Dr. Abe received his M.D. from the University of Yamagata, Japan in 1987. He was a senior medical fellow as well as an Instructor in Cardiology/Medicine in The First Department of Medicine at the University of Tokyo, Japan from 1991 to 1994. He received his Ph.D. Cardiology/Medicine from University Tokyo in 1998. Before arriving at the University of Rochester Medical Center in 1999, Dr. Abe was an Acting Instructor in Department of Medicine, Cardiology Division at the University of Washington. His basic research was done in Yoh Takuwa's laboratory at the University of Tokyo, and Bradford C. Berk's laboratory at University of Washington where he characterized several growth factors and molecules in vascular remodeling.
As described above, Dr. Abe is a physician-scientist with a 7-year experience as a practicing cardiologist in Japan. Since arriving to the United States 17 years ago, he has devoted his academic career as a basic scientist focused on gaining a deeper understanding of cardiovascular diseases that plague the modern world. The major goal of his laboratory is to understand the molecular mechanisms of atherosclerosis formation and heart failure, and to determine the mechanistic underpinning on why diabetes significantly increases the risk of cardiac mortality. Dr. Abe's lab has focused on the role of the mitogen-activated protein kinase (MAP) family and have sought the mechanisms responsible for oxidative, hyperglycemia, and hypoxic injury to the vascular endothelium and the heart.
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