Kim Tieu, Ph.D.

Kim Tieu, Ph.D.

Contact Information

Plymouth University
Peninsula Schools of Medicine & Dentistry
John Bull Bldg., Tamar Science Park
Research Way, Plymouth, Devon PL6 8BU

Journal Articles

Showing all 35 journal articles available.

2014 Mar
Tieu K, Xia XG. "Cytosolic PINK1 escapes from mitochondria to promote dendritic outgrowth." Journal of neurochemistry. 2014 Mar; 128(6):787-9. Epub 2013 Nov 22.
2013
Jin YN, Yu YV, Gundemir S, Jo C, Cui M, Tieu K, Johnson GV. "Impaired mitochondrial dynamics and Nrf2 signaling contribute to compromised responses to oxidative stress in striatal cells expressing full-length mutant huntingtin." PloS one. 2013 8(3):e57932. Epub 2013 Mar 01.
2012 Apr 17
Lovatt D, Xu Q, Liu W, Takano T, Smith NA, Schnermann J, Tieu K, Nedergaard M. "Neuronal adenosine release, and not astrocytic ATP release, mediates feedback inhibition of excitatory activity." Proceedings of the National Academy of Sciences of the United States of America. 2012 Apr 17; 109(16):6265-70. Epub 2012 Mar 15.
2012 Jan
Fujita T, Williams EK, Jensen TK, Smith NA, Takano T, Tieu K, Nedergaard M. "Cultured astrocytes do not release adenosine during hypoxic conditions." Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2012 Jan; 32(1):e1-7. Epub 2011 Oct 12.
2011 Sep
Tieu K. "A guide to neurotoxic animal models of Parkinson's disease." Cold Spring Harbor perspectives in medicine. 2011 Sep; 1(1):a009316.
2011
Rappold PM, Cui M, Chesser AS, Tibbett J, Grima JC, Duan L, Sen N, Javitch JA, Tieu K. "Paraquat neurotoxicity is mediated by the dopamine transporter and organic cation transporter-3." Proceedings of the National Academy of Sciences of the United States of America. 2011 108(51):20766-71. Epub 2011 Dec 05.
2011
Lim S, Chesser AS, Grima JC, Rappold PM, Blum D, Przedborski S, Tieu K. "D-?-hydroxybutyrate is protective in mouse models of Huntington's disease." PloS one. 2011 6(9):e24620. Epub 2011 Sep 12.
2010 Oct
Fang F, Christian WV, Gorman SG, Cui M, Huang J, Tieu K, Ballatori N. "Neurosteroid transport by the organic solute transporter OST?-OST?." Journal of neurochemistry. 2010 Oct; 115(1):220-33. Epub 2010 Aug 12.
2010 Oct
Rappold PM, Tieu K. "Astrocytes and therapeutics for Parkinson's disease." Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. 2010 Oct; 7(4):413-23.
2010 Jul
Goldman N, Chen M, Fujita T, Xu Q, Peng W, Liu W, Jensen TK, Pei Y, Wang F, Han X, Chen JF, Schnermann J, Takano T, Bekar L, Tieu K, Nedergaard M. "Adenosine A1 receptors mediate local anti-nociceptive effects of acupuncture." Nature neuroscience. 2010 Jul; 13(7):883-8. Epub 2010 May 30.
2010 Apr 9
Cui M, Tang X, Christian WV, Yoon Y, Tieu K. "Perturbations in mitochondrial dynamics induced by human mutant PINK1 can be rescued by the mitochondrial division inhibitor mdivi-1." The Journal of biological chemistry. 2010 Apr 9; 285(15):11740-52. Epub 2010 Feb 17.
2010 Jan 5
Vives-Bauza C, Zhou C, Huang Y, Cui M, de Vries RL, Kim J, May J, Tocilescu MA, Liu W, Ko HS, Magrané J, Moore DJ, Dawson VL, Grailhe R, Dawson TM, Li C, Tieu K, Przedborski S. "PINK1-dependent recruitment of Parkin to mitochondria in mitophagy." Proceedings of the National Academy of Sciences of the United States of America. 2010 Jan 5; 107(1):378-83. Epub 2009 Dec 04.
2009 May 12
Cui M, Aras R, Christian WV, Rappold PM, Hatwar M, Panza J, Jackson-Lewis V, Javitch JA, Ballatori N, Przedborski S, Tieu K. "The organic cation transporter-3 is a pivotal modulator of neurodegeneration in the nigrostriatal dopaminergic pathway." Proceedings of the National Academy of Sciences of the United States of America. 2009 May 12; 106(19):8043-8. Epub 2009 Apr 29.
2009 Mar
Ballatori N, Krance SM, Notenboom S, Shi S, Tieu K, Hammond CL. "Glutathione dysregulation and the etiology and progression of human diseases." Biological chemistry. 2009 Mar; 390(3):191-214.
2007
Zhou H, Falkenburger BH, Schulz JB, Tieu K, Xu Z, Xia XG. "Silencing of the Pink1 gene expression by conditional RNAi does not induce dopaminergic neuron death in mice." International journal of biological sciences. 2007 3(4):242-50. Epub 2007 Mar 05.
2006
Tieu,K.;. "Mitochondrial dysfunction and neurodegenerative disorders in the basal ganglia, in Recent Breakthroughs in Basal Ganglia Research (Bezard, E. ed), Nova Science Publishers, New York (2006). [Book chapter]". 2006; .
2005 Jul 13
Choi DK, Pennathur S, Perier C, Tieu K, Teismann P, Wu DC, Jackson-Lewis V, Vila M, Vonsattel JP, Heinecke JW, Przedborski S. "Ablation of the inflammatory enzyme myeloperoxidase mitigates features of Parkinson's disease in mice." The Journal of neuroscience : the official journal of the Society for Neuroscience. 2005 Jul 13; 25(28):6594-600.
