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Alicia H. Augustine, Ph.D.

Contact Information

Public Health Sciences
265 Crittenden Blvd.
Rochester, NY 14642

Office: (585) 275-2791
Fax: (585) 461-3554

Professional Bio

Alicia Augustine is the Associate Director for Research in the Center for Human Experimental Therapeutics (CHET) and a Research Assistant Professor in the Department of Community and Preventive Medicine. CHET carries out the mission of conducting hypothesis-driven, rigorously designed, initial investigations of novel therapeutic interventions for human diseases, and is the T1 Key Function within the Clinical and Translational Science Institute. In her role as Associate Director, Dr. Augustine is responsible for collaborative initiation and maintenance of research projects within CHET, as well as engaging with University of Rochester investigators regarding research design and implementation of early phase clinical studies.

Additional responsibilities include representation of CHET within the Clinical and Translational Science Institute and co-coordination/instruction of the Experimental Therapeutics course (PM488). Her primary research interests include pre-clinical experimentation and early-phase trial design.

Recent Journal Articles

2011 Nov
Clementi AH, Gaudy AM, Zimmers TA, Koniaris LG, Mooney RA. "Deletion of interleukin-6 improves pyruvate tolerance without altering hepatic insulin signaling in the leptin receptor-deficient mouse." Metabolism: clinical and experimental. 2011 Nov; 60(11):1610-9. Epub 2011 May 31.
2010
Gaudy AM, Clementi AH, Campbell JS, Smrcka AV, Mooney RA. "Suppressor of cytokine signaling-3 is a glucagon-inducible inhibitor of PKA activity and gluconeogenic gene expression in hepatocytes." The Journal of biological chemistry. 2010 285(53):41356-65. Epub 2010 Oct 26.
2009 Nov
Clementi AH, Gaudy AM, Rooijen NV, Pierce RH, Mooney RA. "Loss of Kupffer cells in diet-induced obesity is associated with increased hepatic steatosis, STAT3 signaling, and further decreases in insulin signaling." Biochimica et biophysica acta. 2009 Nov; 1792(11):1062-72. Epub 2009 Aug 20.
2005 Aug
Klover PJ, Clementi AH, Mooney RA. "Interleukin-6 depletion selectively improves hepatic insulin action in obesity." Endocrinology. 2005 Aug; 146(8):3417-27. Epub 2005 Apr 21.

Current Appointments

Research Assistant Professor (Part-Time) - Department of Public Health Sciences (SMD) - Primary
Research Assistant Professor (Part-Time) - Center for Human Experimental Therapeutics

Education

MS | Clinical Investigation | University of Rochester School of Medicine and Dentistry2011
PhD | Pathology | University of Rochester School of Medicine and Dentistry2009
BS | Biology | Delaware Valley College2002

Post-Doctoral Training & Residency

Post-doctoral fellow, Preventive Cardiology, University of Rochester School of Medicine and Dentistry 2011