Jonathan W. Mink, M.D., Ph.D.

Jonathan W. Mink, M.D., Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 631
Rochester, NY 14642

Office: (585) 275-3669
Lab: (585) 275-0613
Administrative: (585) 275-4783
Fax: (585) 275-3683

Research Bio

My research program focuses on three areas. First is the function of the basal ganglia in normal control of movement and the pathophysiology of basal ganglia disorders characterized by abnormal involuntary movements. The basal ganglia are affected by many disorders beginning in childhood including cerebral palsy, CNS infections, metabolic disorders and other genetic conditions. It is well known that children with diseases involving the basal ganglia have abnormal body postures, slowing of movement, involuntary movements, or a combination of these abnormalities. However, the pathophysiology of these abnormalities is poorly understood. We have hypothesized that the basal ganglia normally act to select desired movement patterns and inhibit competing movements. Deranged basal ganglia output results in unwanted competing motor patterns or difficulty selecting desired motor patterns.



Second, is Juvenile Neuronal Ceroid Lipofuscinosis (Batten Disease), a neurodegenerative disease of childhood. Our research has focused on the natural history of the disease and is now pursuing potential disease modifying therapeutics.

Third, is the impact of Tourette Syndrome on children, their families, and the community.

An additional line of research involves the study of children with a degenerative neurological disorder called Batten Disease (aka Neuronal Ceroid Lipofuscinosis). We are investigating the natural history and rate of progression of neurological symptoms in this disorder.

Awards & Honors (National)

Compassionate Doctor Award | Patient's Choice 2011
Elected Faculty Member | Alpha Omega Alpha 2009 - Present
America's Top Doctors | Castle Connolly Medical Ltd. 2009 - Present
Teacher Recognition Award | American Academy of Neurology 2008
Patient's Choice Award | Patient's Choice 2008 - Present
Who's Who in America 2007 - Present
Best Doctors in America 2005 - Present
Fellow | American Academy of Neurology 2004 - Present
Fellow, American Neurological Association 2002 - Present
Derek Denny-Brown Neurological Scholar Award, American Neurological Association 2002
Fellow, American Academy of Pediatrics 2002 - Present

Awards & Honors (Local)

URMC Diversity Award | University of Rochester Medical Center 2013
Faculty Mentoring Award for Mentoring of Clinical Science Trainees | University of Rochester School of Medicine and Dentistry 2011
Commendation for Third Year Teaching | University of Rochester School of Medicine and Dentistry 2011
Neurology Faculty Teaching Award | Department of Neurology, University of Rochester 2005
St. Louis Children's Hospital Housestaff Teaching Award 1993
Irwin Levy Prize in Neurology, Washington University 1989
O'Leary Prize for Neuroscience Research, Washington University 1987
High Honors for Senior Thesis, Wesleyan University 1980
Walkley Prize for Psychology Research, Wesleyan University 1980

Recent Journal Articles

Showing the 5 most recent journal articles. 98 available »

2014 Feb
Adams HR, Rose K, Augustine EF, Kwon JM, Deblieck EA, Marshall FJ, Vierhile A, Mink JW, Nance MA. "Experience, knowledge, and opinions about childhood genetic testing in Batten disease." Molecular genetics and metabolism.. 2014 Feb; 111(2):197-202. Epub 2013 Nov 04.
2014
Black KJ, Snyder AZ, Mink JW, Tolia VN, Revilla FJ, Moerlein SM, Perlmutter JS. "Spatial reorganization of putaminal dopamine D2-like receptors in cranial and hand dystonia." PloS one. 2014 9(2):e88121. Epub 2014 Feb 10.
2013 Nov
Schulz A, Kohlschütter A, Mink J, Simonati A, Williams R. "NCL diseases - clinical perspectives." Biochimica et biophysica acta.. 2013 Nov; 1832(11):1801-6. Epub 2013 Apr 17.
2013 Nov
Mink JW. "Conversion disorder and mass psychogenic illness in child neurology." Annals of the New York Academy of Sciences.. 2013 Nov; 1304:40-4. Epub 2013 Oct 18.
2013 Oct
Augustine EF, Mink JW. "Enzyme replacement in neuronal storage disorders in the pediatric population." Current treatment options in neurology. 2013 Oct; 15(5):634-51.

Current Appointments

Frederick A. Horner, MD Endowed Professorship in Pediatric Neurology - Department of Neurology, Child Neurology (SMD)
Professor - Department of Neurology, Child Neurology (SMD) - Primary
Professor - Department of Neurobiology and Anatomy (SMD)

Specialties

Neurology with Special Qualifications in Child Neurology - American Board of Psychiatry and Neurology

Education

PhD | Neuroscience | Washington University1989
MD | Medicine | Washington University1989
MA | Psychology | Wesleyan University1981
BA | Biology - Psychology | Wesleyan University1980

Post-Doctoral Training & Residency

Fellowship in Pediatric Neurology at St Louis Children's Hospital07/01/1992 - 06/30/1994
Residency in Neurology at Barnes Hospital07/01/1991 - 06/30/1992
Internship in Pediatrics at St Louis Children's Hospital07/01/1989 - 06/30/1991