Kameshwar Singh, D.V.M.

Kameshwar Singh, D.V.M.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box EHSC
Rochester, NY 14642

Office: (585) 273-1179
Fax: (585) 276-0453

Journal Articles

Showing all 68 journal articles available.

2014 Mar
Gasiewicz TA, Singh KP, Bennett JA. "The Ah receptor in stem cell cycling, regulation, and quiescence." Annals of the New York Academy of Sciences.. 2014 Mar; 1310:44-50. Epub 2014 Feb 03.
2014 Jan 15
Singh KP, Bennett JA, Casado FL, Walrath JL, Welle SL, Gasiewicz TA. "Loss of aryl hydrocarbon receptor promotes gene changes associated with premature hematopoietic stem cell exhaustion and development of a myeloproliferative disorder in aging mice." Stem cells and development.. 2014 Jan 15; 23(2):95-106. Epub 2013 Oct 19.
2011 Oct
Casado FL, Singh KP, Gasiewicz TA. "Aryl hydrocarbon receptor activation in hematopoietic stem/progenitor cells alters cell function and pathway-specific gene modulation reflecting changes in cellular trafficking and migration." Molecular pharmacology.. 2011 Oct; 80(4):673-82. Epub 2011 Jul 26.
2011 May
Singh KP, Garrett RW, Casado FL, Gasiewicz TA. "Aryl hydrocarbon receptor-null allele mice have hematopoietic stem/progenitor cells with abnormal characteristics and functions." Stem cells and development.. 2011 May; 20(5):769-84. Epub 2010 Nov 09.
2010
Casado, F.L.; Singh, K.P.; Gasiewicz, T.A. "The aryl hydrocarbon receptor: Regulation of hematopoiesis and involvement in the progression of blood diseases." Blood Cell Mol. Dis.. 2010; 44: 199-206.
2010
Laiosa, M.D.; Mills, J.H.; Lai, Z.W.; Singh, K.P.; Middleton, F.A.; Gasiewicz, T.A.; Silverstone, A.E. "Identification of stage specific gene modulation during early thymocyte development by whole genome profiling analysis following aryl hydrocarbon receptor activation." Mol. Pharmacol.. 2010; 77: 773-783.
2009
Gasiewicz, T.A.; Singh, K.P.; Casado, F.L. "The aryl hydrocarbon receptor has an important role in regulation of hematopoiesis: Implications for benzene-induced hematopoietic toxicity." Cell Biol. Interact.. 2009; 184: 246-251.
2009
Singh, K.P.; Casado, F.L.; Opanashuk, L.A.; Gasiewicz, T.A. "The aryl hydrocarbon receptor has a normal function in the regulation of hematopoietic and other stem/progenitor cell populations." Biochemical. Pharmacol.. 2009; 77: 577-587.
2009
SIngh, K.P.; Wyman, A.; Casado, F.L.; Garrett, R.W.; Gasiewicz, T.A. "Treatment of mice with the Ah receptor agonist and human carcinogen dioxin results in altered number and function of hematopoietic stem cells." Carcinogenesis. 2009; 30: 11-19.
2006
Singh, K.P.; Gerard, H.C.; Hudson, A.P.; Boros, D.L. "Differential expression of collagen, MMP, TIMP and fibrogenic-cytokine genes in the granulomatous colon of Schistosoma mansoni-infected mice." Ann. Trop. Med. Parasitol.. 2006; 100: 611-620.
2005
Boros, D.L.; Singh, K.P.; Gerard, H.C.; Hudson, A.P.; White, S.L.; Cutroneo, K.R. "A novel nonsteroidal antifibrotic oligo decoy containing the TGF-B element found in the COL1A1 gene which regulates murine schistosomiasis liver fibrosis." J. Cell. Physiol.. 2005; 204: 370-374.
2005
Singh, K.P.; Geard, H.C.; Hudson, A.P.; Reddy, T.R.; Boros, D.L. "Retroviral Foxp3 gene transfer ameliorates liver granuloma pathology in Schistosoms mansoni infected mice." Immunology. 2005; 114: 410-417.
