Chang E, Heo KS, Woo CH, Lee H, Le NT, Thomas TN, Fujiwara K, Abe JI. "MK2 SUMOylation regulates actin filament remodeling and subsequent migration in endothelial cells by inhibiting MK2 kinase and HSP27 phosphorylation." Blood.. 2011 Feb 24; 117(8):2527-37. Epub 2010 Dec 03.
2011 Jan 17
Nigro P, Satoh K, O'Dell MR, Soe NN, Cui Z, Mohan A, Abe JI, Alexis JD, Sparks JD, Berk BC. "Cyclophilin A is an inflammatory mediator that promotes atherosclerosis in apolipoprotein E-deficient mice." The Journal of experimental medicine.. 2011 Jan 17; 208(1):53-66. Epub 2010 Dec 20.
2011
Heo KS, Fujiwara K, Abe JI. "Disturbed-flow-mediated vascular reactive oxygen species induce endothelial dysfunction." Circulation journal : official journal of the Japanese Circulation Society. 2011 75(12):2722-30. Epub 2011 Nov 10.
2010 Sep 16
Nigro P, Abe JI, Woo CH, Satoh K, McClain C, O'Dell MR, Lee H, Lim JH, Li JD, Heo KS, Fujiwara K, Berk BC. "PKCzeta decreases eNOS protein stability via inhibitory phosphorylation of ERK5." Blood.. 2010 Sep 16; 116(11):1971-9. Epub 2010 Jun 10.
2010 May 25
Jeon KI, Xu X, Aizawa T, Lim JH, Jono H, Kwon DS, Abe JI, Berk BC, Li JD, Yan C. "Vinpocetine inhibits NF-kappaB-dependent inflammation via an IKK-dependent but PDE-independent mechanism." Proceedings of the National Academy of Sciences of the United States of America.. 2010 May 25; 107(21):9795-800. Epub 2010 May 06.
2010 Apr
Woo CH, Abe JI. "SUMO--a post-translational modification with therapeutic potential?" Current opinion in pharmacology. 2010 Apr; 10(2):146-55. Epub 2010 Jan 14.
2010 Apr
Abe J, Yan C. "CCN notch signaling in vascular smooth muscle cells: good or bad?" Arteriosclerosis, thrombosis, and vascular biology.. 2010 Apr; 30(4):667-8.
2010 Mar 19
Kimura TE, Jin J, Zi M, Prehar S, Liu W, Oceandy D, Abe JI, Neyses L, Weston AH, Cartwright EJ, Wang X. "Targeted deletion of the extracellular signal-regulated protein kinase 5 attenuates hypertrophic response and promotes pressure overload-induced apoptosis in the heart." Circulation research.. 2010 Mar 19; 106(5):961-70. Epub 2010 Jan 14.
2010
Woo CH, Le NT, Shishido T, Chang E, Lee H, Heo KS, Mickelsen DM, Lu Y, McClain C, Spangenberg T, Yan C, Molina CA, Yang J, Patterson C, Abe JI. "Novel role of C terminus of Hsc70-interacting protein (CHIP) ubiquitin ligase on inhibiting cardiac apoptosis and dysfunction via regulating ERK5-mediated degradation of inducible cAMP early repressor." FASEB journal : official publication of the Federation of American Societies for Experimental Biology.. 2010 24(12):4917-28. Epub 2010 Aug 19.
2010
Jeon KI, Jono H, Miller CL, Cai Y, Lim S, Liu X, Gao P, Abe JI, Li JD, Yan C. "Ca2+/calmodulin-stimulated PDE1 regulates the beta-catenin/TCF signaling through PP2A B56 gamma subunit in proliferating vascular smooth muscle cells." The FEBS journal.. 2010 277(24):5026-39. Epub 2010 Nov 16.