2005
Perier C, Tieu K, Guégan C, Caspersen C, Jackson-Lewis V, Carelli V, Martinuzzi A, Hirano M, Przedborski S, Vila M. "Complex I deficiency primes Bax-dependent neuronal apoptosis through mitochondrial oxidative damage." Proceedings of the National Academy of Sciences of the United States of America. 2005 102(52):19126-31. Epub 2005 Dec 19.
2005
Przedborski,S.; Tieu,K.;. "Toxic Animal Models, in Neurodegenerative disease: neurobiology, pathogenesis and therapeutics (Beal , Lang, Ludoph eds.) Cambridge University Press (2005) 196-221. [Book chapter]". 2005; : 196-221.
2004 Aug
Przedborski S, Tieu K, Perier C, Vila M. "MPTP as a mitochondrial neurotoxic model of Parkinson's disease." Journal of bioenergetics and biomembranes. 2004 Aug; 36(4):375-9.
2004 Jul
Tieu K, Perier C, Vila M, Caspersen C, Zhang HP, Teismann P, Jackson-Lewis V, Stern DM, Yan SD, Przedborski S. "L-3-hydroxyacyl-CoA dehydrogenase II protects in a model of Parkinson's disease." Annals of neurology. 2004 Jul; 56(1):51-60.
2003 Sep
Tieu K, Perier C, Caspersen C, Teismann P, Wu DC, Yan SD, Naini A, Vila M, Jackson-Lewis V, Ramasamy R, Przedborski S. "D-beta-hydroxybutyrate rescues mitochondrial respiration and mitigates features of Parkinson disease." The Journal of clinical investigation. 2003 Sep; 112(6):892-901.
2003 Jun
Teismann P, Vila M, Choi DK, Tieu K, Wu DC, Jackson-Lewis V, Przedborski S. "COX-2 and neurodegeneration in Parkinson's disease." Annals of the New York Academy of Sciences. 2003 Jun; 991:272-7.
2003 Jun
Tieu K, Ischiropoulos H, Przedborski S. "Nitric oxide and reactive oxygen species in Parkinson's disease." IUBMB life. 2003 Jun; 55(6):329-35.
2003 May 13
Wu DC, Teismann P, Tieu K, Vila M, Jackson-Lewis V, Ischiropoulos H, Przedborski S. "NADPH oxidase mediates oxidative stress in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease." Proceedings of the National Academy of Sciences of the United States of America. 2003 May 13; 100(10):6145-50. Epub 2003 Apr 29.
2003 Apr 29
Teismann P, Tieu K, Choi DK, Wu DC, Naini A, Hunot S, Vila M, Jackson-Lewis V, Przedborski S. "Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration." Proceedings of the National Academy of Sciences of the United States of America. 2003 Apr 29; 100(9):5473-8. Epub 2003 Apr 17.
2003 Feb
Teismann P, Tieu K, Cohen O, Choi DK, Wu DC, Marks D, Vila M, Jackson-Lewis V, Przedborski S. "Pathogenic role of glial cells in Parkinson's disease." Movement disorders : official journal of the Movement Disorder Society. 2003 Feb; 18(2):121-9.
2003
Przedborski S, Jackson-Lewis V, Vila M, Wu DC, Teismann P, Tieu K, Choi DK, Cohen O. "Free radical and nitric oxide toxicity in Parkinson's disease." Advances in neurology. 2003 91:83-94.
2002 Oct 29
Dauer W, Kholodilov N, Vila M, Trillat AC, Goodchild R, Larsen KE, Staal R, Tieu K, Schmitz Y, Yuan CA, Rocha M, Jackson-Lewis V, Hersch S, Sulzer D, Przedborski S, Burke R, Hen R. "Resistance of alpha -synuclein null mice to the parkinsonian neurotoxin MPTP." Proceedings of the National Academy of Sciences of the United States of America. 2002 Oct 29; 99(22):14524-9. Epub 2002 Oct 10.
2002 Mar 1
Wu DC, Jackson-Lewis V, Vila M, Tieu K, Teismann P, Vadseth C, Choi DK, Ischiropoulos H, Przedborski S. "Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease." The Journal of neuroscience : the official journal of the Society for Neuroscience. 2002 Mar 1; 22(5):1763-71.
2002
Wu DC, Tieu K, Cohen O, Choi DK, Vila M, Jackson-Lewis V, Teismann P, Przedborski S. "Glial cell response: A pathogenic factor in Parkinson's disease." Journal of neurovirology. 2002 8(6):551-8.
2001 Aug
Vila M, Jackson-Lewis V, Guégan C, Wu DC, Teismann P, Choi DK, Tieu K, Przedborski S. "The role of glial cells in Parkinson's disease." Current opinion in neurology. 2001 Aug; 14(4):483-9.
2001
Tieu K, Ashe PC, Zuo DM, Yu PH. "Inhibition of 6-hydroxydopamine-induced p53 expression and survival of neuroblastoma cells following interaction with astrocytes." Neuroscience. 2001 103(1):125-32.
1999 Nov 1
Tieu K, Zuo DM, Yu PH. "Differential effects of staurosporine and retinoic acid on the vulnerability of the SH-SY5Y neuroblastoma cells: involvement of bcl-2 and p53 proteins." Journal of neuroscience research. 1999 Nov 1; 58(3):426-35.
1998 Jun
Yu PH, Zhang X, Zuo DM, Lai CT, Tieu K, Davis BA, Boulton AA. "Aliphatic N-methylpropargylamines as potential neurorescue agents." Restorative neurology and neuroscience. 1998 Jun; 12(2-3):113-8.