Steven H. Bernstein, M.D.

Steven H. Bernstein, M.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 704
Rochester, NY 14642

Fax: (585) 273-1042
Administrative: (585) 275-4099

Journal Articles

Showing all 46 journal articles available.

2014 Jan 1
Friedberg JW, Mahadevan D, Cebula E, Persky D, Lossos I, Agarwal AB, Jung J, Burack R, Zhou X, Leonard EJ, Fingert H, Danaee H, Bernstein SH. "Phase II study of alisertib, a selective Aurora A kinase inhibitor, in relapsed and refractory aggressive B- and T-cell non-Hodgkin lymphomas." Journal of clinical oncology : official journal of the American Society of Clinical Oncology.. 2014 Jan 1; 32(1):44-50. Epub 2013 Sep 16.
2013 Oct
Solh M, Fisher RI, Goy A, de Vos S, Bernstein SH, Esseltine DL, Neuwirth R, Morrison VA. "Herpes zoster complicating bortezomib therapy of relapsed/refractory indolent B-cell and mantle cell lymphoma: an analysis of two phase II trials." Leukemia & lymphoma.. 2013 Oct; 54(10):2185-9. Epub 2013 Mar 08.
2013 Sep
Williams ME, Bernstein SH, Jares P, Kahl BS, Witzig TE, Gordon LI. "Recent advances in mantle cell lymphoma: report of the 2012 Mantle Cell Lymphoma Consortium Workshop." Leukemia & lymphoma.. 2013 Sep; 54(9):1882-90. Epub 2013 Mar 04.
2013 Feb
Longhi MS, Robson SC, Bernstein SH, Serra S, Deaglio S. "Biological functions of ecto-enzymes in regulating extracellular adenosine levels in neoplastic and inflammatory disease states." Journal of molecular medicine (Berlin, Germany). 2013 Feb; 91(2):165-72. Epub 2013 Jan 06.
2012 Apr 5
Bernstein SH, Venkatesh S, Li M, Lee J, Lu B, Hilchey SP, Morse KM, Metcalfe HM, Skalska J, Andreeff M, Brookes PS, Suzuki CK. "The mitochondrial ATP-dependent Lon protease: a novel target in lymphoma death mediated by the synthetic triterpenoid CDDO and its derivatives." Blood.. 2012 Apr 5; 119(14):3321-9. Epub 2012 Feb 08.
2005 Apr 1
Ray DM, Akbiyik F, Bernstein SH, Phipps RP. "CD40 engagement prevents peroxisome proliferator-activated receptor gamma agonist-induced apoptosis of B lymphocytes and B lymphoma cells by an NF-kappaB-dependent mechanism." The Journal of immunology : official journal of the American Association of Immunologists.. 2005 Apr 1; 174(7):4060-9.
2005 Mar 1
Ryan EP, Pollock SJ, Pollack SJ, Murant TI, Bernstein SH, Felgar RE, Phipps RP. "Activated human B lymphocytes express cyclooxygenase-2 and cyclooxygenase inhibitors attenuate antibody production." The Journal of immunology : official journal of the American Association of Immunologists.. 2005 Mar 1; 174(5):2619-26.
2005 Feb 1
Czuczman MS, Koryzna A, Mohr A, Stewart C, Donohue K, Blumenson L, Bernstein ZP, McCarthy P, Alam A, Hernandez-Ilizaliturri F, Skipper M, Brown K, Chanan-Khan A, Klippenstein D, Loud P, Rock MK, Benyunes M, Grillo-Lopez A, Bernstein SH. "Rituximab in combination with fludarabine chemotherapy in low-grade or follicular lymphoma." Journal of clinical oncology : official journal of the American Society of Clinical Oncology.. 2005 Feb 1; 23(4):694-704.