2009 Nov 6
Miller CL, Oikawa M, Cai Y, Wojtovich AP, Nagel DJ, Xu X, Xu H, Florio V, Rybalkin SD, Beavo JA, Chen YF, Li JD, Blaxall BC, Abe JI, Yan C. "Role of Ca2+/calmodulin-stimulated cyclic nucleotide phosphodiesterase 1 in mediating cardiomyocyte hypertrophy." Circulation research.. 2009 Nov 6; 105(10):956-64. Epub 2009 Sep 24.
2009 Aug 11
Xie S, Lee YF, Kim E, Chen LM, Ni J, Fang LY, Liu S, Lin SJ, Abe JI, Berk B, Ho FM, Chang C. "TR4 nuclear receptor functions as a fatty acid sensor to modulate CD36 expression and foam cell formation." Proceedings of the National Academy of Sciences of the United States of America.. 2009 Aug 11; 106(32):13353-8. Epub 2009 Jul 28.
2009 Jun
Satoh K, Nigro P, Matoba T, O'Dell MR, Cui Z, Shi X, Mohan A, Yan C, Abe JI, Illig KA, Berk BC. "Cyclophilin A enhances vascular oxidative stress and the development of angiotensin II-induced aortic aneurysms." Nature medicine.. 2009 Jun; 15(6):649-56.
2009 Jan 30
Abe J, Woo CH. "NADPH oxidase in vascular injury: a new insight about its regulation and role in T cells." Circulation research.. 2009 Jan 30; 104(2):147-9.
2009 Jan 2
Alexis JD, Wang N, Che W, Lerner-Marmarosh N, Sahni A, Korshunov VA, Zou Y, Ding B, Yan C, Berk BC, Abe J. "Bcr kinase activation by angiotensin II inhibits peroxisome-proliferator-activated receptor gamma transcriptional activity in vascular smooth muscle cells." Circulation research.. 2009 Jan 2; 104(1):69-78. Epub 2008 Nov 20.
2008 Aug 1
Lu Z, Abe J, Taunton J, Lu Y, Shishido T, McClain C, Yan C, Xu SP, Spangenberg TM, Xu H. "Reactive oxygen species-induced activation of p90 ribosomal S6 kinase prolongs cardiac repolarization through inhibiting outward K+ channel activity." Circulation research.. 2008 Aug 1; 103(3):269-78. Epub 2008 Jul 03.
2008 Jun 17
Satoh K, Matoba T, Suzuki J, O'Dell MR, Nigro P, Cui Z, Mohan A, Pan S, Li L, Jin ZG, Yan C, Abe J, Berk BC. "Cyclophilin A mediates vascular remodeling by promoting inflammation and vascular smooth muscle cell proliferation." Circulation.. 2008 Jun 17; 117(24):3088-98. Epub 2008 Jun 09.
2008 Jun 6
Shishido T, Woo CH, Ding B, McClain C, Molina CA, Yan C, Yang J, Abe J. "Effects of MEK5/ERK5 association on small ubiquitin-related modification of ERK5: implications for diabetic ventricular dysfunction after myocardial infarction." Circulation research.. 2008 Jun 6; 102(11):1416-25. Epub 2008 May 08.
2008 May 23
Li L, Tatake RJ, Natarajan K, Taba Y, Garin G, Tai C, Leung E, Surapisitchat J, Yoshizumi M, Yan C, Abe J, Berk BC. "Fluid shear stress inhibits TNF-mediated JNK activation via MEK5-BMK1 in endothelial cells." Biochemical and biophysical research communications.. 2008 May 23; 370(1):159-63. Epub 2008 Mar 19.
2008 Mar 14
Woo CH, Shishido T, McClain C, Lim JH, Li JD, Yang J, Yan C, Abe J. "Extracellular signal-regulated kinase 5 SUMOylation antagonizes shear stress-induced antiinflammatory response and endothelial nitric oxide synthase expression in endothelial cells." Circulation research.. 2008 Mar 14; 102(5):538-45. Epub 2008 Jan 24.
