Joshua L. Allen, Ph.D.

Joshua L. Allen, Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box EHSC
Rochester, NY 14642

Research Bio

Dr. Allen is a Research Assistant Professor in the Department of Environmental Medicine. As a BIRCWH Scholar, his research will focus on how early life and in utero exposures to ambient air pollutants, including ultrafine particles, adversely affect the central nervous system. He aims to clarify the role of such exposures in the etiology of neurodevelopmental disorders, such as autism. He first became interested neurotoxicology as an undergraduate at Ashland University and continued to pursue those interests during his graduate work in toxicology at the University of Rochester School of Medicine and Dentistry.

His dissertation unveiled persistent, sex-dependent neurotoxicity as a result of developmental exposure to human-relevant levels of concentrated ambient ultrafine particles in rodents. Through interactions with environmental epidemiologists while completing his graduate training, Dr. Allen developed an interest in translating his animal model research to human studies, utilizing an epidemiological approach to assess air pollutant-induced neurotoxicity, particularly for neurodevelopmental disorders. He aims to continue to increase the understanding of the role of air pollution in neurotoxicity using both basic neurotoxicological and epidemiological approaches.

Awards & Honors (Local)

Robert Infurna Award for best research paper as first author in peer-reviewed journal, 2013 2013
Society of Toxicology Graduate Student Travel Award, 2011 2011
Ashland University Outstanding Undergraduate of the Year, 2007 2007

Recent Journal Articles

Showing the 5 most recent journal articles. 9 available »

2014 Jul 1
Allen JL, Liu X, Weston D, Prince L, Oberdörster G, Finkelstein JN, Johnston CJ, Cory-Slechta DA. "Developmental exposure to concentrated ambient ultrafine particulate matter air pollution in mice results in persistent and sex-dependent behavioral neurotoxicity and glial activation." Toxicological sciences : an official journal of the Society of Toxicology.. 2014 Jul 1; 140(1):160-78. Epub 2014 Apr 01.
2014 Jun 5
Allen JL, Liu X, Pelkowski S, Palmer B, Conrad K, Oberdörster G, Weston D, Mayer-Pröschel M, Cory-Slechta DA. "Early Postnatal Exposure to Ultrafine Particulate Matter Air Pollution: Persistent Ventriculomegaly, Neurochemical Disruption, and Glial Activation Preferentially in Male Mice." Environmental health perspectives.. 2014 Jun 5; Epub 2014 Jun 05.
2014 Mar
Allen JL, Liu X, Weston D, Conrad K, Oberdörster G, Cory-Slechta DA. "Consequences of developmental exposure to concentrated ambient ultrafine particle air pollution combined with the adult paraquat and maneb model of the Parkinson's disease phenotype in male mice." Neurotoxicology.. 2014 Mar; 41:80-8. Epub 2014 Jan 30.
2014 Mar
Weston HI, Sobolewski M, Allen JL, Weston D, Conrad K, Pelkowski S, Watson GE, Zareba G, Cory-Slechta DA. "Sex-dependent and non-monotonic enhancement and unmasking of methylmercury neurotoxicity by prenatal stress." Neurotoxicology.. 2014 Mar; 41:123-40. Epub 2014 Feb 03.
2013 Apr
Cory-Slechta DA, Weston D, Liu S, Allen JL. "Brain hemispheric differences in the neurochemical effects of lead, prenatal stress, and the combination and their amelioration by behavioral experience." Toxicological sciences : an official journal of the Society of Toxicology.. 2013 Apr; 132(2):419-30. Epub 2013 Jan 28.

Current Appointments

Research Assistant Professor - Department of Environmental Medicine (SMD) - Primary

Education

PhD | Toxicology | University of Rochester School of Medicine & Dentistry2013
MS | Molecular Toxicology & Env Medicine | University of Rochester School of Medicine & Dentistry2010
BS | Toxicology | Ashland University2003