Michael D. Bulger, Ph.D.

Michael D. Bulger, Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 703
Rochester, NY 14642

Books

Journal Articles

Showing all 29 journal articles available.

2010 Mar 15
Bulger M, Groudine M. "Enhancers: the abundance and function of regulatory sequences beyond promoters." Developmental biology. 2010 Mar 15; 339(2):250-7. Epub 2009 Dec 16.
2009 Oct 15
Fromm G, de Vries C, Byron R, Fields J, Fiering S, Groudine M, Bender MA, Palis J, Bulger M. "Histone hyperacetylation within the beta-globin locus is context-dependent and precedes high-level gene expression." Blood.. 2009 Oct 15; 114(16):3479-88. Epub 2009 Aug 18.
2009 Oct
Fromm G, Bulger M. "A spectrum of gene regulatory phenomena at mammalian beta-globin gene loci." Biochemistry and cell biology = Biochimie et biologie cellulaire. 2009 Oct; 87(5):781-90.
2009 Feb
Yang SR, Yao H, Rajendrasozhan S, Chung S, Edirisinghe I, Valvo S, Fromm G, McCabe MJ, Sime PJ, Phipps RP, Li JD, Bulger M, Rahman I. "RelB is differentially regulated by IkappaB Kinase-alpha in B cells and mouse lung by cigarette smoke." American journal of respiratory cell and molecular biology.. 2009 Feb; 40(2):147-58. Epub 2008 Aug 07.
2008 Jun
Yang SR, Valvo S, Yao H, Kode A, Rajendrasozhan S, Edirisinghe I, Caito S, Adenuga D, Henry R, Fromm G, Maggirwar S, Li JD, Bulger M, Rahman I. "IKK alpha causes chromatin modification on pro-inflammatory genes by cigarette smoke in mouse lung." American journal of respiratory cell and molecular biology.. 2008 Jun; 38(6):689-98. Epub 2008 Jan 31.
2007 Mar 1
Hu X, Eszterhas S, Pallazzi N, Bouhassira EE, Fields J, Tanabe O, Gerber SA, Bulger M, Engel JD, Groudine M, Fiering S. "Transcriptional interference among the murine beta-like globin genes." Blood.. 2007 Mar 1; 109(5):2210-6. Epub 2006 Oct 31.
2006 Aug 15
Bender MA, Byron R, Ragoczy T, Telling A, Bulger M, Groudine M. "Flanking HS-62.5 and 3' HS1, and regions upstream of the LCR, are not required for beta-globin transcription." Blood.. 2006 Aug 15; 108(4):1395-401. Epub 2006 Apr 27.
2006 Feb 15
Kingsley PD, Malik J, Emerson RL, Bushnell TP, McGrath KE, Bloedorn LA, Bulger M, Palis J. ""Maturational" globin switching in primary primitive erythroid cells." Blood.. 2006 Feb 15; 107(4):1665-72. Epub 2005 Nov 01.
2006 Jan 15
Hu X, Bulger M, Bender MA, Fields J, Groudine M, Fiering S. "Deletion of the core region of 5' HS2 of the mouse beta-globin locus control region reveals a distinct effect in comparison with human beta-globin transgenes." Blood.. 2006 Jan 15; 107(2):821-6. Epub 2005 Sep 27.
2005 Jul
Yenerel MN, Sundell IB, Weese J, Bulger M, Gilligan DM. "Expression of adducin genes during erythropoiesis: a novel erythroid promoter for ADD2." Experimental hematology.. 2005 Jul; 33(7):758-66.
2005 Jun 10
Bulger M. "Hyperacetylated chromatin domains: lessons from heterochromatin." The Journal of biological chemistry.. 2005 Jun 10; 280(23):21689-92. Epub 2005 Apr 19.
2003 Aug
Bulger M, Schübeler D, Bender MA, Hamilton J, Farrell CM, Hardison RC, Groudine M. "A complex chromatin landscape revealed by patterns of nuclease sensitivity and histone modification within the mouse beta-globin locus." Molecular and cellular biology. 2003 Aug; 23(15):5234-44.
2003 Feb 4
Hu X, Bulger M, Roach JN, Eszterhas SK, Olivier E, Bouhassira EE, Groudine MT, Fiering S. "Promoters of the murine embryonic beta-like globin genes Ey and betah1 do not compete for interaction with the beta-globin locus control region." Proceedings of the National Academy of Sciences of the United States of America.. 2003 Feb 4; 100(3):1111-5. Epub 2003 Jan 13.
2002 Apr
