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Selected Publications
Alano CC, Beutner G, Piech-Dumas KM, Chisholm JC, Gross RA, and Sheu S-S. Mitochondrial modulation of neuronal excitotoxicity. 2000 Symposium on Neuroscience for Young Scholars Worldwide, Hefei, China, pp. 99-106, 2000. Hüser J, Blatter LA, and Sheu S-S. (2000) Mitochondrial calcium in heart cells: Beat-to-beat oscillations or slow integration of cytosolic transients? J. Bioenerg. Biomembr. 32.1:27-33. Sharma VK, Ramesh V, Franzini-Armstrong C, and Sheu S-S. (2000) Transport of Ca2+ from sarcoplasmic reticulum to mitochondria in rat ventricular myocytes. J. Bioenerg. Biomembr. 32.1:97-104. Beutner G, Sharma VK, Giovannucci DR, Yule DI, and Sheu S-S. (2001) Identification of a ryanodine receptor in rat heart mitochondria. J. Biol. Chem. 276:21482-21488. DeCory HH, Piech-Dumas KM, Sheu S-S, Federoff HF, and Anders MW. (2001) Efflux of the glutathione conjugate of monochlorobimane from striatal and cortical neurons. Drug Metab. Dispos. 29:1256-1262. Sanchez JA, Garcia MC, Sharma VK, Young KC, Matlib MA, and Sheu S-S. (2001) Mitochondria regulate inactivation of L-type Ca2+ channels in rat heart. J. Physiol. 536.2:387-396. Alano CC, Beutner G, Dirksen R, Gross RA, and Sheu S-S. (2002) Mitochondrial permeability transition and calcium dynamics in striatal neurons upon intense NMDA receptor activation. J. Neurochem. 80:531-538. Kriscenski-Perry E, Durham HD, Sheu S-S, and Figlewicz DA. (2002) Synergistic combination of low-level stressors in an oxidative damage model of spinal motor neuron degeneration. ALS & Other Motor Neuron Disorders 3:151-157. He X, Liu Y, Sharma VK, Dirksen RT, Waugh R, Sheu S-S, and Min W. (2003) ASK1 associates with troponin T and induces troponin T phosphorylation and contractile dysfunction in cardiomyocytes. Am. J. Pathol. 163:243-251. Sheu S-S, Anders MW, Xu L, and Sharma VK. (2003) Compounds for delivering amino acids or peptides with antioxidant activity into mitochondria and use thereof. US Provisional Patent Application. No. 60/524,833. Brookes PS, Yoon Y, Robotham JL, Anders MW, and Sheu S-S. (2004) Calcium, ATP & ROS: a mitochondrial love-hate triangle. Am. J. Physiol. (Cell Physiol.) 287:817-833. Anders MW, Robotham JL, and Sheu S-S. Mitochondria-targeted antioxidant prodrugs and methods of use. US Provisional Patent Application, 2005. Beutner G, Sharma VK, Lin L, Ryu SY, Dirksen RT, and Sheu S-S. (2005) Type 1 ryanodine receptor in cardiac mitochondria: Transducer of excitation-metabolism coupling. Biochim. Biophys. Acta 1717:1-10. Brookes PS, Sheu S-S, Anders MW. Method for attenuating mitochondria-mediated cell injury. US Provisional Patent Application, 2005. Itoh S, Lemay S, Osawa M, Che W, Duan Y, Tompkins A, Brookes PS, Sheu S-S, and Abe J-I. (2005) Mitochondrial Dok-4 recruits SRC kinase and regulates NF-κB activation in endothelial cells. J. Biol. Chem. 280:26383-96. Watanabe T, Suzuki J, Yamawaki H, Sharma VK, Sheu S-S, and Berk BC. (2005) Losartan metabolite EXP3179 activates Akt and eNOS via VEGF receptor-2 in endothelial cells: AT1 receptor-independent effects of EXP3179. Circulation 112:1798-805. Anders MW, Robotham JL, Sheu S-S. (2006) Mitochondria: New drug targets for oxidative stress-induced diseases. Expert Opin. Drug Metab. Toxicol., 2:71-79. Brdiczka DG, Zorov DB, and Sheu S-S. (2006) Mitochondrial contact sites: Their role in energy metabolism and apoptosis. Biochim. Biophys. Acta 1762:148-163. Sheu S-S and Lemasters JJ. (2006) Special Issue: “Mitochondria in Diseases and Therapeutics”. Biochim. Biophys. Acta 1762:139. Sheu S-S, Nauduri D, and Anders, M.W. (2006) Targeting antioxidants to mitochondria: A new therapeutic direction. Biochim. Biophys. Acta 1762:256-265. Maekawa, N, Abe J-I, Itoh S, Ding B, Sharma VK, Sheu S-S, Blaxall BC, Berk BC. Inhibiting p90 ribosomal S6 kinase prevents Na-H exchanger-mediated cardiac ischemia-reperfusion injury. Circulation. 2006 (in press).
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