Lou, Q; Conway, Jr TF; Egilmez, NK; Bernstein, SH; Loyall, JL; Kelleher, Jr RJ; Bankert, RB. "B cell tumor vaccine enhanced by covalent attachment of immunoglobulin to surface proteins on dendritic cells". Clinical Immunology. 2005; ahead of print. Link
Ryan, EP; Pollack, SJ; Murant, TI; Bernstein, SH; Felgar, RE; Phipps RP. "Activated human B lymphocytes express cyclooxygenase-2 and cyclooxygenase inhibitors attenuate antibody production." Journal of Immunology. 2005; 5: 2619-26.
2004 Nov
Ray DM, Bernstein SH, Phipps RP. "Human multiple myeloma cells express peroxisome proliferator-activated receptor gamma and undergo apoptosis upon exposure to PPARgamma ligands." Clinical immunology : the official journal of the Clinical Immunology Society.. 2004 Nov; 113(2):203-13.
2004 Aug 1
Lou Q, Kelleher RJ, Sette A, Loyall J, Southwood S, Bankert RB, Bernstein SH. "Germ line tumor-associated immunoglobulin VH region peptides provoke a tumor-specific immune response without altering the response potential of normal B cells." Blood.. 2004 Aug 1; 104(3):752-9. Epub 2004 Mar 30.
Phipps, RP; Ryan, E; Bernstein, SH. "Inhibition of cyclooxygenase-2: a new targeted therapy for B-cell lymphoma". Leukemia Research. 2004; 2: 109-111. Link
Phillips, GL; Abboud, CN; Bernstein, SH; Friedberg, JW; Ifthikharuddin, JJ; Lancet, JE; Liesveld, JL; Spreng, E; Johnson, V; Chapman, M; Vesole, DH. "Phase I study for poor-prognosis lymphoma: augmentation of the "BEAM" regimen with escalating dose melphalan using amifostine cytoprotection and autologous hematopoietic stem cell transplantation - a preliminary report". Seminars in Oncology. 2004; 31(6 suppl 18): 203-213. Link
2003 Jan 1
Hess SD, Egilmez NK, Bailey N, Anderson TM, Mathiowitz E, Bernstein SH, Bankert RB. "Human CD4+ T cells present within the microenvironment of human lung tumors are mobilized by the local and sustained release of IL-12 to kill tumors in situ by indirect effects of IFN-gamma." The Journal of immunology : official journal of the American Association of Immunologists.. 2003 Jan 1; 170(1):400-12.
2002 May
Bernstein SH, Jusko WJ, Krzyzanski W, Nichol J, Wetzler M. "Pharmacodynamic modeling of thrombopoietin, platelet, and megakaryocyte dynamics in patients with acute myeloid leukemia undergoing dose intensive chemotherapy." Journal of clinical pharmacology. 2002 May; 42(5):501-11.
2002 Feb
Czuczman MS, Fallon A, Mohr A, Stewart C, Bernstein ZP, McCarthy P, Skipper M, Brown K, Miller K, Wentling D, Klippenstein D, Loud P, Rock MK, Benyunes M, Grillo-López AJ, Bernstein SH. "Rituximab in combination with CHOP or fludarabine in low-grade lymphoma." Seminars in oncology.. 2002 Feb; 29(1 Suppl 2):36-40.
2001 May
Khushalani NI, Bakri FG, Wentling D, Brown K, Mohr A, Anderson B, Keesler C, Ball D, Bernstein ZP, Bernstein SH, Czuczman MS, Segal BH, McCarthy PL. "Respiratory syncytial virus infection in the late bone marrow transplant period: report of three cases and review." Bone marrow transplantation.. 2001 May; 27(10):1071-3.
2001 Mar 1
Schiffer CA, Anderson KC, Bennett CL, Bernstein S, Elting LS, Goldsmith M, Goldstein M, Hume H, McCullough JJ, McIntyre RE, Powell BL, Rainey JM, Rowley SD, Rebulla P, Troner MB, Wagnon AH, . "Platelet transfusion for patients with cancer: clinical practice guidelines of the American Society of Clinical Oncology." Journal of clinical oncology : official journal of the American Society of Clinical Oncology.. 2001 Mar 1; 19(5):1519-38.
