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Lata Balakrishnan, Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 672
Rochester, NY 14642

Lab: (585) 275-0999

Journal Articles

Showing all 26 journal articles available.

2014 Aug 13
Ngo GH, Balakrishnan L, Dubarry M, Campbell JL, Lydall D. "The 9-1-1 checkpoint clamp stimulates DNA resection by Dna2-Sgs1 and Exo1." Nucleic acids research.. 2014 Aug 13; Epub 2014 Aug 13.
2013 Feb
Balakrishnan L, Bambara RA. "Okazaki fragment metabolism." Cold Spring Harbor perspectives in biology. 2013 Feb; 5(2)Epub 2013 Feb 01.
Balakrishnan L, Bambara RA. "Flap endonuclease 1." Annual review of biochemistry.. 2013 82:119-38. Epub 2013 Feb 28.
Kallestad L, Woods E, Christensen K, Gefroh A, Balakrishnan L, Milavetz B. "Transcription and replication result in distinct epigenetic marks following repression of early gene expression." Frontiers in genetics. 2013 4:140. Epub 2013 Jul 30.
2012 Aug 30
Kantartzis A, Williams GM, Balakrishnan L, Roberts RL, Surtees JA, Bambara RA. "Msh2-Msh3 interferes with Okazaki fragment processing to promote trinucleotide repeat expansions." Cell reports. 2012 Aug 30; 2(2):216-22. Epub 2012 Aug 02.
2012 Aug
Gloor JW, Balakrishnan L, Campbell JL, Bambara RA. "Biochemical analyses indicate that binding and cleavage specificities define the ordered processing of human Okazaki fragments by Dna2 and FEN1." Nucleic acids research.. 2012 Aug; 40(14):6774-86. Epub 2012 May 07.
2012 Jun 1
Milavetz B, Kallestad L, Gefroh A, Adams N, Woods E, Balakrishnan L. "Virion-mediated transfer of SV40 epigenetic information." Epigenetics : official journal of the DNA Methylation Society.. 2012 Jun 1; 7(6):528-34. Epub 2012 Jun 01.
2012 Mar 1
Miller A, Balakrishnan L, Buncher NA, Opresko PL, Bambara RA. "Telomere proteins POT1, TRF1 and TRF2 augment long-patch base excision repair in vitro." Cell cycle.. 2012 Mar 1; 11(5):998-1007. Epub 2012 Mar 01.
2011 Aug 15
Balakrishnan L, Bambara RA. "The changing view of Dna2." Cell cycle.. 2011 Aug 15; 10(16):2620-1. Epub 2011 Aug 15.
2011 Jul 8
Fortini BK, Pokharel S, Polaczek P, Balakrishnan L, Bambara RA, Campbell JL. "Characterization of the endonuclease and ATP-dependent flap endo/exonuclease of Dna2." The Journal of biological chemistry.. 2011 Jul 8; 286(27):23763-70. Epub 2011 May 13.
2011 Mar 4
Balakrishnan L, Bambara RA. "Eukaryotic lagging strand DNA replication employs a multi-pathway mechanism that protects genome integrity." The Journal of biological chemistry.. 2011 Mar 4; 286(9):6865-70. Epub 2010 Dec 21.
2010 Nov 5
Gloor JW, Balakrishnan L, Bambara RA. "Flap endonuclease 1 mechanism analysis indicates flap base binding prior to threading." The Journal of biological chemistry.. 2010 Nov 5; 285(45):34922-31. Epub 2010 Aug 25.
2010 Oct
Balakrishnan L, Milavetz B. "Decoding the histone H4 lysine 20 methylation mark." Critical reviews in biochemistry and molecular biology. 2010 Oct; 45(5):440-52.
2010 Sep 10
Henry RA, Balakrishnan L, Tan Ying-Lin S, Campbell JL, Bambara RA. "Components of the secondary pathway stimulate the primary pathway of eukaryotic Okazaki fragment processing." The Journal of biological chemistry.. 2010 Sep 10; 285(37):28496-505. Epub 2010 Jul 13.
2010 Jul
Balakrishnan L, Gloor JW, Bambara RA. "Reconstitution of eukaryotic lagging strand DNA replication." Methods : a companion to Methods in enzymology.. 2010 Jul; 51(3):347-57. Epub 2010 Feb 21.
2010 Apr 1
Balakrishnan L, Gefroh A, Milavetz B. "Histone H4 lysine 20 mono- and tri-methylation define distinct biological processes in SV40 minichromosomes." Cell cycle.. 2010 Apr 1; 9(7):1320-32.
2010 Feb 12
Balakrishnan L, Stewart J, Polaczek P, Campbell JL, Bambara RA. "Acetylation of Dna2 endonuclease/helicase and flap endonuclease 1 by p300 promotes DNA stability by creating long flap intermediates." The Journal of biological chemistry.. 2010 Feb 12; 285(7):4398-404. Epub 2009 Dec 17.
Balakrishnan L, Polaczek P, Pokharel S, Campbell JL, Bambara RA. "Dna2 exhibits a unique strand end-dependent helicase function." The Journal of biological chemistry.. 2010 285(50):38861-8. Epub 2010 Oct 06.
2009 May 29
Balakrishnan L, Brandt PD, Lindsey-Boltz LA, Sancar A, Bambara RA. "Long patch base excision repair proceeds via coordinated stimulation of the multienzyme DNA repair complex." The Journal of biological chemistry.. 2009 May 29; 284(22):15158-72. Epub 2009 Mar 27.
Balakrishnan L, Milavetz B. "Dual agarose magnetic (DAM) ChIP." BMC research notes. 2009 2:250. Epub 2009 Dec 14.
Balakrishnan L, Milavetz B. "HDAC inhibitors stimulate viral transcription by multiple mechanisms." Virology journal. 2008 5:43. Epub 2008 Mar 19.
2007 Aug 24
Balakrishnan L, Milavetz B. "Histone hyperacetylation during SV40 transcription is regulated by p300 and RNA polymerase II translocation." Journal of molecular biology.. 2007 Aug 24; 371(4):1022-37. Epub 2007 Jul 03.
2007 Jan 5
Balakrishnan L, Milavetz B. "Histone hyperacetylation in the coding region of chromatin undergoing transcription in SV40 minichromosomes is a dynamic process regulated directly by the presence of RNA polymerase II." Journal of molecular biology.. 2007 Jan 5; 365(1):18-30. Epub 2006 Sep 20.
2006 Feb 5
Balakrishnan L, Milavetz B. "Reorganization of RNA polymerase II on the SV40 genome occurs coordinately with the early to late transcriptional switch." Virology.. 2006 Feb 5; 345(1):31-43. Epub 2005 Oct 20.
Balakrishnan L, Clauson R, Weiland T, Bianco M, Milavetz B. "Sexually transmitted Human Papillomavirus type variations resulting in high grade cervical dysplasia in North-East North Dakota and North-West Minnesota." Virology journal. 2006 3:46. Epub 2006 Jun 15.
2005 Mar 30
Balakrishnan L, Milavetz B. "Programmed remodeling of hyperacetylated histone H4 and H3 organization on the SV40 genome during lytic infection." Virology.. 2005 Mar 30; 334(1):111-23.