Kate G. Ackerman, M.D.

Kate G. Ackerman, M.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 703
Rochester, NY 14642

Office: (585) 276-4001
Lab: (585) 276-4238
Fax: (585) 276-0232

Lab Information

Ackerman Lab

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Research Bio

Congenital Diaphragmatic Hernia (CDH) is a relatively common birth defect that results in a high rate of neonatal illness or death. The focus of Dr. Ackerman's laboratory is to identify genes that are necessary for development of the diaphragm and the lung.
Current research projects include:



- To identify mechnisms and pathway genes in Fog2 mediated diaphragm development and Fog2 mediated pulmonary lobar braching

-To investigate mechanisms of development in Barx1 homeobox gene associated posterior medical diaphragmatic hernia.

_To develop models for conditional deletion of genes on mesenchymal tissue of the diaphragm

-To develop new models of abnormal diaphragm and lung development from forward genetic screening

-To characterize human diaphragmatic defects and translate findings in animal models to the human disease with the hopes of modulating outcome in fetuses and neonates with congenital diaphragmatic defects

Awards & Honors (Local)

Henry C. and Bertha H. Buswell Fellow | University of Rochester 2008 - 2009
Harvard Medical School Leadership Development for Physicians and Scientists | Harvard Medical School 2006
Children's Hospital Faculty Development Award/Eleanor and Miles Shore Scholar | Harvard Medical School 2005
Children's Hospital Fellow Research Award | Harvard Medical School 2002
Glascow Award | University at Buffalo School of Medicine 1995
Association of Pathology Chairs Honor Society | University at Buffalo School of Medicine 1995
Honors and Distinction in Research | University at Buffalo School of Medicine 1995
Thesis Honors | University at Buffalo School of Medicine 1995
Honors Poster Award | University at Buffalo School of Medicine 1992
Dean's Letters of Commendation | University at Buffalo School of Medicine 1991 - 1995

Recent Journal Articles

Showing the 5 most recent journal articles. 16 available »

2013 May 21
Coles GL, Ackerman KG. "Kif7 is required for the patterning and differentiation of the diaphragm in a model of syndromic congenital diaphragmatic hernia." Proceedings of the National Academy of Sciences of the United States of America.. 2013 May 21; 110(21):E1898-905. Epub 2013 May 06.
2012
Ackerman KG, Vargas SO, Wilson JM, Jennings RW, Kozakewich HP, Pober B. "Congenital diaphragmatic defects: proposal for a new classification based on observations in 234 patients." Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society. 2012 15(4):265-74. Epub 2012 Mar 07.
2010
Kantarci S, Ackerman KG, (co-first authors Russell M, Longoni M, Sougnez C, Noonan KM, Hatchwell E, Zhang X, Canmarcke, RP,Anyane-Yeboe K, Dickman P, Wilson J, Donahue P, Pober BR). "Characterization of the Chromosome 1q41q42.12 region and the Candidate Gene DISP1, in Patients with CDH". American Journal of Medical Genetics. 2010; . Link
2009 Feb
Stevens TP, van Wijngaarden E, Ackerman KG, Lally PA, Lally KP, . "Timing of delivery and survival rates for infants with prenatal diagnoses of congenital diaphragmatic hernia." Pediatrics.. 2009 Feb; 123(2):494-502.
2009
Liu, X.; Ramjiganesh, T.; Chen, Y.H.; Chung, S.W.; Hall, S.R.; Schissel, S.L.; Padera, R.F. Jr.; Liao, R.; Ackerman, K.G.; Kajstura, J.; Leri, A.; Anversa, P.; Yet, S.F.; Layne, M.D.; Perrella M.A. "Disruption of striated preferentially expressed gene locus leads to dilated cardiomyopathy in mice." Circulation. 2009; 119(2): 261-268. Link

Current Appointments

Associate Professor - Department of Pediatrics, Critical Care (SMD) - Primary
Associate Professor - Department of Biomedical Genetics (SMD)

Specialties

Pediatrics - American Board of Pediatrics
Pediatric Critical Care Medicine - American Board of Pediatrics

Education

MD | Medicine | State University of New York at Buffalo, School of Medicine & Biomedical Sciences1995
BS | Biology | Cornell University1991

Post-Doctoral Training & Residency

Fellowship in Pediatric Critical Care Medicine at Children's Hospital Boston07/01/1998 - 06/30/2001
Residency in Pediatrics at Children s Hospital07/01/1996 - 06/30/1998
Internship in Pediatrics at Children s Hospital07/01/1995 - 06/30/1996