Sugano, M; Conway, TF; Kelleher, R; Sugiyama, Y; Egilmez, N; Chen, FA; Bankert, D; Bernstein, SH. "Human dendritic cells pulsed with autologous B-cell lymphoma (BCL) lysate elicit a tumor specific MHC-class II restricted T-cell response". Journal of Experimental and Clinical Cancer Research. 2001; 20(2): 145-152. Link
Simon, M; Hahn, T; Ford, LA; Anderson, B; Swinnich, D; Baer, MR; Bamrach, B; Bernstein, SH; Bernstein, ZP; Czuczman, MS; Slack, JL; Wetzler, M; Herzig, G; Schriber, J; McCarthy, PL Jr. "Retrospective multivariate analysis of hepatic veno-occlusive disease after blood or marrow transplantation: possible beneficial use of low molecular weight heparin". Bone Marrow Transplanation. 2001; 27(6): 627-633. Link
2000 Nov
Fields KK, Crump M, Bence-Bruckler I, Bernstein S, Williams S, Frankel S, Miller A, Demetri G, Nabholtz JM, Cruickshank S, Lill M. "Use of PEG-rHuMGDF in platelet engraftment after autologous stem cell transplantation." Bone marrow transplantation.. 2000 Nov; 26(10):1083-8.
2000 Jun
Benekli M, Anderson B, Wentling D, Bernstein S, Czuczman M, McCarthy P. "Severe respiratory depression after dimethylsulphoxide-containing autologous stem cell infusion in a patient with AL amyloidosis." Bone marrow transplantation.. 2000 Jun; 25(12):1299-301.
Alidina, A; Lawrence, D; Ford, L; Baer, M; Bambach, B; Bernstein, SH; Czuczman, M; Slack, J; Spangenthal, E; Wetzler, M; Barcos, M; Proulx, GM; Anderson, B; McCarthy, PJ. "Thiotepa associated cardiomyopathy during blood or marrow transplantation: associated with female gender and cardiac risk factors". Bone and Marrow Transplantation. 1999; 5: 322-327. Link
Proulx, GM; El-Agamawi, AY; Lee, RJ; Orner, JB; Czuczman, M; McCarthy, P; Bernstein, Z; Bernstein, Sh. "Primary non-Hodgkins lymphoma of bone: treatment and outcome". Radiology Oncology. 1999; 33: 9-14. Link
Bernstein SH, Fay J, Frankel S, Christiansen N, Baer MR, Jacobs C, Blosch C, Hanna R, Herzig G. "A phase I study of recombinant human soluble interleukin-1 receptor (rhu IL-1R) in patients with relapsed and refractory acute myeloid leukemia." Cancer chemotherapy and pharmacology. 1999 43(2):141-4.
1998 Aug
Wetzler M, Bernstein SH, Baumann H, Fries KM, Stewart C, Blumenson L, Baer MR, Herzig GP, Bloomfield CD, Slack JL. "Expression and function of the megakaryocyte growth and development factor receptor in acute myeloid leukemia blasts." Leukemia & lymphoma.. 1998 Aug; 30(5-6):415-31.
Bernstein, SH; Barnett, M; Cairo, M; Champlin, R; Cornetta, K; DiPersio, J; Fay, JW; Gells, G; Herzig, GP; Keating, A; Linker, C; Miller, K; Nademanee, A; Negrin, R; Rondon, G; Tricot, G; Vaughan, W; Vose, J; Wolff, S; Ashby, M; Cohen, R; Hellman, S; Watanabe, B; Stryker, S; Nash, R. "A multicenter observational study of platelet recovery and utilization amound recipients of myeloablative therapy and stem cell transplantation". Blood. 1998; 91: 3506-3517. Link
1997 Sep
Bernstein SH, Fay JP, Christiansen NP, Pinero L, Shah D, Stephan M, Herzig GP. "Sequential interleukin-3 and granulocyte-colony stimulating factor prior to and following high-dose etoposide and cyclophosphamide: a phase I/II trial." Clinical cancer research : an official journal of the American Association for Cancer Research.. 1997 Sep; 3(9):1519-26.
