ScienceCache

Vol. 197
March 30, 2005

ROCHESTER ON THE FRONT LINES TO PREVENT BIRD FLU PANDEMIC
The Rochester area is again playing a key role in the world’s ongoing fight against infectious diseases. Doctors and nurses at the Vaccine Treatment and Evaluation Unit are seeking to enroll 150 people for a study of a vaccine against the most virulent form of bird flu, which has claimed the lives of three out of four people who have been infected with it in Southeast Asia. The study of 450 healthy people at three sites across the nation is being led by John Treanor, professor of medicine and director of the VTEU. The study is evaluating a vaccine made by Sanofi-Aventis and is designed to allow doctors to find the most effective dose to prevent infection. The U.S. government has already purchased 2 million doses of the vaccine and is awaiting the results of the study before deciding how best to formulate the doses. The first study subjects will be vaccinated next week, and several more will receive the vaccine in early May.
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STUDY EXAMINES HOW CHILDREN HANDLE EFFECTS OF DOMESTIC VIOLENCE

A five-year study undertaken by two psychologists will examine the effects of domestic violence on children’s development and family functioning. Called Project Future (Families Understanding Toddlers’ Unique Relationship Experiences), the investigators and a staff of research assistants will follow 250 two-year-olds and their mothers over a two-year period. Because of the devastating effects of domestic violence on children, families, and society, researchers need to gather more information about how and why children exposed to domestic violence are at an increased risk for experiencing mental illness. The researchers will examine children’s development within the framework of emotional security theory, which holds that domestic violence and accompanying functioning of the family increase child vulnerability to mental illness by undermining the child’s sense of security and safety in the family. A $2.8 million grant from the National Institute of Mental Health was awarded recently to principal investigator Patrick Davies of the Department of Clinical and Social Sciences in Psychology and co-principal investigator Dante Cicchetti, director of the Mt. Hope Family Center.
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WEB CHAT THIS MORNING FOCUES ON MENOPAUSE TREATMENTS

A panel of experts convened by the National Institutes of Health to study menopause found that many women can get through hot flashes, night sweats and vaginal dryness without hormones or drugs, and that there has been a tendency to “medicalize” the condition and overuse menopause treatments that may be unsafe. Susan H. McDaniel, a clinical psychologist and associate chair of the Department of Family Medicine, was a member of the 12-person, state-of-the-science panel that spent two days last week deliberating and discussing the most up-to-date science before issuing guidelines on the best and safest therapies. McDaniel and Diane Hartmann, an associate professor of obstetrics and gynecology who has with clinical expertise in the areas of menopause and geriatric gynecology, are discussing the panel’s recommendations this morning via a live Web chat. The session, “Managing Menopause: The Latest Expert Opinions,” is taking place from 9:30 to 10:30 a.m. Anyone interested should log on to www.urmc.rochester.edu/menopause.
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Exploring the nuances of the brain keeps Charles Duffy busy

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