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Le Zhang, Ph.D.

Contact Information

University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 630
Rochester, NY 14642

Office: (585) 275-4212

Journal Articles

Showing all 31 journal articles available.

2014
Zhang, L.; Xue, Y.; Jiang, B.; Strouthos, C.; Wu, YK.; Duan, Z.; Su, J.; Zhou, X.;. "Multiscale agent-based modeling of ovarian cancer progression under the stimulation of the STAT 3 pathway". 2014; 9(3): 9.
2013
Wang, J.; Zhang, L.; Jing, C.; Ye, G.; Wu, H.; Miao, H.; Wu, Y.; Zhou, X.;. "Multi-scale agent-based modeling on melanoma and its related angiogenesis analysis". 2013; 10: 41. Link
2012
Sun, X.; Su, J.; Bao, J.; Peng, T.; Zhang, L.; Zhang, Y.; Yang, Y.; Zhou, X.;. "Cytokine combination therapy prediction for bone remodeling in tissue engineering based on the intracellular signaling pathway". 2012; 33(33): 8265-76. Link
2012
Sun, X.; Zhang, L.; Tan, H.; Bao, J.; Strouthos, C.; Zhou, X.;. "Multi-scale agent-based brain cancer modeling and prediction of TKI treatment response: Incorporating EGFR signaling pathway and angiogenesis". 2012; 13: 218. Link
2011
Jiang, B.; Struthers, A.; Sun, Z.; Feng, Z.; Zhao, X.; Dai, W.; Zhao, K.; Zhou, X.; Berens, M.; Zhang, L.;. "Employing graphics processing unit technology, alternating direction implicit method and domain decomposition to speed up the numerical diffusion solver for the biomedical engineering research". 2011; 27(11): 20.
2011
Jiang, B.; Zhang, L.; Zhang, W.; Struthers, A.; Berens, M.; Zhou, X.;. "Accelerate numerical diffusion solver of 2D multiscale and multi-resolution agent-based brain cancer model by employing graphics processing unit technology". 2011; : 523-528..
2011
Wu, YK.; Zhang, L.;. "Review and comparison of two academic software packages for analyzing 2D Gel images". 2011; 9(6): 775-794.
2011
Zhang, L.; Jiang, B.; Wu, Y.; Strouthos, C.; Sun, P. Z.; Su, J.; Zhou, X.;. "Developing a multiscale, multi-resolution agent-based brain tumor model by graphics processing units". 2011; 8: 46. Link
2010
Zhang, L.; Chen, B.; Jiang, B.;. "A Novel Bayesian classification system integrated with mobile agent based modeling technology". 2010; .
2010
Zhang, L.; Zhong, G.; Wu, Y.; Vangel, M.; Jiang, B.; Kong, J.;. "Using granger-geweke causality model to evaluate the effective connectivity of primary motor cortex, supplementary motor area and cerebellum". 2010; 3: 848-860.
2009
Deisboeck, T. S.; Zhang, L.; Yoon, J.; Costa, J.;. "In silico cancer modeling: is it ready for prime time?". 2009; 6(1): 34-42. Link
2009
Zhang, L.; Chen, L. L.; Deisboeck, T. S.;. "Multi-scale, multi-resolution brain cancer modeling". 2009; 79(7): 14.
2009
Zhang, L.; Strouthos, C. ; Wang, Z.; Deisboeck, T. S.;. "Simulating brain tumor heterogeneity with a multiscale agent-based model: Linking molecular signatures, phenotypes and expansion rate". 2009; 49(1-2): 307-319.
2009
Zhang, L.; Wang, Z.; Sagotsky, J. A.; Deisboeck, T. S.;. "Multiscale agent-based cancer modeling". 2009; 58(4-5): 545-59. Link
2008
Chen, L. L.; Zhang, L.; Yoon, J.; Deisboeck, T. S.;. "Cancer cell motility: Optimizing spatial search strategies". 2008; . Link
2008
Sagotsky, J. A.; Zhang, L.; Wang, Z.; Martin, S.; Deisboeck, T. S.;. "Life Sciences and the web: a new era for collaboration". 2008; 4: 201. Link
2007
Deisboeck, T. S.; Zhang, L.; Martin, S.;. "Advancing cancer systems biology: introducing the Center for the Development of a Virtual Tumor, CViT". 2007; 5: 1-8. Link
2007
Wang, Z.; Zhang, L.; Sagotsky, J.; Deisboeck, T. S.;. "Simulating non-small cell lung cancer with a multiscale agent-based model". 2007; 4: 50. Link
2007
Zhang, L.; Athale, C. A.; Deisboeck, T. S.;. "Development of a three-dimensional multiscale agent-based tumor model: simulating gene-protein interaction profiles, cell phenotypes and multicellular patterns in brain cancer". 2007; 244(1): 96-107. Link
2007
Zhang, L.; Dai, W.; Nassar, R.;. "A numerical algorithm for obtaining an optimal temperature distribution in a 3D triple-layered cylindrical skin structure". 2007; 14: 107-125.
2006
Dai, W.; Bejan, A.; Tang, X.; Zhang, L.; Nassar, R.;. "Optimal temperature distribution in a 3D triple layered skin structure with embedded vasculature". 2006; 99(10): 104702-9.
2006
Zhang, L.; Dai, W.; Nassar, R.;. "A numerical method for obtaining an optimal temperature distribution in a 3D triple-layered cylindrical skin structure embedded with a blood vessel". 2006; 49: 765-784.
2005
Dai, W.; Zhang, L.; Zhu, T.;. "Numerical modeling for optimizing laser power irradiating on a 3D triple layered skin structure". 2005; .
2005
Zhang, L.; Dai, W.; Nassar, R.;. "A numerical method for optimizing laser power in the irradiation of a 3D triple layered cylindrical skin structure". 2005; 48: 21-41.
2004
Zhang, L.; Tang, X.; Dai, W.;. "High dimension Web cluster algorithm". 2004; .
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Jiang, B.; Dai, W.; Khaliq, A.; Wu, Y.; Su, J.; Zhou, X.; Zhang, L.;. "Accelerating 3D diffusion model in a cylindrical coordinate system by graphics processing unit (GPU) techniques". .
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Peng, T.; Zhang, L.;. "Characterization of p38 MAPK Isoforms for Drug Resistance Study Using Systems Biology Approach". .
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Qiao, M.; Zhang, L.; Wu, D.; Carey, M.; Zhou, X.;. "Multi-scale agent-based multi myeloma cancer modeling and the investigation of the balance mechanism between osteoclasts and osteoblasts". .
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Shi, L.; Huang, Z.; Zhang, L.;. "Integrating Semantic Query function into D-NetWeaver". .
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Su, J.; Zhang, L.;. "Targeting the Biophysical Properties of the Myeloma Initiating Cell Niches: A Pharmaceutical Synergism Analysis Using Multi-scale Agent-based Modeling". .
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Wang, J.; Zhang, L.;. "Association studies on mtDNA and Parkinson’s disease population discrimination using the statistical classification". .

Books