1997 Jul
Koczwara B, Spangenthal E, Bernstein SH. "The development of congestive cardiac failure in a patient with hairy cell leukemia treated with 2-chlorodeoxyadenosine." Leukemia & lymphoma.. 1997 Jul; 26(3-4):413-5.
1997 Jun
Wetzler M, Baer MR, Bernstein SH, Blumenson L, Stewart C, Barcos M, Mrózek K, Block AW, Herzig GP, Bloomfield CD. "Expression of c-mpl mRNA, the receptor for thrombopoietin, in acute myeloid leukemia blasts identifies a group of patients with poor response to intensive chemotherapy." Journal of clinical oncology : official journal of the American Society of Clinical Oncology.. 1997 Jun; 15(6):2262-8.
Bernstein SH, Eaves CJ, Herzig R, Fay J, Lynch J, Phillips GL, Christiansen N, Reece D, Ericson S, Stephan M, Kovalsky M, Hawkins K, Rasmussen H, Devos A, Herzig GP. "A randomized phase II study of BB-10010: a variant of human macrophage inflammatory protein-1alpha for patients receiving high-dose etoposide and cyclophosphamide for malignant lymphoma and breast cancer." British journal of haematology.. 1997 99(4):888-95.
1996 Oct
Bernstein SH, Christiansen NP, Fay JP, Brown R, Herzig R, Frankel S, Blumenson L, Herzig GP. "Granulocyte-macrophage colony-stimulating factor (GM-CSF) priming of high-dose etoposide and cyclophosphamide: a pilot trial." Experimental hematology.. 1996 Oct; 24(12):1363-8.
1996 Sep
Bernstein SH, Brunetto VL, Davey FR, Wurster-Hill D, Mayer RJ, Stone RM, Schiffer CA, Bloomfield CD. "Acute myeloid leukemia-type chemotherapy for newly diagnosed patients without antecedent cytopenias having myelodysplastic syndrome as defined by French-American-British criteria: a Cancer and Leukemia Group B Study." Journal of clinical oncology : official journal of the American Society of Clinical Oncology.. 1996 Sep; 14(9):2486-94.
1996 Apr
Fay JW, Bernstein SH. "Recombinant human interleukin-3 and granulocyte-macrophage colony-stimulating factor after autologous bone marrow transplantation for malignant lymphoma." Seminars in oncology.. 1996 Apr; 23(2 Suppl 4):22-7.
1996 Feb 15
Baer MR, Bernstein SH, Brunetto VL, Heinonen K, Mrózek K, Swann VL, Minderman H, Block AW, Pixley LA, Christiansen NP, Fay JW, Barcos M, Rustum Y, Herzig GP, Bloomfield CD. "Biological effects of recombinant human granulocyte colony-stimulating factor in patients with untreated acute myeloid leukemia." Blood.. 1996 Feb 15; 87(4):1484-94.
Greenberg, SJ; Choi, Y; Ballow, M; Du, TL; Ward, P; Rickert, MH; Frankel, S; Bernstein, SH; Brecher, M. "Profile of immunoglobulin heacy chain variable gene repertoires and highly selective detection of malignant clonotypes in acute lymphoblastic leukemia". Journal of Leukocyte Biology. 1995; 87: 856-864. Link
1994 Oct 1
Fay JW, Lazarus H, Herzig R, Saez R, Stevens DA, Collins RH, Piñeiro LA, Cooper BW, DiCesare J, Campion M. "Sequential administration of recombinant human interleukin-3 and granulocyte-macrophage colony-stimulating factor after autologous bone marrow transplantation for malignant lymphoma: a phase I/II multicenter study." Blood.. 1994 Oct 1; 84(7):2151-7.
