Research Bio
Dr. Tang's Ph.D. research at the University of Texas MD Anderson Cancer Center involved tumor necrosis factor signal transduction and protein processing. From 1995-98 she served as a postdoctoral fellow, studying growth inhibition of glioma cells by antisense TGF-alpha. Since her residency at North Shore and her surgical pathology fellowship at Yale, she has focused on early breast carcinogenesis.
At Rochester, Dr. Tang was the recipient of an Empire Clinical Research Investigator Program (ECRIP) award to fund a study of molecular markers that may predict a subgroup of ductal carcinoma in situ (DCIS) with high risk of progression to invasive ductal carcinoma (IDC). DCIS is a heterogeneous group of lesions that accounts over 20% of breast carcinoma diagnosed annually which has a 14-53% chance of progression to IDC over a 10-year period.
She is currently working to identify a group of biomarkers that will predict a subset of breast tumors with a high risk of bone metastasis. She is using immunocytochemistry, a common and relatively inexpensive form of analysis, in the hope that her findings may be easily translated into clinical practice, allowing more aggressive treatment of tumors with greater risk of metastasis.
2012 Apr
Subik K, Shu L, Wu C, Liang Q, Hicks D, Boyce B, Schiffhauer L, Chen D, Chen C, Tang P, Xing L. "The ubiquitin E3 ligase WWP1 decreases CXCL12-mediated MDA231 breast cancer cell migration and bone metastasis." Bone. 2012 Apr 0; 50(4):813-23. Epub 2012 Jan 11. |
2011 Feb
Tang P, Wei B, Yang WJ, Liu YS, Bu H. "[Prognostic factors of breast cancer]." Zhonghua bing li xue za zhi Chinese journal of pathology. 2011 Feb 0; 40(2):73-6. |
2010 Nov
Tang P, Wang J, Hicks DG, Wang X, Schiffhauer L, McMahon L, Yang Q, Shayne M, Huston A, Skinner KA, Griggs J, Lyman G. "A lower Allred score for progesterone receptor is strongly associated with a higher recurrence score of 21-gene assay in breast cancer." Cancer investigation. 2010 Nov 0; 28(9):978-82. |
2009 Jun 22
Wang X, Ni J, Hsu CL, Johnykutty S, Tang P, Ho YS, Lee CH, Yeh S. "Reduced Expression of Tocopherol-Associated Protein (TAP/Sec14L2) in Human Breast Cancer." Cancer investigation. 2009 Jun 22; :1. Epub 2009 Jun 22. |
2009
Chuang C, Hicks DG, Berenson M, Kulkarni S, Tang P. "Benign inclusion of axillary lymph nodes: report of two cases and literature review." The breast journal. 2009 15(6):664-5. Epub 2009 Aug 17. |