2007 Nov 13
Pawlinski R, Tencati M, Hampton CR, Shishido T, Bullard TA, Casey LM, Andrade-Gordon P, Kotzsch M, Spring D, Luther T, Abe J, Pohlman TH, Verrier ED, Blaxall BC, Mackman N. "Protease-activated receptor-1 contributes to cardiac remodeling and hypertrophy." Circulation.. 2007 Nov 13; 116(20):2298-306. Epub 2007 Oct 29.
2007 Jul 6
Garin G, Abe J, Mohan A, Lu W, Yan C, Newby AC, Rhaman A, Berk BC. "Flow antagonizes TNF-alpha signaling in endothelial cells by inhibiting caspase-dependent PKC zeta processing." Circulation research.. 2007 Jul 6; 101(1):97-105. Epub 2007 May 24.
2007 Mar 2
Yan C, Ding B, Shishido T, Woo CH, Itoh S, Jeon KI, Liu W, Xu H, McClain C, Molina CA, Blaxall BC, Abe J. "Activation of extracellular signal-regulated kinase 5 reduces cardiac apoptosis and dysfunction via inhibition of a phosphodiesterase 3A/inducible cAMP early repressor feedback loop." Circulation research.. 2007 Mar 2; 100(4):510-9. Epub 2007 Feb 01.
2007 Mar 2
Yan C, Miller CL, Abe J. "Regulation of phosphodiesterase 3 and inducible cAMP early repressor in the heart." Circulation research.. 2007 Mar 2; 100(4):489-501.
2007 Jan 5
Goubaeva F, Mikami M, Giardina S, Ding B, Abe J, Yang J. "Cardiac mitochondrial connexin 43 regulates apoptosis." Biochemical and biophysical research communications.. 2007 Jan 5; 352(1):97-103. Epub 2006 Nov 10.
2006 Oct 27
Woo CH, Massett MP, Shishido T, Itoh S, Ding B, McClain C, Che W, Vulapalli SR, Yan C, Abe J. "ERK5 activation inhibits inflammatory responses via peroxisome proliferator-activated receptor delta (PPARdelta) stimulation." The Journal of biological chemistry.. 2006 Oct 27; 281(43):32164-74. Epub 2006 Aug 30.
2006 Oct 13
Laplante P, Raymond MA, Labelle A, Abe J, Iozzo RV, Hébert MJ. "Perlecan proteolysis induces an alpha2beta1 integrin- and Src family kinase-dependent anti-apoptotic pathway in fibroblasts in the absence of focal adhesion kinase activation." The Journal of biological chemistry.. 2006 Oct 13; 281(41):30383-92. Epub 2006 Aug 01.
2006 Jul 14
Shishido T, Nozaki N, Takahashi H, Arimoto T, Niizeki T, Koyama Y, Abe J, Takeishi Y, Kubota I. "Central role of endogenous Toll-like receptor-2 activation in regulating inflammation, reactive oxygen species production, and subsequent neointimal formation after vascular injury." Biochemical and biophysical research communications.. 2006 Jul 14; 345(4):1446-53. Epub 2006 May 16.
2006 May 30
Maekawa N, Abe J, Shishido T, Itoh S, Ding B, Sharma VK, Sheu SS, Blaxall BC, Berk BC. "Inhibiting p90 ribosomal S6 kinase prevents (Na+)-H+ exchanger-mediated cardiac ischemia-reperfusion injury." Circulation.. 2006 May 30; 113(21):2516-23. Epub 2006 May 22.
2006 Apr 11
Itoh S, Ding B, Shishido T, Lerner-Marmarosh N, Wang N, Maekawa N, Berk BC, Takeishi Y, Yan C, Blaxall BC, Abe J. "Role of p90 ribosomal S6 kinase-mediated prorenin-converting enzyme in ischemic and diabetic myocardium." Circulation.. 2006 Apr 11; 113(14):1787-98. Epub 2006 Apr 03.
