Research Bio
Research Interests-Methodological
Stochastic processes and their biological applications
Asymptotic theory
Mixed effects models
Mixture Models
Computational biology
Functional data
Research Interests-Collaborative
Cell and stem cell biology
Immunology
Cancer research
Flow cytometry
Radiation research
Pharmacokinetics, pharmacodynamics and toxicology
Image analysis
2011
Chen, R.; Hyrien, O. "Quasi- and pseudo-likelihood estimation for discretely observed Markov branching processes". Journal of Statistical Planning and Inference. 2011; 141(7): 2209-2227. |
2011
Chen, Y.; Pandya, K.; Hyrien, O.; Keng, P.; Smudzin, T.; Anderson, J.; Qazi, R.; Smith, B.; Watson, T.; Feins, R.; Johnstone, D. "Preclinical and pilot clinical study of decetaxel chemoradiation for stage III non-small cell lung cancer." International Journal of Radiation Oncology, Biology, Physics. 2011; 80(5): 1358-1364. |
2011
Chen, R.; Hyrien, O.; Mayer-Proschel, M.; Noble, M. "A composite likelihood approach to the analysis of longitudinal clonal data on multitype cellular systems under an age-dependent branching process." Biostatistics. 2011; 12(1): 173-191. |
2011
Zhang, H.; Travis, L.B.; Chen, R.; Hyrien, O.; Milano, M.T.; Newlands, S.D.; Chen, Y. "Impact of Radiotherapy on Laryngeal Cancer Survival: A Population-Based Study of 13,808 U.S. Patients". Cancer. 2011; Jul 19. doi: 10.1002/cncr.26357.. |
2011
Kaspler, P.; Chen, R.; Hyrien, O.; Jelveh, S.; Bristow, R.G.; Hill, R.P. "Biodosimetry using Radiation-Induced Micronuclei in Skin Fibroblasts". International Journal of Radiation Biology. 2011; 87(8): 824-838. |