1994 Oct
Stone RM, Bernstein SH, Demetri G, Facklam DP, Arthur K, Andersen J, Aster JC, Kufe D. "Therapy with recombinant human erythropoietin in patients with myelodysplastic syndromes." Leukemia research.. 1994 Oct; 18(10):769-76.
1992 Aug
Bernstein SH, Kufe DW. "Future of basic/clinical hematopoiesis research in the era of hematopoietic growth factor availability." Seminars in oncology.. 1992 Aug; 19(4):441-8.
Baer, MR; Frankel, SR; Christiansen, NP; Caligiuri, MA; Bernstein, SH; Bloomfield, CD; Herzig, GP. "High dose cytarabine, idarubicin and G-CSF therapy for de novo and secondary adult acute myeloid leukemia: a pilot study". Leukemia and Lymphoma. 1992; 7(Suppl 2): 8-10. Link
1991 Aug
Kharbanda S, Nakamura T, Stone R, Hass R, Bernstein S, Datta R, Sukhatme VP, Kufe D. "Expression of the early growth response 1 and 2 zinc finger genes during induction of monocytic differentiation." The Journal of clinical investigation.. 1991 Aug; 88(2):571-7.
1991 Jul 5
Bernstein SH, Sherman ML, Hass R, Nakamura T, Kharbanda S, Kufe DW. "Effects of hexamethylene bisacetamide on induction of monocytic differentiation of human U-937 myeloid leukemia cells." Biochemical pharmacology.. 1991 Jul 5; 42(2):403-7.
Bernstein SH, Kharbanda SM, Sherman ML, Stone RM, Kufe DW. "Inhibition of protein kinase C is associated with a decrease in c-myc expression in human myeloid leukemia cells." FEBS letters.. 1991 294(1-2):73-6.
Bernstein, SH; Kharbanda, SM; Sherman, ML; Sukhatme, VP; Kufe, DW. "Induction of the zinc finger encoding EGR-1 gene by granulocyte-macrophage colony stimulating factor in human U-937 monocytic leukemia cells: Regulation by a post-transcriptional mechanism mediated through a pertussis toxin sensitive G-protein". Cell, Growth and Differentiation. 1991; 2: 273-278. Link
Sherman, ML; Stone, RM; Datta, R; Bernstein, SH; Kufe, DW. "Transcriptional and post-transcrpitional regulation of c-jun expression during monocytic differentiation of human myeloid leukemic cells". Journal Biol Chem. 1990; 265: 3320-3323. Link


Stone, RM; Bernstein, SH. "Mast cell leukemia and other mast cell neoplasms". Cancer Medicine. Holland, JF; Frei, E; Bast, RC; Kufe, DW; Morton, DL; Weichselbaum, RR. Philidelphia: Lea and Febiger, 1997. 2829-2834
Stone, RM; Bernstein, SH. "Mast cell leukemia". Cancer Medicine. Holland, JF; Frei, E; Bast, RC; Kufe, DW; Morton, DL; Weichselbaum, RR. Philadelphia: Lea and Febiger, 1993. 2092-2096
Bernstein, SH. "Growth factors in the management of acute adult leukemia". Hematology/Oncology clinics of North America. : unknown, 1993. 225-274
Sherman, ML; Stone, RM; Datta, R; Kharbanda, SM; Bernstein, SH; Kufe, DW. "Regulation of c-jun expression by phorbol esters and tumor necrosis factor". Molecular and Cellular Biology of Cytokines. Oppenheim, JJ; Powanda, MC; Kluger, MJ; Dinarello, CA. New York: Wiley-Liss, Inc, 1990. 221-226