2006 Jan 3
Arimoto T, Takeishi Y, Takahashi H, Shishido T, Niizeki T, Koyama Y, Shiga R, Nozaki N, Nakajima O, Nishimaru K, Abe J, Endoh M, Walsh RA, Goto K, Kubota I. "Cardiac-specific overexpression of diacylglycerol kinase zeta prevents Gq protein-coupled receptor agonist-induced cardiac hypertrophy in transgenic mice." Circulation.. 2006 Jan 3; 113(1):60-6. Epub 2005 Dec 27.
2005 Oct 11
Ding B, Abe J, Wei H, Xu H, Che W, Aizawa T, Liu W, Molina CA, Sadoshima J, Blaxall BC, Berk BC, Yan C. "A positive feedback loop of phosphodiesterase 3 (PDE3) and inducible cAMP early repressor (ICER) leads to cardiomyocyte apoptosis." Proceedings of the National Academy of Sciences of the United States of America.. 2005 Oct 11; 102(41):14771-6. Epub 2005 Sep 26.
2005 Jul 15
Itoh S, Lemay S, Osawa M, Che W, Duan Y, Tompkins A, Brookes PS, Sheu SS, Abe J. "Mitochondrial Dok-4 recruits Src kinase and regulates NF-kappaB activation in endothelial cells." The Journal of biological chemistry.. 2005 Jul 15; 280(28):26383-96. Epub 2005 Apr 26.
2005 Jun 24
Itoh S, Ding B, Bains CP, Wang N, Takeishi Y, Jalili T, King GL, Walsh RA, Yan C, Abe J. "Role of p90 ribosomal S6 kinase (p90RSK) in reactive oxygen species and protein kinase C beta (PKC-beta)-mediated cardiac troponin I phosphorylation." The Journal of biological chemistry.. 2005 Jun 24; 280(25):24135-42. Epub 2005 Apr 19.
2005 Jun 10
Pi X, Garin G, Xie L, Zheng Q, Wei H, Abe J, Yan C, Berk BC. "BMK1/ERK5 is a novel regulator of angiogenesis by destabilizing hypoxia inducible factor 1alpha." Circulation research.. 2005 Jun 10; 96(11):1145-51. Epub 2005 May 05.
2005 May 17
Ding B, Abe J, Wei H, Huang Q, Walsh RA, Molina CA, Zhao A, Sadoshima J, Blaxall BC, Berk BC, Yan C. "Functional role of phosphodiesterase 3 in cardiomyocyte apoptosis: implication in heart failure." Circulation.. 2005 May 17; 111(19):2469-76. Epub 2005 May 02.
2005 Mar 29
Takahashi H, Takeishi Y, Seidler T, Arimoto T, Akiyama H, Hozumi Y, Koyama Y, Shishido T, Tsunoda Y, Niizeki T, Nozaki N, Abe J, Hasenfuss G, Goto K, Kubota I. "Adenovirus-mediated overexpression of diacylglycerol kinase-zeta inhibits endothelin-1-induced cardiomyocyte hypertrophy." Circulation.. 2005 Mar 29; 111(12):1510-6. Epub 2005 Mar 21.
2004 Oct
Akaike M, Che W, Marmarosh NL, Ohta S, Osawa M, Ding B, Berk BC, Yan C, Abe J. "The hinge-helix 1 region of peroxisome proliferator-activated receptor gamma1 (PPARgamma1) mediates interaction with extracellular signal-regulated kinase 5 and PPARgamma1 transcriptional activation: involvement in flow-induced PPARgamma activation in endothelial cells." Molecular and cellular biology.. 2004 Oct; 24(19):8691-704.
