Fabeha Fazal, Ph.D.

Fabeha Fazal, Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 850
Rochester, NY 14642

Office: (585) 275-9917
Fax: (585) 756-7780
Administrative: (585) 275-5948

Journal Articles

Showing all 15 journal articles available.

Fazal F, Bijli KM, Murrill M, Leonard A, Minhajuddin M, Anwar, KN, Finkelstein JN, Watterson DM, Rahman A. "Critical role of non-muscle myosin light chain kinase in thrombin-induced endothelial cell inflammation and lung PMN recruitment". PLOS ONE. 2013; .
Bijli KM, Fazal F, Rahman A. ". Regulation of RelA/65 and endothelial cell inflammation by proline-rich tyrosine kinase 2". Am J Respir Cell Mol Biol. 2012; 47: 660-668.
Yang L, Chen G, Mohanty S, Scott G, Fazal F, Rahman A, Begum S, Hynes R, Xu L. "GPR56 regulates VEGF production and angiogenesis during melanoma progression." Cancer Res. 2011; 71: 5558-5568.
Rahman A, Fazal F. "Blocking NF-?B: An Inflammatory Issue". Proc Am Thorac Soc. 2011; 8: 497-503.
Fazal, F.; Rahman, A. "Hug tightly and say goodbye: role of endothelial ICAM-1 in leukocyte transmigration." Antioxid Redox Signal. 2009; 11: 823-829.
Fazal, F.; Bijli, K.M.; Minhajuddin, M.; Rein, T.; Finkelstein, J.N.; Rahman, A. "Essential role of cofilin-1 in regulating thronbin-induced RelA/p65 nuclear translocation and ICAM-1 expressionin endothelial cells." J Biol Chem. 2009; 284: 21047-56.
Minhajuddin M, Bijli KM, Fazal F, Sassano A, Nakayama KI, Hay N, Platanias LC, Rahman A. "Protein kinase C gamma? and ?PI 3-kinase/Akt activate mammalian target of rapamycin to modulate NF-kappa beta activation and ICAM-1 expression in endothelial cells." J Biol Chem. 2009; 284: 4052-4061.
Bijli, K.M.; Fazal, F.; Minhajuddin,M.; McGrath, J.L. "Activation of Syk by PKC-gamma regulates thrombin-induced ICAM-1 expression in endotheial cells via tyrosine phosphorylationof RelA/p65." J Biol Chem. 2008; 283: 14674-14684.
Fazal F, Minhajuddin M, Bijli KM, McGrath JL, Rahman A. "Evidence for actin cytoskeleton-dependent and independent pathways for RelA/p65 nuclear translocation in endothelial cells." J Biol Chem (minor revision). 2007; .
Bijli KM, Minhajuddin M, Fazal F, OReilly, MA, Platanias, LC, Rahman A. "c-Src interacts with and phosphorylates RelA/p65 to promote thrombin-induced ICAM-1 expression in endothelial cells." Am J Physiol: Cell Mol Physiol. 2007; 292. Link
2005 Jul
Fazal F, Gu L, Ihnatovych I, Han Y, Hu W, Antic N, Carreira F, Blomquist JF, Hope TJ, Ucker DS, de Lanerolle P. "Inhibiting myosin light chain kinase induces apoptosis in vitro and in vivo." Molecular and cellular biology. 2005 Jul; 25(14):6259-66.
2005 May 1
Minhajuddin M, Fazal F, Bijli KM, Amin MR, Rahman A. "Inhibition of mammalian target of rapamycin potentiates thrombin-induced intercellular adhesion molecule-1 expression by accelerating and stabilizing NF-kappa B activation in endothelial cells." The Journal of immunology : official journal of the American Association of Immunologists. 2005 May 1; 174(9):5823-9.
Anwar KN, Fazal F, Malik AB, Rahman A. "RhoA/Rho-associated kinase pathway selectively regulates thrombin-induced intercellular adhesion molecule-1 expression in endothelial cells via activation of I kappa B kinase beta and phosphorylation of RelA/p65." The Journal of immunology : official journal of the American Association of Immunologists. 2004 173(11):6965-72.
2003 Mar
Nobe H, Nobe K, Fazal F, De Lanerolle P, Paul RJ. "Rho kinase mediates serum-induced contraction in fibroblast fibers independent of myosin LC20 phosphorylation." American journal of physiology. Cell physiology. 2003 Mar; 284(3):C599-606. Epub 2002 Oct 03.
1995 Jun 1
Adami C, Pooley J, Glomb J, Stecker E, Fazal F, Fleming JO, Baker SC. "Evolution of mouse hepatitis virus (MHV) during chronic infection: quasispecies nature of the persisting MHV RNA." Virology. 1995 Jun 1; 209(2):337-46.


Rahman A, Fazal F, Hadi SM. "Strand scission in DNA induced by dietary flavonoids: Role of Cu (II) and oxygen free radicals.". Glimpses in Plant Research XI: Medicinal Plants; New Vistas of Research [Part 2]. Govil JN, Singh VK, Hashmi S. New Delhi, India: Today and Tomorrow's Printers and Publishers, 1993. 361-370