2004
Singh, K.P.; Gerard, H.C.; Hudson, A.P.; Boros, D.L. "Dynamics of collagen, MMP and TIMP gene expression during the granulomatous, fibrotic process induced by Schistosoma mansoni." Ann. Trop. Med. Parasitol.. 2004; 98: 581-593.
2004
Singh, K.P.; Gerard, H.C.; Hudson, A.P.; Boros, D.L. "Expression of matrix metalloproteinases and their inhibitors during the resorption of Schistosome egg-induced fibrosis in praziquantel-treated mice." Immunology. 2004; 111: 343-352.
2002
Loeffler, D.A.; Lundy, S.K.; Singh, K.P.; Gerald, H.C.; Hudson, A.P.; Boros, D.L. "Soluble egg antigen from Schistosoma mansoni induced angiogenesis-related processes by up-regulating vascular edothelial growth factor in human endothelial cells." J. Infec. Dis.. 2002; 185: 1650-1656.
2001
McCabe, Jr., M.J.; Singh, K.P.; Reiners, Jr., J.J. "Low level lead exposure in vitro strimulates the proliferation and expansion of alloantigen-reactive CD4 high T-cells." Toxicol. Appl. Pharmacol.. 2001; 177: 219-231.
2000
McCabe, Jr., M.J.; Singh, K.P.; Reddy, S.A.; Chelladurai, B.; Pounds, J.G.; Reinder, Jr., J.J.; States, J.C. "Sensitivity of Myelomonocytic leukemia cells to arsenite-induced cell cycle disruption, apoptosis, and enhanced differentiation is dependent on the inter-relationship between arsenic concentration, duration of treatment, and cell cycle phase." J. Pharmacol. Exptl. Therap.. 2000; 295: 724-733.
1999
McCabe, Jr., M.J.; Singh, K.P.; Reiners, Jr., J.J. "Lead intoxication impairs the generation of a delayed hypersensitivity response." Toxicology. 1999; 139: 255-264.
1997
Reiners, Jr., J.J.; Singh, K.P.; Yoon, H.L.; Conti, C.J. "Transplantation analyses of the immunogenicity of epidermal tumors generated in mouse skin two-stage carcinogenesis protocols." Mol. Carcinogenesis. 1997; 20: 48-57.
1997
Srivastava, A.K.; Singh, K.P.; Ray, P.K. "Protein A induced protection against experimental Candidiasis in mice." Mycopathologia. 1997; 138: 21-28.
1997
Reiners, Jr., J.J.; Singh, K.P. "Susceptibility of 129/Sv Ev mice in two-stage carcinogenesis protocol to 12-O-tetradecanoylphorbol-13-acetate promotion." Carcinogenesis. 1997; 18: 593-597.
1996
Yoon, H.L.; Singh, K.P.; Ratner, S.; Reiners, Jr., J.J. "Phorbol ester effects on splenic lymphocyte composition and cytotoxic T cell activities of SSIN mice: a strain deficient in CD 8+ T cells." Carcinogenesis. 1996; 17: 2617-2624.
1996
Singh, K.P.; Yoon, H.L.; Ratner, S.; Reiners, Jr., J.J. "Modulation of the development of humoral immunity by topically applied acetone, ethanol and 12-O- tetradecanoyl phorbol-13-acetate." Fundam. Appl. Toxicol.. 1996; 33: 129-139.
1995
Zaidi, S.I.A.; Singh, K.P.; Raisuddin, S.; Jafri, A.; Saxena, A.K.; Choudhary, S.; Ray, P.K. "Modulation of primary antibody response by protein A in tumor bearing mice." Immunopharmacol. Immunotoxicol.. 1995; 17: 759-773.
1994
Raisuddin, S.; Singh, K.P.; Zaidi, S.I.A.; Ray, P.K. "Immunomodulating effects of protein A in immunosuppressed aflatoxin-intoxicated rats." Int. J. Immunopharmacol.. 1994; 16: 977-984.
1994
Raisuddin, S.; Parmar, D.; Zaidi, S.I.A.; Singh, K.P.; Verma, A.S.; Seth, P.K.; Ray, P.K. "Aflatoxin induced depletion of activities of phase I biotransformation enzymes in growing rats." Eur. J. Drug Metab. Toxicokinet.. 1994; 19: 163-168.
