Signal Transduction (IND 447)

Inositide Metabolism and Ca²⁺ Signaling

Trevor J. Shuttleworth, Ph.D.

Ca²⁺ signals and inositol phosphates

References

Assigned readings:

Krause, E., et al. (1999) Low cytoplasmic [Ca²⁺] activates I_CRAC independently of global Ca²⁺ store depletion in RBL-1 cells. J. Biol. Chem. 274 (52): 36957-36962

Adkins, C.E., et al. (2000) Ca²⁺-calmodulin inhibits Ca²⁺ release mediated by type-1, -2 and -3 inositol trisphosphate receptors. Biochem. J. 345: 357-363