Professional Bio
Residency: Anatomic Pathology/Clinical Pathology, Brooklyn Hospital Medical Center, Chief Resident 1997-98. Fellowships in surgical pathology and cytopathology (New York University Medical Center), and in genitourinary pathology (University of Rochester Medical Center). Board certified in Anatomic and Clinical Pathology; Cytopathology.
Clinical interests include genitourinary pathology, gastrointestinal pathology, Cytopathology (endoscopic ultrasound-guided fine needle aspiration biopsy), and the rapid diagnosis of superficial palpable lesions by fine needle aspiration biopsy
Research Bio
I have three major areas of research interests: Genitourinary (GU) Pathology, Tissue Microarrays (TMA), and Fine Needle Aspiration Biopsy (FNA).
During my GU pathology fellowship, I became fascinated by the role of neuroendocrine cells in the benign and neoplastic prostate (see Neuroendocrine website). Subsequently, I decided to study the pathogenesis and characterization of a rare and aggressive form of prostate cancer called small cell carcinoma of the prostate (see Publications below).
At the same time, I was introduced to the construction and use of TMAs for translational and clinical research. Our GU Pathology section has constructed a prostate progression TMA and a kidney tumor prevalence TMA, which have proved very useful in translational research at our institution. We are currently constructing prognostic TMAs for both the prostate and esophagus.
As a cytopathologist, I am involved with improving the efficiency of both superficial palpable lesions and endoscopic ultrasound-guided FNAs of pancreatico-duodenal lesions through the use of novel site-specific antibody panels. Working closely with the Immunocytochemistry laboratory, I am currently evaluating various antibody panels for pancreatic carcinoma from material obtained by endoscopic ultrasound-guided FNA.
2012 Nov 9
Izumi K, Li Y, Ishiguro H, Zheng Y, Yao JL, Netto GJ, Miyamoto H. "Expression of UDP-glucuronosyltransferase 1A in bladder cancer: Association with prognosis and regulation by estrogen." Molecular carcinogenesis. 2012 Nov 9; Epub 2012 Nov 09. |
2012 Nov
Miyamoto H, Izumi K, Yao JL, Li Y, Yang Q, McMahon LA, Gonzalez-Roibon N, Hicks DG, Tacha D, Netto GJ. "GATA binding protein 3 is down-regulated in bladder cancer yet strong expression is an independent predictor of poor prognosis in invasive tumor." Human pathology. 2012 Nov 0; 43(11):2033-40. Epub 2012 May 18. |
2012 Nov
Izumi K, Li Y, Zheng Y, Gordetsky J, Yao JL, Miyamoto H. "Seminal plasma proteins in prostatic carcinoma: increased nuclear semenogelin I expression is a predictor of biochemical recurrence after radical prostatectomy." Human pathology. 2012 Nov 0; 43(11):1991-2000. Epub 2012 May 21. |
2012 Sep
Subik MK, Gordetsky J, Yao JL, di Sant'agnese PA, Miyamoto H. "Frozen section assessment in testicular and paratesticular lesions suspicious for malignancy: its role in preventing unnecessary orchiectomy." Human pathology. 2012 Sep 0; 43(9):1514-9. Epub 2012 Mar 08. |
2012 Jul
Tobis S, Knopf JK, Silvers C, Messing EM, Yao J, Rashid HH, Wu G, Golijanin D. "Robot-assisted and laparoscopic partial nephrectomy with near infrared fluorescence imaging." Journal of endourology / Endourological Society. 2012 Jul 0; 26(7):797-802. Epub 2012 Mar 02. |