Bulger M, Sawado T, Schübeler D, Groudine M. "ChIPs of the beta-globin locus: unraveling gene regulation within an active domain." Current opinion in genetics & development. 2002 Apr; 12(2):170-7.
2002
Bulger M, Groudine M. "TRAPping enhancer function." Nature genetics. 2002 32(4):555-6.
2001 Oct
Tyler JK, Collins KA, Prasad-Sinha J, Amiott E, Bulger M, Harte PJ, Kobayashi R, Kadonaga JT. "Interaction between the Drosophila CAF-1 and ASF1 chromatin assembly factors." Molecular and cellular biology. 2001 Oct; 21(19):6574-84.
2001 Jul 20
Nakagawa T, Bulger M, Muramatsu M, Ito T. "Multistep chromatin assembly on supercoiled plasmid DNA by nucleosome assembly protein-1 and ATP-utilizing chromatin assembly and remodeling factor." The Journal of biological chemistry.. 2001 Jul 20; 276(29):27384-91. Epub 2001 May 01.
2000 Feb
Bender MA, Bulger M, Close J, Groudine M. "Beta-globin gene switching and DNase I sensitivity of the endogenous beta-globin locus in mice do not require the locus control region." Molecular cell. 2000 Feb; 5(2):387-93.
2000
Bulger M, Bender MA, van Doorninck JH, Wertman B, Farrell CM, Felsenfeld G, Groudine M, Hardison R. "Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters." Proceedings of the National Academy of Sciences of the United States of America.. 2000 97(26):14560-5.
1999 Oct 1
Bulger M, Groudine M. "Looping versus linking: toward a model for long-distance gene activation." Genes & development. 1999 Oct 1; 13(19):2465-77.
1999 Apr 27
Bulger M, van Doorninck JH, Saitoh N, Telling A, Farrell C, Bender MA, Felsenfeld G, Axel R, Groudine M, von Doorninck JH. "Conservation of sequence and structure flanking the mouse and human beta-globin loci: the beta-globin genes are embedded within an array of odorant receptor genes." Proceedings of the National Academy of Sciences of the United States of America.. 1999 Apr 27; 96(9):5129-34.
1997 Jul 11
Ito T, Bulger M, Pazin MJ, Kobayashi R, Kadonaga JT. "ACF, an ISWI-containing and ATP-utilizing chromatin assembly and remodeling factor." Cell. 1997 Jul 11; 90(1):145-55.
1996 Nov
Tyler JK, Bulger M, Kamakaka RT, Kobayashi R, Kadonaga JT. "The p55 subunit of Drosophila chromatin assembly factor 1 is homologous to a histone deacetylase-associated protein." Molecular and cellular biology. 1996 Nov; 16(11):6149-59.
1996 Oct 4
Ito T, Tyler JK, Bulger M, Kobayashi R, Kadonaga JT. "ATP-facilitated chromatin assembly with a nucleoplasmin-like protein from Drosophila melanogaster." The Journal of biological chemistry.. 1996 Oct 4; 271(40):25041-8.
1996 Jun
Ito T, Bulger M, Kobayashi R, Kadonaga JT. "Drosophila NAP-1 is a core histone chaperone that functions in ATP-facilitated assembly of regularly spaced nucleosomal arrays." Molecular and cellular biology. 1996 Jun; 16(6):3112-24.
1996 Mar
Kamakaka RT, Bulger M, Kaufman PD, Stillman B, Kadonaga JT. "Postreplicative chromatin assembly by Drosophila and human chromatin assembly factor 1." Molecular and cellular biology. 1996 Mar; 16(3):810-7.
1995
Bulger M, Ito T, Kamakaka RT, Kadonaga JT. "Assembly of regularly spaced nucleosome arrays by Drosophila chromatin assembly factor 1 and a 56-kDa histone-binding protein." Proceedings of the National Academy of Sciences of the United States of America.. 1995 92(25):11726-30.
1994
Bulger M, Kadonaga JT. "Biochemical reconstitution of chromatin with physiological nucleosome spacing". Methods Mol. Genet. 1994; 5: 241-262. Link
1993 Sep
Kamakaka RT, Bulger M, Kadonaga JT. "Potentiation of RNA polymerase II transcription by Gal4-VP16 during but not after DNA replication and chromatin assembly." Genes & development. 1993 Sep; 7(9):1779-95.