Professional Bio
Dr. Lawrence Saubermann is a Gastroenterologist at Strong Memorial Hospital and Associate Professor of Medicine at the University of Rochester School of Medicine. He received a B.A. in Biology from Brandeis University, Waltham, Massachusetts. He attended medical school at the University of Texas, Southwestern Medical School in Dallas, Texas. He then completed his internship and residency in Internal Medicine at Rhode Island Hospital, and Brown University, in Providence, Rhode Island. Dr. Saubermann then completed a clinical and research fellowship in Gastroenterology at Brigham and Women’s Hospital, Harvard Medical School, in Boston, Massachusetts.
He was an Instructor in Medicine at the Brigham and Women’s hospital for a couple of years before moving to Boston University Medical Center to establish his independent research program. While at Boston University Medical Center, he became an Assistant Professor of Medicine, and stayed there for five years as a Staff Gastroenterologist. In July 2005, he came to Strong Memorial Hospital to continue his research and clinical activities in the area of Inflammatory Bowel Disease. He has received grants and published widely in this area, as well as written chapters in major textbooks. He enjoys teaching on the wards, in the clinics, and in the laboratory.
Research Bio
Dr. Saubermann is interested in the intestinal mucosal immune system, and how it is involved in Inflammatory Bowel Diseases, such as Crohn's Disease, Ulcerative Colitis, Microscopic/lymphocytic colitis, and Celiac Sprue. He has a number of projects related to inflammatory bowel disease, including clinical research trials with new biologic agents, testing for novel serologic markers of disease activity, and examining the effects of environmental toxins on the mucosal immune system. He is collaborating with other clinical and basic science researchers throughout the university to better understand the mechanisms behind the disease and develop new therapies. In addition, he participates as a co-investigator on a longitudinal countywide database study of inflammatory bowel disease subjects.
| CCFA Executive Board and CMAC | Rochester Chapter |
2010 |
| Fellowship in American College of Gastroenterology |
2009 |
| Chair of Education, Appointed Member | CCFA Medical Advisory Committee | Rochester, NY |
2008 |
| Senior Research Award
Crohn's and Colitis Foundation of America Senior Research Award |
2003 |
| Appointed Institutional Review Board Committee Member (Panel Purple, Active) |
2002 |
| Appointed Member of New England CCFA Medical Advisory Committee (Active) |
2002 |
| Broad Medical Research Program Award
Broad Foundation |
2002 |
| Appointed Institutional Review Board Committee Member (Panel Green, Active) |
2001 |
| Mentored Clinical Scientist Development Award (K08)
National Institutes of Health |
1998 |
| Physician Post-Doctoral Research Fellowship Award
Howard Hughes Medical Institute |
1998 |
| Mentored Clinical Scientist Development Award K08 | National Institiute of Health |
1998 |
| Astra-Merck Advanced Research Training Award
American Digestive Health Foundation |
1997 |
| cum laude
Brandeis University |
1987 |
2010 May
Zhang L; Sun W; Wang J; Zhang M; Yang S; Tian Y; Vidyasagar S; Pena LA; Zhang K; Cao Y; Yin L; Wang W; Zhang L; Schaefer KL; Saubermann LJ; Swarts SG; Fenton BM; Keng PC; Okunieff P. "Mitigation effect of an FGF-2 peptide on acute gastrointestinal syndrome after high-dose ionizing radiation". Int J Radiat Oncol Biol Phys. 2010; 77(1): 261-8. |
2010
Schaefer KL; Harris G; Jasalavich CA; Morales VM; Saubermann LJ. "PPAR gamma suppresses early phase but increases late phase production of IL-8 in TNFa-stimulated intestinal epithelial cells". To be submitted. 2010; . |
2008
Kobayashi N; Inamori M; Fujita K; Fujisawa T; Fujisawa N; Takahashi H; Yoneda M; Abe Y; Kawamura H; Shimamura T; Kirikoshi H; Kubota K; Sakaguchi T; Saito S; Saubermann LJ; Nakajima A. "Characterization of K-ras gene mutations in association with mucinous hypersecretion in intraductal papillary-mucinous neoplasms". J Hepatobiliary Pancreat Surg. 2008; 15(2): 169-77. |
2007 Feb 1
Schaefer KL, Takahashi H, Morales VM, Harris G, Barton S, Osawa E, Nakajima A, Saubermann LJ. "PPARgamma inhibitors reduce tubulin protein levels by a PPARgamma, PPARdelta and proteasome-independent mechanism, resulting in cell cycle arrest, apoptosis and reduced metastasis of colorectal carcinoma cells." International journal of cancer. Journal international du
cancer. 2007 Feb 1; 120(3):702-13. |
2007
Probert CS, Saubermann LJ, Balk S, Blumberg RS. "Repertoire of the alpha beta T-cell receptor in the intestine". Immunol Rev. 2007; 215: 215-25. |
