ScienceCache

Vol. 202
Sept. 19, 2005


TEENS BECOME FOCUS OF MERCURY-FISH STUDY

Rochester scientists and doctors are heading to a beautiful tropical island to examine a group of islanders in a study that has implications for anyone in the world who enjoys the taste of seafood. The team is beginning the latest phase of one of the longest-running studies ever to follow the health of a group of people over many years. The 16-year study of more than 700 children in the Seychelles Islands is looking at whether small amounts of mercury in ocean fish such as tuna and swordfish are harmful to people. The issue has been hotly debated, with environmentalists claiming that hundreds of thousands of U.S. children are at risk of serious neurological impairment because their mothers ate fish containing mercury during pregnancy. So far, though, scientists have not observed any adverse effects among children whose mothers ate, on average, 12 meals of fish each week during pregnancy. That is about 10 times as much fish as most Americans eat. “The body of evidence so far indicates that there are not detectable effects in young children,” says Philip Davidson, professor of Pediatrics and chief of the Strong Center for Developmental Disabilities at Golisano Children’s Hospital at Strong, who is leading the study. “But we don’t know about older children until we study them. There is no question that many chemicals and contaminants are neurotoxic. The real question is whether the actual exposure has enough of an effect to be relevant.” The study is continuing for five more years, thanks to another round of funding from the National Institute of Environmental Health Sciences, which recently awarded the group $3.4 million to evaluate the children as teenagers.
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THE DOCTOR SAID: NO MORE CHILDREN JUMPING ON THE BED

Typically, parents worry about their children bumping their heads or wearing out mattresses when they catch them jumping on the bed. But parents should also be wary of injuries from broken wires inside worn-out mattresses. Dante Pappano, an attending physician in the Children’s Emergency Department at Golisano Children’s Hospital at Strong, recently published a paper in Pediatric Emergency Care about a case of a Rochester boy who was injured when a wire snapped inside the mattress and imbedded itself in his foot. Pappano said the 2002 injury surprised him, so he did more research. Pappano visited a local mattress manufacturer and two retail mattress stores. He gutted an old mattress from his own home and another his mother-in-law planned to toss out. Eventually, he hypothesized that the wire was a piece from a long, straight wire that held the boy’s mattress coils upright and hooked onto a frame at either end. Pappano said that type of construction is not common, and he believes it is generally found only in older, inexpensive mattresses. The wire injury does not seem to be common, but Pappano still warned against allowing children to jump on mattresses. “If you have an older, cheap mattress, you’d be better off not jumping on it,” he said.
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CHEMICALS’ EFFECTS ON REPRODUCTION IS FOCUS OF NEW CENTER

Growing evidence suggests that ubiquitous chemicals soaked up by pregnant women around the time of conception or late in pregnancy may be harming the fetus, ultimately having an impact on the child’s future health. To explore this question, the Medical Center has established a Center for Reproductive Epidemiology. Shanna H. Swan, professor of obstetrics and gynecology, will serve as director of the center. She is internationally recognized for her work on links between male and female reproduction and environmental toxins. Since 1998 she has served as principal investigator for a federally funded, multi-center Study for Future Families, an investigation into the environmental causes of geographic variations in reproductive health. Her most recently published research showed that phthalates – hormone-disrupting chemicals used to soften plastics and found in many cosmetics, lotions and shampoos – in a mother’s body during pregnancy had subtle effects on the development of the genitals of infant boys. Swan and colleagues are planning a long-term study of families living in the Rochester area to better understand how phthalates and other environmental exposures can impact infant development.
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