2004 Jul 9
Osawa M, Itoh S, Ohta S, Huang Q, Berk BC, Marmarosh NL, Che W, Ding B, Yan C, Abe J. "ERK1/2 associates with the c-Met-binding domain of growth factor receptor-bound protein 2 (Grb2)-associated binder-1 (Gab1): role in ERK1/2 and early growth response factor-1 (Egr-1) nuclear accumulation." The Journal of biological chemistry.. 2004 Jul 9; 279(28):29691-9. Epub 2004 Apr 12.
2004 May 21
Cameron SJ, Itoh S, Baines CP, Zhang C, Ohta S, Che W, Glassman M, Lee JD, Yan C, Yang J, Abe J. "Activation of big MAP kinase 1 (BMK1/ERK5) inhibits cardiac injury after myocardial ischemia and reperfusion." FEBS letters.. 2004 May 21; 566(1-3):255-60.
2004 Jan 9
Cameron SJ, Abe J, Malik S, Che W, Yang J. "Differential role of MEK5alpha and MEK5beta in BMK1/ERK5 activation." The Journal of biological chemistry.. 2004 Jan 9; 279(2):1506-12. Epub 2003 Oct 28.
2003 Oct 1
Lerner-Marmarosh N, Yoshizumi M, Che W, Surapisitchat J, Kawakatsu H, Akaike M, Ding B, Huang Q, Yan C, Berk BC, Abe J. "Inhibition of tumor necrosis factor-[alpha]-induced SHP-2 phosphatase activity by shear stress: a mechanism to reduce endothelial inflammation." Arteriosclerosis, thrombosis, and vascular biology.. 2003 Oct 1; 23(10):1775-81. Epub 2003 Aug 28.
2003 Sep 5
Aizawa T, Wei H, Miano JM, Abe J, Berk BC, Yan C. "Role of phosphodiesterase 3 in NO/cGMP-mediated antiinflammatory effects in vascular smooth muscle cells." Circulation research.. 2003 Sep 5; 93(5):406-13. Epub 2003 Aug 14.
2003 May 16
Cameron SJ, Malik S, Akaike M, Lerner-Marmarosh N, Yan C, Lee JD, Abe J, Yang J. "Regulation of epidermal growth factor-induced connexin 43 gap junction communication by big mitogen-activated protein kinase1/ERK5 but not ERK1/2 kinase activation." The Journal of biological chemistry.. 2003 May 16; 278(20):18682-8. Epub 2003 Mar 12.
2003 Mar
Yoshizumi M, Abe J, Tsuchiya K, Berk BC, Tamaki T. "Stress and vascular responses: atheroprotective effect of laminar fluid shear stress in endothelial cells: possible role of mitogen-activated protein kinases." Journal of pharmacological sciences. 2003 Mar; 91(3):172-6.
2002 Nov 1
Tai LK, Okuda M, Abe J, Yan C, Berk BC. "Fluid shear stress activates proline-rich tyrosine kinase via reactive oxygen species-dependent pathway." Arteriosclerosis, thrombosis, and vascular biology.. 2002 Nov 1; 22(11):1790-6.
2002 Aug 9
Huang Q, Lerner-Marmarosh N, Che W, Ohta S, Osawa M, Yoshizumi M, Glassman M, Yan C, Berk BC, Abe J. "The novel role of the C-terminal region of SHP-2. Involvement of Gab1 and SHP-2 phosphatase activity in Elk-1 activation." The Journal of biological chemistry.. 2002 Aug 9; 277(32):29330-41. Epub 2002 May 14.
2002 Jun 28
Saito Y, Hojo Y, Tanimoto T, Abe J, Berk BC. "Protein kinase C-alpha and protein kinase C-epsilon are required for Grb2-associated binder-1 tyrosine phosphorylation in response to platelet-derived growth factor." The Journal of biological chemistry.. 2002 Jun 28; 277(26):23216-22. Epub 2002 Apr 08.
