Oksana Polesskaya, Ph.D.

Oksana Polesskaya, Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 672
Rochester, NY 14642

Lab: (585) 275-2708

Journal Articles

Showing all 20 journal articles available.

2014 Oct
Silva JN, Polesskaya O, Wei HS, Rasheed IY, Chamberlain JM, Nishimura C, Feng C, Dewhurst S. "Chronic central nervous system expression of HIV-1 Tat leads to accelerated rarefaction of neocortical capillaries and loss of red blood cell velocity heterogeneity." Microcirculation : the official journal of the Microcirculatory Society, Inc. 2014 Oct; 21(7):664-76.
2014 Apr
Polesskaya O, Wong C, Lebron L, Chamberlain JM, Gelbard HA, Goodfellow V, Kim M, Daiss JL, Dewhurst S. "MLK3 regulates fMLP-stimulated neutrophil motility." Molecular immunology. 2014 Apr; 58(2):214-22. Epub 2014 Jan 03.
Lin F, Roiland R, Polesskaya O, Chapman B, Johnson M, Brasch J, Chen DG, Mapstone M. "Fatigability Disrupts Cognitive Processes' Regulation of Inflammatory Reactivity inĀ Old Age." The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. 2014 22(12):1544-54. Epub 2013 Dec 07.
2013 Oct 24
Goodfellow VS, Loweth CJ, Ravula SB, Wiemann T, Nguyen TX, Xu Y, Todd DE, Sheppard DW, Pollack S, Polesskaya O, Marker DF, Dewhurst S, Gelbard HA. "Discovery, synthesis, and characterization of an orally bioavailable, brain penetrant inhibitor of mixed lineage kinase 3." Journal of medicinal chemistry. 2013 Oct 24; 56(20):8032-48. Epub 2013 Oct 03.
Polesskaya O, Sun A, Salahura G, Silva JN, Dewhurst S, Kasischke K. "Detection of microregional hypoxia in mouse cerebral cortex by two-photon imaging of endogenous NADH fluorescence." Journal of visualized experiments : JoVE. 2012 (60)Epub 2012 Feb 21.
Silva J, Polesskaya O, Knight W, Zheng JT, Granger M, Lopez T, Ontiveros F, Feng C, Yan C, Kasischke KA, Dewhurst S. "Transient hypercapnia reveals an underlying cerebrovascular pathology in a murine model for HIV-1 associated neuroinflammation: role of NO-cGMP signaling and normalization by inhibition of cyclic nucleotide phosphodiesterase-5." Journal of neuroinflammation. 2012 9:253. Epub 2012 Nov 20.
2011 Feb 10
Polesskaya O, Silva J, Sanfilippo C, Desrosiers T, Sun A, Shen J, Feng C, Polesskiy A, Deane R, Zlokovic B, Kasischke K, Dewhurst S. "Methamphetamine causes sustained depression in cerebral blood flow." Brain research. 2011 Feb 10; 1373:91-100. Epub 2010 Dec 13.
2010 Oct 20
Perry SW, Barbieri J, Tong N, Polesskaya O, Pudasaini S, Stout A, Lu R, Kiebala M, Maggirwar SB, Gelbard HA. "Human immunodeficiency virus-1 Tat activates calpain proteases via the ryanodine receptor to enhance surface dopamine transporter levels and increase transporter-specific uptake and Vmax." The Journal of neuroscience : the official journal of the Society for Neuroscience. 2010 Oct 20; 30(42):14153-64.
2010 Oct
Gelbard HA, Dewhurst S, Maggirwar SB, Kiebala M, Polesskaya O, Gendelman HE. "Rebuilding synaptic architecture in HIV-1 associated neurocognitive disease: a therapeutic strategy based on modulation of mixed lineage kinase." Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. 2010 Oct; 7(4):392-8.
Polesskaya O, Cunningham LL, Francis SP, Luebke AE, Zhu X, Collins D, Vasilyeva ON, Sahler J, Desmet EA, Gelbard HA, Maggirwar SB, Walton JP, Frisina RD, Dewhurst S. "Ablation of mixed lineage kinase 3 (Mlk3) does not inhibit ototoxicity induced by acoustic trauma or aminoglycoside exposure." Hearing research. 2010 270(1-2):21-7. Epub 2010 Oct 27.
2008 Apr 9
Paletzki RF, Myakishev MV, Polesskaya O, Orosz A, Hyman SE, Vinson C. "Inhibiting activator protein-1 activity alters cocaine-induced gene expression and potentiates sensitization." Neuroscience. 2008 Apr 9; 152(4):1040-53. Epub 2008 Feb 07.
Myakishev M, Polesskaya O, Kulichkova V, Baranova A, Gause L, Konstantinova I. "PCR-based detection of Pol III-transcribed transposons and its application to the rodent model of ultraviolet response." Cell stress & chaperones. 2008 13(1):111-6. Epub 2008 Feb 13.
2007 Jan 1
Polesskaya OO, Smith RF, Fryxell KJ. "Chronic nicotine doses down-regulate PDE4 isoforms that are targets of antidepressants in adolescent female rats." Biological psychiatry. 2007 Jan 1; 61(1):56-64. Epub 2006 Jun 30.
Polesskaya OO, Fryxell KJ, Merchant AD, Locklear LL, Ker KF, McDonald CG, Eppolito AK, Smith LN, Wheeler TL, Smith RF. "Nicotine causes age-dependent changes in gene expression in the adolescent female rat brain." Neurotoxicology and teratology. 2007 29(1):126-40. Epub 2006 Nov 23.
2006 Feb 15
Polesskaya OO, Aston C, Sokolov BP. "Allele C-specific methylation of the 5-HT2A receptor gene: evidence for correlation with its expression and expression of DNA methylase DNMT1." Journal of neuroscience research. 2006 Feb 15; 83(3):362-73.
2005 Apr 5
Liu QR, Walther D, Drgon T, Polesskaya O, Lesnick TG, Strain KJ, de Andrade M, Bower JH, Maraganore DM, Uhl GR. "Human brain derived neurotrophic factor (BDNF) genes, splicing patterns, and assessments of associations with substance abuse and Parkinson's Disease." American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. 2005 Apr 5; 134B(1):93-103.
2003 Oct 1
Polesskaya OO, Haroutunian V, Davis KL, Hernandez I, Sokolov BP. "Novel putative nonprotein-coding RNA gene from 11q14 displays decreased expression in brains of patients with schizophrenia." Journal of neuroscience research. 2003 Oct 1; 74(1):111-22.
2003 Apr
Mir AA, Myakishev MV, Polesskaya OO, Moitra J, Petersen D, Miller L, Orosz A, Vinson C. "A search for candidate genes for lipodystrophy, obesity and diabetes via gene expression analysis of A-ZIP/F-1 mice." Genomics. 2003 Apr; 81(4):378-90.
2003 Jan
Sokolov BP, Polesskaya OO, Uhl GR. "Mouse brain gene expression changes after acute and chronic amphetamine." Journal of neurochemistry. 2003 Jan; 84(2):244-52.
2002 Mar 15
Polesskaya OO, Sokolov BP. "Differential expression of the "C" and "T" alleles of the 5-HT2A receptor gene in the temporal cortex of normal individuals and schizophrenics." Journal of neuroscience research. 2002 Mar 15; 67(6):812-22.