1994
Zaidi, S.I.A.; Raisuddin, S.; Singh, K.P.; Jafri, A.; Hussain, R.; Hussain, M.M.; Mall, S.A.; Seth, P.K.; Ray, P.K. "Acrylamide induced immunosuppression in rats and its modulation by 6-MFA, an interferon inducer." Immunopharmacol. Immunotoxicol.. 1994; 16: 247-260.
1994
Zaidi, S.I.A.; Raisuddin, S.; Jafri, A.; Singh, K.P.; Ray, P.K. "Modulation of anti-sheep erythrocyte primary antibody response by protein A in normal mice." Immunopharmacol. Immunotoxicol.. 1994; 16: 85-96.
1993
Singh, K.P.; Gupta, R.K.; Shau, H.; Ray, P.K. "Effect of ASTA-Z 7575 (INN Maphosphamide) on human lymphokine-activated killer cell induction." Immunopharmacol. Immunotoxicol.. 1993; 15: 525-538.
1993
Raisuddin, S.; Singh, K.P.; Zaidi, S.I.A.; Paul, B.N.; Ray, P.K. "Immunosuppressive effects of aflatoxin in growing rats." Mycopathologia. 1993; 124: 189-194.
1993
Singh, K.P.; Gaur, A.; Chandra, H.; Ray, P.K. "Drinking water quality of Bankura district (West Bengal) as indicator of environmental pollution." Aquatic & Terrestrial Habitats. 1993; : 71-78.
1992
Singh, K.P.; Zaidi, S.I.A.; Raisuddin, S.; Saxena, A.K.; Murthy, R.C.; Ray, P.K. "Effect of zinc on immune functions and host resistance against infection and tumor challenge." Immunopharmocol. Immunotoxicol.. 1992; 14: 813-840.
1992
Singh, K.P.; Shau, H.; Kopald, K.; Gupta, R.K.; Ray, P.K. "Protein A potentiates lymphokine activated killer cell induction in normal and melanoma patient lymphocytes." Immunopharmacol. Immunotoxicol.. 1992; 14: 79-103.
1991
Mall, S.A.; Zaidi, S.I.A.; Husain, M.M.; Singh, K.P.; Mathur, N.; Gupta, B.M. "Protective effect of a fungal growth product (6-MFA) assessed therapeutically against Ehrlich's ascites tumor in Swiss mice." J. Biol. Regulators Homeostat. Agents. 1991; 5: 45-51.
1991
Raisuddin, S.; Zaidi, S.I.A.; Singh, K.P.; Ray, P.K. "Effect of subchronic aflatoxin exposure on growth and progression of Ehrlich's ascites tumor in mice." Drug and Chem. Toxicol.. 1991; 14: 185-206.
1991
Lindeman, R.A.; Singh, K.P.; Shau, H.; Gupta, R.K. "The effects of staphylococcal protein A on human lymphokine-activated killer cell induction." Cancer Immunol. Immunother.. 1991; 33: 97-102.
1991
Ray, P,K.; Singh, K.P.; Raisuddin, S.; Prasad, A.K. "Immunological responses to aflatoxins and other chemical carcinogens." J. Toxicol. Toxin Reviews. 1991; 10: 63-68.
1990
Zaidi, S.I.A.; Singh, K.P.; Raisuddin, S.; Saxena, A.K.; Ray, P.K. "Protein A induced abrogation of cyclophosphamide toxicity is associated with concomitant potentiation of immune function of host." Immunopharmacol. Immunotoxicol.. 1990; 12: 479-512.
1990
Raisuddin, S.; Singh, K.P.; Zaidi, S.I.A.; Saxena, A.K.; Ray, P.K. "Effect of aflatoxin on lymphoid cells of weanling rat." J. Appl. Toxicol.. 1990; 10: 245-250.
1990
Singh, K.P.; Zaidi, S.I.A.; Raisuddin, S.; Saxena, A.K.; Dwivedi, P.D.; Seth, P.K.; Ray, P.K. "Protection against carbon tetrachloride induced lymphoid organotoxicity by protein A in rat." Toxicol. Letters. 1990; 51: 339-351.
1990
Raisuddin, S.; Saxena, A.K.; Singh, K.P. "Aflatoxins in industry and industrial toxicology." Industr. Toxicol. Bull.. 1990; 12: 3-5.
