Spring 2012, Department of Pharmacology and Physiology and Cellular and Molecular Pharmacology and Physiology Colloquium Series

The weekly colloquium is generally held on Thursdays at 12:30 p.m. in the Anders Conference Room (4-6912). Unless otherwise noted, our departmental colloquia program is supported by the Alejandro Zaffaroni Endowment Fund and the John R. Murlin Fund.

January 11, 2012

Nicole M. Boschi

(Graduate Student in the Laboratory of Dr. A. William Tank)

“The Subcellular Localization of Poly(c)-Binding Proteins (PCBPs) to Processing Bodies in Catecholaminergic Cell Lines”

January 12, 2012

Pui Yee Chan

(Graduate student in the laboratory of Dr. Gregory G. Tall)
“Deciphering the Role of Cellular Chaperones and Ric-8 Proteins in G Protein Alpha Subunit Biosynthesis”

January 19, 2012

Meital Gabay

(Graduate student in the laboratory of Dr. Gregory G. Tall)
“Ric-8 Proteins are Molecular Chaperones that Direct Nascent G Protein Alpha Subunit Membrane Association”

January 20, 2012- Thesis Proposal

Alex F. Fricke

(Graduate student in the laboratory of Dr. David I. Yule)
“Contribution of the Two Pore Channel to Shaping the Physiological & Pathological Ca2+ Signaling in the Exocrine Pancreas”

January 26, 2012

Eric M. Small, Ph.D.

Assistant Professor of Medicine in the Cardiovascular Research Institute, University of Rochester Medical Center
“Molecular Mechanisms Regulating Cardiovascular Remodeling”

(Guest of Dr. Robert S. Freeman)

February 9, 2012

Erik L. Allman

(Graduate student in the laboratory of Dr. Keith Nehrke)
“Integrated Calcium and Proton Signaling During a Rhythmic Behavior in C. elegans: Regulation of Na+/H+ Exchanger NHX-7”

February 16, 2012

Michael Sellix, Ph.D.

Assistant Professor, Division of Endocrinology and Metabolism, University of Rochester Medical Center

“A Circadian Egg Timer: How the Other “Biological Clock ” Regulates Reproductive Physiology”

(Guest of Dr. A. William Tank)

February 23, 2012

Laura B. Fornarola

(Graduate student in the laboratory of Dr. Robert S. Freeman)
“The Role of Pin1 in Neuronal Programmed Cell Death Following Trophic Factor Deprivation”

March 1, 2012

Wei W. Kan

(Graduate student in the laboratory of Dr. Alan V. Smrkca)
“Regulation of Phospholipase C beta Activation via Direct Binding to Intracellular Loops of the M3 Muscarinic Acetylcholine Receptor”

March 20, 2012

Oded N. Spindel

(Graduate student in the laboratory of Dr. Bradford C. Berk)

“Thioredoxin Interacting Protein (TXNIP): Regulator of Plasma Membrane Signaling in Endothelial Cells”

March 22, 2012

Shey-Shing Sheu, Ph.D.

Professor in the Center for Translational Medicine, Department of Medicine, Jefferson Medical College, Thomas Jefferson University

“Pathophysiological Significance of Multiple Mitochondrial Ca2+ Influxes Mechanisms: With a Specific Focus on Mitochondrial Ryanodine Receptor”

(Guest of Dr. Robert T. Dirksen)

March 29, 2012

Roberto Weigert, Ph.D.

Chief, Intracellular Membrane Trafficking Unit, Oral and Pharyngeal Cancer Branch, National Institute of Dental & Craniofacial Research (NIDCR), National Institutes of Health

“Intravital Microscopy a Powerful Tool to Study Membrane Trafficking (and more....) in Live Animals”

(Guest of Dr. David I. Yule)

April 3, 2012

Yelena V. Lerman

(Graduate student in the laboratory of Dr. Minsoo Kim)

“Integrin α3β1 Upregulation on Neutrophils: A Biomarker of Bacterial Sepsis”

April 5, 2012 - Paul Stark Lecture

Gary Landreth, Ph.D.

Professor of Neurosciences and Neurology; Director, Alzheimer Research Laboratory, Case Western Reserve University, School of Medicine

“Nuclear Receptors as Therapeutic Targets in Alzheimer’s Disease”

(Guest of Dr. Jean M. Bidlack)

April 12, 2012 - Research Presentations

Rahul Chandrasekhar

(Graduate student in the laboratory of Dr. David I. Yule)
“Probing the Consequences of PKC Mediated Phosphorylation on Inositol 1,4,5-trisphosphate (InsP3) Receptor Signaling”

April 19, 2012 - Research Presentations

Peter V. DiStefano

(Graduate student in the laboratory of Dr. Angela J. Glading)
“Consequences of Reduced KRIT1 Expression on Endothelial Cell Behavior”

Ellie M. Carrell

(Graduate student in the laboratory of Dr. Robert T. Dirksen)
“Muscle-specific Conditional Knock-out Mouse as a Tool to Study the Structural Role of Orai1”

April 26, 2012 - Research Presentations

Melissa L. Martin

(Graduate student in the laboratory of Dr. Burns C. Blaxall)
“Elucidating the Role of Mixed Lineage Kinase 3 (MLK3) in Pathologic Cardiac Remodeling and Heart Failure”

Kristina L. Modjeski

(Graduate student in the laboratory of Dr. Craig Morrell)
“The Role of a “GRIP”ing Protein on Platelet Activation”

May 3, 2012 - Research Presentations

Qiuyu Zhu

(Graduate student in the laboratory of Dr. Charles J. Lowenstein)
“STXBP5: A Novel Regulator”

Bharti R. Patel

(Graduate student in the laboratory of Dr. Gregory G. Tall)
“Proof of Concept Studies to Determine if Conditional Deletion of Mouse Ric-8A will Ameliorate the Effects of Disease Causing G Protein α Subunit Allele”

in Endothelial Cell Exocytosis”

May 10, 2012 - Paul Horowicz Lecture

W. Jonathan Lederer, M.D., Ph.D.

Professor and Director of BioMET-Center for Biomedical Engineering and Technology, Professor of Physiology, University of Maryland School of Medicine

“Tuning the Heartstrings: How the Heart Regulates its Beat”

(Guest of Dr. Robert T. Dirksen)

May 15, 2012

Vivek Nanda

(Graduate student in the laboratory of Dr. Joseph M. Miano)
“Leiomodin1: A New SRF/MYOCD Dependent Target Gene Expressed Preferentially in Differentiated Vascular Smooth Muscle Cells”

May 22, 2012

Lianghui Zhang

(Graduate student in the laboratory of Dr. Alan V. Smrcka)
“The Mechanism of Phospholipase C Epsilon Regulating Cardiacmyocyte Hypertrophy

May 30, 2012 2012 - Ph.D. Thesis Defense

Nir Maimon

(Graduate student in the laboratory of Dr. Ingrid H. Sarelius)
“The Mechanisms that Mediate Skeletal Muscle Arteriolar Dilatory Response to Adenosine: Novel Pre-Exposure Effect via PKA Activation”