2002 Jun 14
Che W, Lerner-Marmarosh N, Huang Q, Osawa M, Ohta S, Yoshizumi M, Glassman M, Lee JD, Yan C, Berk BC, Abe J. "Insulin-like growth factor-1 enhances inflammatory responses in endothelial cells: role of Gab1 and MEKK3 in TNF-alpha-induced c-Jun and NF-kappaB activation and adhesion molecule expression." Circulation research.. 2002 Jun 14; 90(11):1222-30.
2002 Jan
Takeishi Y, Huang Q, Abe J, Che W, Lee JD, Kawakatsu H, Hoit BD, Berk BC, Walsh RA. "Activation of mitogen-activated protein kinases and p90 ribosomal S6 kinase in failing human hearts with dilated cardiomyopathy." Cardiovascular research.. 2002 Jan; 53(1):131-7.
2001 Nov
Takeishi Y, Huang Q, Wang T, Glassman M, Yoshizumi M, Baines CP, Lee JD, Kawakatsu H, Che W, Lerner-Marmarosh N, Zhang C, Yan C, Ohta S, Walsh RA, Berk BC, Abe J. "Src family kinase and adenosine differentially regulate multiple MAP kinases in ischemic myocardium: modulation of MAP kinases activation by ischemic preconditioning." Journal of molecular and cellular cardiology.. 2001 Nov; 33(11):1989-2005.
2001 Sep 18
Che W, Abe J, Yoshizumi M, Huang Q, Glassman M, Ohta S, Melaragno MG, Poppa V, Yan C, Lerner-Marmarosh N, Zhang C, Wu Y, Arlinghaus R, Berk BC. "p160 Bcr mediates platelet-derived growth factor activation of extracellular signal-regulated kinase in vascular smooth muscle cells." Circulation.. 2001 Sep 18; 104(12):1399-406.
2001 Sep
Takeishi Y, Huang Q, Abe J, Glassman M, Che W, Lee JD, Kawakatsu H, Lawrence EG, Hoit BD, Berk BC, Walsh RA. "Src and multiple MAP kinase activation in cardiac hypertrophy and congestive heart failure under chronic pressure-overload: comparison with acute mechanical stretch." Journal of molecular and cellular cardiology.. 2001 Sep; 33(9):1637-48.
2001 May 11
Lehoux S, Abe Ji , Florian JA, Berk BC. "14-3-3 Binding to Na+/H+ exchanger isoform-1 is associated with serum-dependent activation of Na+/H+ exchange." The Journal of biological chemistry.. 2001 May 11; 276(19):15794-800. Epub 2001 Feb 13.
2001 Apr 6
Yan C, Luo H, Lee JD, Abe J, Berk BC. "Molecular cloning of mouse ERK5/BMK1 splice variants and characterization of ERK5 functional domains." The Journal of biological chemistry.. 2001 Apr 6; 276(14):10870-8. Epub 2001 Jan 03.
2001
Abe JI, Che W, Yoshizumi M, Huang Q, Glassman M, Ohta S, Wu Y, Arlinghaus R, Berk BC. "Bcr in vascular smooth muscle cells involvement of Ras and Raf-1 activation by Bcr." Annals of the New York Academy of Sciences.. 2001 947:341-3.
2001
Berk BC, Abe JI, Min W, Surapisitchat J, Yan C. "Endothelial atheroprotective and anti-inflammatory mechanisms." Annals of the New York Academy of Sciences.. 2001 947:93-109; discussion 109-11.
2000 Apr 21
Yoshizumi M, Abe J, Haendeler J, Huang Q, Berk BC. "Src and Cas mediate JNK activation but not ERK1/2 and p38 kinases by reactive oxygen species." The Journal of biological chemistry.. 2000 Apr 21; 275(16):11706-12.
2000 Jan 21
Abe J, Okuda M, Huang Q, Yoshizumi M, Berk BC. "Reactive oxygen species activate p90 ribosomal S6 kinase via Fyn and Ras." The Journal of biological chemistry.. 2000 Jan 21; 275(3):1739-48.