1989
Dwivedi, P.D.; Verma, A.S.; Misra, A.; Singh, K.P.; Prasad, A.K.; Saxena, A.K.; Dutta, K.K.; Mathur, N.; Ray, P.K. "Protein A protects mice from depletion of biotransformation enzymes and mortality induced by Salmonella typhimurium endotoxin." Toxicol. Letters. 1989; 49: 1-13.
1988
Saxena, A.K.; Singh, K.P.; Dutta, K.K.; Gupta, G.S.D.; Nagale, S.L.; Misra, A.; Zaidi, S.I.A.; Ray, P.K. "Inhalation toxicity studies of methyl isocyanate (MIC) in rats: Part V. Immunologic response of rats two weeks after exposure, phagocytic response, endotoxin susceptibility, local lung immunity, mitogenic and DTH response." Ind. J. Exptl. Biol.. 1988; 26: 195-200.
1988
Saxena, A.K.; Singh, K.P.; Nagale, S.L.; Gupta, B.N.; Ray, P.K.; Srivastava, R.K.; Tiwari, S.P.; Singh, R. "Effect of exposure to toxic gas on the population of Bhopal. Part IV. Immunological and chromosomal studies." Ind. J. Exptl. Biol.. 1988; 26: 173-176.
1988
Sahu, A.P.; Upreti, R.K.; Singh, K.P. "Pathomorphologic evidence of modulation of coal-induced lesions by Jaggery in rats." Ind J. Med. Res.. 1988; 87: 308-317.
1988
Singh, K.P.; Saxena, A.K.; Zaidi, S.I.A.; Dwivedi, P.D.; Srivastava, S.P.; Seth, P.K.; Ray, P.K. "Protection against carbon tetrachloride induced hepatotoxicity by protein A in rats." J. Appl. Toxicol.. 1988; 8: 407-410.
1988
Khangarot, B.S.; Ray, P.K.; Singh, K.P. "Influence of copper treatment on the immune response in an air breathing teleost." Bull. Environ. Contam. Toxicol.. 1988; 41: 222-226.
1987
Srivastava, S.P.; Singh, K.P.; Saxena, A.K.; Seth, P.K.; Ray, P.K. "In vivo protection by protein A of hepatic microsomal mixed function oxidase system of CCl4 administered rats." Biochem. Pharmacol.. 1987; 36: 4055-4058.
1987
Prasad, A.K.; Singh, K.P.; Saxena, A.K.; Mathur, N.; Ray, P.K. "Increased macrophage activity in protein A treated tumor regressed animals." Immunopharmacol. Immunotoxicol.. 1987; 9: 541-561.
1987
Singh, K.P.; Saxena, A.K.; Prasad, A.K.; Dwivedi, P.D.; Zaidi, S.I.A.; Ray, P.K. "Effect of protein A on mast cell numbers and macrophage phagocytic activity." Immunopharmacol. Immunotoxicol.. 1987; 9: 281-289.
1987
Ray, P.K.; Saxena, A.K.; Singh, K.P. "Immunomodulation of host as a predictive bioindicator of toxicity in the mammalian system." Def. Sci. J.. 1987; 37: 245-255.
1986
Singh, K.P.; Upreti, R.K.; Saxena, A.K.; Shanker, R. "A comparative studies of thymic toxicity induced by 2,5-Hexanediol and 2,5-Hexanidione in weanling and adult rats." Ind. J. Exptl. Biol.. 1986; 24: 371-377.
1986
Upreti, R.K.; Singh, K.P.; Saxena, A.K.; Shanker, R. "Effect of 2,5-Hexanedione on lymphoid organs of rats: a preliminary report." Environ. Res.. 1986; 39: 188-198.
1986
Sahu, A.P.; Saxena, A.K.; Singh, K.P.; Shanker, R. "Effect of choline administration in rats." Ind. J. Exptl. Biol.. 1986; 24: 91-96.
1986
Singh, K.P.; Uppal. P.K. "Studies on the mycological examination of female genital tracts of buffalo." J. Rec. Adv. Appl. Sci. 1986; 1: 67-71.
