I completed my graduate work at the University of Cincinnati under the mentorship of Dr. David Butler, a leading expert in tendon and ligament injury and repair, and having later completed a post-doctoral fellowship with Dr. Farshid Guilak at Duke University, at one of the leading orthopaedic research laboratories in the country. In the Fall of 2004, I joined the faculty of the University of Rochester as an Assistant Professor in the Departments of Orthopaedics and Biomedical Engineering. My research focuses primarily on tissue engineering of load bearing connective tissues, including ligament and tendon, cartilage, and bone.
My research focuses primarily on Musculoskeletal Tissue Engineering with an emphasis on challenging clinical problems and translational solutions.
Our approach is to develop in vivo and in vitro models of musculoskeletal injury and clinically-translatable outcome measures to assess the efficacy of regenerative and tissue engineering solutions.
Current research projects include:
1. Tissue Engineering of Massive Bone Allograft Union
2. Allografts and Gdf5 Gene Therapy in Flexor Tendon Tissue Engineering
3. Modulating Stem Cell Differentiation using Novel Allograft Scaffolds for Cartilage Repair
4. Fashioning a Superficial Zone-Like Layer in Bioreactor-Cultivated Tissue Engineered Cartilage
5. Evaluating models of human musculoskeletal disease and trauma
Chen T, Hilton MJ, Brown EB, Zuscik MJ, Awad HA. "Engineering superficial zone features in tissue engineered cartilage." Biotechnology and bioengineering. 2013 May 0; 110(5):1476-86. Epub 2012 Dec 27.
2013 Apr 9
Chu JY, Chen T, Awad HA, Elfar J, Hammert WC. "Comparison of an All-Inside Suture Technique With Traditional Pull-Out Suture and Suture Anchor Repair Techniques for Flexor Digitorum Profundus Attachment to Bone." The Journal of hand surgery. 2013 Apr 9; Epub 2013 Apr 09.
Dhillon RS, Xie C, Tyler W, Calvi LM, Awad HA, Zuscik MJ, O'Keefe RJ, Schwarz EM. "PTH-enhanced structural allograft healing is associated with decreased angiopoietin-2-mediated arteriogenesis, mast cell accumulation, and fibrosis." Journal of bone and mineral research : the official journal of the
American Society for Bone and Mineral Research. 2013 Mar 0; 28(3):586-97.
2013 Feb 22
Inzana JA, Maher JR, Takahata M, Schwarz EM, Berger AJ, Awad HA. "Bone fragility beyond strength and mineral density: Raman spectroscopy predicts femoral fracture toughness in a murine model of rheumatoid arthritis." Journal of biomechanics. 2013 Feb 22; 46(4):723-30. Epub 2012 Dec 20.
Juneja SC, Schwarz EM, O'Keefe RJ, Awad HA. "Cellular and molecular factors in flexor tendon repair and adhesions: a histological and gene expression analysis." Connective tissue research. 2013 54(3):218-26. Epub 2013 Apr 15.