1999 Jul 23
Abe J, Berk BC. "Fyn and JAK2 mediate Ras activation by reactive oxygen species." The Journal of biological chemistry.. 1999 Jul 23; 274(30):21003-10.
1999 Jul 16
Takahashi E, Abe J, Gallis B, Aebersold R, Spring DJ, Krebs EG, Berk BC. "p90(RSK) is a serum-stimulated Na+/H+ exchanger isoform-1 kinase. Regulatory phosphorylation of serine 703 of Na+/H+ exchanger isoform-1." The Journal of biological chemistry.. 1999 Jul 16; 274(29):20206-14.
1999 Jun
Deguchi J, Namba T, Hamada H, Nakaoka T, Abe J, Sato O, Miyata T, Makuuchi M, Kurokawa K, Takuwa Y. "Targeting endogenous platelet-derived growth factor B-chain by adenovirus-mediated gene transfer potently inhibits in vivo smooth muscle proliferation after arterial injury." Gene therapy.. 1999 Jun; 6(6):956-65.
1999
Takeishi Y, Abe J, Lee JD, Kawakatsu H, Walsh RA, Berk BC. "Differential regulation of p90 ribosomal S6 kinase and big mitogen-activated protein kinase 1 by ischemia/reperfusion and oxidative stress in perfused guinea pig hearts." Circulation research.. 1999 85(12):1164-72.
1999
Deguchi J, Abe J, Makuuchi M, Takuwa Y. "Inhibitory effects of trapidil on PDGF signaling in balloon-injured rat carotid artery." Life sciences.. 1999 65(26):2791-9.
1998 Oct 19
Kusuhara M, Takahashi E, Peterson TE, Abe J, Ishida M, Han J, Ulevitch R, Berk BC. "p38 Kinase is a negative regulator of angiotensin II signal transduction in vascular smooth muscle cells: effects on Na+/H+ exchange and ERK1/2." Circulation research.. 1998 Oct 19; 83(8):824-31.
1998 Apr
Abe J, Deguchi J, Takuwa Y, Hara K, Ikari Y, Tamura T, Ohno M, Kurokawa K. "Tyrosine phosphorylation of platelet derived growth factor beta receptors in coronary artery lesions: implications for vascular remodelling after directional coronary atherectomy and unstable angina pectoris." Heart (British Cardiac Society). 1998 Apr; 79(4):400-6.
1997 Sep 16
Abe J, Deguchi J, Matsumoto T, Takuwa N, Noda M, Ohno M, Makuuchi M, Kurokawa K, Takuwa Y. "Stimulated activation of platelet-derived growth factor receptor in vivo in balloon-injured arteries: a link between angiotensin II and intimal thickening." Circulation.. 1997 Sep 16; 96(6):1906-13.
1997 Aug 15
Abe J, Takahashi M, Ishida M, Lee JD, Berk BC. "c-Src is required for oxidative stress-mediated activation of big mitogen-activated protein kinase 1." The Journal of biological chemistry.. 1997 Aug 15; 272(33):20389-94.
1997 Aug
Takahashi E, Abe J, Berk BC. "Angiotensin II stimulates p90rsk in vascular smooth muscle cells. A potential Na(+)-H+ exchanger kinase." Circulation research.. 1997 Aug; 81(2):268-73.
1996 Aug
Shiojima I, Ikari Y, Abe J, Ishizaka N, Maemura K, Kurihara H, Isshiki TA, Suma H, Saeki H, Hara K, Tamura T, Yamaguchi T. "Thrombotic occlusion of the coronary artery associated with accidental detachment of undeployed Palmaz-Schatz stent." Catheterization and cardiovascular diagnosis. 1996 Aug; 38(4):360-2.
1996 Jul 12
Abe J, Kusuhara M, Ulevitch RJ, Berk BC, Lee JD. "Big mitogen-activated protein kinase 1 (BMK1) is a redox-sensitive kinase." The Journal of biological chemistry.. 1996 Jul 12; 271(28):16586-90.
