ScienceCache

Vol. 177
July 12, 2004

NANOTECHNOLOGIES HIT A NOT-SO-NANO BUMP
The rage to exploit all things quantum may have hit a snag. Quantum nanorods, atomic structures that have been heralded as the key to everything from super-efficient solar cells to an elusive white laser, appear to have an inherent surface charge that may tarnish their gleaming image, according to a report by scientists in a recent issue of Physical Review Letters. “We’ve found that while perfect nanorods have all this wonderful potential, in reality the current manufacturing process has a serious flaw that gives the rods a charge, and it is this charge that we expect will seriously degrade their usefulness,” says Todd Krauss, assistant professor of chemistry. Quantum rods are lengths of latticed atoms of cadmium and selenium that ought to have no overall charge, but Krauss has discovered that while textbook physics says rods should not have a permanent surface charge, in reality they do. Ideally, quantum nanorods would be constructed of identical layers of bonded atoms. In reality, however, the lattice of cadmium and selenium is skewed, and this imperfect fabrication process creates slightly varied layers that build up to create large disturbances in the overall surface charge profile. Imagine a stack of books where one in the middle is not placed exactly on the one below it; its spine protrudes out one side and its leafed side is sunken into the stack on the other. The overhang allows some of the cover of the book to be visible; in the quantum rod, that visible part of the layer is made of charge-carrying atoms, and their charge disrupts the overall surface charge neutrality of the rod. Improperly stack enough layers in the rod and an appreciable surface charge builds up.
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YOUNGER PATIENTS, WOMEN ANTICIPATE SIDE EFFECTS TO CANCER TREATMENT
Age, gender and educational background influence what side effects a patient expects from their cancer treatment, according to a study of 938 people published today in the online edition of CANCER. Patients under 60 expected more side effects than others over 60; women expected more symptoms than men; and patients with a college education anticipated more side effects than those who had a high school education. Researchers suspect the differences between age groups are tied to natural aging. “Some older people already have seen more symptoms from other illnesses and take the cancer treatment side effects in stride,” says Maarten Hofman of the James P. Wilmot Cancer Center. “For example, older people may have already lost some or all of their hair and don’t see this cancer-related side effect as a problem.” More and more literature has found that a patient’s expectation for a side effect, such as nausea, predicts the development of the symptom. While much time and effort is expended characterizing the side effects of cancer therapies, little is known about what side effects patients expect to experience and what type of patient anticipates them. “We suspect there is a powerful link between the side effect expectations a patient has and the experiences they have. If we are able to provide them with more information and ease their concerns, their cancer treatment experience may be better,” says Hofman.
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KEEPING SUPER-FAST COMPUTERS OUT OF EACH OTHER’S WAY
Sun Microsystems Laboratories has donated over $500,000 in computer equipment to computer scientists in support of efforts to make high-speed computers run faster. Michael Scott, professor of computer science, will use a newly donated 16-processor SunFire 6800 machine to develop synchronization algorithms that allow the processors to coordinate their activities efficiently, loosening a bottleneck that has plagued multiprocessor machines since their invention. “One of the ironies of computing is that when you add more processors, they start to get in each other’s way and slow things down,” says Scott. “The goal of our research is to get these multiprocessor machines to share information in ways that are both correct and fast. A lot of companies use multiprocessors to manage huge databases, but even desktop computers are starting to go multi-processor now, making synchronization more important than ever.” Different processors of a multiple-processor machine often need to read the same section of memory. If one processor needs to update that memory, synchronization can ensure that no other processor sees data in an inconsistent, mid-write state, which could lead to serious errors. Conventionally, the memory would be “locked” until the writer finishes its update, but this has the potential to slow down the entire system if the writer is delayed for any reason. Scott and his students are working with colleagues in the Scalable Synchronization group at Sun Labs to explore alternatives.
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