1986
Singh K.P.; Uppal, P.K. "Studies on the mycological examination of buffalo semen." J. Rec. Adv. Appl. Sci.. 1986; 1: 86-88.
1986
Singh, K.P.; Uppal, P.K. "Isolation of Alternaria sp. From the genital tract of buffalo." J. Rec. Adv. Appl. Sci.. 1986; 1: 89-90.
1985
Sahu, A.P.; Singh, K.P.; Shukla, L.J.; Shanker, R. "Choline and mica dust induced pulmonary lesions in rats." Industrial Health. 1985; 23: 135-144.
1985
Kannan, K.; Singh, K.P.; Goel, S.K.; Shanker, R. "Effect of 2,5-Hexanediol on immunocompetence of mice." Environ. Res.. 1985; 36: 14-25.
1984
Singh, K.P.; Saxena, A.K.; Srivastava, S.N.; Shanker, R. "Effect of caffeine ( 1,3,7-trimethylxanthine ) on bone marrow cells of mice." Ind. J. Exptl. Biol.. 1984; 22: 608-611.
1984
Saxena, A.K.; Singh, K.P.; Srivastava, S.N.; Shukla, L.J.; Shanker, R. "Immunomodulating effects of caffeine in rodents." Ind. J. Exptl. Biol.. 1984; 22: 298-301.
1984
Rastogi, S.K.; Clerk. S.H.; Mathur, N.; Singh, K.P. "Lung function studies in flour mill." J. Environ. Biol.. 1984; 5: 231-240.
1984
Gupta, B.N.; Singh, K.P. "Production and distribution of fungal spores and their medical significance". Biol. Memoirs. 1984; 1: 120-125.
1983
Singh, K.P.; Kannan, K.; Goel, S.K.; Pandya, K.P.; Shanker, R. "2,5-Hexanediol induced thymic atrophy and lymphocytotoxicity in rats." Industrial Health. 1983; 21: 235-242.
1983
Gupta, B.N.; Singh, K.P. "Mycological studies in small flour mills." Biol. Memoirs. 1983; 8: 95-102.
1982
Singh, K.P.; Saxena, A.K.; Kannan, K.; Nagale, S.L.; Dogra, R.K.S.; Shanker, R. "Immune responses in mice exposed to coal mine dust." Ind. J. Exptl. Biol.. 1982; 20: 417-418.
1980
Nagale, S.L.; Singh, K.P.; Saxena, A.K.; Dogra, R.K.S. "Effect of coal mine dust on lymphoid organs in rats." Ind. J. Exptl. Biol.. 1980; 18: 1278-1281.
1978
Rastogi, S.K.; Singh, K.P. "Health hazards from cotton dust, a review." the Journal of Health Sci. AROGYA. 1978; 4: 84-91.

Books

1995
K.P. Singh and A.K. Srivastava. Chemical Pollution in Environment. New Delhi, India: Ashish Publication, 1995.
1995
Reiners, J.J.; Singh, K.P.. "Role of immunosurveillance and immunostimulation in the process of chemical carcinogenesis in murine skin.". Skin Cancer: mechanism and human relevance. Mukhtar, H.. Boca Raton, FL: CRC Press, 1995. 237-254
1992
K.G. Mukerji, A.K. Srivastava, K.P. Singh and K.L. Garg. Advances in Medical Mycology. : Aditya Book, 1992.
1992
Ray, P.K.; Singh, K.P.; Raisuddin, S.. "Aflatoxin and human health.". Advances in Medical Mycology. Mukerji, K.G.; Srivastava, A.K.; Singh, K.P.; Garg, K.L.. New Delhi, India: Aditya Books, 1992. 173-200
1992
Ray, P.K.; Srivastava, A.K.; Singh, K.P.. "Microbial degradation of pesticides-a biotechnological approach.". Environment and Biodegradation. Agrawal, V.P.; Rana, S.V.S.. Muzaffar Nagar, India: Society of Biosciences, 1992. 335-366
1987
Ray, P.K.; Singh, K.P.. "Immunotoxicologic studies and their potential.". Research in Industry. Mulky, M.J.; Srivastava, H.C.; Vatsya, B.. : Oxford and IBH Publishing Co. Pvt. Ltd., 1987. 168-178