1994 Jul 1
Abe J, Zhou W, Takuwa N, Taguchi J, Kurokawa K, Kumada M, Takuwa Y. "A fumagillin derivative angiogenesis inhibitor, AGM-1470, inhibits activation of cyclin-dependent kinases and phosphorylation of retinoblastoma gene product but not protein tyrosyl phosphorylation or protooncogene expression in vascular endothelial cells." Cancer research.. 1994 Jul 1; 54(13):3407-12.
1994 Jan 14
Abe J, Zhou W, Taguchi J, Takuwa N, Miki K, Okazaki H, Kurokawa K, Kumada M, Takuwa Y. "Suppression of neointimal smooth muscle cell accumulation in vivo by antisense cdc2 and cdk2 oligonucleotides in rat carotid artery." Biochemical and biophysical research communications.. 1994 Jan 14; 198(1):16-24.
1994 Jan
Ishizaka N, Issiki T, Saeki F, Ishizaka Y, Ikari Y, Abe J, Soumitsu Y, Hashimoto H, Masaki K, Yamaguchi T. "Angiographic follow-up after successful percutaneous coronary angioplasty for chronic total coronary occlusion: experience in 110 consecutive patients." American heart journal.. 1994 Jan; 127(1):8-12.
1994
Taguchi J, Abe J, Ohno M, Schwartz SM, Kurokawa K. "Topical application of AT1 receptor antagonists prevents medial and neointimal proliferation after balloon injury." Blood pressure. Supplement. 1994 5:38-42.
1993 Oct 29
Taguchi J, Abe J, Okazaki H, Ochiai M, Ohno M, Takuwa Y, Kurokawa K. "Angiotensin converting enzyme inhibitors or DuP753 prevent neointimal formation following balloon injury with single topical or multiple systemic application." Biochemical and biophysical research communications.. 1993 Oct 29; 196(2):969-74.
1993 Aug
Abe J, Yamaguchi T, Isshiki T, Naka H, Taguchi J, Ishizaka N, Kurokawa K, Saeki F, Ishizaka Y, Ui K. "Myocardial reperfusion can be predicted by myoglobin/creatine kinase ratio of a single blood sample obtained at the time of admission." American heart journal.. 1993 Aug; 126(2):279-85.
1993
Taguchi J, Abe J, Okazaki H, Takuwa Y, Kurokawa K. "L-arginine inhibits neointimal formation following balloon injury." Life sciences.. 1993 53(23):PL387-92.
1992 Jun
Iihara K, Abe J, Murakami T. "Neuronal hyaline inclusions observed in an autopsy case of Behçet's disease." Acta pathologica japonica. 1992 Jun; 42(6):432-8.
1991 Nov 9
Abe J, Yamaguchi T, Isshiki T, Naka H, Kawada Y, Katayama Y. "Rapid quantitation of serum myoglobin by latex agglutination turbidimetry." Clinica chimica acta; international journal of clinical chemistry. 1991 Nov 9; 203(1):95-6.

Books

2001
Berk BC, Surapistchat J, Yoshizumi M, Yan C, Hoefen R, Abe J. "Atheroprotective mechanisms of fluid shear stress: Nitic oxidide independent inhibition of signal transduction mediated by inflammatory cytokines". Vascular endothelium Source and target of inflammatory Mediators, NATO Science S. : IOS Press, 2001. 115-125
2000
Abe, J., Yan C., Surapisitchat J, Berk BC. "Kinase Signaling in the Cardiovascular System". Heart Physiology and Pathophysiolog. : Academic Press, 2000. 657-677
2000
Abe, J., Berk BC. "Reactive Oxygen Species as Mediators of Signal Transduction in Cardiovascular Disease". Antioxidant and Cardiovascular Disease. : Kluwer Academic Publishers, 2000. 57-70